Effects of dietary selenium nanoparticles, selenomethionine and sodium selenite on growth performance, levels of thyroid hormones and antioxidant status of rainbow trout, Oncorhync... by Fardin Shaluei, Somayeh Hadadi, Shafigh Shafiei, Hossein Rahimi, Mehrdad Fattollahi

“…Fish with an average weight of 29.25 ± 1.70 g were fed with experimental diets for 8 weeks. The fish were fed twice a day (at 9:00 AM and 2:00 PM) at the rate of 4% of their biomass.Results and discussion: The results showed that selenium nanoparticles had no significant effect on growth indices compared to organic and inorganic forms (p<0.05). …”
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Invertebrates of Siberia as a promising source of animal protein for innovative feed and food production. 6. Potential of nutrient accumulation in biomass via feed enrichment by Sergei E. Tshernyshev, Andrei S. Babenko, Irina B. Babkina, Ruslan T-O. Baghirov, Vera P. Modyaeva, Margarita D. Morozova, Ksenia E. Skriptcova, Elena Yu. Subbotina, Mikhail V. Shcherbakov, Anastasia V. Simakova

“…The addition of nutrients (substrate with a double dose of vitamins B7 and C, a mineral complex additive, fat-soluble vitamins, and B-complex vitamins) increased the content of fats, proteins, and carbohydrates in insects, as well as ash content in snails and worms. Insects are twice as caloric as snails and worms, and the caloric content of insects increases with the addition of nutrients, while that of snails and worms remains unchanged. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…We aim to explore the possible correlations between gut microbiota (GM) compositions and cardiometabolic (CM) disorder in MTX-triggered cardiotoxicity mice.Methods: MTX cumulative dose of 6 mg/kg was administered to healthy Kunming male mice to trigger cardiotoxicity, with 1 mg/kg twice weekly for a duration of 3 weeks. Plasma CK-MB and LDH levels were determined, and the heart tissue histopathology was assessed, followed by utilizing an integrated liquid chromatography-mass spectrometry (LC-MS)-based heart metabolomics study alongside the 16S ribosomal RNA (rRNA) sequencing method to assess MTX impact on GM and CM profiles in mice, establishing associations between GM and CM profiles through the Pearson correlation coefficient calculation.Results: MTX caused CK-MB and LDH level elevations and cardiotoxicity in our mouse model. …”
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Antidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients by Genet Alem Geberemeskel, Yared Godefa Debebe, Nigisty Abraha Nguse

“…They were grouped into two groups: the treatment group (n=57) consumed 25 g Trigonella foenum-graecum seed powder solution orally twice a day for one month and the second group is the control (n=57) which receives metformin. …”
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Addressing the specificities of contusion cataract surgery in adults by N.V. Kutukova, A. Yu. Kutukov, V.V. Brzheskiy

“…The total rate of zonular insufficiency in the study group was twice as much as in the control group. Additional devices (i.e., iris and capsular retractors, capsular tension rings etc.) were used in 46% of study group patients and 20% of control group patients. …”
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Feasibility of teleyoga for people with post COVID-19 condition– a mixed method design by Marie Lundberg, Leonie Klompstra, Lotti Orwelius, Mirjam Schimanke, Cecilia Olsson, Anna Strömberg

“…The intervention included standardised live-streamed teleyoga sessions twice/week for 7 weeks and individual yoga using a digital application during 12 weeks. …”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…The IMT group received training twice daily, 5 days a week, for three consecutive weeks. …”
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Sociodemographic and clinical factors associated with early childhood caries in Peruvian pre-schoolers by Daniel José Blanco-Victorio, Nieves Asteria López-Luján, Walter Bernaola-Silva, Luis Antonio Vicuña-Huaqui, Rocio Cacñahuaray-Palomino, Julissa Sarai Diaz-Campos, Yeni Araceli Anicama-Barrios, Zenaida Rojas-Apaza, Sara Castañeda-Sarmiento, Evelyn Alvarez Vidigal, Roxana Patricia López-Ramos

“…Mothers or caregivers reported brushing their children’s teeth twice daily (56.99%) and giving sweets one to two times daily (79.03%). …”
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Identifying the Dimensions and Consequences of Digital Customer Experience: A Phenomenological Study by Fatemeh Eslahi, Seyed Mohammad Reza Mirahmadi, Mojtaba Aghajani

“…The statistical population consists of individuals who engage in internet purchasing on websites at least twice a month, with a monthly purchasing amount exceeding 500 thousand Tomans. …”
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L’entrepreneuriat touristique local : une opportunité d’inversion du processus de marginalisation d’un centre historique ? Une analyse dans la médina de Fès au Maroc by Merryl Joly

“…Field surveys were conducted in June-July 2018 and December 2019, supplemented by observations conducted as a resident in the medina of Fez between 2016 and 2020, and again twice during the health crisis. A total of 20 interviews were conducted: ten with modest families who have gradually converted their homes from income derived from low-skilled jobs in different sectors (tourism, crafts, catering); two with disadvantaged households who have benefited from government assistance through the "Ziyarates Fez" program; and three with tourism entrepreneurs who are also large property owners. …”
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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

