The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection by Qingqing Chen, Haohao Wu, Xinwei Guo, Ke Gu, Wenjie Wang, Xiaochen Chen, Shengjun Ji, Hui Yang, Jiahao Zhu

“…The systemic immune-inflammation index (SII) has an important role in predicting survival in some solid tumors. However, little information is available concerning the change of the SII (∆SII) in colorectal cancer (CRC) after curative resection. …”
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Comportamiento de la mortalidad según necropsia en Servicios de Medicina Interna y Geriatría de Cienfuegos by Ana Laura Navarro Baldellot, Laidamy Rodríguez Amador, Roine Alberto Pena Olivera, Héctor Javier Cruz de los Santos, Lisanka Fumero Roldán, Samuel Sánchez Sánchez

“…Los mejores niveles de concordancia clínico-patológica se dieron en las enfermedades del sistema nervioso central, los tumores y las patologías respiratorias. Existió una peor correlación entre las enfermedades digestivas, algunas infecciones y las patologías circulatorias.…”
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Factores de riesgo modificables en pacientes con cáncer de mama by Wilmer Ramírez Carmona, Julio Padrón González, Maikel Valero Carmona, Beatriz Díaz Fabregat

“…<strong>Fundamento:</strong> el cáncer de mama en Cuba constituye la primera localización y segunda causa de muerte por tumores malignos en el sexo femenino. La identificación de factores de riesgo modificables, es todavía un reto dentro del trabajo comunitario. …”
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Investigating the Use of Generative Adversarial Networks-Based Deep Learning for Reducing Motion Artifacts in Cardiac Magnetic Resonance by Ma ZP, Zhu YM, Zhang XD, Zhao YX, Zheng W, Yuan SR, Li GY, Zhang TL

“…Ze-Peng Ma,1,2,&ast; Yue-Ming Zhu,3,&ast; Xiao-Dan Zhang,4 Yong-Xia Zhao,1 Wei Zheng,3 Shuang-Rui Yuan,1 Gao-Yang Li,1 Tian-Le Zhang1 1Department of Radiology, Affiliated Hospital of Hebei University/ Clinical Medical College, Hebei University, Baoding, 071000, People’s Republic of China; 2Hebei Key Laboratory of Precise Imaging of inflammation Tumors, Baoding, Hebei Province, 071000, People’s Republic of China; 3College of Electronic and Information Engineering, Hebei University, Baoding, Hebei Province, 071002, People’s Republic of China; 4Department of Ultrasound, Affiliated Hospital of Hebei University, Baoding, Hebei Province, 071000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiao-Dan Zhang, Department of Ultrasound, Affiliated Hospital of Hebei University, No. 212 of Yuhua East Road, Lianchi District, Baoding, 071000, People’s Republic of China, Tel +86 17325535302, Email xiaodanzhangzxd@126.comObjective: To evaluate the effectiveness of deep learning technology based on generative adversarial networks (GANs) in reducing motion artifacts in cardiac magnetic resonance (CMR) cine sequences.Methods: The training and testing datasets consisted of 2000 and 200 pairs of clear and blurry images, respectively, acquired through simulated motion artifacts in CMR cine sequences. …”
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A multidimensional assessment of adverse events associated with paliperidone palmitate: a real-world pharmacovigilance study using the FAERS and JADER databases by Siyu Lou, Zhiwei Cui, Yingyong Ou, Junyou Chen, Linmei Zhou, Ruizhen Zhao, Chengyu Zhu, Li Wang, Zhu Wu, Fan Zou

“…Noteworthy, unexpected signals not listed in the drug label were also identified, such as psychosexual disorders, prolactin-producing pituitary tumors, suicide attempt, and sudden death. The median onset time for all ADEs was 40 days. …”
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Enhancing doctor-patient communication using large language models for pathology report interpretation by Xiongwen Yang, Yi Xiao, Di Liu, Yun Zhang, Huiyin Deng, Jian Huang, Huiyou Shi, Dan Liu, Maoli Liang, Xing Jin, Yongpan Sun, Jing Yao, XiaoJiang Zhou, Wankai Guo, Yang He, WeiJuan Tang, Chuan Xu

