First Report of Diabetes Phenotype due to a Loss-of-Function ABCC8 Mutation Previously Known to Cause Congenital Hyperinsulinism by Theocharis Koufakis, Amalia Sertedaki, Elizabeth-Barbara Tatsi, Christina-Maria Trakatelli, Spyridon N. Karras, Eleni Manthou, Christina Kanaka-Gantenbein, Kalliopi Kotsa

“…Monogenic Diabetes is relatively rare, representing only 1-2% of total diabetes cases; nevertheless, it is often misdiagnosed primarily as type 1 diabetes, leading to unnecessary insulin therapy and delayed recognition of affected family members. …”
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Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications by Lyubomir Gaydarski, Kristina Petrova, Ivan Angushev, Stancho Stanchev, Alexandar Iliev, Nikola Stamenov, Vidin Kirkov, Boycho Landzhov

“…Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease (CKD) and end-stage renal disease worldwide, affecting approximately 40% of individuals with type 2 diabetes (T2DM) and 30% of those with type 1 diabetes (T1DM). As the prevalence of diabetes continues to rise, the burden of DKD is expected to grow correspondingly. …”
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Evaluation of Stability of Surface-Treated Mini-Implants in Diabetic Rabbits by Nam-Hee Oh, Eun-Young Kim, Janghyun Paek, Yoon-Ah Kook, Do-Min Jeong, Il-Sik Cho, Gerald Nelson

“…However, there was no significantly statistical difference. Conclusions. Type 1 diabetes mellitus and surface treatment method of mini-implant affected primary stability of mini-implants. …”
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Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Vinicius F. Carvalho, Emiliano O. Barreto, Ana Carolina S. Arantes, Magda F. Serra, Tatiana Paula T. Ferreira, Yago A. P. Jannini-Sá, Cory M. Hogaboam, Marco A. Martins, Patrícia M. R. Silva

“…Previous studies described that allergic diseases, including asthma, occur less often than expected in patients with type 1 diabetes. Here, we investigated the influence of diabetes on allergic airway inflammation in a model of experimental asthma in mice. …”
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Retrospective Analysis of Bone Metabolism in Patients on Waiting List for Simultaneous Pancreas-Kidney Transplantation by Simona Kratochvílová, Jana Brunová, Petr Wohl, Věra Lánská, František Saudek

“…The aim of our study was to evaluate epidemiological data on bone mineral density (BMD) in subjects with type 1 diabetes (T1DM) in advanced stages of diabetic nephropathy indicated for simultaneous pancreas-kidney transplantation (SPK). …”
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Mortality and Years of Life Lost in Diabetes Mellitus and Its Subcategories in China and Its Provinces, 2005–2020 by Feixue Wang, Wei Wang, Peng Yin, Yunning Liu, Jiangmei Liu, Lijun Wang, Jinlei Qi, Jinlin You, Lin Lin, Maigeng Zhou

“…The ASMR of type 2 diabetes mellitus (T2DM) was much higher than that of type 1 diabetes mellitus (T1DM). The ASMR of T1DM remained stable, but the rate of T2DM increased, and the increase in male patients was higher than that in their female counterparts. …”
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Effect of Rosiglitazone and Insulin Combination Therapy on Inflammation Parameters and Adipocytokine Levels in Patients with Type 1 DM by Metin Guclu, Ozen Oz Gul, Soner Cander, Oguzkaan Unal, Guven Ozkaya, Emre Sarandol, Canan Ersoy

“…To investigate the efficacy of combined therapy of insulin and rosiglitazone on metabolic and inflammatory parameters, insulin sensitivity, and adipocytokine levels in patients with type 1 diabetes mellitus (type 1 DM). Material and Methods. …”
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PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice by Ying Sun, Zhanjun Jia, Gang Liu, Li Zhou, Mi Liu, Baoxue Yang, Tianxin Yang

“…Evidence had shown the detrimental effect of prostaglandin (PG) E2 in diabetic nephropathy (DN) of STZ-induced type-1 diabetes but its role in the development of DN of type-2 diabetes remains uncertain. …”
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Administration of a Next-Generation Probiotic Escherichia coli Nissle 1917-GLP-1 Alleviates Diabetes in Mice With Type 1 and Type 2 Diabetes by Jie Luo, Yilin Fang, Zhanghua Qi, Fengyang Cui, Hong Hu, Shengjie Li, Tingtao Chen, Hongyan Zhang

“…We utilized mouse models for both Type 1 diabetes mellitus (T1DM) and Type 2 diabetes mellitus (T2DM) to assess its efficacy. …”
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Awareness About Diabetes And Its Complications Among Patients With Diabetes Mellitus by Faiza Batool, Kausar Malik, Lubna Meraj, Shazia Siddiq, Abbas Majeed, Sadia Khan

“…Methods: A cross-sectional study included 200 patients with type 2 diabetes mellitus as per the American Diabetes Association (ADA) criteria. Type 1 diabetes and gestational diabetes patients were excluded from the study. …”
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Islet organoids: a new hope for islet transplantation in diabetes by Xuemei Yu, Chengkong Liu, Zheng Kuang, Siyuan Song, Limin Tian, Yi Wang, Yi Wang

