Radioresistance in rectal cancer: can nanoparticles turn the tide? by Diogo Coelho, Diogo Estêvão, Maria José Oliveira, Bruno Sarmento

“…Here, we revise the main molecular differences between rectal and colon tumors, exploring the complex orchestration beyond rectal cancer radioresistance and the most promising nanomedicines reported in the literature to improve neoadjuvant therapy response rates. …”
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Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures by Shengjie Cui, Jing Han, Binny Khandakar, Barak Friedman, Domingo Nunez, Gabriel A. Sara, Gabriel S. Levi

“…Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. …”
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Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study by Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.

“…Our results indicate that under glucose deprived conditions, which better reflect the factual glucose-starved solid tumors in vivo, biguanides exert more antiproliferative activities against the three molecular subtypes of breast cancer cell lines examined in this study. …”
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Targeting RNA splicing modulation: new perspectives for anticancer strategy? by Xuemei Lv, Xiaoyu Sun, Yang Gao, Xinyue Song, Xiaoyun Hu, Lang Gong, Li Han, Miao He, Minjie Wei

“…Aberrant RNA splicing is recognized as a molecular characteristic present in almost all types of tumors. Therefore, identifying cancer-specific subtypes from aberrant processing offers new opportunities for therapeutic development. …”
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Anterior Abdominal Wall Pain by A. I. Dolgushina, M. I. Karpova, I. A. Karpov, N. B. Nadtochiy, A. A. Saenko

“…Another group of causes of pain in the anterior abdominal wall is represented by diseases in which areas of infiltration (tumors, endometriosis, infections) or hernial protrusions are determined, in which radiation methods play an important role in diagnosis.Conclusion. …”
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Characterization of adult T-cell leukemia/lymphoma patients with specific skin lesions in a tertiary dermatological service in Brazil by Mariana Valente, José Antonio Sanches, Youko Nukui, Jade Cury-Martins, Bruno Castro Souza, Juliana Pereira, Denis Miyashiro

“…Classification at diagnosis was: 16 (36.4%) chronic (93.7% unfavorable, 6.2% favorable), 14 (31.8%) acute, 10 (22.7%) smoldering, four (9.1%) lymphoma, and none with primary cutaneous tumoral. Regarding skin lesions, 18 (40.9%) had plaques; 15 (34.1%) nodules/tumors; 11 (25.0%) papules; 10 (22.7%) erythroderma; seven (15.9%) patches; two (4.5%) ichthyosis; one (2.3%) purpuric lesions. …”
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Rapidly Progressive Myelopathy Caused by Aggressive Vertebral Hemangioma by Kevin A. Moattari, Rojeh Melikian, Sanjay K. Khurana

“…Vertebral hemangiomas are the most common benign tumors of the spine, having an incidence of 10-12% in the general population. …”
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A select inhibitor of MORC2 encapsulated by chimeric membranecoated DNA nanocage target alleviation TNBC progression by Xiaohan Su, Yunbo Luo, Yali Wang, Peng Qu, Jun Liu, Shiqi Han, Cui Ma, Shishan Deng, Qi Liang, Xiaowei Qi, Panke Cheng, Lingmi Hou

“…Additionally, PMD can markedly enhance the killing effect of Angoline on TNBC tumors. Therefore, PMD-enveloped Angoline provide a highly effective targeted therapeutic regimen for TNBC and may improve the outcome for patients with TNBC.…”
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Scientific-methodical support of gifted teenagers in creative education by Valentina G. Ryndak, Ekaterina S. Mikhaleva

“…The article actualizes the importance of the development of talented teenager potential for productive relationship with society through the acquisition of a teenager personality tumors ("Actual Self", "Potential Self", "Perspective Self"). …”
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Primary Angiosarcoma of the Spleen: An Oncological Enigma by Myoteri Despoina, Dellaportas Dionysios, Ayiomamitis Georgios, Strigklis Konstantinos, Kouroumpas Efstratios, Zizi-Sermpetzoglou Adamantia

“…An 82-year-old woman was admitted with left pleural effusion and a palpable left upper quadrant abdominal mass, secondary to splenomegaly by two large splenic tumors. Classic open splenectomy was performed and angiosarcoma of the spleen was the final histopathological diagnosis, which was primary since no other disease site was revealed. …”
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Voluminous fronto-parietal osteomas: Guided resection with patient-specific cutting guides and reconstruction with a 3D printed hydroxyapatite implant by Lucille de Bengy-Puyvallée, David Poisbleau, Francois Herman, Elisabeth Cobraiville, Jean-Philippe Giot, Loric Galmard

