Addition of PARP1-inhibition enhances chemoradiotherapy and thermoradiotherapy when treating cervical cancer in an in vivo mouse model by Marloes IJff, Xionge Mei, Enzo M. Scutigliani, Hans M. Rodermond, Gregor G. W. van Bochove, Przemek M. Krawczyk, Nicolaas A. P. Franken, Lukas J. A. Stalpers, Johannes Crezee, Arlene L. Oei

“…Five cycles of treatment were applied with the following doses per cycle: irradiation 3 Gy, hyperthermia 1 h at 42 °C, cisplatin at 2 mg/kg, and twice PARP1-i at 50 mg/kg.Results: Quadruple treatment, combining radiotherapy, hyperthermia, cisplatin and PARP1-i, was very effective but also lead to severe side effects causing severe weight loss and death. …”
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Efektifitas Edukasi Tentang Jajanan Sehat Terhadap Peningkatan Pengetahuan dan Sikap Siswa Overweight by Firnaliza Rizona, Karolin Adhisty, Fuji Rahmawati

“…Sample election used purposive sampling and FGD process conducted twice meeting. Data collected by using quessioner on pretest and posttest. …”
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Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer’s Disease by Anastasia Nousia, Vasileios Siokas, Eleni Aretouli, Lambros Messinis, Athina-Maria Aloizou, Maria Martzoukou, Maria Karala, Charalampos Koumpoulis, Grigorios Nasios, Efthimios Dardiotis

“…The duration of the MCT intervention program was 15 weeks, and it was administered twice a week. Each session lasted for approximately one hour. …”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

“…In addition, we recruited 12 healthy people and clinically stable patients with PAH (n = 45) as controls who had 2 blood samples collected twice within 14 days. We generated platelet-free plasma and measured D-dimer, angiopoietin-2, thrombin time, soluble P-selectin, von Willebrand factor, and vascular endothelial growth factor. …”
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Lymphoadenopathies caused by Bartonella henselae by V.S. Zhukovskiy, O.V. Prokopiv, I.R. Trutyak, M.V. Pankiv

“…In the second case, a subfebrile body temperature, a painful lymph node in the right axillary area for 3 weeks were the reason to perform an invasive surgery twice for diagnosed bacterial process of unknown etiology. …”
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Postcholecystectomy syndrome: the modern approach: resolution of Advisory council by V. T. Ivashkin, A. V. Okhlobystin, D. S. Bordin, E. Ya. Seleznyova, Yu. A. Kucheryavy, Ye. V. Bystrovskaya, O. C. Vasnev, M. F. Osipenko, G. H. Musayev, Yu. O. Shulpekova

“…The total number of GSD patients increases every decade no less than twice. Cholecystectomy remains the basic method of surgical treatment of symptomatic GSD. …”
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Stellarator fusion systems enabled by arrays of planar coils by D.A. Gates, S. Aslam, B. Berzin, P. Bonofiglo, A. Cote, D.W. Dudt, E. Flom, D. Fort, A. Koen, T.G. Kruger, S.T.A. Kumar, M.F. Martin, A. Ottaviano, S. Pasmann, P.K. Romano, C.P.S. Swanson, L. Tang, E. Winkler, R. Wu

“…The second near-term use case considered is a deuterium–tritium stellarator fusion pilot plant, called Helios, that would be approximately twice the linear dimension of the Eos design.…”
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Tropical Cyclone Size Prediction and Development of An Error Correction Method by Guo Ruichen, Xu Jing, Wang Yuqing

“…In 47% of samples, errors in the radius of maximum wind (RMW) could be more than twice as large as observations, while R33 and R26 are also overestimated. …”
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High levels of type II Fusarium head blight resistance conferred in wheat by combining wheat gene Fhb1 with Lophopyrum elongatum gene Fhb7The2 by Jan Dvorak, Karin R. Deal, Patrick E. McGuire, Emily J. Conley, James A. Anderson, George Fedak, Julia A. Malvick, Han Chen, Hans-Georg Müller

“…Spikes of these lines, parental cv Rollag and MN-Washburn, and those of disomic addition line 7E possessing Fhb7The2 plus controls were inoculated with Fusarium in a twice-replicated trial in controlled greenhouse environmental conditions. …”
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Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

“…For ten weeks, participants were randomized to receive either a placebo or 5 mg of melatonin twice a day. Baseline characteristics, dietary intake, physical activity, and anthropometric measurements were recorded. …”
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Assessing the cataract surgical rate and gender equity in cataract services in south-east Nigeria by Clare Gilbert, Onyinye Onyia, Ada Ejealor Aghaji, Christiana Ubaka, Eberechukwu Ogbeanu Achigbu, Ifeoma Lilian Ejiakor, Adaku I Mbatuegwu, Chiamaka J P Okeke, Barbara C Okoli, Emmanuel U Ogborogu, Kenneth C Dike, Florence U Nkwogu

