Novel submucosal injection material comprising fully synthetic and self-assembling peptide solution in endoscopic submucosal dissection: A pilot study by Kengo Kasuga, Keigo Sato, Ko Nakata, Hirohito Tanaka, Hiroko Hosaka, Shiko Kuribayashi, Yoji Takeuchi, Toshio Uraoka

“…This study evaluated the safety and feasibility of a new injection solution (PuraLift) in ESD for early-stage gastrointestinal tumors. This prospective, single-arm, single-center pilot study included 11 patients with gastrointestinal neoplasms of the stomach (n = 5) or colorectum (n = 6) who underwent ESD. …”
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Detection of Estrogen Receptor Status in Breast Cancer Cytology Samples by an Optical Nanosensor by Pooja V. Gaikwad, Nazifa Rahman, Pratyusha Ghosh, Dianna L. Ng, Ryan M. Williams

“…We evaluated the nanosensor in vitro prior to testing with 26 breast cancer samples which were collected by scraping the cut surface of fresh, surgically resected tumors. Twenty samples were ER+, and six ER−, representing 13 unique patients. …”
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IFN-γ reprograms cardiac microvascular endothelial cells to mediate doxorubicin transport and influences the sensitivity of mice to doxorubicin-induced cardiotoxicity by Haoyu Ji, Wenya Ma, Xu Liu, Hongyang Chen, Yining Liu, Zhongyu Ren, Daohong Yin, Ao Cai, Zizhen Zhang, Xin Wang, Wei Huang, Leping Shi, Yanan Tian, Yang Yu, Xiuxiu Wang, Yang Li, Yu Liu, Benzhi Cai

“…DOX-induced cardiotoxicity (DIC) severely limits the use for treating malignant tumors and is associated with a poor prognosis. The sensitivity to DIC varies among patients, but the precise mechanisms remain elusive. …”
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Quantum computational infusion in extreme learning machines for early multi-cancer detection by Anas Bilal, Muhammad Shafiq, Waeal J. Obidallah, Yousef A. Alduraywish, Haixia Long

“…Results demonstrate that Q-GBGWO-ELM improves diagnostic accuracy by an average of 6.5% compared to traditional methods, with notable accuracy rates across various cancers: 98.80% for breast cancer, 92.30% for brain tumors, 97.00% for skin cancer, and 96.98% for lung cancer. …”
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Randomized clinical trial of a digital integrative medicine intervention among patients undergoing active cancer treatment by Jun J. Mao, Karolina Bryl, Erin F. Gillespie, Angela Green, Tony K. W. Hung, Raymond Baser, Katherine Panageas, Michael A. Postow, Bobby Daly

“…We conducted a randomized controlled trial to assess the impact of a 12 week digital integrative medicine program, Integrative Medicine at Home (IM@Home), versus enhanced usual care on fatigue severity (primary outcome), comorbid symptoms and acute healthcare utilization (secondary outcomes), in 200 patients with solid tumors experiencing fatigue during treatment. Fatigue severity decreased more in IM@Home than in the control (1.99 vs. 1.51 points; p = 0.04). …”
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Evolution of drug therapy in patients with resectable gastric and esophageal‑gastric junction cancer by M. V. Sedova, M. A. Batov, V. S. Tretyak, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko, A. D. Kaprin

“…Gastric cancer (GC) is the fifth most common malignant neoplasm in the world among all malignant tumors. Currently, the “gold” standard of treatment for patients with non‑metastatic cancer of the stomach and esophageal–gastric junction is surgical treatment, which is complemented by perioperative chemotherapy according to the FLOT scheme, which includes four courses of therapy before surgery and four after. …”
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A prospective, multicenter analysis of the integrated 31-gene expression profile test for sentinel lymph node biopsy (i31-GEP for SLNB) test demonstrates reduced number of unnecess... by J. Michael Guenther, Andrew Ward, Brian J. Martin, Mark Cripe, Rohit Sharma, Stanley P. Leong, Joseph I. Clark, John Hamner, Timothy Beard

“…Methods The i31-GEP SLNB risk prediction accuracy was assessed in patients with T1-T2 tumors enrolled in the prospective, multicenter DECIDE study (n = 322). …”
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Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies by Thaiene Avila Reis, Ana Elise Jaculi, Rubens da Costa Alves, Tais Gratieri, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti, Guilherme Martins Gelfuso, Marcilio Cunha-Filho

“…Considering the feasibility of the aluminum phthalocyanine chloride (AlPcCl) application in the topical photodynamic therapy of cutaneous tumors and the lack of HPLC methods capable of supporting skin permeation experiments using this compound, the aim of this study was to obtain a simple and selective chromatographic method for AlPcCl determination in skin matrices. …”
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AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism by Yang Yang, Dan Li, Zhigang Liu, Kai Zhou, Wenxing Li, Yanqi Yang, Ruifang Sun, Yulong Li

