DNA Amplifications and Aneuploidy, High Proliferative Activity and Impaired Cell Cycle Control Characterize Breast Carcinomas with Poor Prognosis by Harald Blegen, John S. Will, B. Michael Ghadimi, Hesed‐Padilla Nash, Anders Zetterberg, Gert Auer, Thomas Ried

“…In order to explore whether specific cytogenetic abnormalities can be used to stratify tumors with a distinctly different clinical course, we performed comparative genomic hybridization (CGH) of tumors from patients who were diagnosed with metastatic disease after an interval of less than 2 years or who remained free from distant metastases for more than 10 years. …”
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CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma by Kangkang Yang, Yushuang Wang, Yuli Jian, Bo Wang, Hao Du, Yuqing Xia, Jianlei Bi, Meihua Guo, Zhi Li, Ning Wang

“…Together, the innovative risk model using PANoptosis-associated genes effectively forecasts the tumor microenvironment and survival rates for ccRCC, offering a novel approach to the early, precise diagnosis of ccRCC and the advancement of personalized treatment strategies.…”
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Progress in Study of Low-Intensity Pulsed Ultrasound Acting on Inflammation-Related Signaling Pathways in Knee Osteoarthritis by OUYANG Hui, LIN Xingjin, WANG Jinying, SHEN Longbin, WANG Chengdong

“…The onset of KOA is associate with the metabolic imbalance of articular cartilage and the activation of cytokines, especially the high expression of interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α). They appear in multiple pathogenic signaling pathways of KOA, regulate the intracellular activity of KOA and play an important role in pathological processes such as chondrocyte destruction, extracellular matrix reduction, abnormal cartilage remodeling, subchondral ossification, and synovial inflammation. …”
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Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes by Anne-Marie L. Wegeberg, Tina Okdahl, Tina Fløyel, Christina Brock, Niels Ejskjaer, Sam Riahi, Flemming Pociot, Joachim Størling, Birgitte Brock

“…Cytokines (interleukin- (IL-) 1α, IL-4, IL-12p70, IL-13, IL-17, and tumor necrosis factor- (TNF-) α), adhesion molecules (E-selectin, P-selectin, and intercellular adhesion molecule- (ICAM-) 1), and chemokines (chemokine (C-C motif) ligand (CCL)2, CCL3, CCL4, and C-X-C motif chemokine (CXCL)10) were assessed using a Luminex multiplexing technology. …”
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Effects of Different Levels of Carbohydrates on Growth Performance, Hepatic and Intestinal Health, and Intestinal Microflora of Juvenile Pikeperch (Sander lucioperca) by Jie Zhao, Yang Liu, Zhipeng Sun, Liansheng Wang, Ze Fan, Yadan Pan, Jiamin Gao, Cuiyun Lu, Xianhu Zheng

“…In addition, proinflammatory cytokines, interleukin 1 beta (il1-β), interleukin 8 (il8), and tumor necrosis factor beta (tnf-β), in the liver and intestine elevate and anti-inflammatory cytokines, interleukin 10 (il10) and transforming growth factor beta (tgf-β), decrease with increasing dietary carbohydrate levels. …”
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The effect of absorbable collagen suture for oral implant repair on wound healing and inflammation factors of gingival crevicular fluid by Jingjing Feng, Qiaolong Yu, Xiaoqing Liu

“…The incision healing time, postoperative pain degree, incision healing grade, patient satisfaction, and the levels of tumor necrosis factor-a (TNF-a), interleukin-8 (IL-8) and interleukin-6 (IL-6) in gingival crevicular fluid were compared between the two groups. …”
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Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism by Xiao-Qing Song, Tian-Jian Yu, Yang Ou-Yang, Jia-Han Ding, Yi-Zhou Jiang, Zhi-Ming Shao, Yi Xiao

“…Clinically, pharmacological inhibition of the FLAD1/LSD1/SREBP1 axis effectively suppresses FLAD1-induced tumor progression. Moreover, LSD1 inhibitor enhances the therapeutic effect of doxorubicin and sacituzumab govitecan (SG). …”
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Network Pharmacology and Molecular Docking Study on the Mechanism of the Therapeutic Effect of Strychni Semen in NSCLC by He Geng, Yujie Xue, Binghua Yan, Zhaoxue Lu, Hengjin Yang, Peng Li, Jundong Zhou

“…Abstract Strychni Semen, characterized by its bitter taste and warm properties, has been confirmed to possess anti-tumor properties. However, the molecular mechanism of Strychni Semen in treating non-small cell lung cancer (NSCLC) needs further study. …”
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Lymphopenia Is Associated with Gross Target Volumes and Fractions in Hepatocellular Carcinoma Patients Treated with External Beam Radiation Therapy and Also Indicates Worse Overall... by Hai-Ge Zhang, Ping Yang, Tao Jiang, Jian-Ying Zhang, Xue-Juan Jin, Yong Hu, Jing Sun, Shi-Suo Du, Zhao-Chong Zeng

“…Associations between gross tumor volumes (GTVs) and radiation-associated parameters with lymphocyte nadir were evaluated by Pearson/Spearman correlation analysis and multiple linear regression. …”
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Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma by Qiuni Chen, Lei Xu, Chuanyang Lu, Yujie Xue, Xue Gong, Yuye Shi, Chunling Wang, Liang Yu

