Oral Health Knowledge, Attitudes, and Practices of Individuals with Diabetes Mellitus in the Sultanate of Oman by Noora Al Shihi, Abdulhakeem Al Rawahi, Raya Al Jahdhami, Rayyan Al Riyami, Abdulaziz Al Murazza, Noor Al Busaidi, Fatma Al Riyami, Suad Al Salti

“…In terms of practices, more than half (54.74.8%) routinely brushed their teeth twice a day. However, only 14.6% and 12.6% regularly flossed and used mouthwash, respectively. …”
Get full text

Real-World Efficacy and Safety of Avelumab Plus Axitinib in Metastatic Renal Cell Carcinoma: Results from the Ambispective RAVE-Renal Study by Ilya Tsimafeyeu, Vyacheslav Chubenko, Olga Baklanova, Alexey Kalpinskiy, Sufia Safina, Andrei Lebedinets, Vladislav Petkau, Elvira Parsadanova, Maria Turganova, Aleksei Shkurat, Natalia Tovbik, Elena Tkacheva, Yulia Anzhiganova, Olga Novikova, Varvara Bragina, Ruslan Zukov, Rashida Orlova

“…Patients received avelumab (800 mg intravenously every 2 weeks) plus axitinib (5 mg orally twice daily). The primary endpoints were median progression-free survival (PFS) and objective response rate (ORR). …”
Get full text

Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials by Hillary Norton, Paula Sliwinska-Stanczyk, Tomas Hala, Bassel El-Zorkany, Lori Stockert, Rajiv Mundayat, Lisy Wang, Christopher T. Ritchlin

“…Methods Data were pooled from phase 2/3 trials; analyses included patients with active AS randomized (1:1) to tofacitinib 5 mg twice daily or placebo, who were stratified by baseline BMI into < 25, ≥ 25 to < 30, and ≥ 30 kg/m2 categories. …”
Get full text

Tobacco Treatment Disparities Among California Medicaid Members With and Without Chronic Disease Who Smoke by Nan Wang, PhD, Melanie S. Dove, ScD, Cindy V. Valencia, PhD, Elisa K. Tong, MD

“…In adjusted models, smokers with chronic disease were almost twice as likely to receive advice (OR=1.97, 95% CI=1.39, 2.78) and 1.5 times as likely to receive assistance (OR=1.50, 95% CI=0.94, 2.38) as those without chronic disease, but the latter was not statistically significant. …”
Get full text

Healthcare practitioners as accomplices: a qualitative study of gender affirmation in a context of ambiguous regulation in Indonesia by Benjamin Hegarty, Alegra Wolter, Amalia Puri Handayani, Kevin Marian, Jamee Newland, Dede Oetomo, Ignatius Praptoraharjo, Angela Kelly-Hanku

“…Methods In this qualitative study, we drew on a participatory methodology to conduct 46 semi-structured interviews between October and December 2023, with trans people (10 trans feminine people and 10 trans masculine people, each interviewed twice) and key informants (three healthcare providers and three lawyers and paralegals). …”
Get full text

In vivo pharmacokinetic and pharmacodynamic study and cutoff of florfenicol against Riemerella anatipestifer in ducks by Hui-Lin Zhang, Fa-Lei Li, Hui-Yang Chen, Ding-Mei Qin, Shu-Jun Sun, Meng-Meng Zhang, Huan-Zhong Ding, Yong Liu

“…For PD analysis, the infected ducks were administered FF via the i.m. route at doses of 5–80 mg/kg body weight, using 2 dosing regimens involving the administration of FF either once or twice over 24 h. The bacteria were counted 24 h after drug administration. …”
Get full text

A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…The forage was just ryegrass at the re-blossoming stage, cut twice a day to avoid any fermentation, and immediately put in the mixing wagon, with no storage, and administered to animals. …”
Get full text

