Could hypoxic conditioning augment the potential of mesenchymal stromal cell-derived extracellular vesicles as a treatment for type 1 diabetes? by Cathal Patrick Forkan, Aruna Shrestha, Alfred Yu, Christine Chuang, Flemming Pociot, Reza Yarani

“…Abstract Type1 Diabetes (T1D) is an autoimmune disorder characterised by the loss of pancreatic β-cells. …”
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The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control by Kailash Singh, Stellan Sandler, Daniel Espes

“…To characterize the plasma levels of vascular endothelial growth factor (VEGF) in type 1 diabetes mellitus (T1D) and its relation to both present and historical metabolic control and microvascular complications. …”
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Benidipine Protects Kidney through Inhibiting ROCK1 Activity and Reducing the Epithelium-Mesenchymal Transdifferentiation in Type 1 Diabetic Rats by Ganlin Wu, Meirong Xu, Kui Xu, Yilan Hu

“…STZ were used to make the rats type 1 diabetic and were randomly assigned as diabetes without treatment (D), diabetes treated with benidipine (B), and diabetes treated with fasudil (F) and treated for 3 months. …”
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Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163 by Brigitte Sonier, Alexander Strom, Gen-Sheng Wang, Christopher Patrick, Jennifer A Crookshank, Majid Mojibian, Amanda J MacFarlane, Fraser W Scott

“…Antibodies against the wheat storage globulin Glo-3A from a patient with both type 1 diabetes (T1D) and celiac disease were enriched to identify potential molecular mimicry between wheat antigens and T1D target tissues. …”
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Comment les équipes éducatives prennent-elles en compte la situation d’enfants atteints du diabète de type 1 ? Analyse du propos des enseignants en Belgique francophone by Pauline Delannoy, Hélène Geurts, Antoine Derobertmasure

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OXIDATIVE STRESS AND ORAL HEALTH IN PEDIATRIC TYPE 1 DIABETES: A COMPARATIVE STUDY OF ANTIOXIDANT ENZYME ACTIVITY AND LIPID PEROXIDATION MARKERS by Amelia Surdu, Daniela Trifan, Irina-Georgeta Sufaru, Oana Cristina Cretu, Mihaela Monica Scutariu

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Hospitalisation from seasonal influenza among persons with type 1 diabetes: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Björn Eliasson, Hanne Krage Carlsen, Lena Svensson, Magnus Gisslén, Elin Allansson Kjölhede, Oliver Martyn

“…Objectives The aim of this study was to investigate the risk of severe influenza resulting in hospitalisation among adults with type 1 diabetes (T1D).Design Nationwide cohort study using register data.Settings Data from the National Diabetes Register (NDR) linked to the Swedish Patient Register, Statistics Sweden and the Swedish Population Register.Participants Persons with T1D in the Swedish NDR n=35 596 and control persons from the Swedish Population Register matched on age, sex and county of residence, n=155 590.Primary and secondary outcomes Hospitalisation from seasonal influenza from October 2013 to December 2019. …”
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Experiences and opinions of adults with type 1 diabetes on the android-based open-source closed-loop system in China: a qualitative study by Chaofan Wang, Daizhi Yang, Jinhua Yan, Ping Ling, Mengyun Lei, Ying Ni, Xiaodi Guo, Qingying Huang

“…Objective As an emerging technology, Android-based open-source closed-loop system also called Android Artificial Pancreas System (AAPS), has been increasingly validated by evidence for its effectiveness in improving glycaemic outcomes, positioning it as a crucial option for managing type 1 diabetes (T1D). However, there are still only a few studies examining the experiences of using AAPS, and relevant qualitative studies have not been conducted in Asia so far. …”
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Low-dose interleukin-2-loaded nanoparticle effect on NK and T-reg cell expression in experimentally induced type 1 diabetes mellitus by Salma Aboelnazar, Hossam Ghoneim, Mai Moaaz, Eman Taha Bahgat, Thanaa Shalaby

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Combination of GLP-1 Receptor Activation and Glucagon Blockage Promotes Pancreatic β-Cell Regeneration In Situ in Type 1 Diabetic Mice by Liangbiao Gu, Dandan Wang, Xiaona Cui, Tianjiao Wei, Kun Yang, Jin Yang, Rui Wei, Tianpei Hong

