Progressive Dyspnea in a 40-Year-Old Man Caused by Giant Mediastinal Thymolipoma by Mohammad Vaziri, Kamelia Rad

“…Thymolipomas are rare tumors of the anterior mediastinum containing both thymic stroma and an abundance of fat. …”
Get full text

Mature Ovarian Teratoma: Atypical Imaging by S. Wakrim, M. EL Jdid

“…The incidence of a mature ovarian teratoma ranged from 20% to 30% of pediatric ovarian tumors (Sabaa et al., 2009), which is composed of well-differentiated tissues that derive from all three germ cell layers (ectoderm, mesoderm, and endoderm); it is one of the most common benign ovarian neoplasms. …”
Get full text

Intra-Articular Giant Synovial Osteochondroma: Case Reports of the Ankle and Knee Joint by Paolo Fornaciari, Pascal A. Schai, Richard Niehaus, Ulrich G. Exner

“…A 17-year-old man presented with a tumorous mass which had been localized in his left ankle for many years, increasing in volume during the last months. …”
Get full text

A Successful Collagenase and Hyaluronic Acid Topical Use Combined with Antibiotic Therapy in the Treatment of Ulcerative Lesions Arising on Tattoo by Paolo Fioramonti, Pasquale Fino, Martina Ruggieri, Nicolò Scuderi, Maria Giuseppina Onesti

“…The procedure used in making a tattoo consists of puncturing the dermis and depositing an amount of ink, but this decorative technique is not devoid of potential adverse effects, such as infectious complications, hypersensitivity reactions to pigments (lichenoid and granulomatous reactions), the development of benign or malignant tumors, and chronic dermatoses on site of the tattoo. …”
Get full text

Novel MLH1 nonsense variant in a patient with suspected Lynch syndrome by Nobue Takaiso, Issei Imoto, Toshihiko Matsumoto, Akiyo Yoshimura

“…The characteristics of the case met the revised Bethesda guidelines, and the tumors demonstrated a high frequency of microsatellite instability. …”
Get full text

Endoscopic Drainage of an Odontogenic Pterygoid Muscle Abscess by Rickul Varshney, Faisal Zawawi, Marc A. Tewfik

“…The infratemporal fossa (ITF) is a potential space bounded by bony structures that can be occupied by both benign and malignant tumors. It is also a potential area of abscess development, most commonly of dental origin. …”
Get full text

Endoscopic Perspective in Cholangiocarcinoma Diagnostic Process by O. Urban, P. Vanek, V. Zoundjiekpon, P. Falt

“…While cross-sectional imaging studies are usually conclusive for intrahepatic lesions, endoscopy plays an essential role in cases of extrahepatic tumors. Rational utilization of different diagnostic methods based on available evidence is needed. …”
Get full text

A Glucagonoma Presenting as Cerebral Vein Thrombosis and Diabetes by Marina Delli Colli, Bader N. Alamri, Laura Palma, Juan Rivera

“…Glucagonomas are rare pancreatic neuroendocrine tumors (pNETs), malignant in 80% of cases, thus highlighting the importance of early diagnosis and treatment. …”
Get full text

Bone-Immune Cell Crosstalk: Bone Diseases by Giorgio Mori, Patrizia D’Amelio, Roberta Faccio, Giacomina Brunetti

“…In particular, we focused our attention on the major pathogenic mechanism underlying periodontal disease, psoriatic arthritis, postmenopausal osteoporosis, glucocorticoid-induced osteoporosis, metastatic solid tumors, and multiple myeloma.…”
Get full text

Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge by Ronni Andrea Muñoz Tovar, Luis Carlos Alvarez Perdomo, Sandra Milena Rojas Molina, Silvana Jimenez Salazar

“…A widely recognized risk factor is active neoplasia, mainly hematological tumors, in which associated thrombocytopenia can be a frequent complication. …”
Get full text

Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations by Sareena Singh, Shandhini Raidoo, Gaetan Pettigrew, Robert DeBernardo