“…Previous studies have found that cyclin-dependent kinase 1(CDK1) are related to tumor growth and metastasis. However, the role of CDK1 in DLBCL is exclusive. …”
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Long-Term Intracranial Progression-Free Survival in Lung Cancer Brain Metastases Extended Beyond 50 Months with Gubenxiaoyi Formula (GBXY): A Groundbreaking Case Study by Zhengzheng Yang, Haiming Li, Lei Chen, Shujiao Li, Dong Chen, Taicheng Lu, Tongjing Ding, Ruiyang Han, Peiyu Cheng, Xiaomin Wang

“…Conclusion These results demonstrate that in patients with lung cancer brain metastases (BM) unresponsive to standard treatments, GBXY not only has the potential to effectively prolong IPFS and decelerate cognitive decline, but may also contribute to a reduction in intracranial tumor burden. This suggests that GBXY could be a promising therapeutic option that warrants further investigation.…”
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Caracterización de pacientes con esplenopatía quirúrgica no traumática by Jan González Ramos, Zoe Quintero Delgado, Annia Quintana Marrero

“…<br /><strong>Conclusiones:</strong> se operaron 32 pacientes del bazo por causa no traumática, 1 paciente con esplenoptosis o bazo aberrante y un paciente con un tumor esplénico. La esplenectomía parcial se realizó en el 100 % de los pacientes con β talasemia. …”
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B-CLL with negative 18F-FDG PET/CT and intensive solitary lesion on PSMA PET/CT mimicking prostate cancer bone metastases by Theresa Jung, Daniel Neureiter, Gregor Schweighofer-Zwink, Gundula Rendl, Christian Pirich, Mohsen Beheshti

“…Both 68Ga-PSMA-11 and 2-(3-(1-carboxy-5-((6-(18f)fluoro-pyridine-3-carbonyl)-amino)-pentyl)-ureido)-pentanedioic acid (18F-DCFPyL) PET/CT, which were performed for prostate cancer staging and re-staging in about 1 year interval, showed focal uptake in the primary prostate tumor as well as an intense focal lesion in L2, suggestive of bone metastasis. 18F-FDG PET/CT scans performed before and after PSMA PET/CT examinations showed no abnormal uptake related to oesophageal and/or B-CLL. …”
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Mirizzi Syndrome: Diagnosis and Management of a Challenging Biliary Disease by Gennaro Clemente, Andrea Tringali, Agostino M. De Rose, Elena Panettieri, Marino Murazio, Gennaro Nuzzo, Felice Giuliante

“…Preoperative diagnosis of Mirizzi syndrome was achieved in 11 patients, while 6 had a diagnosis of gallbladder cancer and 1 of Klatskin tumor. Seventeen patients underwent surgery, including cholecystectomy in 8 cases, bile duct repair over T-tube in 3 cases, and hepaticojejunostomy in 4 cases. …”
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Expression of CSTF2 in oral squamous cell carcinoma and its relationship with immune infiltration and poor prognosis by Zumulaiti Aierken, Muertiza Muhetaer, Zhang Lei, Ainiwaerjiang Abudourousuli, Ainiwaerjiang Abudourousuli

“…Cleavage Stimulation Factor Subunit 2 (CSTF2) is known to influence tumor development across multiple cancer types. However, its specific association with patient prognosis and immune cell infiltration in OSCC remains insufficiently understood.MethodsTo assess the expression levels and prognostic implications of CSTF2 in OSCC, comprehensive data were acquired from The Cancer Genome Atlas (TCGA) and subsequently normalized. …”
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Nomogram based on dual-energy computed tomography to predict the response to induction chemotherapy in patients with nasopharyngeal carcinoma: a two-center study by Huanhuan Ren, Junhao Huang, Yao Huang, Bangyuan Long, Mei Zhang, Jing Zhang, Huarong Li, Tingting Huang, Daihong Liu, Ying Wang, Jiuquan Zhang

“…The clinical and DECT-derived parameters of tumor lesions were calculated to predict the response. …”
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Targeting Cytokine-Mediated Inflammation in Brain Disorders: Developing New Treatment Strategies by Rahul Mallick, Sanjay Basak, Premanjali Chowdhury, Prasenjit Bhowmik, Ranjit K. Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

“…Pro-inflammatory cytokines such as interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) cause neuroinflammation, alter brain function, and accelerate disease development. …”
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Functional Analysis and Experimental Validation of the Prognostic and Immune Effects of the Oncogenic Protein CDC45 in Breast Cancer by Zhang JN, Li LW, Cao MQ, Liu X, Yi ZL, Liu SS, Liu H

“…This study investigates its role in breast cancer (BC) and its impact on tumor progression.Methods: We utilized the GEO database to screen differentially expressed genes (DEGs) and conducted enrichment analysis on these genes. …”
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The Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma Treated with Lenvatinib Combined with PD-1 Inhibitors by Xin Y, Liu N, Peng G, Huang X, Cao X, Zhou X

“…The AUC value of nomogram based on baseline SIRI, PNI, and tumor distribution in predicting the 6-,12- and 18-month PFS of patients was significantly higher than that of traditional BCLC stage, and its prediction performance was substantially better than that of BCLC stage system (C-index, 0.730 vs 0.535).Conclusion: The baseline SIRI could be used as a potential non-invasive biomarker to predict the efficacy and survival benefit of immune combination therapy for HCC. …”
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The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression by Yayun Zheng, Xue Ma, Dongmei Su, Yue Zhang, Lin Yu, Fangfei Jiang, Xue Zhou, Ying Feng, Fang Ma

“…In this review, we aim to discuss the similarities and differences between Siglec7 and Siglec9 and analyze their functions in virus infection and tumour progression in order to develop better anti-viral and anti-tumor immunotherapy in the future.…”
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