Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation by Yong Yi, Guoqiang Wang, Wenhua Zhang, Shuhan Yu, Junjie Fei, Tingting An, Jianqiao Yi, Fengtian Li, Ting Huang, Jian Yang, Mengmeng Niu, Yang Wang, Chuan Xu, Zhi-Xiong Jim Xiao

“…Abstract Glucose deprivation, a hallmark of the tumor microenvironment, compels tumor cells to seek alternative energy sources for survival and growth. …”
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Giant-Cell Tumor of the Distal Ulna Treated by Wide Resection and Ulnar Support Reconstruction: A Case Report by Akio Minami, Norimasa Iwasaki, Kinya Nishida, Makoto Motomiya, Katsuhisa Yamada, Daisuke Momma

“…Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. …”
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Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration by Qingfang Yue, Yuan Zhang, Fei Wang, Fei Cao, Jun Bai, Xianglong Duan

“…However, the potential contribution of m6A modification patterns to the tumor microenvironment (TME) and the therapeutic efficacy of immunotherapy for colorectal cancer (CRC) remain elusive. …”
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Identification of a Novel Prognostic Lymphangiogenesis-Related Signature Associated with Tumor Immunity for Guiding Therapy in Lung Adenocarcinoma by Juan Peng, Dan Liu, Hong-feng Zhang, Qi-hao Hu, Wen Chen, Juan Zou, Juan Zhang, Hui Li, An-bo Gao, Yu-kun Li

“…Anti-lymphangiogenesis treatment is a promising novel therapeutic direction, especially for tumors resistant to conventional therapies. We confirmed the ectopic expression of lymphangiogenesis-related genes (LRGs) in lung adenocarcinoma (LUAD) cohorts based on the TCGA database. …”
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Epidural Fat and Perineural Adipose Tissue Septic Emboli Mimicking Peripheral Nerve Sheath Tumor in a Dog by Yael Merbl, Kelly M. Ramsay, Ashley Hanna, Annie V. Chen, Laura Anne White, Claire R. Burbick

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Hidden in Plain Sight: Incidental Diagnosis of Metastatic Papillary Thyroid Microcarcinoma Without Radiologically Apparent Thyroid Tumor by Natalie Rivera Vargas, MD, Moises Matos, MD, Mustafa Kinaan, MD, FACE

“…Neck ultrasound performed in an imaging center and in our clinic did not reveal thyroid nodules or abnormal appearing lymph nodes. Solid tumor profiling assay identified a neurotrophic tropomyosin receptor kinase (NTRK)-3 fusion: ETV6(4)-NTRK3(14) mutation. …”
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Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

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Overexpression of PLCG2 and TMEM38A inhibit tumor progression in clear cell renal cell carcinoma by Yiqiao Zhao, Liang Yang, Xiaojie Bai, Lu Du, Huan Lai, Yiyang Liu, Ping Chen, Michael E. DiSanto, Xinhua Zhang

“…In summary, we identified potential tumor suppressor factors and stratified ccRCC patients into high-risk and low-risk groups based on these factors. …”
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Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine by Hiroaki Shibata, Shinichi Hashimoto, Kensaku Shimizu, Ryo Kawasato, Tomohiro Shirasawa, Takayuki Yokota, Hideko Onoda, Takeshi Okamoto, Jun Nishikawa, Naofumi Matsunaga, Isao Sakaida

“…To compare the efficacy of using computed tomography enteroclysis/enterography (CTE), capsule endoscopy (CE), and CTE with CE for diagnosing tumor lesions in the small intestine. Materials and Methods. …”
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Evaluation of reproductive and oncological outcomes after fertility-sparing surgery in cervical cancer patients with tumor > 2 cm by Kiarash Bahrehmand, Dóra Vesztergom, Barna Budai, Dániel Lengyel, Edina Lukács, Zoltán Novák

“…Background/objectives: We aimed to evaluate the reproductive and oncological outcomes of patients who underwent fertility-sparing surgery (FSS) despite being considered suboptimal candidates due to tumor size > 2 cm with or without lymph node metastasis. …”
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MicroRNA-129-3p Suppresses Tumor Progression and Chemoradioresistance in Head and Neck Squamous Cell Carcinoma by Tae Mi Yoon, Sun-Ae Kim, Eun Kyung Jung, Young-Kook Kim, Kyung-Hwa Lee, Sang Chul Lim

“…(1) Background: MicroRNA-129 (miR-129) participates in tumor progression and chemoresistance in various cancer types. …”
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Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Sequencing indicates that MSI cyDNA is enriched in microsatellites, which, upon DC uptake, induce anti-tumor immunity in a manner consistent with clinical MSI CRCs. …”
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Gut Microbiota–Tumor Microenvironment Interactions: Mechanisms and Clinical Implications for Immune Checkpoint Inhibitor Efficacy in Cancer by Said SS, Ibrahim WN

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Tegaserod maleate exerts anti-tumor effects on prostate cancer via repressing sonic hedgehog signaling pathway by Maoping Cai, Shengdong Ge, Yaying Hong, Yao Chen, Yang-Zi Ren, Dacai Zhong, Mingkun Chen, Yuan Liu, Zhe-Sheng Chen, Ninghan Feng, Zhanghui Chen, Shan-Chao Zhao

“…In addition, TM suppressed the tumor growth in the cell-derived xenograft (CDX) mouse model in vivo. …”
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Familial Adenomatous Polyposis and Desmoid Tumor Treated with Multivisceral Transplantation and Kidney Autotransplantation: Case Report and Literature Review by Libor Janousek, Robert Novotny, Michal Kudla, Martin Oliverius, Petr Wohl, Joan Minguet, Jan Martinek, Tomas Hucl, Jiri Fronek

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Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC by Zhen Wu, Zhen Yang, Chun Sun Li, Wei Zhao, Zhi Xin Liang, Yu Dai, Qiang Zhu, Kai Ling Miao, Dong Hua Cui, Liang An Chen

“…However, the correlation between systematic determination of somatic genomic alterations in liquid biopsy and tumor biopsy still remained unclear, and the concordance rate between cell‐free DNA (cfDNA) and matched tumor tissue DNA needs to be increased. …”
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Prognostic implications of immune classification based on PD-L1 expression and tumor-infiltrating lymphocytes in endocervical adenocarcinoma by Li-Jun Wei, Zi-Yun Wu, Li-Yan Wu, Ying-Wen Wu, Hao-Yu Liang, Rong-Zhen Luo, Li-Li Liu

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Causality between insulin use and malignant tumors of the digestive system: a two-sample mendelian randomized study by DengZhuo Chen, YongLi Ma, JingHui Li, Liang Wen, GuoSheng Zhang, ChengZhi Huang, XueQing Yao

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Clinical Impact of Endoscopic Submucosal Dissection for Gastric Neuroendocrine Tumors: A Retrospective Study from Mainland of China by Wei-Feng Chen, Ping-Hong Zhou, Quan-Lin Li, Mei-Dong Xu, Li-Qing Yao

“…As a minimally invasive technique, endoscopic resection may benefit patients diagnosed with early stage gastrointestinal neuroendocrine tumors (NETs). However, no studies have yet been published in which endoscopic submucosal dissection (ESD) has been applied for gastric NETs. …”
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Tumor Microenvironment Responsive Key Nanomicelles for Effective Against Invasion and Metastasis in Ovarian Cancer Using Mice Model by Liu Y, Kong L, Yu Y, Zang J, Zhang L, Guo RB, Li ST, Cheng L, Li XT, Chen YQ

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