Analysis of Dental Enamel Surface Submitted to Fruit Juice Plus Soymilk by Micro X-Ray Fluorescence: In Vitro Study by Janaína Salmos Brito, Alexandrino Santos Neto, Luciano Silva, Rebeca Menezes, Natália Araújo, Vanda Carneiro, Lara Magalhães Moreno, Jéssica Miranda, Pâmella Álvares, Giselle Nevares, Felipe Xavier, José Alcides Arruda, Ricardo Bessa-Nogueira, Natanael Santos, Gabriela Queiroz, Ana Paula Sobral, Márcia Silveira, Diana Albuquerque, Marleny Gerbi

“…The crowns were submitted to the fruit juice plus soy during 15 days, twice a day. The pH values, acid titration, and Knoop microhardness were recorded and the specimens were evaluated using X-ray microfluorescence (µXRF). …”
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Dairy cows' responses to 2 separation methods after 3 months of cow-calf contact by Anina Vogt, Susanne Waiblinger, Rupert Palme, Uta König von Borstel, Kerstin Barth

“…Fecal and blood samples were collected twice per week from day −1 until +23 relative to separation start for analysis of fecal cortisol metabolites and the immune response. …”
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Mapping Key Populations to Develop Improved HIV and AIDS Interventions: Multiphase Cross-Sectional Observational Mapping Study Using a District and City Approach by Pande Putu Januraga, Endang Lukitosari, Lanny Luhukay, Rizky Hasby, Aang Sutrisna

“…Comparisons with ongoing outreach programs revealed substantial differences: the mapped MSM population was >50% lower than program coverage; the estimates for people who inject drugs were twice as high as the program coverage. …”
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Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression by Daniël G. Aynekulu Mersha, Sarah E. Fromme, Frank van Boven, Gara Arteaga-Henríquez, Annemarie Wijkhuijs, Marianne van der Ent, Raf Berghmans, Bernard T. Baune, Hemmo A. Drexhage, Virgil Dalm

“…Five depressed CVID patients (Hamilton Depression Rating Scale, HDRS >12) could be treated with Tα1 (8 weeks, 1.6 mg daily subcutaneously, 1st week, thereafter 1.6 mg twice weekly). At the start, at 8 weeks and 8 weeks after the last injection, the HDRS was recorded and blood samples drawn for measuring naïve and memory T cells, Th17 and Treg cells, hsCRP, IL-6 and IL-7. …”
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Effect of Du moxibustion in the treatment of Wind-phlegm disturbance vertigo (督灸疗法治疗眩晕风痰上扰证效果观察) by LUO Lihua (罗丽华), LI Silu (李思璐), LONG Yuqin (龙玉琴), YANG Yanni (杨燕妮), GENG Qingwen (耿庆文)

“…All patients received routine nursing during the treatment, and patients in the control group were given Du moxibustion therapy, 30 min per time, twice a week for 2 weeks. The degree of vertigo (posterior circulation ischemia) was measured before and after treatment. …”
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Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef by Marko Terzin, Steven J. Robbins, Sara C. Bell, Kim-Anh Lê Cao, Renee K. Gruber, Pedro R. Frade, Nicole S. Webster, Yun Kit Yeoh, David G. Bourne, Patrick W. Laffy

“…Results Integrating gene-centric metagenomics analyses with 17 physico-chemical variables (temperature, salinity, and particulate and dissolved nutrients) across 48 reefs revealed that associations between microbial functions and environmental parameters were twice as stable compared to taxonomy-environment associations. …”
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A cross-sectional study exploring the predictors of herpes zoster vaccination for people aged over 50 years old in Chaoyang district, Beijing by Jiao Zhang, Shuo Zhang, Bin Jia, Yunhua Bai, Zhen Li, Fang Liu, Yingxue Hu, Xiaojing Guo, Jianxin Ma, Shuming Li, Qian Shi