Remediating cognitive inflexibility in obsessive compulsive disorder and anorexia nervosa neither moderates nor mediates treatment effects: an exploratory study by Boris van Passel, Boris van Passel, Unna N. Danner, Unna N. Danner, Alexandra E. Dingemans, Theo G. Broekman, Lot C. Sternheim, Lot C. Sternheim, Eni S. Becker, Annemarie A. van Elburg, Annemarie A. van Elburg, Eric F. van Furth, Eric F. van Furth, Gert-Jan Hendriks, Gert-Jan Hendriks, Gert-Jan Hendriks, Daniëlle C. Cath, Daniëlle C. Cath

“…Participants underwent 10 twice-weekly sessions of either CRT or a non-specific active control intervention (specialized attention therapy; SAT), followed by treatment as usual. …”
Get full text

Traditional Chinese medicine manual therapy for adolescent idiopathic scoliosis: a case report by Bowen Zhu, Miaoxiu Li, Jun Ren, Tianxiang He, Xin Zhou, Shoujian Wang, Lingjun Kong, Min Fang, Min Fang

“…The patient initially recovered from centralized LBP with repeated TCMMT twice per week for 1 month. Subsequently, the frequency of TCMMT treatment was changed to 1–2 sessions weekly for 6 months. …”
Get full text

Longitudinal Screening for Diabetic Retinopathy in a Nationwide Screening Program: Comparing Deep Learning and Human Graders by Jirawut Limwattanayingyong, Variya Nganthavee, Kasem Seresirikachorn, Tassapol Singalavanija, Ngamphol Soonthornworasiri, Varis Ruamviboonsuk, Chetan Rao, Rajiv Raman, Andrzej Grzybowski, Mike Schaekermann, Lily H. Peng, Dale R. Webster, Christopher Semturs, Jonathan Krause, Rory Sayres, Fred Hersch, Richa Tiwari, Yun Liu, Paisan Ruamviboonsuk

“…We randomly selected patients with diabetes screened twice, two years apart within a nationwide screening program. …”
Get full text

Randomized trial of influence of vitamin D on the prevention and improvement of symptomatic COVID-19 by Huan Wang, Liyuan Tao, Liyan Cui, Yahong Chen, Dongyang Liu, Lixiang Xue, Yuping Yang, Yang Lv, Fuchun Zhang, Tiancheng Wang, Xiaoxiao Wang, Wanqiong Yuan, Hao Liu, Jie Huang, Yanfang Jiang, Na Liu, Lijuan Yang, Yunjing Hu, Yanfang Li, Yuling Gao, Haiyan Li, Baohua Li, Chunli Song

“…Subjects recorded PCR or antigen tests and the symptoms of COVID-19 twice a week during the follow-up visit. The concentration of serum 25-hydroxyvitamin D (25(OH)D), C-reaction protein (CRP), complement component C1q and inflammatory cytokines were measured. …”
Get full text

Synchronized autologous T-cell immunotherapy with hyperthermia to previously heavy treated advanced renal cell carcinoma by Jun Ren, Congcong Li, Dazhao Xu, Kun Wan, Chuxiong Zeng, Lina Hu, Xianzhi Guo, Feifei Huo, Xiumei Rong, Xinna Zhou, Tiecheng Wu, Xiaoli Wang, Bo Sun, JingJing Lou, Amy Hobeika, Michael A. Morse, Herbert Kim Lyerly

“…The peripheral blood apheresis was completed to produce ACT in vitro periodically .The nonimplantable in-depth hyperthermia device where the intratumor temperature could reach 42.5 C was performed for the average of 45 min, twice per week. One cycle ACT constituted three infusions of RetroNectin activated killer (RAK)cells at each 28 days interval. …”
Get full text

Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmona... by Huang SY, Hsieh PC, Huang KL, Yang MC, Jao LY, Tzeng IS, Lan CC, Wu YK

“…PR involved 12 weeks of hospital-based endurance training on a bike, performed twice a week. Participants were assessed before and after PR using spirometry, respiratory muscle strength measurements, CPET, and HRQL evaluation with the St. …”
Get full text