“…Cataract surgery is a cost-effective treatment for cataracts. In Nigeria, twice as many women are cataract blind as men. Cataract surgical rate (CSR, the number of cataract operations per million population per year in a defined geographical location) is an output indicator of cataract surgical services. …”
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Transcranial photobiomodulation for reducing symptoms of autism spectrum disorder and modulating brain electrophysiology in children aged 2–7: an open label study by Yuli Fradkin, Joaquin A. Anguera, Alexander J. Simon, Luis De Taboada, Eugenia Steingold

“…We delivered non-invasively to all participants pulses of near-infrared light (wavelength 850 nm, pulse 40 Hz) to cortical nodes of Default Mode Network, Broca and Wernicke areas, and occipital lobe of the brain, twice weekly for 10 weeks. The tPBM was delivered using an investigational medical device designed for this purpose. …”
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Repetition of Prediabetes Enhances the Risk of Developing Diabetes by Yoshihiro Numata, Toshihide Ohya, Yasuhiko Nitta, Yumiko Yoshinaka, Azusa Shogakiuchi, Akihiro Toyota

“…In the group whose frequency of PD3 was two, the individuals who had repeated the status of PD3 twice then moved to the status other than PD3 showed smaller risk of DM than the others in the same group. …”
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Healthcare resource use of patients with transthyretin amyloid cardiomyopathy by Rosa Lauppe, Johan Liseth Hansen, Anna Fornwall, Katarina Johansson, Mark H. Rozenbaum, Anne Mette Strand, Merja Vakevainen, Johanna Kuusisto, Einar Gude, J. Gustav Smith, Finn Gustafsson

“…Conclusions Transthyretin amyloid cardiomyopathy imposes a high burden on healthcare systems with twice as many outpatient specialist visits and 50% more hospitalizations in the year after diagnosis compared with HF patients without ATTR‐CM. …”
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Case Report of Jingyun Platform's Cognitive Training on Cognitive Impairment with Aphasia by Yu ZHOU, Zhuoming CHEN, Hantian GUAN, Chaoping OUYANG

“…Each stage lasts for six weeks, 30 minutes at a time, twice a day. The total score of MoCA, subitem score in MoCA, the correct number of words in memory and delayed recall, total time of MoCA evaluation and time-consuming changes in memory were calculated.Results:Compared with before treatment, the memory and delayed recall in traditional cognitive training stage and Jingyun platform cognitive training stage were improved. …”
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The Optimum Dietary Phenylalanine Requirement of Hybrid Grouper (Epinephelusfuscoguttatus ♀ × Epinepheluslanceolatus ♂) Juveniles: Effects on Growth Performance, Gut Micromorpholog... by Pinxian Yang, Haijiao Wang, Lei Ma, Haoran Yin, Zhanying Zhu, Cong Liu, Wei Huang, Zhiyu Zhou, Xiaoyi Wu, Sehrish Taj

“…Triplicate tanks of juvenile fish (about 16.7 g/fish) were fed each experimental diet twice daily until apparent satiation. The results indicated that different dietary Phe levels significantly influenced weight gain percentage (WG), feed efficiency (FE), protein efficiency ratio (PER), as well as, productive protein value (PPV). …”
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Effects of dietary Chlorella ellipsoidea on growth performance, body composition, and hematology of stinging catfish, Heteropneustes fossilis by Alam Asraful, Bristy Fouzia Sultana, Amzad Hossain M., Rabiul Islam M., Fatema Umme Kaniz, Golam Rasul M.

“…Triplicate groups of fish were fed with each experimental diet to satiation twice daily for 10 weeks. At the end of the feeding trial, the weight gain (%) of the fish fed CE 5 and CE 7.5 was significantly (P < 0.05) higher than that of fish fed the control diet. …”
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Self-assessment of didactic performance of psychology and education professors in Mexico and Peru by Aldo Bazán-Ramírez, Walter Capa-Luque, Roberto Chávez-Nava, Mónica C. Dávila-Navarro, Homero Ango-Aguilar, Edmundo Hervias-Guerra, Catalina Bello-Vidal

“…Likewise, being an education teacher and a woman is more than twice as likely to have optimal teaching performance. …”
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Syntheses, structures and anticancer activities of CuII and ZnII complexes containing 1,1′-[(3-fluorophenyl)methylene]bis[3-(3-fluorophenyl)imidazo[1,5-a]pyridine] by Hai Le Thi Hong, Hau Nguyen Van, Duong Hoang Tuan, Hung Tran Quang, Tuan Dang Thanh, Luc Van Meervelt

“…Notably, the CuII complex displays excellent inhibitory activity against the MCF7 breast cancer cell line (IC50 = 27.99 µM), approximately twice as effective as cisplatin. Conversely, the ZnT4 complex shows greater efficacy against Hep-G2 and A549 lung cancer cell lines, with IC50 values between 18.93 and 24.83 µM. …”
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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Birds' glycolipid metabolism has garnered considerable attention due to their fasting blood glucose levels being nearly twice those of mammals. While skeletal muscle is the primary insulin-sensitive tissue in mammals, the effects of insulin on chicken skeletal muscle remain unclear. …”
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