“…Multivariate logistic regression analysis revealed that certain factors were associated with lower vaccination coverage, including being female, having a low frequency of influenza episodes (less than twice per year), and having chronic diseases. On the other hand, higher vaccination coverage was observed among individuals whose spouses had a master’s degree or higher, those awarded that a history of chickenpox may lead to potential herpes zoster infection, those who were knowledgeable about the herpes zoster vaccine, and those received recommendations from medical staff. …”
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Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response... by Hao Tian, Qin Luo, Liuyang Huang, Liuyang Huang, Liuyang Huang, Guang Chen, Mingsheng Sun, Fanrong Liang

“…The nonlinear dose-response analysis suggests that pain improvement achieves the MCID at 16 treatment sessions, over 8 weeks, with a frequency of twice per week. Furthermore, analysis of the treatment duration chart shows that acupuncture maintains therapeutic effects during the follow-up period. …”
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Effectivity of karamunting Melastoma malabathricum leaves in inhibiting ovarian development of Nile tilapia Oreochromis niloticus by Yogo Tri saloko, Muhammad Agus Suprayudi, Muhammad Zairin Jr.

“…Tilapia fish weighed 13–14 g were kept in an aquarium measuring 100×60×50 cm with a stocking density of 20 fish/ aquarium. Fish were fed twice a day at 8 a.m and 5 p.m in at satiation. Sampling was carried out at the beginning of the study, on day 30th and day 60th. …”
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Effects of Stocking Density on Fatty Acid and Amino Acid Composition in Muscle, Serum Cortisol, Stress and Immune Response in Large Yellow Croaker (<i>Larimichthys crocea</i>) by Youbin Yu, Liang Wang, Wenyun Huang, Duo Yu, Qiaoxuan Sun, Mingcao Cui

“…Large yellow croaker were fed to satiation twice daily (6:00, 17:00). At the end of this trial, the final densities were 10.38 ± 0.50, 14.41 ± 1.06, and 18.71 ± 0.99 kg/m³ in the LD, MD, and HD groups, respectively. …”
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Dust Scattering Albedo at Millimeter Wavelengths in the TW Hya Disk by Tomohiro C. Yoshida, Hideko Nomura, Takashi Tsukagoshi, Kiyoaki Doi, Kenji Furuya, Akimasa Kataoka

“…We also note that the absolute flux uncertainty of ~10% (1 σ ) is measured and used in the analysis, which is approximately twice the usually assumed value.…”
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A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome by Kathleen Campbell, Jeffrey L. Neul, David N. Lieberman, Elizabeth Berry-Kravis, Tim A. Benke, Cary Fu, Alan Percy, Bernhard Suter, David Morris, Randall L. Carpenter, Eric D. Marsh, Jana von Hehn

“…Methods Participants were randomized to either five days treatment with oral ketamine or matched placebo, followed by a nine-day wash-out period and then crossed-over to the opposite treatment. Ketamine was dosed twice daily at 0.75 mg/kg/dose (Cohort 1) or 1.5 mg/kg/dose (Cohort 2). …”
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A dehazing and enhancement algorithm for heterogeneous images of underground mining environments in coal mines by Xuhui ZHANG, Yanbin XIE, Wenjuan YANG, Chao ZHANG, Jicheng WAN, Zheng DONG, Yanqun WANG, Jie JIANG, Long LI

“…The results indicate that compared to the above novel and excellent algorithms in terms of their optimal indicators, the proposed algorithm exhibited that: (1) The average gradients were approximately twice those obtained by CEEF, suggesting elevated image clarity. (2) The average information entropy decreased by approximately 1% compared to that of MRP, implying more information preserved. (3) The standard deviation increased by approximately 6% on average compared to OSFD, representing improved image contrast. (4) The average fog aware density evaluator (FADE) value by approximately 23% compared to CEEF, implying an effective reduction in the haze Therefore, the proposed algorithm can effectively improve the visual effects and quality of blurred images of underground mining environments in coal mines, exhibiting high utility in engineering.…”
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Bayesian reinforcement learning models reveal how great-tailed grackles improve their behavioral flexibility in serial reversal learning experiments by Lukas, Dieter, McCune, Kelsey, Blaisdell, Aaron, Johnson-Ulrich, Zoe, MacPherson, Maggie, Seitz, Benjamin, Sevchik, August, Logan, Corina

