Serum NLR combined with CA125 and HE4 improves the diagnostic and prognostic efficiency in patients with ovarian cancer by Yun Tian, Yun Tian, Xiabing Li, Xiabing Li, Hongjian Zhang, Hongjian Zhang, Yaping Wang, Yaping Wang, Hongyu Li, Hongyu Li, Qiaohong Qin, Qiaohong Qin

“…This study seeks to identify combination diagnostic and prognostic markers for OC, aiming to improve diagnostic and prognostic efficacy, especially in the early stages.MethodsWe analyzed the targeted biomarkers in a cohort of 104 OC patients and 100 controls, which comprised 50 patients with benign ovarian tumors and 50 healthy women, using enzyme-linked immunosorbent assay (ELISA) and complete blood counting (CBC). …”
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Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study by Pernelle Lavaud, Esma Saada-Bouzid, Renaud Sabatier, Olivia Le Saux, Thibault de la Motte Rouge, Anthony Gonçalves, Elodie Coquan, Jean-Sébastien Frenel, Marta Jiménez, Alice Hervieu, Laurent Mathiot, François Legrand, Claire Cropet, Edith Borcoman, Emmanuelle Charafe

“…The primary efficacy endpoint was the clinical benefit rate (CBR) based on the Response Evaluation Criteria in Solid Tumors V.1.1, which was analyzed using a Bayesian approachResults A total of 31 patients were enrolled and treated in the cervical cancer cohort. …”
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Perfil clínico-epidemiológico de pacientes oncológicos internados em uma Unidade de Terapia Intensiva Pediátrica by Ana Paula Silva e Silva, Larissa da Silva Baltazar, Antônio Felipe Silva Carvalho, Luna Mayra da Silva e Silva, Danielle França Furtado, Nilviane Pires Silva, Talison Taylon Diniz Ferreira, José Antônio Costa Leite

“…Resultados: Os tipos de cânceres infanto-juvenis predominantes foram tumores do sistema nervoso central, (77,5% dos prontuários). …”
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Enhanced preoperative prediction of breast lesion pathology, prognostic biomarkers, and molecular subtypes using multiple models diffusion-weighted MR imaging by Litong He, Feng Li, Yanjin Qin, Yuling Li, Qilan Hu, Zhiqiang Liu, Yunfei Zhang, Tao Ai

“…Notably, IVIM-D and DKI-MK values were significantly different between estrogen receptor (ER)-positive and ER-negative tumors. Progesterone receptor (PR)-positive cancers exhibited lower Mono-ADC, IVIM-D, DKI-MD, SEM-DDC, CTRW-Dm, and CTRW-α values, alongside higher DKI-MK value compared to PR-negative cancers (p < 0.05). …”
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Electroporation assisted delivery of Roussin salt porphyrin-based conjugated carbon nanoparticles for sono–X-ray–photodynamic prostate cancer in vitro and in vivo treatment by Samir Ali Abd El-Kaream, Abed Elrahman Ahmad Mohamad, Sohier Mahmoud El-Kholey, Samia Abd El-Moniem Ebied

“…Rapid advancements in material science have prompted the creation of several SXPs that create cytotoxic species with great selectivity, safety, and noninvasiveness for the treatment of tumors. The current study aims to provide an advanced method of activated cancer treatment by using electroporation to assist the delivery of Roussin salts porphyrin-based conjugated carbon nanoparticles (EP@RRBP-CNP) for the sono–X-ray–photodynamic prostate cancer (PCa) in vivo and in vitro treatment. …”
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Ouabain Modulates Zymosan-Induced Peritonitis in Mice by Jacqueline Alves Leite, Anne Kaliery De Abreu Alves, José Guilherme Marques Galvão, Mariana Pires Teixeira, Luiz Henrique Agra Cavalcante-Silva, Cristoforo Scavone, Alexandre Morrot, Vivian Mary Rumjanek, Sandra Rodrigues-Mascarenhas

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Roles of Oncogenic Long Non-coding RNAs in Cancer Development by Hyunhee Do, Wanyeon Kim

“…It has been shown that abnormal expression of lncRNAs is observed in several human solid tumors. Several studies have shown that many lncRNAs can function as oncogenes in cancer development through the induction of cell cycle progression, cell proliferation and invasion, anti-apoptosis, and metastasis. …”
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Detection of Dysplastic Intestinal Adenomas Using a Fluorescent Folate Imaging Probe by Wei-Tsung Chen, Khashayarsha Khazaie, Guoying Zhang, Ralph Weissleder, Ching-Hsuan Tung

“…Macrophages have long been recognized as a prominent component of tumors. Activated macrophages overexpress folate receptors and we used this phenomenon to image inflammatory reactions in colon dysplasia using a fluorescent folate probe (FFP). …”
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Multiple Cutaneous Metastases as Initial Presentation in Advanced Colon Cancer by Sudheer Nambiar, Asha Karippot

