Spatial Positioning of RET and H4 Following Radiation Exposure Leads to Tumor Development by Yuri E. Nikiforov

“…A high prevalence of chromosomal rearrangements involving the RET gene was found among these radiation-induced thyroid tumors [2,3]. As a result of such rearrangement, a portion of the RET gene is fused with another gene, typically with the H4 or ELE1. …”
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Retroperitoneal Malignant Peripheral Nerve Sheath Tumor Replacing an Absent Kidney in a Child by Samin Alavi, M. T. Arzanian, Yalda Nilipour

“…He underwent surgical resection of the tumor with a primary impression of Wilms tumor. To the authors’ knowledge, this is the first case of retroperitoneal malignant peripheral nerve sheath tumor and absent kidney. …”
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Impact of Surgical Margin Status and Tumor Volume on Mortality After Robotic Radical Prostatectomy by Zaki Zeidan, Joshua Tran, Yeagyeong Hwang, Linda My Huynh, Mai Xuan Nguyen, Erica Huang, Whitney Zhang, Thomas Ahlering

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Tc-Labeled Cyclic RGD Peptides for Noninvasive Monitoring of Tumor Integrin αβ Expression by Yang Zhou, Young-Seung Kim, Sudipta Chakraborty, Jiyun Shi, Haijuan Gao, Shuang Liu

“…Biodistribution and imaging studies were performed in athymic nude mice bearing U87MG, MDA-MB-435, A549, HT29, or PC-3 tumor xenografts. Immunochemistry was performed using the cultured primary tumor cells and xenografted tumor tissues. …”
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Significance of Biogenetic Markers in Giant Cell Tumor Differentiation and Prognosis: A Narrative Review by Muhammad Taqi, Haseeb ul Rasool, Mobeen Zaka Haider, Munjed Al Muderis

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The effect of temperature constraints on the treatment of tumors using focused ultrasound-induced acoustic streaming by Sebastian E. N. Price, Magnus Aa. Gjennestad, Signe Kjelstrup, Rune Hansen

“…Abstract The transport of drugs into tumor cells near the center of the tumor is known to be severely hindered due to the high interstitial pressure and poor vascularization. …”
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Evaluation of the Potential Prognostic Value of Tumor Budding in Laryngeal Carcinoma by Conventional and Immunohistochemical Staining by Nermine M. Abd Raboh, Ossama M. Mady, Sarah A. Hakim

“…Background. Tumor budding is a promising prognostic indicator in several cancers especially in colorectal cancer. …”
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G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz

“…Finally, our results provide the first demonstration that pharmacological inhibition of GPER activity in vivo prevents estrogen-mediated tumor growth.…”
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Revolutionizing ESCC prognosis: the efficiency of tumor-infiltrating immune cells (TIIC) signature score by Haixia Wang, Shaowei Ma, Zixin Yang, Ren Niu, Haiyong Zhu, Shujun Li, Shaolin Gao, Zhirong Li, Yanhua Tian

Subjects: “…Tumor-infiltrating immune cells (TIIC)…”
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Uncommon Presentation of Stromal Tumor Causing Small Bowel Obstruction: A Case Report by Zamin Adigozalli, Rasim Khalilov, Steffen Seyfried

Subjects: “…gastrointestinal stromal tumor…”
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Gastric Carcinoma with Osteoclast-Like Giant Cells Coexisting with Gastrointestinal Spindle Cell Tumor by Christos Poulios, Triantafyllia Koletsa, Antonis Goulas, Georgia Karayannopoulou, Eleni Vrettou, Ioannis Kostopoulos

“…Sections from the tumor showed gastric adenocarcinoma, stage pT1bpN0. …”
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The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors by Xiaonan Shen, Yao Zhang, Yunjia Zhao, Xiaobo Li, Zhizheng Ge, Hua Xiong, Danfeng Sun, Qinyan Gao, Yun Cui, Xiaoyu Chen, Yingxuan Chen, Jingyuan Fang