“…Their estimated association-updating rate was more than twice as high at the end of the serial reversal learning experiment than at the beginning, and their estimated sensitivities to their learned associations declined by about a third. …”
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Testing a multi-behavioral intervention to improve oral health behaviors in the pediatric dental surgery population: protocol for the PROTECT trial by Joanna Buscemi, Teresa G. Borowski, David Avenetti, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Molly Martin, Molly Martin, Marc S. Atkins, Teresa Marshall, Michael Berbaum, Helen H. Lee, Helen H. Lee

“…Our two primary outcomes are parental assisted toothbrushing (twice/day, 2 min each time) and reduced added sugar consumption (less than 10% of overall daily caloric intake). …”
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Real-World Efficacy and Safety of Avelumab Plus Axitinib in Metastatic Renal Cell Carcinoma: Results from the Ambispective RAVE-Renal Study by Ilya Tsimafeyeu, Vyacheslav Chubenko, Olga Baklanova, Alexey Kalpinskiy, Sufia Safina, Andrei Lebedinets, Vladislav Petkau, Elvira Parsadanova, Maria Turganova, Aleksei Shkurat, Natalia Tovbik, Elena Tkacheva, Yulia Anzhiganova, Olga Novikova, Varvara Bragina, Ruslan Zukov, Rashida Orlova

“…Patients received avelumab (800 mg intravenously every 2 weeks) plus axitinib (5 mg orally twice daily). The primary endpoints were median progression-free survival (PFS) and objective response rate (ORR). …”
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Tofacitinib Efficacy/Safety in Patients with Ankylosing Spondylitis by Baseline Body Mass Index: A Post Hoc Analysis of Phase 2/3 Trials by Hillary Norton, Paula Sliwinska-Stanczyk, Tomas Hala, Bassel El-Zorkany, Lori Stockert, Rajiv Mundayat, Lisy Wang, Christopher T. Ritchlin

“…Methods Data were pooled from phase 2/3 trials; analyses included patients with active AS randomized (1:1) to tofacitinib 5 mg twice daily or placebo, who were stratified by baseline BMI into < 25, ≥ 25 to < 30, and ≥ 30 kg/m2 categories. …”
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Healthcare practitioners as accomplices: a qualitative study of gender affirmation in a context of ambiguous regulation in Indonesia by Benjamin Hegarty, Alegra Wolter, Amalia Puri Handayani, Kevin Marian, Jamee Newland, Dede Oetomo, Ignatius Praptoraharjo, Angela Kelly-Hanku

“…Methods In this qualitative study, we drew on a participatory methodology to conduct 46 semi-structured interviews between October and December 2023, with trans people (10 trans feminine people and 10 trans masculine people, each interviewed twice) and key informants (three healthcare providers and three lawyers and paralegals). …”
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In vivo pharmacokinetic and pharmacodynamic study and cutoff of florfenicol against Riemerella anatipestifer in ducks by Hui-Lin Zhang, Fa-Lei Li, Hui-Yang Chen, Ding-Mei Qin, Shu-Jun Sun, Meng-Meng Zhang, Huan-Zhong Ding, Yong Liu

“…For PD analysis, the infected ducks were administered FF via the i.m. route at doses of 5–80 mg/kg body weight, using 2 dosing regimens involving the administration of FF either once or twice over 24 h. The bacteria were counted 24 h after drug administration. …”
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A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…The forage was just ryegrass at the re-blossoming stage, cut twice a day to avoid any fermentation, and immediately put in the mixing wagon, with no storage, and administered to animals. …”
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