A deep learning-based integrated analytical system for tumor exosome on-chip isolation and automated image identification by Yunxing Lu, Haihui Wang, Zhou Zeng, Jianan Hui, Jiangyu Ji, Hongju Mao, Qiang Shi, Xiaoyue Yang

“…They carry a wide range of bioactive molecules and serve as a crucial role in intercellular communication and tumor progression. Here, we develop an integrated microfluidic system for on-chip exosome isolation and quantum dot-based tumor marker analysis. …”
Get full text

Total Metacarpal Reconstruction with Fascia-Wrapped Fibular Graft Following Ewing Tumor Resection in a Growing Patient by Samer Abdel Al, MD, Muhamad A. Al-Qawasmi, MD, Muntaser Abu Shokor, MD, Hamza M. Khalaf, MD, Mohammad A. Alattar, PT

Subjects: Get full text

Ultrabright contrast agents with synergistic Raman enhancements for precise intraoperative imaging and photothermal ablation of orthotopic tumor models by Yiqun Ma, Shuchi Xia, Annan Hu, Qianyi Zhang, Zhengzhong Shao, Bo Tian, Qinrui Lin

“…Consequently, the agent enables clear delineation of malignant tissues in both orthotopic and subcutaneous tumor models. Beyond its imaging capability, the agent also facilitates photothermal ablation, providing a long-term solution for suppressing tumor recurrence. …”
Get full text

Perioperative Management of a Patient with Hereditary Angioedema and Intestinal Obstruction Secondary to an Ileal Tumor: A Case Report by Antony Peter Gatheru, Anne Kasyoka Barasa, Isaac Karogo Mwangi, Stanley Ngare, Dan Kiptoon, Edwin Oloo Walong

“…Imaging revealed a small bowel tumor necessitating surgical intervention. Pre-operative prophylactic C1-INH was administered, followed by open laparotomy under general anesthesia with endotracheal intubation. …”
Get full text

Serum vascular endothelial growth factor levels in bitches with canine transmissible venereal tumors treated with vincristine sulphate by Esra Kocabaş, Özkan Duru, Hasan Ceyhun Macun

“…<b>Aim:</b> The present study aimed to determine the serum concentrations of vascular endothelial growth factor (VEGF), which is an important factor in tumor angiogenesis, in dogs with transmissible venereal tumor (TVT) and to evaluate the levels of this factor in treatment with vincristine sulphate. …”
Get full text

Feasibility of enzalutamide on patients with recurrent non-muscle-invasive bladder cancer with marker tumors: phase I study by Takashi Kawahara, Shuya Kandori, Takahiro Kojima, Bryan J. Mathis, Masanobu Shiga, Hiroyuki Nishiyama

“…Immunohistochemical analysis did not showed the strong staining of AR in the latest tumors. This is the first clinical study on enzalutamide treatment for NMIBC patients. …”
Get full text

The effects of tumor-derived exosomes enriched with miRNA-211a on B16F10 cells by Mohammad Reza Atashzar, Mohammad Reza Ataollahi, Ali Ghanbari Asad, Parisa Doroudgar, Davar Amani

Get full text

Induction of SUSD2 by STAT3 Activation Is Associated with Tumor Recurrence in HER2-Positive Breast Cancer by Yisun Jeong, Hyungjoo Kim, Daeun You, Soo Youn Cho, Sun Young Yoon, Seok Won Kim, Seok Jin Nam, Jeong Eon Lee, Sangmin Kim

“…Sushi domain-containing protein 2 (SUSD2), a transmembrane protein containing a sushi motif, has been reported to have tumor-promoting functions in various types of cancer, including breast cancer. …”
Get full text

Pharmacokinetic and Biodistribution Assessment of a Near Infrared-Labeled PSMA-Specific Small Molecule in Tumor-Bearing Mice by Joy L. Kovar, Lael L. Cheung, Melanie A. Simpson, D. Michael Olive

“…In vivo targeting and clearance properties were determined in tumor-bearing mice. Organs and tumors were excised and imaged to assess probe localization. …”
Get full text

MRI and FDG PET/CT Findings for Borderline Brenner Tumor of the Ovary: A Case Report and Literature Review by Hiroki Matsutani, Go Nakai, Takashi Yamada, Kazuhiro Yamamoto, Masahide Ohmichi, Keigo Osuga