“…Materials and methods This study analyzed text pathology reports from four hospitals between October and December 2023, focusing on malignant tumors. Using GPT-4, we developed templates for interpretive pathology reports (IPRs) to simplify medical terminology for non-professionals. …”
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Long term outcomes associated with the use of perioperative systemic chemotherapy on low grade appendiceal mucinous neoplasms with pseudomyxoma peritonei treated with cytoreductive... by Samantha M. Ruff, Gyulnara Kasumova, Manoj Palavalli, Oliver S. Eng, Laura Lambert, Callisia Clarke, Sameer Patel, Jula Veerapong, Keith Fournier, Daniel Abbott, Charles Staley, Travis Grotz, Fabian Johnston, Mustafa Raoof, Sean Dineen, Jordan M. Cloyd, Alex C. Kim

“…IntroductionLow grade appendiceal mucinous neoplasms (LAMN) are indolent tumors that lack invasive potential but may present as pseudomyxoma peritonei. …”
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Characterization and Detection Strategy Exploration in Cryptogenic Hepatocellular Carcinoma: Insights From a Super‐Aged Region in Japan by Takaaki Sugihara, Takakazu Nagahara, Takuya Kihara, Suguru Ikeda, Yoshiki Hoshino, Yukako Matsuki, Takuki Sakaguchi, Hiroki Kurumi, Takumi Onoyama, Tomoaki Takata, Tomomitsu Matono, Hajime Isomoto

“…Notably, individuals with c‐HCC, typically aged 60 and above (median age 76.0), exhibited a women predominance and presented with larger tumors (4.5 cm vs. 2.5 cm), correlating with a poorer prognosis. …”
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The potential synergistic effect of combining doxorubicin with vorinostat in urothelial carcinoma therapy by Cheng-Huang Shen, Shou-Chieh Wang, Kah-Min Lee, Hsin-Ting Liu, Szu-Wei Huang, Jin-Yi Wu, Yi-Wen Liu

“…The combination of doxorubicin and vorinostat also significantly inhibits the growth of BFTC 905 tumorspheres and BFTC 905 xenograft tumors in mice. In conclusion, our findings demonstrate that the combination of doxorubicin with vorinostat could potentially serve as a new treatment regimen for urothelial bladder cancer, for avoiding the high-dose side effect of doxorubicin.…”
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Secreted LGALS3BP facilitates distant metastasis of breast cancer by Seung-Su Kim, Issac Park, Jeesoo Kim, Na-Lee Ka, Ga Young Lim, Mi-Ye Park, Sewon Hwang, Ji-Eun Kim, So Yeon Park, Jong-Seo Kim, Hyun-Woo Rhee, Mi-Ock Lee

“…Secreted proteins from tumors play important roles in cancer metastasis but previous methods for isolating secretory proteins had limitations in identifying novel targets. …”
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The Application of Three-dimensional Shear Wave Elastography in the Detection of Inguinal Lymph Node Metastasis in Gynecological Malignancies by Yuping Shen, Jiulong Dai, Jiami Li, Man Lu

“…Conclusions: 3D-SWE, particularly using the sagittal Emax parameter, effectively distinguishes benign lymph nodes from metastatic ones by quantitatively evaluating the stiffness of ILNs in relation to gynecological tumors. Serving as a dependable diagnostic method for lymph nodes, 3D-SWE may help reduce the necessity for invasive biopsy procedures in some cases.…”
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Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…It also enhances gastrointestinal mobility and reduces the risk of specific tumors such as colorectal cancer and hepatocellular carcinoma. …”
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Automatic MRI Lymph Node Annotation From CT Labels by Souraja Kundu, Yuji Iwahori, M. K. Bhuyan, Manish Bhatt, Boonserm Kijsirikul, Aili Wang, Akira Ouchi, Yasuhiro Shimizu

“…Moreover, existing cross-modal annotation methods primarily focus on large tumors and require large datasets, making them unsuitable for small lymph nodes with less training data. …”
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Solitary vitreous cysts: a series of case reports by A.B. Galimova, I.V. Baranchikova, G.I. Garipova, I.R. Karachurina, R.Yu. Ziyazetdinova

