The Legal System of Gene Therapy Contracts by Dr. Muhannad Othman Khudair

“…This has enabled the treatment of many diseases, such as heart and vascular diseases, cancerous tumors, neurological diseases, viral hepatitis, diabetes, and congenital birth defects, among others. …”
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The utilisation of biliary organoids for biomedical applications by Zhongwen Lei, Yijun Yang, Yang Xiang, Yang Xiang

“…Biliary duct injury, biliary atresia (BA), biliary tract tumors, primary sclerosing cholangitis (PSC), and other diseases are commonly encountered in clinical practice within the digestive system. …”
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Human blood metabolites and gastric cancer: a Mendelian randomization analysis by Chao Zhang, Dao Lai Huang, Kun Zhou, Jin Tao Cai, Dang Liu, Ming Hao Tan, Guan Yu Zhu, Xiang Hua Wu

“…Abstract Background Gastric cancer (GC) remains one of the predominant malignant tumors within the digestive tract, yet its underlying biological mechanisms remain elusive. …”
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Epstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression. by Elliott D SoRelle, Lauren E Haynes, Katherine A Willard, Beth Chang, James Ch'ng, Heather Christofk, Micah A Luftig

“…Conversely, induction of lytic reactivation in latent EBV-positive tumors presents a novel therapeutic opportunity. Therefore, defining the dynamics and heterogeneity of EBV lytic reactivation is a high priority to better understand pathogenesis and therapeutic potential. …”
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Intraoperative Tracheal Obstruction Management among Patients with Anterior Mediastinal Masses by H. Kafrouni, Joelle Saroufim, Myriam Abdel Massih

“…Main search key words were as follows: “tracheal obstruction,” “general anesthesia,” “mediastinum,” and “tumors” Results. The literature supports an increased perioperative risk of airway obstruction with the use of general anesthesia in patients with anterior mediastinal masses. …”
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Evaluation of Mucous Retention Cyst Prevalence on Digital Panoramic Radiographs in the Local Population of Iran by Homa Rastegar, Fereshteh Osmani

“…Inflammatory diseases and cysts such as mucous retention cysts (MRCs) and benign tumors include a large proportion of lesions of the mouth, teeth, and jaw. …”
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Predefined and data-driven CT radiomics predict recurrence-free and overall survival in patients with pulmonary metastases treated with stereotactic body radiotherapy. by Pascal Salazar, Patrick Cheung, Balaji Ganeshan, Anastasia Oikonomou

“…First-order radiomic features were extracted using two methods: 2D CT texture analysis (CTTA) using TexRAD software, and a data-driven technique: functional principal components analysis (FPCA) using segmented tumoral and peri-tumoural 3D regions.<h4>Results</h4>Using both Kaplan-Meier analysis with its log-rank tests and multivariate Cox regression analysis, the best radiomic features of both methods were selected: CTTA-based "entropy" and the FPCA-based first mode of variation of tumoural CT density histogram: "F1." …”
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Somatic Mutaome Profile in Human Cancer Tissues by Nayoung Kim, Yourae Hong, Doyoung Kwon, Sukjoon Yoon

“…Somatic mutation is a major cause of cancer progression and varied responses of tumors against anticancer agents. Thus, we must obtain and characterize genome-wide mutational profiles in individual cancer subtypes. …”
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Diplopia, Convergent Strabismus, and Eye Abduction Palsy in a 12-Year-Old Boy with Autoimmune Thyroiditis by Pedro Marques, Sandra Jacinto, Maria do Carmo Pinto, Catarina Limbert, Lurdes Lopes

“…Pseudotumor cerebri (PTC) is defined by clinical criteria of increased intracranial pressure, elevated intracranial pressure with normal cerebrospinal fluid (CSF) composition, and exclusion of other causes such tumors, vascular abnormalities, or infections. The association of PTC with levothyroxine (LT4) has been reported. …”
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Pathological Characteristics, Prognostic Determinants and the Outcome of Patients Diagnosed with Colorectal Adenocarcinoma at the University Teaching Hospital of Kigali by Delphine Uwamariya, Déogratias Ruhangaza, Belson Rugwizangoga

“…Mean age of the participants was 54.26 years, the main symptom was rectal bleeding (46.5%), rectal adenocarcinoma NOS represented 40.6%, conventional adenocarcinoma was 60.4%, most tumors were of Grade II (54.5%), most common stage was pT3N0 (20.8%), resection margins were free at 71.3%, lympho-vascular invasion was 49.5% of cases, a high immune response was in 71.3% of cases and of 101cases, and 55.4% were still alive at the end of the data collection, with 29.3% of patients have overall survival of 5 years. …”
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46, XY Complete Gonadal Dysgenesis (Swyer Syndrome) Presenting as Primary Amenorrhea in a Normomorphic Adult Female From Kakamega, Kenya by Christian Omoaghe