“…There exists a subgroup of patients with early, high-risk disease, whose management remains controversial, as current data is clouded by inclusion of early stage tumors with different high-risk features for recurrence, unstandardized protocols for surgical staging, and an evolving staging system by which we are grouping these patients. …”
Get full text

Signet Ring Cell Carcinoma of the Vater's Ampulla: A Very Rare Malignancy by K. Daoudi, K. El Haoudi, N. Bouyahia, A. Benlemlih, S. Arifi, N. Mellas, K. Mazaz, A. Amarti, O. El Mesbahi

“…Most tumors affecting Vater's ampulla are adenocarcinomas, and other histological variants are less frequent. …”
Get full text

Quantitative proteomic analysis unveils a critical role of VARS1 in hepatocellular carcinoma aggressiveness through the modulation of MAGI1 expression by Natalia Hermán-Sánchez, Mercedes del Rio-Moreno, Rubén Ciria, Marina E. Sánchez-Frias, Maite G. Fernández-Barrena, Iker Uriarte, Eduardo Chicano-Galvez, Ignacio Ortea, Ángela Peralbo-Molina, Javier Briceño, Matías A. Avila, Manuel Rodríguez-Perálvarez, Raúl M. Luque, Juan L. López-Cánovas, Manuel D. Gahete

Get full text

Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients by Kristen M. Drescher, Poonam Sharma, Henry T. Lynch

“…High levels of microsatellite instability (MSI-high) are a cardinal feature of colorectal tumors from patients with Lynch Syndrome. Other key characteristics of Lynch Syndrome are that these patients experience fewer metastases and have enhanced survival when compared to patients diagnosed with microsatellite stable (MSS) colorectal cancer. …”
Get full text

Incidental Cardiac Lipoma in a Pediatric Patient by Sebahattin Memis, Mehmet Semih Demirtas

“…Cardiac lipomas are primary benign tumors of the heart, consisting mainly of fat cells and the capsule surrounding them. …”
Get full text

Primary Osteosarcoma of the Breast: A Case Report by Anna Rizzi, Alberto Soregaroli, Claudia Zambelli, Fausto Zorzi, Stefano Mutti, Claudio Codignola, Paola Bertocchi, Alberto Zaniboni

“…Adjuvant chemotherapy should be considered for patients with tumors showing aggressive features.…”
Get full text

Radiation Pneumonitis after Radiotherapy of Neck Lymphoma by Min Wei, Jun Cai, Tao Tong, Shihua Yu, Yonghua Yang, Weijia Zhang, Jiyuan Yang

“…Radiotherapy is still one of the effective means for treatment of malignant tumors up to now. Particularly, it is an indispensable effective measure for treatment of some lymphoma patients. …”
Get full text

Case report on paratesticular sarcoma and a focused review of the literature by Shah Abhijit, Kumar Siddhant, Choudhari Arghya, Chawla Arun, Surag K.R.

“…Insidious, usually painless, and rare inguinoscrotal masses arising from paratesticular elements (spermatic cord, epididymis, tunica or the stroma) are known as paratesticular tumors. The overall incidence is less than 5%, and the total number of giant (>10cm) paratesticular liposarcomas is less than 300 cases recorded since 2020. …”
Get full text

PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis by Naoko Okumura, Hitomi Yoshida, Yasuko Kitagishi, Mutsumi Murakami, Yuri Nishimura, Satoru Matsuda

“…PI3K/AKT/PTEN pathway is important in the regulation of angiogenesis mediated by vascular endothelial growth factor in many tumors including leukemia. The signaling pathway is activated in leukemia patients as well as leukemia cell lines together with a decrease in the expression of PTEN gene. …”
Get full text

“Vanishing Penis” and Urinary Retention due to Locally Destructive Penile Cancer by Petros Sountoulides, Athanasios Bantis, Ioannis Zachos, Irene Asouhidou, Athanasios Pantazakos

“…They usually arise from precancerous lesions and present in the form of ulcerative or exophytic tumors. They rarely give rise to urinary symptoms and complications, and are usually easy to diagnose. …”
Get full text