“…Osteomas are benign, well-differentiated bony tumors characterized by gradual progression, commonly observed within the craniofacial skeleton. …”
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Neuroendocrine Cell Carcinoma of Unknown Primary Arising in Long Standing History of Multiple Sclerosis by Stergios Boussios, Vasiliki Kostadima, Anna Batistatou, Ioannis Tourkantonis, George Fotopoulos, Maria I. Argyropoulou, Nicholas Pavlidis

“…Cancer of unknown primary site (CUP) is a well-recognised clinical disorder, accounting for 3–5% of all malignant epithelial tumors. CUP is clinically characterised as an aggressive disease with early dissemination. …”
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Impact of Gd, Pr, Yb, and Nd doping on the magnetic properties of Mg-ferrite nanoparticles by H. Aglan, I. A. Ali, B. M. Ali, S. A. Kandil

“…Compared to existing studies, Ln3+ substituted (Yb, Pr, Gd, and Nd) nanoparticles demonstrate tunable magnetic properties and enhanced SAR performance, offering a more efficient design for hyperthermia treatment of solid tumors. Graphical Abstract…”
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Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma by Tatsuya Morinishi, Yasunori Tokuhara, Hiroyuki Ohsaki, Emi Ibuki, Kyuichi Kadota, Eiichiro Hirakawa

“…Peroxisome proliferator-activated receptor alpha (PPAR-α) belongs to the PPAR family and plays a critical role in inhibiting cell proliferation and tumorigenesis in various tumors. However, the role of PPAR-α in colorectal tumorigenesis is unclear. …”
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Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report by Daniela Oliveira, Vanessa Chaves, José Carlos Martins, Carlos Vaz, Miguel Bernardes, Jorge Almeida

“…Patients with primary SS should be closely monitored for malignancy, not only for hematological cancer, but also for solid tumors. Further research is necessary to understand which are the predictors of cancer proliferation in primary SS patients.…”
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Successful retrieval of lower limbs artery bone cement embolization resulting from percutaneous vertebroplasty: A rare case report by Jiashen Shao, Hai Feng, Bin Liu, Hai Meng, Shili Ning, Yingchi Yang, Yun Yang, Xuehu Xie, Zihan Fan, Zhiwu Zhang, Nan Su, Jinjun Li, Qi Fei

“…It has since expanded to treat osteoporotic vertebral compression fractures, pathologic vertebral fractures resulting from primary or secondary spinal tumors, and traumatic spinal fractures. Despite its benefits, PVP is associated with significant complications, the most common of which is bone cement leakage. …”
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CK20 and CK5/6 Immunohistochemical Staining of Urothelial Neoplasms: A Perspective by Mohammed Akhtar, Sameera Rashid, Mohamed Ben Gashir, Noheir Mostafa Taha, Issam Al Bozom

“…Thus, low-grade urothelial carcinoma manifests CK expression limited to the umbrella cells, while high-grade tumors usually have an expression in the entire thickness of the urothelium except for the basal layer. …”
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Cell Transplantation for Spinal Cord Injury: Tumorigenicity of Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cells by Junhao Deng, Yiling Zhang, Yong Xie, Licheng Zhang, Peifu Tang

“…This review discusses the tumorigenicity of iPSC-derived NS/PCs focusing on the two different routes of tumorigenicity (teratomas and true tumors) and underlying mechanisms behind them, as well as possible solutions to circumvent them.…”
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Chloroquine Treatment Increases Detection of 5-Fluorouracil-Induced Apoptosis In Vivo by Mukesh K. Nyati, Felix Y. Feng, Vinayak D. Kanade, Rabindranath Nayak

“…This technique resulted in a significant increase in the accumulation of apoptotic cells induced by 5-fluorouracil, as detected by propidium iodide staining in solid and ascitic forms of Ehrlich ascitic tumors and in bone marrow cells. We further validated our technique using DNA fragmentation and endonuclease assays. …”
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“Spontaneous epidural hematoma in a pediatric patient following pansinusitis: a case report and review of the literature” by Shahin Nazarpour, Farid Qoorchi Moheb Seraj, Seyed Morteza Sharifzadeh Khavari, Mehran Seadghat, Mohammad Ali Abouei Mehrizi

“…Abstract Background Spontaneous epidural hematoma commonly occurs in patients who have coagulopathy, vascular tumors, and vascular malformations. The association between this entity and maxillofacial infection is rare. …”
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