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FREQUENCY OF CHRONIC COMPLICATION IN TYPE 2 DIABETES AT ATERTIARY CARE HOSPITAL IN THE PROVINCE OF PUNJAB
Published 2024-06-01“…Entities with gestational and type 1 diabetes were barred from the study. Statistical analysis was performed using Statistical Packages for Social Sciences (SPSS) version 20. …”
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322
Genetic, Functional, and Immunological Study of ZnT8 in Diabetes
Published 2019-01-01“…A common ZnT8 gene (SLC30A8) polymorphism increases the risk of type 2 diabetes mellitus (T2DM), and rare mutations may present protective effects. In type 1 diabetes mellitus (T1DM), autoantibodies show specificity for binding two variants of ZnT8 (R or W at amino acid 325) dictated by a polymorphism in SLC30A8. …”
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323
Acute Hyperglycemia Due to Topical Corticosteroid Administration
Published 2019-01-01“…We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose. …”
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324
Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy
Published 2012-01-01“…Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs. …”
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325
Atypical Celiac Disease: From Recognizing to Managing
Published 2012-01-01“…The availability of high-sensitive and specific serologic tests such as antitissue transglutuminase, antiendomysium, and more recent antideamidated, gliadin peptide antibodies permits to efficiently uncover a large portion of the submerged CD iceberg, including individuals having conditions associated with a high risk of developing CD (type 1 diabetes, autoimmune diseases, Down syndrome, family history of CD, etc.), biologic abnormalities (iron deficiency anemia, abnormal transaminase levels, etc.), and extraintestinal symptoms (short stature, neuropsychiatric disorders, alopecia, dental enamel hypoplasia, recurrent aphtous stomatitis, etc.). …”
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326
Changes in the Diaphragm Lipid Content after Administration of Streptozotocin and High-Fat Diet Regime
Published 2017-01-01“…Male Wistar rats were randomly allocated into 3 groups: control, streptozotocin-induced (STZ) type-1 diabetes, and rodents fed with high-fat diet (HFD). …”
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327
Deep learning-based prediction of autoimmune diseases
Published 2025-02-01“…In particular, the average area under the ROC curve (AUC) of the AutoY model exceeded 0.93 in the prediction of all the diseases, and the AUC value reached 0.99 in two diseases, type 1 diabetes and multiple sclerosis. These results demonstrate the high accuracy, stability, and good generalization ability of the two models, which makes them promising tools in the field of autoimmune disease prediction and provides support for the use of the TCR bank for the noninvasive detection of autoimmune disease non-invasive detection is supported.…”
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328
Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis
Published 2017-01-01“…Polymorphism in VDR causes alterations in the functioning of vitamin D, leading to type 1 diabetes (T1D) predisposition. The aim of the present study was to determine VDR gene polymorphism in association with T1D in Pakistanis. …”
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329
Effect of Epidermal Growth Factor in a Patient with Diabetic Hand
Published 2025-01-01“…Herein, we report the case of a 38-year-old man with type 1 diabetes and restless leg syndrome who presented to our out-patient clinic with a necrotic wound on his right thumb. …”
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330
Low Grade Islet but Marked Exocrine Pancreas Inflammation in an Adult with Autoimmune Pre-Diabetes
Published 2019-01-01“…There is unexplained deficit in size and function of the exocrine pancreas in type 1 diabetes (T1D). We obtained pancreas from an individual with pre-T1D obtained at surgery and addressed the question, what is the relative inflammation in the exocrine and endocrine pancreas in pre-T1D in the absence of the potential confounding changes at autopsy or in brain dead organ donors. …”
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331
Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes
Published 2018-01-01“…Urine from 39 patients affected by type 1 diabetes, 32 patients with type 2 diabetes, and 52 controls were analysed. …”
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332
Extending TextAE for annotation of non-contiguous entities
Published 2020-06-01“…Most tools do not capture non-contiguous entities which are separate spans of text that together refer to an entity, e.g., the entity “type 1 diabetes” in the phrase “type 1 and type 2 diabetes.” …”
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333
Increased Yield and Improved Transplantation Outcome of Mouse Islets with Bovine Serum Albumin
Published 2012-01-01“…Isolation and transplantation of rodent islets are frequently used as a tool for predicting the behavior of new protocols for islet allotransplants in type 1 diabetes patients. Bovine serum albumin (BSA) is recognized as a protease inhibitor possibly protecting function and viability in islets. …”
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334
Diabetes-Resistant NOR Mice Are More Severely Affected by Streptozotocin Compared to the Diabetes-Prone NOD Mice: Correlations with Liver and Kidney GLUT2 Expressions
Published 2015-01-01“…Nonobese Diabetic (NOD) mice are susceptible strains for Type 1 diabetes development, and Nonobese Diabetes-Resistant (NOR) mice are defined as suitable controls for NOD mice in non-MHC-related research. …”
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335
Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRIN-BD11
Published 2020-01-01“…Blood glucose, plasma insulin, and glucagon levels were measured following a duodenal glucose tolerance test (IDGTT), in four pigs with STZ-induced type 2 diabetes (T2D pigs) and in four pigs with STZ-induced type 1 diabetes (T1D pigs). Four intact pigs were used as the control group. …”
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336
Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies
Published 2016-01-01“…As numerous studies put in evidence the increasing incidence of type 1 diabetes (T1D) in children, an early diagnosis is of great importance to define correct treatment and diet. …”
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337
The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers
Published 2019-01-01“…Insulin is the mainstay drug in type 1 diabetes mellitus (T1D); however, the use of insulin is associated with haematological alterations that could further worsen cardiovascular complications. …”
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338
A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient
Published 2025-02-01“…She had undergone living donor kidney transplantation 11 years earlier and brain-dead donor pancreas transplantation 1 year earlier owing to type 1 diabetes. Cesarean section was indicated when the patient’s blood pressure was 150/100 mmHg at 37 weeks. …”
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339
Role of radiological methods of diagnostics at simultaneous pancreas-kidney transplantation
Published 2015-12-01“…From January, 2008 to June, 2014 overall 40 patients with the type 1 diabetes mellitus complicated by terminal diabetic nephropathy, underwent SPKT, including 17 cases (42,5%) — of intraperitoneal transplantation and 23 (57,5%) — of retroperitoneal transplantation. …”
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340
Rule-based ai system for early paediatric diabetes diagnosis using backward chaining and certainty factors
Published 2025-01-01“…Furthermore, the incidence of type 1 diabetes mellitus in children is on the rise in Indonesia but we do not have an accurate figure due to a high misdiagnosis rate. …”
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