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1221
Use of Platelet Rich Plasma in the Treatment of Diabetic Foot. Case Report
Published 2024-09-01“…The case of a 60-year-old female patient with a medical history of type 2 diabetes mellitus diagnosed 15 years ago, who suffered a puncture wound in the region of the sole of the foot, is presented. …”
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1222
Evaluation of Therapeutic Benefits of a Novel Herbal Ingredient-Based Hyaluronic Acid Gel as Monotherapy for Inflammatory Enlargement of a Patient with Diabetes Mellitus
Published 2022-01-01“…A patient aged 64 years with type 2 diabetes mellitus reported to the Department of Periodontology. …”
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1223
Pharma TARP: A Troubled Asset Relief Program for Novel, Abandoned Projects in the Pharmaceutical Industry
Published 2011-01-01“…Society has a real need for the drugs that are no longer going to be developed for, among others, drug-resistant epilepsy, neuropathic and cancer pain, type-2 diabetes, obesity, and schizophrenia. The authors propose a radical response by the U.S. government and the National Institutes of Health to rescue these abandoned projects, and to continue selected programs for drug approval by the U.S. …”
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1224
Peroxisome Proliferator-Activated Receptor Agonists: Do They Increase Cardiovascular Risk?
Published 2009-01-01“…Cardiovascular disease is a major cause of morbidity and mortality among people with type 2 diabetes mellitus. The peroxisome proliferator-activated receptor (PPAR) agonists have a significant role on glucose and fat metabolism. …”
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1225
Renal and Vascular Mechanisms of Thiazolidinedione-Induced Fluid Retention
Published 2008-01-01“…Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor subtype γ (PPARγ) activators that are clinically used as an insulin sensitizer for glycemic control in patients with type 2 diabetes. Additionally, TZDs exhibit novel anti-inflammatory, antioxidant, and antiproliferative properties, indicating therapeutic potential for a wide variety of diseases associated with diabetes and other conditions. …”
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1226
Antidiabetic Potential of Phytochemicals Found in Vernonia amygdalina
Published 2024-01-01“…Type 2 diabetes mellitus (T2DM), or “insulin-independent diabetes mellitus,” is a worldwide health concern. …”
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1227
Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?
Published 2016-01-01“…The focus of this review is to summarise the known relationships between the expression of heat shock protein 60 (Hsp60) and its association with the pathogenesis of Type 1 and Type 2 diabetes mellitus. Hsp60 is a mitochondrial stress protein that is induced by mitochondrial impairment. …”
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1228
The Relationship between Serum Ferritin and Insulin Resistance in Different Glucose Metabolism in Nonobese Han Adults
Published 2015-01-01“…The exact mechanism through which elevated serum ferritin promotes the development of type 2 diabetes is unknown. This study showed that ferritin concentration in impaired glucose regulation and newly diagnosed diabetes mellitus subjects of nonobesity already significantly increased when compared with normal glucose tolerant subjects of nonobesity. …”
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1229
Comorbidities and Ethnocultural Factors Limit the Physical Activity of Rural Sri Lankan Patients with Diabetes Mellitus
Published 2018-01-01“…Four hundred patients with type 2 diabetes, comprising 113 (28.2%) males and 287 (71.7%) females, were enrolled. …”
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1230
Enhancing Exercise Responsiveness across Prediabetes Phenotypes by Targeting Insulin Sensitivity with Nutrition
Published 2017-01-01“…Herein, we propose the novel hypothesis that the combination of individualized nutrition therapy and exercise should be based on the clinical pathology of prediabetes to overcome exercise resistance and improve responsiveness in people at risk for type 2 diabetes and cardiovascular disease.…”
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1231
The therapeutic agents that target ATP-sensitive potassium channels
Published 2016-03-01“…ATP-sensitive potassium (KATP) channels are a major drug target for the treatment of type-2 diabetes. KATP channels are ubiquitously expressed and link the metabolic state to electrical excitability. …”
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1232
Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role?
Published 2025-01-01“…This study evaluated endothelial dysfunction and oxidative stress in patients with severe coronary artery disease (CAD) undergoing coronary artery bypass graft (CABG) surgery, comparing those with and without type 2 diabetes mellitus (T2DM). <i>Materials and Methods:</i> We included 84 patients with severe coronary artery disease (33 of whom had type 2 diabetes mellitus) who underwent clinical assessments, ultrasound, and coronaryangiography. …”
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1233
Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study
Published 2025-01-01“…The ACS group, compared to control group, had higher proportions of type-2 diabetes (41.6%vs.11.7%, p< 0.001), hypertension (53.9%vs.23.4%, p< 0.001), tobacco use (37.7%vs.24.2%, p=0.001), family history of cardiovascular disease (53.2%vs.23.4%, p< 0.001), metabolic syndrome (14.3%vs.2.4%, p< 0.001), and preterm delivery (24.7%vs.16.7%, p=0.032). …”
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1234
Post Varicella Necrotising Fasciitis Afflicting Upper Limb in Young Child: A Rare Case Report
Published 2024-03-01“…Risk factors include immunosuppression, type 2 diabetes mellitus, chronic diseases like cirrhosis of liver and chronic kidney disease, malignancies, intravenous drug use, obesity, and age more than 60 years. …”
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1235
Antenatal Corticosteroids: A Risk Factor for the Development of Chronic Disease
Published 2012-01-01“…However, exogenous ACS reduces birth weight which, in turn, is associated with adverse adult outcomes such as coronary heart disease, stroke, hypertension, and type 2 diabetes. The long-term effects of ACS exposure on HPA axis activity and neurological function are well documented in animal studies, and it appears that ACS, regardless of dose exposure, is capable of affecting fetal HPA axis development causing permanent changes in the HPA axis that persists through life and is manifested by chronic illness and behavioral changes. …”
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1236
Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols
Published 2017-01-01“…Additionally, certain polyphenols found in spices might improve glucose homeostasis and insulin resistance in diabetes patients, thereby constituting promising options for the treatment of type 2 diabetes.…”
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1237
Exercise as a Mean to Control Low-Grade Systemic Inflammation
Published 2008-01-01“…Chronic noncommunicable diseases (CNCDs), which include cardiovascular disease, some cancers, for example, colon cancer, breast cancer, and type 2 diabetes, are reaching epidemic proportions worldwide. …”
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1238
The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP
Published 2015-01-01“…Type 2 diabetes mellitus (T2DM) is an age-related and metabolic disease. …”
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1239
The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes
Published 2012-01-01“…Pharmaceutical agonists of peroxisome proliferator-activated receptors (PPARs) are widely used in the management of type 2 diabetes, chiefly as lipid-lowering agents and oral hypoglycaemic agents. …”
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1240
Autophagy-lysosome pathway in insulin & glucagon homeostasis
Published 2025-02-01“…Glucose homeostasis relies on tightly regulated insulin secretion by pancreatic β cells, and their dysfunction is a hallmark of type 2 diabetes. Glucagon also plays an important role in hyperglycemia in diabetic patients. …”
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