Addition of Vitamin C on Diet to Improve Immunity on Tiger Grouper, Epinephelus fuscoguttatus to Infection Viral Nervous Necrosis by F. Johnny, K. Mahardika, I.N.A. Giri, D. Roza

“…Experimental diets were prepared as dry pellet using freeze dryer Fish fed experimental diets twice everyday during 60 day. After 20, 40, and 60 days after treatment test to challange with VNN. …”
Get full text

Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…A safety run-in cohort was planned with the first 6 patients receiving oral donafenib 200 mg twice daily and intravenous sintilimab 200 mg once every 3 weeks. …”
Get full text

Dietary Alpha-Lipoic Acid Alleviated Hepatic Glycogen Deposition and Improved Inflammation Response of Largemouth Bass (<i>Micropterus salmoides</i>) Fed on High Dietary Carbohydra... by Zishuo Fang, Xianwei Pan, Ye Gong, Nihe Zhang, Shiwen Chen, Ning Liu, Naisong Chen, Songlin Li

“…Three iso-nitrogenous and iso-lipidic diets supplementing with 0 g/kg, 0.5 g/kg and 1 g/kg LA (LA0, LA500, LA1000) were designed to feed juvenile largemouth bass on a satiation diet twice daily for eight weeks with each diet feeding to triplicate groups. …”
Get full text

A Case of Cardiac Arrest during C1 Laminectomy for Irreducible Atlantoaxial Subluxation by Yosuke Shibao, Masao Koda, Keita Nakayama, Tomoyuki Asada, Kosuke Sato, Mamoru Kono, Fumihiko Eto, Kentaro Mataki, Hiroshi Kumagai, Katsuya Nagashima, Kousei Miura, Hiroshi Noguchi, Hiroshi Takahashi, Toru Funayama, Tetsuya Abe, Masashi Yamazaki

“…Cardiac arrest occurred twice during the C1 laminectomy and occipito-cervical fusion (Occ-C3), and ROSC occurred without any treatment. …”
Get full text

Glycogen and proximate content of white shrimp fed on different carbohydrate level and feeding frequency by , Zainuddin, , Haryati, Siti Aslamyah

“…Treatments were factor A, carbohydrate level in feed respectively A1 (30%), A2 (37%), A3 (44%), A4 (50%), and factor B daily feeding frequency respectively B1 (twice), B2 (four times), and B3 (six times) respectively. …”
Get full text

Mental health in the COVID-19 pandemic: A longitudinal analysis of the CLoCk cohort study. by Laura Panagi, Simon R White, Snehal M Pinto Pereira, Manjula D Nugawela, Isobel Heyman, Kishan Sharma, Terence Stephenson, Trudie Chalder, Natalia K Rojas, Emma Dalrymple, Kelsey McOwat, Ruth Simmons, Olivia Swann, CLoCk Consortium, Tamsin Ford, Roz Shafran

“…They completed the Strengths and Difficulties Questionnaire (SDQ) at least twice over a 12-month follow-up period. Overall, 8,518 of 17,918 (47.5%) CYP who returned their first SDQ at 3 or 6 months post-testing were included in the analytical sample. …”
Get full text

Antibiotic-mediated dysbiosis leads to activation of inflammatory pathways by Jemma J. Taitz, Jemma J. Taitz, Jian Tan, Jian Tan, Duan Ni, Duan Ni, Camille Potier-Villette, Camille Potier-Villette, Georges Grau, Georges Grau, Ralph Nanan, Ralph Nanan, Ralph Nanan, Laurence Macia, Laurence Macia, Laurence Macia

“…While the impact of specific metabolites or taxa on host cells is well-documented, the broader impact of a disrupted microbiota on immune homeostasis is less understood, which is particularly important in the context of the increasing overuse of antibiotics.MethodsFemale C57BL/6 mice were gavaged twice daily for four weeks with Vancomycin, Polymyxin B, or PBS (control). …”
Get full text