“…Management includes hormone replacement therapy and gonadectomy because of the increased risk of gonadal tumors. The patient was educated about her condition, initiated on combined contraceptive pills, and counseled on exploratory laparoscopic gonadectomy. …”
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Resolución espontánea de un pseudoquiste pancreático gigante. A propósito de un caso by Jorge Luis Estepa Pérez, Gustavo Becerra Terón, Tahiluma Santana Pedraza

“…Persistía el tinte ictérico y una gran masa tumoral palpable en hemiabdomen superior, de aproximadamente 10 cm., dolorosa y de bordes regulares. …”
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Nano-technological advancements in multimodal diagnosis and treatment by Dinesh Bhatia, Tania Acharjee, Shruti Shukla, Monika Bhatia

“…Unlike traditional treatments, which muddle the distinction between diseased and healthy tissue, gold nanoparticles (AuNPs) directly target tumors, using increased permeability and retention (EPR) effects for crystal-clear, early-stage detection. …”
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Rare Presentation of Cardiotoxicity Related to 5-Fluorouracil by Mariam Charkviani, Natia Murvelashvili, Francisco Barrera, Alisha Sharma, Randa Sharag Eldin, Nur Un Nisa Nabil

“…5-Fluorouracil (5-FU) is a chemotherapeutic agent frequently used for the treatment of solid tumors. In a few cases, 5-FU can be associated with coronary vasospasm, cardiac ischemia, or life-threatening arrhythmias. …”
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Enhancing signal-to-noise ratio in real-time LED-based photoacoustic imaging: A comparative study of CNN-based deep learning architectures by Avijit Paul, Srivalleesha Mallidi

“…Through experimentation with in vitro phantoms, ex vivo mouse organs, and in vivo tumors, we compare basic convolutional autoencoder and U-Net architectures, explore hierarchical depth variations within U-Net, and evaluate advanced variants of U-Net. …”
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A sterilization method for human decellularized vaginal matrices by Jayson Sueters, Leonie de Boer, Freek Groenman, Judith A. F. Huirne, Theo H. Smit, Sebastian A. J. Zaat

“…Abstract Vaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. …”
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Laparoscopic Resection of a Left Upper Quadrant Mass Leading to a Surprise Diagnosis by Hugo J. R. Bonatti, Reinhardt O. Sahmel, Rodrigo B. Erlich

“…The gastric fundus showed multiple nodules, and therefore, a modified sleeve gastrectomy was done; also, a 2 cm nodule in segment 5 of the liver and an omental nodule were removed. The tumors and gastrectomy specimen were placed in an endobag and removed through a periumbilical mini-incision. …”
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The prognostic value of the platelet-to-lymphocyte ratio in multiple myeloma patients treated with a bortezomib-based regimen by Quane Zhang, Yifan Wang, Wenting Shi, Yue Chen, Zhengmei He, Liang Yu, Chunling Wang

“…Previous studies have validated the prognostic significance of the platelet-to-lymphocyte ratio (PLR) in patients with certain solid tumors. However, the relationship between the PLR and prognosis in myeloma patients has not been clearly demonstrated. …”
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Clinical Characteristics of Aldosterone- and Cortisol-Coproducing Adrenal Adenoma in Primary Aldosteronism by Lu Tang, Xintao Li, Baojun Wang, Xin Ma, Hongzhao Li, Yu Gao, Liangyou Gu, Wenyuan Nie, Xu Zhang

“…Analysis of clinical parameters revealed that patients with A/CPAs had larger tumors than those with pure APAs (P<0.05). Moreover, they had higher proportions of cardiovascular complications, glucose intolerance/diabetes, and osteopenia/osteoporosis compared to the pure APA patients (P<0.001). …”
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Organ preservation, for rectal cancer: general overview of the latest data from phase III randomized trials by Syrine Ben Dhia, Damien Chauviere, Diana Mitrea, Renaud Schiappa, Tanguy Pace Loscos, Emmanuel Chamorey, David Baron

“…Introduction: Organ preservation (OP) strategies are gaining interest in improving the quality of life in the management of rectal cancer, particularly for tumors located in the distal or middle rectum. The optimal OP protocol is still not standardized and relies on randomized trials. …”
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