Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes by S. V. Michurina, I. Yu. Ishchenko, S. A. Arkhipov, M. A. Cherepanova, D. V. Vasendin, E. L. Zavjalov

“…The Bcl-2/Bad expression area ratio in 10-week-old animals was twice as high as in 18-week-old animals, which indicates the presence of conditions for blocking apoptosis in the liver of younger db/db mice. …”
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Heme-Iron OptiFer® in the Treatment of Iron Deficiency Anemia During Pregnancy by Ibrahim A. Abdelazim, Mohannad AbuFaza, Soud M. Al-Ajmi, Osama O. Amer, Svetlana Shikanova, Bakyt Karimova

“…Women in the heme-iron OptiFer® group received OptiFer® tablets twice daily for ≥3 months then once daily as a maintenance dose. …”
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Satisfaction, effectiveness, and usability of telerehabilitation for Parkinson's disease patients by Shohei Okusa, Hiroki Saegusa, Kazuya Miyakawa, Yuta Tsutsumi, Sae Ishida, Kyoko Nishikata, Tomonori Nukariya, Toshiki Tezuka, Yoshihiro Nihei, Yasuhiro Kitagawa, Shin-ichiro Kubo, Norihiro Suzuki, Jin Nakahara, Morinobu Seki

“…Methods: The telerehabilitation was conducted twice a week via a Zoom meeting platform, using pre-recorded rehabilitation contents shared during the sessions. …”
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Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson’s Disease: A Pilot Randomized Controlled Trial by Hanna Johansson, Malin Freidle, Urban Ekman, Ellika Schalling, Breiffni Leavy, Per Svenningsson, Maria Hagströmer, Erika Franzén

“…Both groups received one-hour sessions twice weekly, plus home exercises weekly, for 10 weeks. …”
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Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Place... by Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Suzan M. M. Moursi, Najah M. Al-Baqami, Fawziah A. Al-Salmi, Mai S. Attia

“…The pregnant female rats were randomly divided into three groups: group 1 (normal pregnant group), group 2 (PE-induced group), injected subcutaneously with 75 mg L-NAME/kg bodyweight/day starting from day 9 to 20 of gestation, and group 3 (PE-induced group supplemented with apelin (PE + apelin)); PE induced as before and simultaneously subcutaneously injected with apelin-13 (6 × 10−8 mol/kg bodyweight/twice daily) beginning from day 6 to 20 of gestation. …”
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Neutrophil extracellular traps as an important part of the pathogenesis of chronic rhinosinusitis without polyps by Valery М. Svistushkin, Galina N. Nikiforova, Boris V. Pinegin, Nina V. Vorobjeva, Artem S. Dekhanov, Yulia A. Dagil, Anna R. Mironova

“…In patients who received azoximer bromide, the material was taken twice – before the start of treatment and 10 days after the course of treatment. …”
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The Effect of Goat Grazing on the Biodiversity of Pannonian Dry Grassland by Karoly Penksza, Ferenc Pajor, Andrea Kevi, Zsombor Wagenhoffer, Laszló Sipos, Eszter Salata-Falusi, Peter Penksza, Peter Poti, Jozsef Berke, Denes Salata, Marta Bajnok, Szilard Szentes

“…The species richness of C2 was twice that of the mown field (N2). Based on the present study, a combination of light grazing pressure and mowing is the most suitable approach for managing and economically utilizing these grasslands.…”
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Effect of Swimming on Gut Microbiota and Inflammation in Colorectal Cancer Cells Transplanted Mice by LI Jiapeng, XIE Qiurong, WEN Ying, CHEN Haichun, PENG Jun, SHEN Aling

“…The mice in the swimming group were subjected to physical training of swimming for 30 minutes each time and twice per day, 6 days per week for 3 weeks in total. …”
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Adaptation of global primary production model to the Greenland Sea conditions: parameterization and monitoring for 1998-2022 by Aleksandra Cherkasheva, Rustam Manurov, Piotr Kowalczuk, Alexandra N. Loginova, Monika Zabłocka, Astrid Bracher, Astrid Bracher

“…An example is the difference in net primary production modelling estimates, which differ twice globally and fifty times when only the Arctic region is considered. …”
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Folic acid supplementation during preconception period in sub-Saharan African countries: A systematic review and meta-analysis. by Mekuriaw Nibret Aweke, Elsa Awoke Fentie, Muluken Chanie Agimas, Lemlem Daniel Baffa, Ever Siyoum Shewarega, Aysheshim Kassahun Belew, Esmael Ali Muhammad, Berhanu Mengistu

“…The prevalence is about twice as common in low- and middle-income countries and more prevalent in sub-Saharan Africa. …”
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Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma: A randomized, double-blind, placebo-controlled trial by Meiyu Lyu, Yi Yang, Jinlian Liu, Wenting Fei, Min Fu, Yunting Hong, Hongguo Rong, Chun Wang, Linyuan Wang, Jianjun Zhang