“…Methods Patients with RA in ORAL Surveillance (NCT02092467), who were aged ≥ 50 years with ≥ 1 additional CV risk factor, received tofacitinib 5 or 10 mg twice daily or TNFi; 45.9% were from either Poland or North America. …”
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Growth performance of African catfish Clarias gariepinus cultured in biofloc system at high stocking density by Petrus Hary Tjahja Soedibya, Taufik Budhi Pramono, Emyliana Listiowati

“…During rearing period, fish were given the artificial feed with protein contents of 28.75% with the frequency of twice a day, as much as 3% of the body weight. The results showed that different treatment of high stocking density in the biofloc system had a significant effect on the absolute growth rate, lipid retention and energy retention (P<0.05) but not significant effect on daily growth rate. …”
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Evaluation of Biologics ACE2/Ang(1–7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies by Henry Daniell, Geetanjali Wakade, Smruti K. Nair, Rahul Singh, Steven A. Emanuel, Barry Brock, Kenneth B. Margulies

“…Oral gavage was performed twice daily for 14 days (the dosing phase) followed by the recovery phase (35 days). …”
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Sequential Docetaxel in ≥7 Cycles Followed by Cabazitaxel Improves Oncological Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer by Seiichi Kato, Manabu Takai, Koji Iinuma, Shota Fujimoto, Masahiro Nakano, Takashi Ishida, Masahiro Uno, Masayoshi Tamaki, Mitsuhiro Taniguchi, Hisao Komeda, Yoshito Takahashi, Takuya Koie

“…Androgen-deprivation therapy and prednisolone 5 mg (twice daily) were administered throughout both regimens. …”
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A family with normal sperm motility carrying a sY86 deletion in AZFa region and partial deletion in AZFc region by Yuhong Zhao, Weiwei Zhi, Weiwei Zhi, Dongsheng Xiong, Dongsheng Xiong, Ningjing Li, Xinrong Du, Jiuzhi Zeng, Jiuzhi Zeng, Guohui Zhang, Guohui Zhang, Weixin Liu, Weixin Liu

“…Notably, although the son’s sperm motility parameters showed no significant abnormalities, there was a history of failed pregnancies for twice, with sperm exhibiting a high rate of head defect.DiscussionGiven the complexities of the reproductive phenotype following AZF region deletions, additional extended genetic testing is necessary when partial deletions in the AZF region are detected, thus providing more accurate predictions of the spermatogenesis in patient. …”
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Efficacy and safety of interferon-alpha 1b injection into the intervertebral foramen with ultrasonic guidance in patients with postherpetic neuralgia: study protocol for a randomiz... by Hui-Min Hu, Hui-Min Hu, Wen-Hui Liu, Wen-Hui Liu, Chen Li, Chen Li, Qing Shi, Qing Shi, Chun-Hua Liu, Chun-Hua Liu, An-Xiang Liu, An-Xiang Liu, Yi-Fan Li, Yi Zhang, Peng Mao, Bi-Fa Fan

“…Both groups will also receive oral pregabalin 150 mg twice daily and lidocaine injection into the intervertebral foramen as conventional therapy. …”
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Effects of Ivabradine on Residual Myocardial Ischemia after PCI Evaluated by Stress Echocardiography by Simone Calcagno, Fabio Infusino, Olga Dettori, Temistocle Taccheri, Pasqualina Bruno, Viviana Maestrini, Gennaro Sardella, Massimo Mancone, Francesco Fedele

“…Twenty-eight consecutive patients with residual angina after PCI were randomized to ivabradine 5 mg twice/day (IG) or standard therapy (CG). All patients performed a stress echocardiography at the enrollment and after 30 days. …”
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DYNAMICS OF MISCARRIAGE AMONG THE FEMALE POPULATION OF FERTILE AGE IN UKRAINE AND IN LVIV REGION IN 2014-2021 by Nataliia Timchenko, Taras Gutor

“…The rates of spontaneous abortions per 1,000 women of fertile age in Lviv region were twice as low as in Ukraine. Over the analyzed 8-year period, the share of premature children among all live births increased from 4.68% to 5.68% in Ukraine, and from 4.18% to 5.65% in Lviv region, respectively; these indicators in Lviv region were smaller compared to the indicators in Ukraine. …”
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Contezolid Harbored Equivalent Efficacy to Linezolid in Tuberculosis Treatment in a Prospective and Randomized Early Bactericidal Activity Study by Jiang G, Liu R, Xue Y, Ge Q, Nie L, Lv Z, Kong Z, Shi J, Chen H, Li H, Wu X, Xie L, Song Y, Huang H, Gao M

“…In this study, we evaluated the early bactericidal activity (EBA) of CZD compared to LZD, with LZD serving as a control.Methods: Naive, smear-positive pulmonary TB patients were enrolled and randomly assigned to receive either a 14-day monotherapy regimen of 600 mg LZD once daily (QD) or 800 mg CZD twice daily (BID). Sputum samples were collected daily starting one day before treatment initiation and continuing throughout the treatment period. …”
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An Improved Method for Extracting Rat Cerebrospinal Fluid with Repeatable Large-Scale Collection by Limei Wang, Wei Yang, Yanhong Ran, Hui Song, Xinxin Yan, Jianmin Guo

“…A 26G scalp needle, combined with a 1 mL syringe, was used to puncture the atlanto-occipital membrane and collect approximately 170 μL of CSF. CSF was collected twice within 14 days. During the study, animals were monitored daily for food intake, body weight, and hematological parameters, and at the end of the study, histopathological examination was performed. …”
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