Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III... by Roger Owen, John Jones, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Neil Rabin, Matthew Jenner, Martin Kaiser, Kevin Boyd, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Charlotte Pawlyn, Anna Hockaday, Jennifer Bird, Stella Bowcock, Ruth de Tute, Hayley Gardner, Bryony Dawkins, Rowena Henderson, Phillip Best, Bhuvan Kishore, Mark Drayson

“…Following 12 cycles of induction treatment, participants alive and progression free will undergo a second (double-blind) randomisation on a 1:1 basis to maintenance treatment with lenalidomide+placebo versus lenalidomide+ixazomib until disease progression or intolerance.Ethics and dissemination Ethical approval has been obtained from the North East—Tyne & Wear South Research Ethics Committee (19/NE/0125) and capacity and capability confirmed by local research and development departments for each participating centre prior to opening to recruitment. …”
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Rainfed agriculture in Ethiopia: a systematic review of green water management pathways to improve water and food security by Ermias Teferi, Ermias Teferi, Tibebu Kassawmar, Tibebu Kassawmar, Woldeamlak Bewket, Woldeamlak Bewket, Gete Zeleke, Gebiaw T. Ayele, Greg O’Donnell, Claire Walsh

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Moving from monitoring to real-time interventions for air quality: are low-cost sensor networks ready to support urban digital twins? by Nicole Hannah Cowell, Nicole Hannah Cowell, Lee Chapman, David Topping, Philip James, Daniel Bell, Thomas Bannan, Ettore Murabito, James Evans, Mark Birkin

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Angiomyolipoma in a Patient with Situs Inversus Totalis: Managing Two Rare Diseases by Jonathan Mayes, Nigel Heaton

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Integrated Sensor Fault Diagnosis and Fault-Tolerant Control for Manipulator by Bowen Hong, Lina Yao, Zhiwei Gao

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Bridging the Gaps: Unraveling the Impact of Snow Properties on Brine Wicking and Runoff by Anton Komarov, Clement Soriot, Robbie Mallett, Rosemary Willatt, John Yackel, Matthew Sturm, Julienne Stroeve

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Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum—the study protocol by Irina Chmelova, Irina Chmelova, Dalibor Pastucha, Dalibor Pastucha, Tomas Hudecek, Zdenek Guran, Zdenek Guran, Sona Ciecotkova, Lubomír Martínek, Jana Zubikova, Alena Matlova, Jakub Dolezel, Dana Salounova, Jakub Chmelo

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Homosexual Pairing within a Swarm-Based Mating System: The Case of the Chironomid Midge by Athol J. McLachlan

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Research priorities for autosomal dominant polycystic kidney disease: a UK priority setting partnership by Tess Harris, Albert Ong, Paul J D Winyard, Richard N Sandford, Maryrose Tarpey, Hannah R Bridges, Wendy D Brown, Natasha L O’Brien, Ann C Daly, Bharat K Jindal, Gillian S Mundy, Albert J Power, John Sayer, Roslyn J Simms, Patricia D Wilson

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Economic burden of musculoskeletal disorders in Tanzania: results from a community-based survey by Stefan Siebert, Emma McIntosh, Manuela Deidda, Richard Walker, Ping-Hsuan Hsieh, Blandina Mmbaga, Clive Kelly, Kajiru Kilonzo, Eleanor Grieve, Elizabeth F Msoka, Kiula Kiula, Nateiya Yongolo, Sanjura Mandela Biswaro, Stefanie Krauth, Jo Halliday

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Assessing the suitability of sites near Pine Island Glacier for subglacial bedrock drilling aimed at detecting Holocene retreat–readvance by J. S. Johnson, J. Woodward, I. Nesbitt, K. Winter, S. Campbell, K. A. Nichols, R. A. Venturelli, S. Braddock, B. M. Goehring, B. Hall, D. H. Rood, G. Balco, G. Balco

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Invisible Men: Unlocking Compassion and Understanding the Needs of Older Men Behind Bars by Louise Ridley, Kathryn E. Waldegrave

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Multiangle Social Network Recommendation Algorithms and Similarity Network Evaluation by Jinyu Hu, Zhiwei Gao, Weisen Pan

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Editorial: Aspiration management and rehabilitation by Phyllis M. Palmer, Paula Leslie, Paula Leslie

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Self‐compensation of DC–DC converters under peak current mode control by A. El Aroudi, K. Mandal, D. Giaouris, S. Banerjee

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Modules Identification in Gene Positive Networks of Hepatocellular Carcinoma Using Pearson Agglomerative Method and Pearson Cohesion Coupling Modularity by Jinyu Hu, Zhiwei Gao

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An Alternative Sensitivity Approach for Longitudinal Analysis with Dropout by Amal Almohisen, Robin Henderson, Arwa M. Alshingiti

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Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity by Brian M Ortmann

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Single-Event-Upset Sensitivity Analysis on Low-Swing Drivers by Nor Muzlifah Mahyuddin, Gordon Russell

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Statistics of Conditional Fluid Velocity in the Corrugated Flamelets Regime of Turbulent Premixed Combustion: A Direct Numerical Simulation Study by Nilanjan Chakraborty, Andrei N. Lipatnikov

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