Comparative Analysis of Automated and Handheld Breast Ultrasound Findings for Small (≤1 cm) Breast Cancers Based on BI-RADS Category by Han Song Mun, Eun Young Ko, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Haejung Kim, Myoung Kyoung Kim, Jieun Kim

“…No significant differences were observed in other US findings or tumor sizes between the two modalities (all <i>p</i> > 0.05). …”
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Osimertinib exacerbates immune checkpoint inhibitor-related severe adverse events by activating the IL-6/JAK/STAT3 pathway in macrophages by Yuan Li, Yanping Chen, Yuan Meng, Meng Shen, Fan Yang, Xiubao Ren

“…Enzyme-linked immunosorbent assay (ELISA) was used to detect the serum interleukin (IL)-6, alanine transaminase (ALT), ferritin, and tumor necrosis factor (TNF)-α levels. Total RNA extracted from mouse liver macrophages was analyzed by RNA-seq. …”
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UHPLC-QTOF-MS/MS profiling, molecular networking, and molecular docking analysis of Gliricidia sepium (Jacq.) Kunth. ex. Walp. stem ethanolic extract and its gastroprotective effec... by Aya A. Wafaey, Seham S. El-Hawary, Osama G. Mohamed, Sahar S. Abdelrahman, Alaa M. Ali, Ahmed A. El-Rashedy, Mohamed F. Abdelhameed, Farid N. Kirollos

“…Biological evaluations showed that GSS ethanolic extract mitigated gastric tissue injury induced by pyloric ligation, with a notable reduction in oxidative stress marker reactive oxygen species levels and inflammatory cytokines interleukin-6 and tumor necrosis factor-alpha levels. Additionally, it enhanced superoxide dismutase and inhibitor of nuclear factor kappa B alpha levels, while lowering the expression of inducible nitric oxide synthase. …”
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Suberosin attenuates rheumatoid arthritis by repolarizing macrophages and inhibiting synovitis via the JAK/STAT signaling pathway by Huan Liu, Qianwei Li, Yuehong Chen, Min Dong, Hongjiang Liu, Jiaqian Zhang, Leiyi Yang, Geng Yin, Qibing Xie

“…This study aimed to investigate the effects and potential underlying pathways of SBR on RA. Methods Tumor necrosis factor-alpha (TNF-α) induced inflammation in RA-derived fibroblast-like synoviocytes (RA-FLS), and the expression of proinflammatory mediators was assessed using q-RT PCR and ELISA after treatment with various SBR concentrations. …”
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The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer by Zheng Xu, Zheng Xu, Chengdong Qin, Binxiao Cao, Binxiao Cao, Pengcheng Ruan, Pengcheng Ruan, Mianhao Zhang, Mianhao Zhang, Guidong Chen, Guidong Chen

“…Cox regression analysis on the non-RT cohort within the BCS group identified age, tumor grade, and T stage as independent risk factors. …”
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Superior liver protection in mice fed total parenteral nutrition containing the novel lipid emulsion Vegaven as compared to a mixed-oil lipid emulsion containing fish oil by Eliana Lucchinetti, Phing-How Lou, Alessandro Quaranta, Craig E. Wheelock, Akash Chakravarty, Martin Hersberger, Stefanie D. Krämer, Michael Zaugg

“…The abundances of hepatic insulin receptor (IR), insulin receptor substrate 2 (IRS2) as well as the tyrosine phosphorylated IRS2 were higher in VEGA when compared with SMOF, fostering higher hepatic glycogen content. Tumor necrosis factor alpha and interleukin-6 (IL6) tissue concentrations were increased in livers of mice in the SMOF group and interleukin-6 (IL6) to interleukin-10 (IL10) ratios were lower in livers and epididymal white adipose tissue of mice in the VEGA group. …”
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The Association Between Neutrophil‐Percentage‐to‐Albumin Ratio (NPAR) and Mortality Among Individuals With Cancer: Insights From National Health and Nutrition Examination Survey... by Xinyang Li, Meng Wu, Minxin Chen, Rufei Liu, Qingxu Tao, Yun Hu, Jinming Yu, Dawei Chen

