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281
B Cells in Autoimmune Diseases
Published 2012-01-01“…This paper includes an overview of the different functions of B cells in autoimmunity; the involvement of B cells in systemic lupus erythematosus, rheumatoid arthritis, and type 1 diabetes; and current B-cell-based therapeutic treatments. …”
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282
Successful treatment of stiff-person syndrome with plasmapheresis: case report and literature review
Published 2023-10-01“…The most notable SPS comorbidities include temporal lobe epilepsy and type 1 diabetes mellitus. In this article, we present a clinical case of a patient illustrating the course of the disease, diagnostic difficulties, and treatment options, all of which are discussed in the literature review. …”
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283
IPEX as a Result of Mutations in FOXP3
Published 2007-01-01“…Their deficiency is the hallmark of IPEX and leads to severe autoimmune phenomena including autoimmune enteropathy, dermatitis, thyroiditis, and type 1 diabetes, frequently resulting in death within the first 2 years of life. …”
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284
Diabetic Mastopathy as a Radiographically Occult Palpable Breast Mass
Published 2011-01-01“…We describe a patient with long-standing type 1 diabetes who presented with a palpable breast mass with negative imaging findings on mammography, ultrasonography, and breast MRI. …”
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285
Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation
Published 2013-01-01“…Two clinical trials in type-1 diabetes and rheumatoid arthritis have been carried out, and other trials, including one trial in kidney transplantation, are in progress or are imminent.…”
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286
Diabetic Cheiroarthropathy: A Case Report and Review of the Literature
Published 2013-01-01“…We review a case of a 28-year-old female patient with type 1 diabetes mellitus who was diagnosed with DCA after complaining of limited movements of all joints in her hands and tightening of the skin. …”
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287
Severe Transient Hyperglycemia in a Prediabetic Patient during Mild Acute Pancreatitis
Published 2015-01-01“…He was initially misdiagnosed with type 1 diabetes and treated with insulin for one month. …”
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288
Homeostatic T Cell Proliferation after Islet Transplantation
Published 2013-01-01“…Pancreatic islet transplantation in patients with type 1 diabetes mellitus is performed under immunosuppression to avoid alloreactive T cell responses and to control the reactivation of autoreactive memory T cells. …”
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289
Mendelian randomization analysis does not support a causal influence between lipoprotein(A) and immune-mediated inflammatory diseases
Published 2025-01-01“…However, genetically predicted lipid traits HDL-C was associated with increased risk of Type 1 diabetes (T1D). The identification of potential mechanisms underlying the observed associations in observational studies necessitates further investigation.…”
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290
Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study
Published 2021-01-01“…In fully adjusted models, participants with type 1 diabetes patients with versus without DSPN had an increased mortality (HR 2.99, 95% CI 1.4-8.63), while no association with CAN was observed. …”
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291
Glutamine Supplementation in Sick Children: Is It Beneficial?
Published 2011-01-01“…This includes premature infants, infants with gastrointestinal disease, children with Crohn's disease, short bowel syndrome, malnutrition/diarrhea, cancer, severe burns/trauma, Duchenne muscular dystrophy, sickle cell anemia, cystic fibrosis, and type 1 diabetes. Moreover, methodological issues have been noted in some studies. …”
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292
Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
Published 2025-01-01“…We highlight the application of immunopeptidomics in Type 1 Diabetes (T1D), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA). …”
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293
Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease
Published 2015-01-01“…Several studies have been performed on the association of the genetic alterations in genes encoding NLRP3 and CARD8 with the complex diseases with inflammatory background, like inflammatory bowel disease, cardiovascular diseases, rheumatoid arthritis, and type 1 diabetes. The aim of the present review is therefore to summarize the literature regarding genetic alterations in these genes and their association with health and disease.…”
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294
The Histone Modification Code in the Pathogenesis of Autoimmune Diseases
Published 2017-01-01“…In this paper, we discuss the significant roles of histone modifications involved in the pathogenesis of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, primary biliary cirrhosis, and type 1 diabetes.…”
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295
The Fate of Allogeneic Pancreatic Islets following Intraportal Transplantation: Challenges and Solutions
Published 2018-01-01“…Pancreatic islet transplantation as a therapeutic option for type 1 diabetes mellitus is gaining widespread attention because this approach can restore physiological insulin secretion, minimize the risk of hypoglycemic unawareness, and reduce the risk of death due to severe hypoglycemia. …”
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296
Treatment of Diabetes Mellitus Using iPS Cells and Spice Polyphenols
Published 2017-01-01“…Here, we reviewed the current reprogramming of somatic cells using specific factors to induced pluripotent stem (iPS) cells capable of repairing islet β cell damage in diabetes patients to treat patients with type 1 diabetes mellitus. We also discuss the shortcomings associated with clinical use of iPS cells. …”
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297
Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics
Published 2024-01-01“…Specific genetic variants in genes that are responsible for maintaining the composition of the gut commensal, such as genes of the immune system, are described to result in gut dysbiosis that can lead to the development of several autoimmune diseases such as inflammatory bowel disease and type-1 diabetes. Similarly, the diet of an individual shapes the gut microbiota by allowing the predominance of microbes that metabolize an abundant macromolecule in the diet. …”
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298
Evolution of 𝜷-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell Transplantation
Published 2011-01-01“…Of these individuals, 5 to 10% have been diagnosed with Type 1 diabetes mellitus (T1DM), an autoimmune disease. …”
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299
A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning.
Published 2025-01-01“…Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. …”
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300
The Role of the PGC1α Gly482Ser Polymorphism in Weight Gain due to Intensive Diabetes Therapy
Published 2009-01-01“…The Diabetes Control and Complications Trial (DCCT) involved intensive diabetes therapy of subjects with type 1 diabetes mellitus (T1DM) for an average period of 6.5 years. …”
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