Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes by Ying Tian, Jiawei Gong, Zhiyan He, Suwen Peng, Yuping Huan, Hongpeng Cao

“…At the same time of 40% calorie restriction, increasing dietary protein intake to twice the normal protein intake has a stronger effect on promoting hepatic triglyceride oxidation and reducing liver fat content in the male overweight and obese rats by increasing the levels of adiponectin and leptin in the blood, and can also significantly reduce the plasma cholesterol concentration in the female overweight and obese rats through inhibiting cholesterol synthesis most likely by increasing glucagon level in the blood.…”
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Sex-specific analysis of individual and ski geometry-related risk factors for ACL injuries in recreational alpine skiing: A case-control study by Gerhard Ruedl, Martin Faulhaber, Markus Posch

“… Introduction In recreational alpine skiing, female skiers experience knee injuries at twice the rate of male skiers, with the risk of anterior cruciate ligament (ACL) injuries being three times higher in women (Posch et al. 2021). …”
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A qualitative study exploring the acceptability of the TEXTPAD telehealth and virtual supervised exercise intervention and trial for patients with peripheral arterial disease livin... by Maddey Patterson, MPH, Letitia Sermin-Reed, MSc, James Prentis, MBBS, Arathi Radhakrishnan, MBBS, Eileen Kaner, PhD, Sandip Nandhra, MBBS, Maisie Rowland, BSc, Gabriel Cucato, PhD, Mackenzie Fong, PhD

“…The TEXTPAD pilot randomized controlled trial investigated the impact of the 12-week TEXTPAD intervention that involved weekly phone calls for behavioral counselling and twice-weekly virtual, supervised exercise sessions. …”
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Structural safety assessment procedure of plastic single-span greenhouses considering semi-rigid clamp joints by Byung-Hun Seo, Sangik Lee, Do-Kyung Kim, Jong-Hyuk Lee, Dong-Su Kim, Dong-Woo Kim, Yerim Jo, Won Choi

“…Loading test on two types of clamp joints revealed that SP (Steel-plate) joints exhibited more than twice the limit strength of SW (Steel-wire) joints. …”
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Effect of Body-Weight-Based Resistance Training on Balance Ability and Fear of Falling in Community-Dwelling Older Japanese Women by Zhenyue Liu, Shuji Sawada, Pengyu Deng, Hisashi Naito, Shuichi Machida

“…The LRT group participated in the exercise session twice weekly for 12 weeks, while the CON group maintained their daily routine. …”
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The evaluation of different levels diets protein for growth performance of Clarias sp. fry cultured in biofloc-based system by Noviati Rohmatul Khasanah, Nur Bambang Priyo Utomo, Mia Setiawati, Munti Yuhana

“…Feeding was conducted twice a day at 5% of the biomass weight. At the end of trial treatment (D) showed the highest survival rate (88.15±5.25%), the body lenght variance coefficient (9.58±0.51%) and protein retention (39.87±2.77%). …”
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Production of giant gourami Osphronemus goramy Lac. juvenile with different rate of water exchange by Tatag Budiardi, Rona Albrettico Nemanita Ginting, Yani Hadiroseyani

“…Water exchange was performed twice a day at a level depending on the treatment, namely 75% (50% at morning and 25% at evening), 100% (50% at morning and evening) and 125% (75% at morning and 50% at evening) of total water volume. …”
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Effectiveness of mDiabetes intervention in enhancing diabetes awareness and promoting healthy lifestyle changes among the general population in rural India by Padmaja Kumari Rani, Padmaja Kumari Rani, Padmaja Kumari Rani, Jachin David Williams, Nidhi Jaswal, Venkateswaralu Yandluri, Payal Sangani, Kavya Sanagavarapu, Ramya Natarajan, Sandhya Ramalingam, Nalini Saligram, Rohit C. Khanna, Rohit C. Khanna, Rohit C. Khanna, Rohit C. Khanna

“…Under this program, 56 diabetes prevention messages (twice a week) in local language) were disseminated among the participants via voice calls for a period of 6 months. …”
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Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study by David H Brewster, Victoria Cairnduff, Eila Watson, Amy Downing, Adam W Glaser, Penny Wright, William Cross, Conan Donnelly, Anna Gavin, Carol Rivas, Richard Wagland, Peter Selby, Luke Hounsome, Therese Kearney, Rebecca Mottram, Majorie Allen, Oonagh McSorley, Hugh Butcher, Paul Kind, James W H Catto, Dyfed Huws, Emma McNair, Lauren Matheson, Johana Nayoan, Mike Horton, Jessica Corner, Julia Verne