“…The coexistence of colorectal polyps with laterally spreading tumors (LSTs) is commonly observed during colonoscopy. …”
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The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity by Mustafa Sibai, Sergi Cervilla, Daniela Grases, Eva Musulen, Rossana Lazcano, Chia-Kuei Mo, Veronica Davalos, Arola Fortian, Adrià Bernat, Margarita Romeo, Collin Tokheim, Jordi Barretina, Alexander J. Lazar, Li Ding, Enrique Grande, Francisco X. Real, Manel Esteller, Matthew H. Bailey, Eduard Porta-Pardo, Enrique Grande, Teresa Alonso-Gordoa, Mario Álvarez-Maestro, Elena Andrada, Ainara Azueta, Raquel Benítez Javier Burgos, Daniel Castellano, M. Angel Climent, Mario Domínguez, Ignacio Durán Albert Font, Isabel Galante, Patricia Galván, Juan F. García, Xavier García del Muro, Félix Guerrero-Ramos, Núria Malats, Miriam Marqués, Pablo Maroto, Jaime Martínez de Villarreal, Ane Moreno-Oya, Jesús M. Paramio, Alvaro Pinto, Aleix Prat, Javier Puente, Oscar Reig, Francisco X. Real

“…Summary: Tumors are complex ecosystems of interacting cell types. …”
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Tracking Tumor Cells in Lymphatics in a Mice Xenograft Model by Magnetic Resonance Imaging by Ting Liu, Haijun Zhou, Rui Xia, Jichun Liao, Changqiang Wu, Hui Wang, Hua Ai, Feng Bi, Fabao Gao

“…To enrich our understanding of the mechanism of tumor lymphatic metastasis, we developed a model system for tracking metastatic tumor cells in the lymphatic system with cellular magnetic resonance imaging (MRI) in live mice to observe the interaction between tumor cells and the lymphatic system. …”
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A Case of Carcinoid Tumors in the Ear Canal With Long-Term Postoperative Follow-Up by Shigeaki Tanahashi, Masami Oonishi, Kenichi Mori, Miki Umeda, Takanori Wakaoka, Hiroki Takahashi

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Primary Spinal Germ Cell Tumors: A Case Analysis and Review of Treatment Paradigms by Joshua J. Loya, Henry Jung, Caroline Temmins, Nam Cho, Harminder Singh

“…Primary intramedullary spinal germ cell tumors are exceedingly rare. As such, there are no established treatment paradigms. …”
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Supra-Acetabular Brown Tumor due to Primary Hyperparathyroidism Associated with Chronic Renal Failure by Rosaria M. Ruggeri, Emanuele Calamoneri, Antonia Russo, Alessandro Sindoni, Baldassarre Mondello, Maurizio Monaco, Michele A. Rosa, Sergio Baldari, Salvatore Benvenga, Alfredo Campennì, Francesco Trimarchi

“…This case is noteworthy because (1) primary hyperparathyroidism was not suspected due to the normocalcemia, likely attributable to the coexistence of chronic renal failure; and (2) it was associated with a brown tumor of unusual location (right supra-acetabular region).…”
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A Patient with Advanced Gastric Cancer Presenting with Extremely Large Uterine Fibroid Tumor by Kwang-Kuk Park, Song-I Yang

“…Introduction. Uterine fibroid tumors (uterine leiomyomas) are the most common benign uterine tumors. …”
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Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy by Amelia C. McCue, Stephen J. Demarest, Karen J. Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman

“…The toxicity of TCEs may be ameliorated through the use of pro-drug forms of the TCE, which are not fully functional until recruited to the tumor microenvironment. This can be accomplished by masking the anti-CD3 arm of the TCE with an autoinhibitory motif that is released by tumor-enriched proteases. …”
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Evaluation of Tumor Heterogeneity of Prostate Carcinoma by Flow- and Image DNA Cytometry and Histopathological Grading by Naining Wang, Claudia Wilkin, Alfred Böcking, Bernhard Tribukait

“…Heterogeneity of prostate carcinoma is one of the reasons for pretreatment underestimation of tumor aggressiveness. We studied tumor heterogeneity and the probability of finding the highest tumor grade and DNA aneuploidy with relation to the number of biopsies. …”
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