Neoplasia mucinosa del apéndice cecal by Yinett Hernández León, Julio Jesús Jimenez Galainena, Osyari Ipsan Muñoz, Liuba Luisa Arteche Hidalgo, Lina Isabel Rodríguez Hernández

“…En el examen histopatológico se observó que al apéndice cecal pertenecen 10 x 8 x 5 cm con lesión tumoral en la base y parte del cuerpo; al corte se observó salida de material viscoso, mucoide, amarillento, áreas quísticas de menos de 1 cm, vasos congestivos, presencia de glándulas mucosas con células que muestran escasa atipia y una invasión expansiva que afecta la capa muscularis mucosae con pérdida focal y fibrosis ligera de la submucosa. …”
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Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis by Alia Khalil, Sahar Al Toufaily, Wassim Shebaby, Marissa El Hage, Dima Mroue, Wissam Faour, Mohamad Mroueh

“…Abstract Background Cisplatin is an anti-cancer drug used to treat a plethora of solid tumors. However, it is associated with dose dependent nephrotoxicity limiting its use as anticancer agent. …”
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Necesidades de aprendizaje del especialista en Medicina General Integral para el diagnóstico precoz del cáncer de mama by Lidia Torres Ajá, Miriam Iglesias León, Carlos Zerquera Álvarez

“…<strong>Fundamento: </strong>el cáncer mamario es la primera causa de muerte por tumores malignos en el sexo femenino. La evolución y sobrevida de estas pacientes depende, en gran medida, de la realización de un diagnóstico precoz, el cual está condicionado por los conocimientos que tengan los profesionales de la atención primaria acerca de esta enfermedad. …”
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Accuracy-dependent dose-constraints and dose-based safety margins for organs-at-risk in radiotherapy by Joep C. Stroom, Sandra C. Vieira, Carlo Greco, Sebastiaan M.J.J.G. Nijsten

“…Background and purpose: Geometrical uncertainties in radiotherapy are generally accounted for by margins for tumors, but their effect on organs-at-risk (OARs) is often ignored. …”
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Mendelian randomization analysis of the causal relationship between trimethylamine N-oxide and its precursors and Parkinson’s disease by Bei Zhang, Ruijie Zhang, Huiming Ren, Qiongfeng Guan, Weinv Fan, Liyuan Han

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CircWDR78 inhibits the development of colorectal cancer by regulating the miR-653-3p/RGS4 axis by Chu Hao, Yunju Pu, Jiunian Li, Zhi Zhong, Zhaohui Huang, Xue Wang

“…These noncoding RNA molecules, characterized by their unique closed loop structure, displayed close associations with the progression of tumors. Methods Actinomycin D experiment and RNA digestion experiment were used to verify the circular structure characteristics of circWDR78. …”
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PRESENCIA DEL MARCADOR LMP-1 DEL VIRUS EPSTEIN-BARR EN LINFOMAS DE CANINOS by L. C. Veloza, M. Collazos, N. Olaya, S. Salas, A. Corredor, H. Díez, I. Castellanos, M. F. Gutiérrez

“…El virus Epstein-Barr ( ebv ) es un virus de alta prevalencia en humanos que se asocia con tumores de la línea linfoide B. En caninos se dispone de pocos reportes sobre la presencia del ebv y su rol en esta especie. …”
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Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis by Qiong Zhang, Jia Duan, Yuanmei Zhang, Lei Yang, Duo Li

“…Neoadjuvant chemotherapy may shrink tumors and improve surgical outcomes, while adjuvant chemotherapy targets residual disease post-surgery. …”
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circICMT upregulates and suppresses the malignant behavior of bladder cancer by Xin Luo, FangMei Xie, Guoqiang Qin, Ge Zou, Xu Lu, Chaofeng Zhang, Zeping Han, Ying Zhao, Xiaoyu Song, WenFeng Luo, Yongsheng Li, JinHua He, Jian Shen

“…Increasing evidence shows that circRNA plays an important role in regulating gene expression in tumors. circICMT is a circular RNA produced by the ICMT gene. …”
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Multidisciplinary Approach to Perihilar and Intrahepatic Cholangiocarcinoma: A Single-Center Experience by Adnan Gundogdu, Taha Anil Kodalak, Hakan Kucukaslan, Serdar Topaloglu, Ummuhan Turali, Sukru Oguz, Davut Dohman, Hasan Dinc, Feyyaz Ozdemir, Mehmet Arslan, Umit Cobanoglu, Erdem Karabulut, Adnan Calik, Mehmet Halil Ozturk