“…Eligible men will be identified and/or verified through cancer registration systems. Men will be surveyed twice, 12 months apart, to explore changes in outcomes over time. …”
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Abnormal Liver Tests during Hospitalization Predict Mortality in Patients with COVID-19: A Multicenter Study from South America by Domingo Balderramo, Angelo Z. Mattos, Victoria Mulqui, Talita Chiesa, Zuly Plácido-Damián, Jaysoom Abarca, Andrea Bolomo, Yanina Carlino, Isadora Z. Bombassaro, Denusa Wiltgen, Laura Tenorio Castillo, Karina Díaz, Johana Acuña, Estela Manero, Jhon Prieto, Enrique Carrera, Javier Díaz-Ferrer, Jose D. Debes

“…We analyzed demographic and comorbid variables and laboratory tests on admission and during hospitalization. LFT over twice the upper limit of normal (ALEx2) were also evaluated in relation to a variety of factors on admission and during hospitalization. …”
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ALMA/SCUBA-2 COSMOS Survey: Properties of X-Ray- and SED-selected Active Galactic Nuclei in Bright Submillimeter Galaxies by Ryosuke Uematsu, Yoshihiro Ueda, David M. Alexander, A. M. Swinbank, Ian Smail, Carolina Andonie, Chian-Chou Chen, Ugne Dudzevičiūtė, Soh Ikarashi, Kotaro Kohno, Yuichi Matsuda, Annagrazia Puglisi, Hideki Umehata, Wei-Hao Wang

“…We also identify $4{7}_{-15}^{+16}$ % of the AGN hosts as major merger candidates, which is about twice as high as that in the SMGs without AGNs. This suggests that major mergers play a key role in triggering AGN activity in bright SMGs.…”
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Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project by Sakolwat Montrivade, Pairoj Chattranukulchai, Sarawut Siwamogsatham, Yongkasem Vorasettakarnkij, Witthawat Naeowong, Patchaya Boonchayaanant, Anut Sakulsupsiri, Aekarach Ariyachaipanich, Vorarit Lertsuwunseri, Voravut Rungpradubvong, Sudarat Satitthummanid, Sarinya Puwanant, Somchai Prechawat, Suphot Srimahachota, Jarkarpun Chaipromprasit, Wacin Buddhari, Smonporn Boonyaratavej, Surapun Sitthisook, Peera Buranakitjaroen, Apichard Sukonthasarn, Somkiat Sangwatanaroj

“…All patients were instructed to manually measure their HBP twice a day for the duration of at least one week using the same validated automated, oscillometric telemonitoring devices (Uright model TD-3128, TaiDoc Corporation, Taiwan). …”
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Mobile Toolbox sequences task: development and validation of a remote, smartphone-based working memory test by Jerry Slotkin, Aaron J. Kaat, Stephanie Ruth Young, Elizabeth M. Dworak, Miriam A. Novack, Yusuke Shono, Hubert Adam, Cindy J. Nowinski, Sarah Pila, Zahra Hosseinian, Maria Varela Diaz, Anyelo Almonte-Correa, Keith Alperin, Monica R. Camacho, Monica R. Camacho, Bernard Landavazo, Bernard Landavazo, Rachel L. Nosheny, Rachel L. Nosheny, Michael W. Weiner, Michael W. Weiner, Richard C. Gershon

“…In Study 3 (N = 147), participants completed MTB measures twice, remotely on their own devices, with a 2–week interval between sessions.ResultsSequences exhibited moderately high correlations with a comparable NIHTB test and external measures of a similar construct, while exhibiting a lower correlation with an unrelated test, as hypothesized. …”
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Comparative Analysis of the Outcomes of Laparoscopic Right Hemicolectomy with D2 and D3 Lymphadenectomy in the Treatment of Patients with Right Colon Cancer by A. A. Nevolskikh, V. A. Avdeenko, Yu. Yu. Mikhaleva, T. P. Pochuev, P. V. Sokolov, R. F. Zibirov, I. P. Reznik, N. D. Silin, L. O. Petrov, S. A. Ivanov, A. D. Kaprin