“…A total of 110 female patients with melasma linked to kidney deficiency and blood stasis were enrolled and treated with either LDBG or a placebo twice daily for 60 days. Efficacy was assessed through measures such as the total melasma area, reduced melasma area, reduction rate of melasma area, melasma color score, Melasma Area and Severity Index (MASI) score, and traditional Chinese medicine (TCM) symptom score scale. …”
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Effect of COVID-19 Lockdown on Alcohol Consumption Among the Youths in Kampala, Uganda. A Cross-Sectional Study by Namiiro AM, Audo R, Nannungi CD, Pitua I, Kiberu D, Talemwa P, Mujuni E, Lwesabula A, Ageimo P, Khaukha AZ, Kuol MJ, Egaru L, Koire M, Ssewante N

“…At least 42.5% of the participants reported alcohol consumption during the lockdown. Males consumed twice as much alcohol as females. Generally, the level of alcohol consumption decreased during the COVID-19 pandemic as the percentage of participants consuming alcohol dropped from 47.5% to 42.8%. …”
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Effects of nintedanib on circulating biomarkers of idiopathic pulmonary fibrosis by R. Gisli Jenkins, Vincent Cottin, Yasuhiko Nishioka, Imre Noth, Eric S. White, Carina Ittrich, Claudia Diefenbach, Klaus B. Rohr, Moisés Selman, Toby M. Maher

“…Methods Subjects with IPF were randomised 1:2 to receive nintedanib 150 mg twice daily or placebo for 12 weeks, after which all patients received open-label nintedanib for 40 weeks. …”
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Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation by Seiki Tajima, Shigeyuki Yamamoto, Masaaki Tanaka, Yosky Kataoka, Masao Iwase, Etsuji Yoshikawa, Hiroyuki Okada, Hirotaka Onoe, Hideo Tsukada, Hirohiko Kuratsune, Yasuomi Ouchi, Yasuyoshi Watanabe

“…We performed H2O  15 positron emission tomography scans to indicate neural activations while subjects were performing 35-min fatigue-inducing task trials twice. During the positron emission tomography experiment, subjects performed advanced trail-making tests, touching the target circles in sequence located on the display of a touch-panel screen. …”
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Effects of Providing Enrichment to Broilers in an Animal Welfare Environment on Productivity, Litter Moisture, Gas Concentration (CO₂ and NH₃), Animal Welfare... by Chan-Ho Kim, Woo-Do Lee, Ji-Seon Son, Jung-Hwan Jeon, Se-Jin Lim, Su-Mi Kim

“…Analysis of all items was conducted twice, on the 19th and 27th, taking into account the farm’s feed change date and slaughter schedule. …”
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The epidemiology and unmet need of migraine in five european countries: results from the national health and wellness survey by Gianluca Coppola, Joshua D. Brown, Amanda R. Mercadante, Sheila Drakeley, Nikoletta Sternbach, Aaron Jenkins, Karin Hygge Blakeman, Astrid Gendolla

“…Migraine prevalence was highest in the age group of 30–39 years, and females had nearly twice the prevalence compared to males. About 56% of respondents reported disability due to migraines, with highest percentage reported in Germany (66.0%). …”
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Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 by Tayfun VURAL, Burak BAYRAKTAR, Suna YILDIRIM KARACA, Ozan ODABAS, Nisel YILMAZ, Pınar SAMLIOGLU, Mehmet OZEREN

“…The rate of primary cesarean section was more than twice in the symptomatic group (51.2%) than that of the asymptomatic group (20%) (p=0.019). …”
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Bibliotherapy Services in Public Libraries: the Case of Lithuania by Jurgita Girčienė, Miglė Damijonaitytė

“…Out of them, slightly more than twice (both qualitatively and quantitatively) of services are attributable to passive bibliotherapy, exclusively covering an intrapersonal level of communication, based on recommendations of books to be read, which is traditionally more characteristic of these institutions, rather than those to be associated with its active variety, which includes an individual interaction of a reader with a librarian inspired by the read book, or a group one - with the members of the book club led by them that integrates an interpersonal level of communication as well. …”
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Does binge drinking between the age of 18 and 25 years predict alcohol dependence in adulthood? A retrospective case–control study in France by Marie-Pierre Tavolacci, Joel Ladner, Pierre Déchelotte, Quentin Berthon, Damiano Cerasuolo, Alexandre Baguet

“…Frequency of binge drinking between 18 and 25 years was categorised as frequent if more than twice a month, occasional if once a month and never if no binge drinking.Results 166 adults between 25 and 45 years were included: 83 were alcohol-dependent and 83 were non-alcohol-dependent. …”
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Effect of L-carnitine on lipid biomarkers of oxidative stress in chronic hemodialysis patients: a randomized controlled trial by Shokoh Shayanpour, Seyyed Seyfollah Beladi Mousavi, Hossain Karimpourian, Khojasteh Hoseinynejad, Kambiz Ahmadi Angali

“…L-carnitine tablets (250 mg/T) dissolved in 30 mL water (25 mg/kg) were administered orally twice daily before meals for a period of 3 months in the intervention group (n=44). …”
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