“…ABSTRACT Background Neutrophils interact with tumor cells, potentially exacerbating cancer progression. …”
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Identification and functional analysis of hub genes involved in deoxynivalenol-induced enterotoxicity in porcine (Sus scrofa) by Jinhua He, Geng Zhao, Mingxia Chen, Ximing Ren, Peizhi Zhu, Zhizhong Liu, Jiayi Zhou, Hanwei Chen, Chuqiao Xiao, Xiang-Guang Li

“…Further analysis revealed that the up-regulated DEGs were enriched in tumor necrosis factor, nuclear factor kappa-B, mitogen-activated protein kinases, and Janus kinase/signal transducer and activator of transcription-related signaling pathways. …”
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Ultrasonic/compound enzyme extraction, comparative characterisation and biological activity of Lonicera macranthoides polysaccharides by Mengdie Ren, Yiru Hou, Danli Peng, Hui Li, Xuxiang Zhang, Lei Qiao, XiaoShuang Wang, Yongmei Jiang, FaMing Wu, Gang Wang

“…Notably, UAE-LMP exhibited superior antioxidant, hypolipidemic, nitrite scavenging, and anti-tumor activities compared to CE-LMP. The ultrasound-assisted method enhanced the stability and bioactivity of LMP, with improved water- and oil-holding capacities and the integrity of the active groups. …”
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The Efficacy of Moxibustion on the Serum Levels of CXCL1 and β-EP in Patients with Rheumatoid Arthritis by Siyu Tao, Xue Wang, Chenxi Liao, Yan Xiong, Jie Tang, Nannan Jiang, Yuan Li, Xinyue Hu, Rouxian Shuai, Yueyue Wang, Ping Wu

“…Trial endpoints were change (∆) in symptoms, measured by Ritchie’s articular index (RAI), swollen joint count (SJC), and laboratory indicators, measured by the level of CXCL1, β-EP, tumor necrosis factor-a (TNF-α), and interleukin-1β (IL-1β). …”
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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms by Inas M. Elgharib, Fatma M. Abdelhamid, Gehad E. Elshopakey, Hatem Sembawa, Talat A. Albukhari, Waheed A. Filimban, Rehab M. Bagadood, Mohamed E. El-Boshy, Engy F. Risha

“…Cadmium toxicity caused elevated expression of liver apoptosis markers, such as tumor necrosis factor-alpha (TNF-α) and caspase-3, and inflammation. …”
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Mesenchymal stem cell-derived extracellular vesicles enriched with miR-124 exhibit anti-inflammatory effects in collagen-induced arthritis by Guo Zhonghua, He Mengyuan, Shi Dongliang, Zhang Zhongbo, Wang Lisha, Ren Bowen, Wang Yunfei, Wang Junjie, Yang Shaoxiang, Yu Hongchao

“…Cytokine levels, including interleukin (IL)-6, IL-1β, tumor necrosis factor (TNF)-α, IL-10, and transforming growth factor (TGF)-β, were measured in the joints using real-time PCR by enzyme-linked immunosorbent assay (ELISA). miR-124-hUCSC-EVs showed enrichment of miR-124. …”
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Expression and Significances of Contactin-1 in Human Gastric Cancer by Ji-Wei Yu, Sheng-Hua Wu, Rui-qi Lu, Ju-gang Wu, Xiao-Chun Ni, Gou-cai Zhou, Hai-guang Jiang, Lin-Hai Zheng, Xiao-Qiang Li, Guang-Ye Du, Bo-Jian Jiang

“…The positivity rate of VEGF-C, VEGFR-3, and CNTN-1 in primary tumor was 56.19%, 64.76%, and 58.09%. The expression of CNTN-1 significantly correlated with VEGF-C (P<0.001) and VEGFR-3 (P<0.001). …”
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Hubungan Karakteristik Penderita dengan Gambaran Sitopatologi pada Kasus Karsinoma Paru yang Dirawat di RSUP Dr. M. Djamil Padang by Metha Arsilita Hulma, Masrul Basyar, Henny Mulyani