“…In the group with D2 lymph node dissection, distant metastases were recorded twice as often as in the group with D3 lymph node dissection — in 8 (11.8 %) and 4 (5.9 %) patients, respectively (p = 0.365). …”
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Chinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trial by Nicola Robinson, Mei Han, Ling Yan, Vincent Chi Ho Chung, Jian-Ping Liu, Hui-Juan Cao, Shi-Bing Liang, Hong-Jie Cheng, Qiao-Yan Zhang, Yu-Fei Li, Ze-Yu Yu, Ling-Yao Kong, Yan-Mei Cai, Li-Bao An, Bao-Tuan Zhao, Shan-Shan Xu, Nai-Wei Zhang, Bo-Yi Jia, Wei-Fang Liu, Fang Niu, Ba-Teer Wu, Jin-Ming Song, Shu-Xin Jia, Meng-Meng Shi, Xiao-Na Zhang

“…In addition, they were required to have an irritable bowel syndrome symptom severity score (IBS-SSS) of at least 75.Interventions TXYF granules (3.7 g) twice daily (taken orally before meals) or placebo for 8 weeks.Primary and secondary outcomes The primary outcome was the response rate measured by the change in IBS-SSS compared with baseline at week 8. …”
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Sources and Transmission Routes of Carbapenem-Resistant <i>Pseudomonas aeruginosa</i>: Study Design and Methodology of the SAMPAN Study by Anneloes van Veen, Selvi N. Shahab, Amber Rijfkogel, Anne F. Voor in ’t holt, Corné H. W. Klaassen, Margreet C. Vos, Yulia Rosa Saharman, Anis Karuniawati, Silvia Zelli, Desy De Lorenzis, Giulia Menchinelli, Giulia De Angelis, Maurizio Sanguinetti, Merel Kemper, Anniek E. E. de Jong, Sima Mohammadi, Valentine Renaud, Irena Kukavica-Ibrulj, Marianne Potvin, Guillaume Q. Nguyen, Jeff Gauthier, Roger C. Levesque, Heike Schmitt, Juliëtte A. Severin

“…Additionally, samples will be taken twice from wet hospital environments and monthly from the hospitals’ (drinking) water system, hospital and municipal wastewater treatment plants, and receiving rivers. …”
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Association of Early and Late Contrast-Associated Acute Kidney Injury and Long-Term Mortality in Patients Undergoing Coronary Angiography by Zhubin Lun, Jin Liu, Liwei Liu, Jingjing Liang, Guanzhong Chen, Shiqun Chen, Bo Wang, Qiang Li, Haozhang Huang, Zhidong Huang, Danyuan Xu, Yunzhao Hu, Ning Tan, Jiyan Chen, Yong Liu, Jianfeng Ye

“…We retrospectively enrolled 3206 patients with preoperative serum creatinine (Scr) and at least twice SCr measurement after CAG. CA-AKI was defined as an increase ≥50% or ≥0.3 mg/dL from baseline in the 72 hours after the procedure. …”
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Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation by S.Z. Raduan, Q.U. Ahmed, M.R.A. Rusmili, A.S.M. Sabere, M.S. Haris, M.F. Shaikh, W.A.W. Sulaiman, M.H. Mahmood

“…In the full experimental design, both neurotoxins were administered intraperitoneally at 3 distinct doses (low, medium, and high) twice weekly for 21 days. At 3 time-points, behavioural tasks were conducted on day 7 (short duration), day 14 (moderate duration), and day 21 (long duration). …”
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Exploring the effect of cold stress on the semen quality parameters of buffalo bulls by Karpenahalli Ranganatha Sriranga, Pawan Singh, Ravinder Singh, Tejeshwari Satpute, Prince Vivek, Tushar Kumar Mohanty, Pradeep Kumar, Ranjit Singh Kataria, Megha Pande, Manishi Mukesh

“…Semen collection of these bulls was done twice during the peak of winter and spring seasons with overall average ambient temperature (°C) of 12.55±0.22 and 20.21±0.68, respectively, and blood was collected on the same day for biochemical analysis. …”
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Trifluridine-tipiracil in previously treated patients with oestrogen receptor-positive, HER2-negative metastatic breast cancer (BOOG 2019-01 TIBET trial): a single-arm, multicentre... by Niels A.D. Guchelaar, Ron H.J. Mathijssen, Maaike de Boer, Marlies L. van Bekkum, Joan B. Heijns, Birgit E.P.J. Vriens, Mandy M. van Rosmalen, Lonneke W. Kessels, Lisanne Hamming, Karin J. Beelen, Peter Nieboer, Susan M. van den Berg, Esther Oomen-de Hoop, Rhodé M. Bijlsma, Monique E.M.M. Bos

“…The participants received trifluridine-tipiracil 35 mg/m2 orally twice a day on days 1–5 and days 8–12 during a 28-day cycle until disease progression, unacceptable toxicity, or withdrawal of consent. …”
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