“…We present an extremely rare case of a 68-year-old woman with advanced ascending colon adenocarcinoma that presented with multiple rapidly progressing painless cutaneous metastatic lesions with no other distant metastases. Of all the tumors, breast cancer most commonly spreads as cutaneous metastasis is followed by lung, colorectal, renal, ovarian, and bladder cancers. …”
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Retroperitoneal Lymph Node Dissection as Primary Treatment for Metastatic Seminoma by Brian Hu, Siamak Daneshmand

“…Retroperitoneal lymph node dissection (RPLND) is a standard treatment for nonseminomatous germ cell tumors (NSGCT) that has minimal long-term morbidity. …”
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DNA Methylation: Its Role and Interaction with Epigenetic Modifications in Cancer by Nasreddine El Omari, Saad Bakrim, Mohamed Bakha, Abdelaali Balahbib, Abdelhakim Bouyahya, Chrismawan Ardianto, Long Chiau Ming, Hooi Leng Ser

“…Currently, several investigations have highlighted the involvement of aberrant DNA methylation with certain tumors. Indeed, the methylation of antioncogenes and/or the demethylation of oncogenes are the major alterations that are strongly linked to human cancers. …”
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Nuclear Reprogramming in Mouse Primordial Germ Cells: Epigenetic Contribution by Massimo De Felici

“…This may occur in vivo under still undefined condition, and it is likely at the origin of the formation of germ cell tumors. The phenomenon appears to be reproduced under partly defined in vitro culture conditions, when PGCs are transformed into embryonic germ (EG) cells. …”
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Spices and gastrointestinal health benefits: a state-of-the-art by Pauline Raoul, Campagna Chiara, Gianferrari Elisa, Nicodemo Mirella, Pizzari Ginevra, Marco Cintoni, Emanuele Rinninella, Esmeralda Capristo, Maria Cristina Mele

“…This review presents an overviewof the most common spices highlighting their anti-inflammatory, prebiotic, and anti-tumoral properties. Human clinical trials, specifically randomized controlled trials, are necessary to describe and demonstrate their health benefits to define it as a functional food.…”
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No trilho histórico do cancro: percepções de incurabilidade, invocações sagradas e rejeição da medicina científica by Rui Manuel Pinto Costa

“… Enfermidade frustrante, tanto pela natureza insidiosa do seu crescimento, quanto pela proverbial resistência às tentativas terapêuticas da medicina científica, a compreensão humana sobre o cancro dependeu das crenças médicas sobre a natureza biológica dos tumores malignos, da ineficácia da terapêutica, e ainda dos valores, dor, sofrimento e modo como vemos o nosso próprio corpo. …”
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NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis by Tian Tang, Feng Zeng

“…Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of head and neck cancers. In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. …”
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Experimental assessment of аdversarial attacks to the deep neural networks in medical image recognition by D. M. Voynov, V. A. Kovalev

“…The white-box Projected Gradient Descent attacks were examined based on 8 classification tasks and 13 image datasets containing more than 900 000 chest X-ray and histology images of malignant tumors. An increase of the amplitude and the number of iterations of adversarial perturbations in generating malicious adversarial images leads to a growth of the fraction of successful attacks for the majority of image types examined in this study. …”
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Rehabilitation of Maxillary Defect Using Zygomatic Implant Retained Obturator by Mounika Ayinala, Gautam Shetty

“…Tumors involving the hard palate, maxillary sinus, or nasal cavity require maxillectomy based on the extent of the lesion. …”
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Oral Metastasis of Metaplastic Breast Carcinoma in a Patient with Neurofibromatosis 1 by Ana Paula Molina Vivas, Luana Eschholz Bomfin, Clovis Antonio Lopes Pinto, Ulisses Ribaldo Nicolau, Fabio Abreu Alves

“…Neurofibromatosis type 1 (NF1) has been associated with an increased risk for development of malignancy, especially malignant peripheral nerve sheath tumors. In addition, recently, literature has demonstrated an increased risk of breast cancer in women with NF1. …”
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Characterizing Opine Physiological and Genetic Diversity in Moroccan strains of Allorhizobium vitis, the Causal Agent of Grapevine Crown Gall by Khaoula Habbadi, Hajar Hamzaoui, Imane Hourmatallah, Hiba Yahyaoui, Faiçal Aoujil, Majida Hafidi, Aziz Aziz, Salma El Iraqui El Houssaini

“…Using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF) and specific PCR assays, we identified and characterized opines in tumors induced in tomato plants by Moroccan strains of A. vitis. …”
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Obstructive shock secondary to an unusual cause: primary cardiac lymphoma by Gregoire Ottavy, Laurent Camous, Claire Fieschi, Lucas Della Torre, Jean-David Pommier

“…Abstract Background The medico-surgical management of cardiac tumors when there is a suspicion of malignancy is complex. …”
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