“…We aimed to investigate the clinical characteristics of both tumors and the outcome of our treatment policy. …”
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Volatile Organic Compounds as Biomarkers of Gastrointestinal Diseases and Nutritional Status by Mariangela Rondanelli, Federica Perdoni, Vittoria Infantino, Milena Anna Faliva, Gabriella Peroni, Giancarlo Iannello, Mara Nichetti, Tariq A. Alalwan, Simone Perna, Clementina Cocuzza

“…Four studies examined VOCs in gastric and colorectal tumors showing a change in metabolic biomarkers of cancer patients compared to the control group. …”
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Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years by Yeshong Park, Ho-Seong Han, Seung Yeon Lim, Hyelim Joo, Jinju Kim, MeeYoung Kang, Boram Lee, Hae Won Lee, Yoo-Seok Yoon, Jai Young Cho

“…<i>Conclusions</i>: TO after liver resection improved with advances in minimally invasive techniques and parenchymal sparing procedures, even in older patients with more comorbidities and advanced tumors.…”
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Charlson syndrome index predicted survival in pancreatic cancer patients received immunotherapy by Nan Zhang, Nan Zhang, Shiyun Chen, Yue Shi, Zhikuan Wang, Ru Jia, Guanghai Dai, Guanghai Dai

“…ObjectiveThe Charlson Comorbidity Index (CCI) is a widely utilized assessment tool for evaluating the mortality rate among patients with chronic diseases and tumors. Currently, there is a dearth of research investigating the correlation between CCI and survival rates in advanced pancreatic cancer patients received immunotherapy. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…Pre-clinical data have shown that hyperthermia combined to local pleural chemotherapy increased the immune response against tumors. Recently, pressurized intraperitoneal aerosol chemotherapies (PIPAC) showed improved cytostatic penetration in abdominal carcinosis with a 10-fold-lower chemotherapy dose and minimal side-effects. …”
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GH inhibits ALV-J replication and restricts cell cycle by activating PI3K/Akt signaling pathway by Junliang Xia, Ling Lin, Rongyang Ju, Chengxun Xu, Guodong Mo, Xiquan Zhang

“…Avian leukosis virus subgroup J (ALV-J) is an exogenous tumorigenic retrovirus that primarily induces immunosuppression, growth retardation, decreased egg production, tumors formation, and even death in chickens. Previous studies have suggested that GH is involved in the regulation of innate immunity and inflammation. …”
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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

“…Pathogenic/likely pathogenic germline variants in the BRCA1 and BRCA2 genes are associated with an increased risk of developing cancer, particularly breast and/or ovarian tumors. The identification and correct classification of these variants is crucial to find individuals with an increased risk of cancer and to support physicians in their clinical and therapeutic decisions. …”
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Pluripotent stem cells from the perspective of developmental potential and their characteristics by In-Won Lee, Sang-Ki Baek, Yeon-Ji Lee, Tae-Suk Kim, Bo-Gyeong Seo, Cheol Hwangbo, Joon-Hee Lee

“…However, if the proliferative capacity of PSCs is not controlled, there is a risk that tumors will form, as this can lead to uncontrolled growth in their proliferative capacity. …”
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Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma Neurospheres by Natália Hogetop Freire, Alice Laschuk Herlinger, Julia Vanini, Matheus Dalmolin, Marcelo A. C. Fernandes, Carolina Nör, Vijay Ramaswamy, Caroline Brunetto de Farias, André Tesainer Brunetto, Algemir Lunardi Brunetto, Lauro José Gregianin, Mariane da Cunha Jaeger, Michael D. Taylor, Rafael Roesler

“…Changes in epigenetic processes such as histone acetylation are proposed as key events influencing cancer cell function and the initiation and progression of pediatric brain tumors. Valproic acid (VPA) is an antiepileptic drug that acts partially by inhibiting histone deacetylases (HDACs) and could be repurposed as an epigenetic anticancer therapy. …”
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Computed tomography–guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable? by Petr Hoffmann, Michal Balik, Martina Hoffmannova, Jindrich Kopecky, Pavel Ryska, Jana Draganovicova, Petr Dvorak

“…Materials and methods: A total of 138 percutaneous biopsies for tumors ranging from 21 to 133 mm in diameter (median, 72 mm) were carried out in 134 patients with suspected mRCC over a 5-year period. …”
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PD-1/PD-L1 inhibitors related adverse events: A bibliometric analysis from 2014 to 2024 by Qingya Song, Zongliang Yu, Wenping Lu, Zhili Zhuo, Lei Chang, Heting Mei, Yongjia Cui, Dongni Zhang

“…Adverse events related to PD-1/PD-L1 inhibitors differ from those associated with CTLA-4 inhibitors and are more commonly observed in the treatment of solid tumors. This study aimed to address the knowledge gap regarding adverse events related to PD-1/PD-L1 inhibitors. …”
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