“…Aurora kinase B (AURKB) functions as an important oncogene in various tumors; therefore, in the present study, we aimed to explore the mechanism by which AURKB affects ccRCC development. …”
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Safety and Effectiveness of Endoscopist-Directed Nurse-Administered Sedation during Gastric Endoscopic Submucosal Dissection by Yong Suk Cho, Sang youn Shin, Changhyeok Hwang, Jeonghun Seo, Jong Won Choi, Byung Kyu Park, Sun Young Won, Chun Kyon Lee, Yong Kang Lee, Han Ho Jeon

“…Patients treated with ESD for gastric tumors between 2013 and 2015 were retrospectively collected. …”
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Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma by Taewoo Yang, Yegyun Choi, Jae Won Joh, Steve K. Cho, Dae-Shick Kim, Sung-Gyoo Park

“…Methods. Surgically resected tumors from 199 HCC patients were analyzed for p21, p53, p53 Ser15-P, and proliferating cell nuclear antigen (PCNA) expression using immunohistochemistry. …”
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Quantitative Evaluation of Display Contrast of Gd-EOB-DTPA-Enhanced Magnetic Resonance Images: Effects of the Flip Angle and Grayscale Gamma Value by Yusuke Inoue, Hirofumi Hata, Ai Nakajima, Keiji Matsunaga, Yusuke Ohzeki, Tetsuya Hashimoto, Hiroki Haradome

“…Twenty patients with liver tumors were studied. Hepatobiliary-phase images were acquired at low (12°) and high (30°) FAs. …”
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15-Deoxy-Δ12,14-prostaglandin J2 Induces Apoptosis and Upregulates SOCS3 in Human Thyroid Cancer Cells by Carlos Antônio Trindade-da-Silva, Carolina Fernandes Reis, Lara Vecchi, Marcelo Henrique Napimoga, Marcelo Sperandio, Bruna França Matias Colombo, Patrícia Terra Alves, Laura Sterian Ward, Carlos Ueira-Vieira, Luiz Ricardo Goulart

“…In conclusion, 15d-PGJ2 shows the potential to become a new therapeutic approach for thyroid tumors.…”
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GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma by Zhao-shou Yang, Qin Yang, Xiao-xiao Sun, Kui Xiong, Xiao-ting Zhu, Yi-chen Wang, Qian-yao Ren, Guo-hui Wu, Shi-min Wang, Xu-qin Cao, Xiao-rong Yang, Wen-gong Jiang

“…One of the most prevalent malignant primary brain tumors is primary glioma. Although glutathione peroxidase 8 (GPX8) is intimately associated with carcinogenesis, its function in primary gliomas has not yet been thoroughly understood. …”
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The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis by Min-kyung Yeo, Ja Seong Bae, Sohee Lee, Min-Hee Kim, Dong-Jun Lim, Youn Soo Lee, Chan Kwon Jung

“…The Warthin-like variant of papillary thyroid (WLPTC) is a rare subtype of papillary thyroid carcinoma (PTC) resembling Warthin tumors of the salivary glands. Due to its rarity, the clinicopathologic and molecular features of WLPTC remain unclear. …”
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Deep Learning and Multidisciplinary Imaging in Pediatric Surgical Oncology: A Scoping Review by M. A. D. Buser, J. K. van derRest, M. H. W. A. Wijnen, R. R. deKrijger, A. F. W. van derSteeg, M. M. van denHeuvel‐Eibrink, M. Reismann, S. Veldhoen, L. Pio, M. Markel

“…ABSTRACT Background Medical images play an important role in diagnosis and treatment of pediatric solid tumors. The field of radiology, pathology, and other image‐based diagnostics are getting increasingly important and advanced. …”
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Targeting Shp2 as a therapeutic strategy for neurodegenerative diseases by Jiao Pang, Changqian Cen, Yuan Tian, Xingrui Cao, Liang Hao, Xueshu Tao, Zhipeng Cao

“…As a member of the tyrosine phosphatase family, the role of Shp2 has been studied in tumors, but the research in the nervous system is still in a sporadic state. …”
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Temporal integration of ResNet features with LSTM for enhanced skin lesion classification by Sasmita Padhy, Sachikanta Dash, Naween Kumar, Shailendra Pratap Singh, Gyanendra Kumar, Poonam Moral

“…The approach tackles issues including class imbalance and the necessity for enhanced sensitivity in identifying malignant tumors. The ISIC2020 and HAM10000 benchmark datasets were employed for evaluation, utilizing sophisticated data augmentation methods and weighted loss functions to improve performance. …”
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Germinoma with Involvement of Midline and Off-Midline Intracranial Structures by Monica Graciela Loto, Karina Danilowicz, Santiago González Abbati, Rafael Torino, Alejandro Misiunas

“…Germinomas are malignant intracranial germ tumors, usually found in suprasellar regions. Less than 10% are localized in off-middle structures, and synchronous involvement of both structures has only exceptionally been published. …”
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A novel Pringle maneuver instrument for laparoscopic hepatectomy by Chu Hongpeng, Wang Yongkai, Shen Zhengchao, Xi Shihang, Jiang Bin, Pan Xuan, Wang Xiaoming

“…Methods: Data of patients with liver tumors who underwent laparoscopic hepatectomy between 2017 and 2022 were retrospectively collected. …”
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