“…<p>Abstrak<br />Karsinoma paru merupakan tumor ganas epitel primer saluran nafas terutama bronkus yang dapat menginvasi struktur jaringan di sekitarnya dan berpotensi menyebar ke seluruh tubuh. …”
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Clinical outcomes of nephroureterectomy with bladder cuff excision or radical cystectomy for distal ureteral carcinoma invaded muscle of the ureteral orifice by Pan Li, Suoshi Jing, Yindong Kang, Bin Feng, Yunxin Zhang, Hui Ding, Juan Wang, Yingru Wang, Li Yang, Zhilong Dong, Junqiang Tian, Zhiping Wang, Zizhen Hou

“…Apart from NU-RC (HR, 0.18; 95%CI: 0.08–0.44; p < 0.001) (HR, 0.28; 95%CI: 0.1–0.79; p = 0.016) and tumor volume(HR, 1.17; 95%CI: 1.06–1.29; p = 0.002) (HR, 1.21; 95%CI: 1.11–1.31; p < 0.001), which are independent prognostic factors for RFS and CSS, another independent prognostic factor for CSS is the ureteral carcinoma with renal pelvic carcinoma (HR, 4.32; 95%CI: 1.28–14.511; p = 0.018). …”
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Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer by Xiao He, Xianjie Cheng, Zhun Zhang, Lanhui Chen, Changjun Xie, Mengjie Tang

“…Efferocytosis is a process of phagocytosis of abnormal cells and is of great value in tumor research. Our study seeks to create a predictive model for BRCA using efferocytosis-related genes (ERGs) to explore the significance of efferocytosis in this disease.MethodsIn this research, Differential analysis, and univariate Cox regression were employed to identify genes linked to prognosis in BRCA patients. …”
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miR-149-3p Is a Potential Prognosis Biomarker and Correlated with Immune Infiltrates in Uterine Corpus Endometrial Carcinoma by Xiaoyuan Lu, Li Jing, Sicong Liu, Haihong Wang, Buze Chen

“…High expression of miR-149-3p in UCEC was significantly associated with age (P<0.001), histological type (P<0.001), histological grade (P<0.001), tumor invasion (P=0.014), and radiation therapy (P=0.011). …”
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Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes by Jin Lin, Ye Yu, Xuanwei Wang, Yini Ke, Chuanyin Sun, Lihuan Yue, Guanhua Xu, Bei Xu, Liqin Xu, Heng Cao, Danyi Xu, Nancy Olsen, Weiqian Chen

“…MMP-1, MMP-3, MMP-9, Interleukin-6 (IL-6), and monocyte chemoattractant protein-1 mRNA and protein levels were all decreased after treatment with iguratimod. Furthermore, tumor necrosis factor-alpha- (TNF-α-) induced expression of phosphorylated c-Jun N-terminal kinases (JNK) and P38 MAPK were inhibited by iguratimod. …”
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Rational Design of Biocompatible Ir(III) Photosensitizer to Overcome Drug‐Resistant Cancer via Oxidative Autophagy Inhibition by Mingyu Park, Jung Seung Nam, Taehyun Kim, Gwangsu Yoon, Seoyoon Kim, Chaiheon Lee, Chae Gyu Lee, Sungjin Park, Kochan S. Bejoymohandas, Jihyeon Yang, Yoon Hee Kwon, Yoo Jin Lee, Jeong Kon Seo, Duyoung Min, Taiho Park, Tae‐Hyuk Kwon

“…These findings are verified in vitro, using mass spectrometry, live cell imaging, and a model SNARE complex. The anti‐tumor efficacy of the precise lysosomal oxidation strategy is further validated in vivo with B4, engineered for red light absorbance. …”
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Effects of Stocking Density on Fatty Acid and Amino Acid Composition in Muscle, Serum Cortisol, Stress and Immune Response in Large Yellow Croaker (<i>Larimichthys crocea</i>) by Youbin Yu, Liang Wang, Wenyun Huang, Duo Yu, Qiaoxuan Sun, Mingcao Cui

“…Results of immune response analyses showed that there was a clear decrease in immunoglobulin M (IgM), complement component 4 (C4), and lysozyme (LZM) in serum, lysozyme (LZM) genes, tumor necrosis factor-alpha (TNF-α) genes and interleukin-1β (IL-1β) genes in the head kidney of large yellow croakers reared in the HD group. …”
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