“…Glucagon receptor (GCGR) monoclonal antibody (mAb), a preclinical agent that blocks glucagon pathway, can promote the recovery of functional β-cell mass in type 1 diabetic mice. Here, we conducted a 4-week treatment of the two drugs alone or in combination in type 1 diabetic mice. …”
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Serum Concentrations of Transforming Growth Factor-Beta 1 in Predicting the Occurrence of Diabetic Retinopathy in Juvenile Patients with Type 1 Diabetes Mellitus by Katarzyna Zorena, Ewa Malinowska, Dorota Raczyńska, Małgorzata Myśliwiec, Krystyna Raczyńska

“…In the present study, we have decided to evaluate if serum transforming growth factor-beta 1 (TGF-β1) concentrations may have diagnostic value in predicting the occurrence of diabetic retinopathy (DR) in juvenile patients with type 1 diabetes mellitus (T1DM). The study included 81 children and adolescents with T1DM and 19 control subjects. …”
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Not Only Glycaemic But Also Other Metabolic Factors Affect T Regulatory Cell Counts and Proinflammatory Cytokine Levels in Women with Type 1 Diabetes by Katerina Stechova, Jana Sklenarova-Labikova, Tereza Kratzerova, Pavlina Pithova, Dominik Filipp

“…Type 1 diabetic (T1D) patients suffer from insulinopenia and hyperglycaemia. …”
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Caregiver’s Opinions on the Design of the Screens of a Future Gamified Mobile Application for Self-Management of Type 1 Diabetes in Children in Saudi Arabia by Demah M. Alsalman, Zahra Bu Ali, Zainab Alnosaier, Norah Alotaibi, Turki M. Alanzi

“…The objective of this study was to design the screens of a future gamified mobile application for self-management of type 1 diabetes in children based on the opinion of caregivers at the King Fahad Hospital Diabetes Center, Saudi Arabia. …”
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Cardiovascular function shows early impairment in asymptomatic adolescents diagnosed with type 1 diabetes mellitus: an ultrasound-derived myocardial work study by Martina Ghirardo, Martina Ghirardo, Irene Cattapan, Irene Cattapan, Jolanda Sabatino, Jolanda Sabatino, Alice Pozza, Alice Pozza, Jennifer Fumanelli, Jennifer Fumanelli, Martina Avesani, Joaquin Gutierrez De Rubalcava Doblas, Carlo Moretti, Biagio Castaldi, Giovanni Di Salvo

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Lower Frequency of CD62Lhigh and Higher Frequency of TNFR2+ Tregs Are Associated with Inflammatory Conditions in Type 1 Diabetic Patients by Monika Ryba, Karolina Rybarczyk-Kapturska, Katarzyna Zorena, Małgorzata Myśliwiec, Jolanta Myśliwska

“…We propose that these may be associated with inflammatory conditions that are present in patients with type 1 diabetes. The lower percentage of Tregs and Treg CD62Lhigh may contribute to ineffective suppression of proinflammatory cytokines production during type 1 diabetes.…”
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Osteoprotegerin, Soluble Receptor Activator of Nuclear Factor-κB Ligand, and Subclinical Atherosclerosis in Children and Adolescents with Type 1 Diabetes Mellitus by Irene Lambrinoudaki, Emmanouil Tsouvalas, Marina Vakaki, George Kaparos, Kimon Stamatelopoulos, Areti Augoulea, Paraskevi Pliatsika, Andreas Alexandrou, Maria Creatsa, Kyriaki Karavanaki

“…To evaluate carotid intima-media thickness (cIMT) and biomarkers of the osteoprotegerin/receptor activator of nuclear factor-κB ligand (OPG/RANKL) system in type 1 diabetes (T1DM) children and adolescents and controls. …”
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Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses by Patrick Nelson, Noah Smith, Stanca Ciupe, Weiping Zou, Gilbert S. Omenn, Massimo Pietropaolo

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Corrigendum to “Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease” by Misun Hwang, Dana L. Tudorascu, Karen Nunley, Helmet Karim, Howard J. Aizenstein, Trevor J. Orchard, Caterina Rosano

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Curcumin administration alleviates seminal vesicle damage in type 1 diabetic rats by promoting AQP8 expression through AR activation by Dawei Ni, Kun Liu, Ning Wu, Bin You, Baibing Yang, Wei Wu, Yutian Dai

“…These findings suggest that curcumin may alleviate seminal vesicle damage in type 1 diabetic rats by activating the AR-AQP8 pathway.…”
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Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study by Manel Mateu‐Salat, Nicole Stanton‐Yonge, Frederic Sampedro Santaló, José Ignacio Vela, Jesús Díaz Cascajosa, Eva Safont Pérez, Daniela Rego‐Lorca, Ana Chico

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