“…It is imperative to differentiate vitreous cysts from other conditions that may present with similar symptoms, such as ocular toxoplasmosis, cysticercosis, echinococcosis, and pigmentary tumors. </p> <p> <b>Keywords: </b>cyst, vitreous body, pigmentary retinal degeneration, toxoplasmosis, cysticercosis, echinococcosis. …”
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CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway by Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z

“…Siqi Jiang,1,2 Linlin Ou,1,2 Yueqi Wang,1,2 Kai Su,1,2 Zhipei Chen,1,2 Lihong He,1,2 Xun Xu,1,2 Bin Cheng,1,2 Juan Xia,1,2 Zhaona Fan1,2 1Hospital of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of ChinaCorrespondence: Zhaona Fan; Juan Xia, Hospital of Stomatology, Sun Yat-sen University, No. 56 Lingyuanxi Road, Guangzhou, Guangdong, 510055, People’s Republic of China, Tel +86 20 87394123 ; +86 20 83741891, Fax +86 20 83822807, Email fanzhn3@mail.sysu.edu.cn; xiajuan@mail.sysu.edu.cnPurpose: Circular RNAs (circRNAs) are associated with the progression of tumors and hold promise as potential biomarkers for liquid biopsy. …”
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Analyzing Serum Level Changes in Dehydroepiandrosterone Sulfate, Dihydrotestosterone, Progesterone, and Prolactin after Radioactive Iodine Treatment for Papillary Thyroid Carcinoma by Mehrosadat Alavi, Mohammad Atefi, Farzaneh Raeisi

“…Introduction: Effective treatment of papillary thyroid carcinoma (PTC) is total thyroidectomy which is followed by radioactive iodine therapy (RIT) to ablate pathologic thyroid remnants and treat metastatic tumors. However, there are concerns about possible side effects of RIT on different hormones that are important in different aspects including the immune defense system, cardiovascular system, pregnancy, and reproductive health. …”
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Diagnostic value of dual-layer spectral detector CT parameters for differentiating high- from low-grade bladder cancer by Li Chen, Lili Xu, Xiaoxiao Zhang, Jiahui Zhang, Xin Bai, Qianyu Peng, Erjia Guo, Xiaomei Lu, Shenghui Yu, Zhengyu Jin, Gumuyang Zhang, Yi Xie, Huadan Xue, Hao Sun

“…Multivariable analysis found that AEF was the best predictor of high-grade tumors (p = 0.006). With AEF higher in high-grade BCa, AEF results were as follows: area under the curve (AUC), 0.924 (95% confidence interval, 0.861–0.988); sensitivity, 95.5%; specificity, 81.0%; and accuracy, 85.9%. …”
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Retinoblastoma. Part 2.&nbsp; Treatment strategies for intraocular retinoblastoma by S.V. Ivanova, S.A. Kuleva, N.N. Sadovnikova, M.I. Komissarov, M.N. Chistyakova, A.V. Khokhlova, N.A. Shchegoleva

“…Petersburg, Russian Federation</b> </p> <p> <i>Retinoblastoma is one of the most common retinal tumors in young children. Current early diagnostic and treatment strategies focus on the possibility to implement eye-preserving therapies. …”
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Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights by Juan Li, Xuan Wang, Li Zhou, Jun Guo, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xiangyong Gu, Binlei Liu, Hui Tian, Han Hu

“…Antitumor efficacy was evaluated using the Response Evaluation Criteria in Solid Tumors and immune-RECIST guidelines. NCT04386967 is the clinical trial identifier.Results All 44 patients were enrolled. …”
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High Ki67 expression, HER2 overexpression, and low progesterone receptor levels in high-grade DCIS: significant associations with clinical practice implications by Hossein Schandiz, Hossein Schandiz, Lorant Farkas, Lorant Farkas, Daehoon Park, Yan Liu, Yan Liu, Solveig N. Andersen, Torill Sauer, Jürgen Geisler, Jürgen Geisler

“…This elucidation underscores the translational significance of Ki67 as a prognostic and predictive biomarker in DCIS, with implications for personalized treatment paradigms and patient outcomes.BackgroundThe Ki67 proliferation index is widely used in various tumors, including invasive breast carcinoma (IBC). …”
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