“…Diabetes mellitus, including Type 1 diabetes (T1D) and advanced Type 2 diabetes (T2D), remains a major global health challenge due to the destruction or dysfunction of insulin-producing β-cells. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…Type 1 diabetes (T1D) is a chronic autoimmune disease and characterized by absolute insulin deficiency. β-cell replacement by islet cell transplantation has been established as a feasible treatment option for T1D. …”
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Continuous Quadrupole Magnetic Separation of Islets during Digestion Improves Purified Porcine Islet Viability by Bradley P. Weegman, Venkata Sunil Kumar Sajja, Thomas M. Suszynski, Michael D. Rizzari, William E. Scott III, Jennifer P. Kitzmann, Kate R. Mueller, Thomas R. Hanley, David J. Kennedy, Paul W. Todd, Appakalai N. Balamurugan, Bernhard J. Hering, Klearchos K. Papas

“…Islet transplantation (ITx) is an emerging and promising therapy for patients with uncontrolled type 1 diabetes. The islet isolation and purification processes require exposure to extended cold ischemia, warm-enzymatic digestion, mechanical agitation, and use of damaging chemicals for density gradient separation (DG), all of which reduce viable islet yield. …”
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Antibodies to Lactobacilli and Bifidobacteria in Young Children with Different Propensity to Develop Islet Autoimmunity by Ija Talja, Anna-Liisa Kubo, Riitta Veijola, Mikael Knip, Olli Simell, Jorma Ilonen, Mari Vähä-Mäkilä, Epp Sepp, Marika Mikelsaar, Meeme Utt, Raivo Uibo

“…Immunoblot assays were used to establish the prevalence of serum IgG, IgM, and IgA antibodies specific for Bifidobacterium adolescentis, Bifidobacterium longum, and Lactobacillus rhamnosus GG proteins in young children presenting with or without type 1 diabetes (T1D). We demonstrated that children between the ages of 6 and 12 months had a substantial increase in the frequency of IgG antibodies specific for L. rhamnosus GG proteins. …”
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FABP4 and I-FABP Levels in Pregnant Women Are Associated with Body Mass Index but Not Gestational Diabetes by Tamara Vorobjova, Aili Tagoma, Ija Talja, Helis Janson, Anne Kirss, Raivo Uibo

“…Increased level of intestinal fatty acid-binding protein (I-FABP) may indicate impaired intestinal permeability, which may be an important contributor to the pathogenesis of type 1 diabetes and GDM. We aimed to compare FABP4 and I-FABP levels in pregnant women with GDM and in healthy pregnant controls, taking into consideration their prepregnancy body mass index (BMI), past exposures to enteroviruses (EV), and adipokine and cytokine levels, which have been shown to decrease insulin sensitivity. …”
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Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues by Shih-Yi Kao, Jia-Fwu Shyu, Hwai-Shi Wang, Chi-Hung Lin, Cheng-Hsi Su, Tien-Hua Chen, Zen-Chung Weng, Pei-Jiun Tsai

“…Background. Type 1 diabetes mellitus results from autoimmune destruction of β-cells. …”
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Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization by Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask, Paul de Vos, Corinne A Hoesli

“…Islet transplantation and more recently stem cell-derived islets were shown to successfully re-establish glycemic control in people with type 1 diabetes under immunosuppression. These results were achieved through intraportal infusion which leads to early graft losses and limits the capacity to contain and retrieve implanted cells in case of adverse events. …”
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Ketosis Onset Type 2 Diabetes Had Better Islet β-Cell Function and More Serious Insulin Resistance by Hongyun Lu, Fang Hu, Yingjuan Zeng, Lingling Zou, Shunkui Luo, Ying Sun, Hong Liu, Liao Sun

“…Diabetic ketosis had been identified as a characteristic of type 1 diabetes mellitus (T1DM), but now emerging evidence has identified that they were diagnosed as T2DM after long time follow up. …”
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Cross‐sectional association of irregular dietary habits with glycemic control and body mass index among people with diabetes by Mika Shimizu, Junko Oya, Yuichiro Kondo, Aki Katamine, Yukiko Hasegawa, Tomoko Nakagami

“…Materials and Methods We included 4,421 people with diabetes aged 20–74 years (type 1 diabetes (T1D), 19.1%) who answered a questionnaire at mealtime. …”
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Recurrent nocturnal hypoglycemic hemiplegia: a case report and review of the literature by Hanako Toyama, Kazuyuki Takahashi, Tatsunori Shimizu, Izumi Otaka, Sakiko Abe, Shunsuke Kato, Sayaka Ando, Takehiro Sato, Tsukasa Morii, Hiroki Fujita, Hironori Waki

“…A 67-year-old man with type 1 diabetes, Cronkhite-Canada syndrome, and membranous nephropathy who received insulin therapy was admitted to our hospital with right hemiplegia and dysarthria. …”
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