“…The imaging features of borderline Brenner tumor (BT) of the ovary are very limited, especially regarding apparent diffusion coefficient (ADC) value and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)/CT. …”
Get full text

Calculation of Involved and Noninvolved Organs Doses in Carbon Therapy of Brain Tumor Using GEANT4 Simulation Toolkit by Maria Ahmadi, Seyed Mohammad Motevalli, Payvand Taherparvar, Vahid zanganeh

“…Weight factors were employed to generate a Spread Out Bragg Peak (SOBP).Material and Methods: The study used the ORNL-MIRD phantom to simulate carbon therapy for brain tumors, finding that the optimal energy range for carbon ions was 2420-2560 MeV to effectively cover the tumor. …”
Get full text

Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…Abstract Background Bone-invasive Pituitary Neuroendocrine Tumors (BI PitNETs) epitomize an aggressive subtype of pituitary tumors characterized by bone invasion, culminating in extensive skull base bone destruction and fragmentation. …”
Get full text

Corrigendum #2 to “Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon” by Qingxin Liu, Jialong Fan, Chuang Zhou, Liqun Wang, Bin Zhao, Haibin Zhang, Bin Liu, Chunyi Tong

Get full text

Ocular Inflammatory Myofibroblastic Tumor in the Left Eye with Phthisis Right Eye: A Rare Occurrence in a Child by Sangeeta Shah, Badri Prasad Badhu, Poonam Lavaju, Anju Pradhan

“…Inflammatory myofibroblastic tumor (IMT) is a benign pseudoneoplastic inflammatory condition with the potential for persistent local growth and recurrence that rarely affects the orbit. …”
Get full text

A Gastrointestinal Stromal Tumor of the Stomach Demonstrating a Stepwise Progression from Low- to High-Grade Malignancy by Takahiko Nakajima, Tomonori Ushijima, Atsushi Kihara, Kenichiro Murata, Toshiro Sugiyama, Koichi Tsuneyama, Johji Imura, Junichi Fukushima, Hajime Horiuchi

“…We report a case of a gastrointestinal stromal tumor (GIST) of the stomach that demonstrated a stepwise progression from low- to high-grade malignancy. …”
Get full text

Tumor immune dysfunction and exclusion evaluation and chemoimmunotherapy response prediction in lung adenocarcinoma using pathomic-based approach by Wei Nie, Liang Zheng, Yinchen Shen, Yao Zhang, Haohua Teng, Runbo Zhong, Lei Cheng, Guangyu Tao, Baohui Han, Tianqing Chu, Hua Zhong, Xueyan Zhang, Xiangxiang Pan

Get full text

PER3 suppresses tumor metastasis of oral squamous cell carcinoma by promoting HIF-1α degradation by Yaoxu Li, Bing Li, Kai Yang, Lihua Zhu, Hong Tang, Yinpei Huang, Jinhai Deng, Jun Duan

“…The low expression of period circadian regulator 3 (PER3) in head and neck squamous cell carcinoma is closely correlated with tumor size and invasion depth. Hypoxia-inducible factor 1 subunit alpha (HIF-1α) regulates epithelial-mesenchymal transition (EMT) transcription factors, activates EMT, and promotes tumor metastasis. …”
Get full text

Late Recurrence in Ovarian Dysgerminoma Presenting as a Primary Retroperitoneal Tumor: A Case Report and Review of the Literature by Yuichiro Sato, Tohru Hayashi, Hidetaka Yamamoto, Ichiro Niina, Naoya Kuroki, Takeshi Iwamura, Junji Onishi

“…Ovarian dysgerminoma is a rare type of germ cell tumor. The majority of patient relapses occur within 2 years of diagnosis. …”
Get full text

Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages by Jin-Ming Zhu, Xiu-Lian Quan, Shi-Chao Han, Xue-Jun Fan, He-Ming Li, Shan-Shan Liang, Xi Chen, Ruo-Yu Wang, Xue-Ning Ji

“…For further elucidation of the mechanism, a culture system mimicking the microenvironment of the tumor in humans was needed. We established a model of microencapsulated SGC7901 human GC cells and evaluated the effects of coculturing spheres with tumor-associated macrophages (TAMs). …”
Get full text

Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor by Seong-Hoon Yun, Sang-Heum Han, Joo-In Park

Get full text