Eccentric exercise‐induced muscle damage and inflammation in conjunction with high‐altitude decompression in adults by Frode Gottschalk, Mikael Gennser, Mattias Günther, Ola Eiken, Antonis Elia

“…Creatine kinase (CK) and myoglobin were used to assess muscle damage, while interleukin‐6 (IL‐6), tumor necrosis factor alpha (TNF‐α), C‐reactive protein (CRP), and fibrinogen were used to evaluate inflammation. …”
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Association between cytokines and progression-free survival in ovarian cancer following CRS/HIPEC treatment by Chao-Yu Chen, Ting-Yao Wang, Jing-Lan Liu, Yu-Che Ou, Li-Wen Lee, Chien-Hui Hung, Chuan-Pin Lee, Jrhau Lung

“…IHC analysis showed a trend towards worse PFS within the first year for patients with MCP-1 expression in tumor tissue (HR: 3.252, p = 0.264). Conclusion Cytokines, particularly MCP-1, may help predict PFS following CRS/HIPEC in EOC patients and could inform postoperative treatment decisions. …”
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Astragaloside IV attenuates cadmium induced nephrotoxicity in rats by activating Nrf2 by Yuchen Li, Jiayi Zhou, Tianxin Zhang, Xiaocong Li, Cheng Wu, Ziyi Zhao, Jianyuan Tang, Xiaoyu Tan, Qiongying Hu, Wenhao Liao

“…Astragaloside IV (AS-IV) is a saponin isolated from Astragalus membranaceus with good antioxidant, anti-inflammatory and anti-tumor properties. In this study, HK2 cells and rat model were utilized to explore the protective effect of AS-IV against cadmium chloride-induced oxidative stress-induced apoptosis. …”
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Research on the Mechanism of Mannose Oligosaccharide Enhancing the Inhibitory Effect of Bifidobacterium breve on the Growth of Fusobacterium nucleatum by Xuyan ZHANG, Ruijie LIU, Bo ZHAO, Xiaoxi XU

“…In conclusion, the combination of mannose oligosaccharides and Bifidobacterium breve may be used as a safe and effective biological control inhibitor of Fusobacterium nucleatum, which may provide a safer and more effective method for the prevention and adjuvant treatment of colorectal cancer and other tumor diseases.…”
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MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells by Chao Sun, Lai-gang Huang, Bing Leng, Yanting Guo, Chen Chen, Ruijie Lv, Yan Dong, Tian-tian Gao, De-qing Sun

“…Western blot, qRT-PCR, Co-immunoprecipitation, and luciferase reporter analysis were performed to explore the associated mechanisms. We established mouse tumor xenografts and mouse metastasis models to explore the role of miR-32-5p and anti-miR-32-5p in vivo. …”
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A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation by Shuhua Luo, Menglin Tang, Lei Du, Lina Gong, Jin Xu, Youwen Chen, Yabo Wang, Ke Lin, Qi An

“…Blood analysis after ECC showed significant increases in levels of tumor necrosis factor α, interleukin-6, and neutrophil elastase in plasma, lung, and renal tissues, as well as increases in plasma creatinine and cystatin C and decreases in the oxygenation index. …”
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Prognostic Value of Combination of Pretreatment Red Cell Distribution Width and Neutrophil-to-Lymphocyte Ratio in Patients with Gastric Cancer by Danyang Zhou, Ying Wu, Zhenyu Lin, Liangliang Shi, Lei Zhao, Tao Liu, Dandan Yu, Tao Zhang

“…Moreover, high RDW + NLR was strongly related to age, tumor location, TNM stage, CA125, and CA199. In a subgroup analysis for patients with advanced gastric cancer (AGC), we observed that the level of RDW + NLR was markedly associated with OS and PFS. …”
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Illuminating the impact of CD38-induced adenosine formation in B-cell lymphoma by Shams ElDoha Galal ElDin Zaiema, Heba Mohamed Saber Hafez, Diaa El-Din Moussa Sherif Abou El-Ela, Rawda Ahmed Alaaeldin Ahmed Mohamed Saad

“…Abstract The expression of CD38 by cancer cells may mediate an immune-suppressive effect by producing Extracellular Adenosine (ADO) acting through G-protein-coupled cell surface receptors on cellular components and tumor cells. This can increase PD-1 expression and interaction with PD-L1, suppressing CD8 + cytotoxic T cells. …”
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Un caso atípico de neoplasia de pulmón by Mislay Rodriguez Garcia, Martha Campos Muñoz, Daniela De la Caridad Rodriguez Campos, Osmel Daniel Chacon Reyes, Joel Reynaldo Chiang Borges

“…Introducción: El cáncer de pulmón se considera el tumor maligno que más muertes produce en el mundo, por encima de otros cánceres y en el 90 % de los casos se diagnostica en estadios avanzados. …”
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Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents by Hafez Hend N., Alsalamah Sulaiman A., El-Gazzar Abdel-Rhman B. A.

“…Most of the newly synthesized compounds were evaluated for their in vitro activity against three human tumor cell lines, namely, liver cancer (HepG-2), colon cancer (HT-29) and lung cancer (NCI-H460), using doxorubicin as standard. …”
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Adipocytokines in Rheumatoid Arthritis: The Hidden Link between Inflammation and Cardiometabolic Comorbidities by Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Cipriani, Roberto Giacomelli

“…Remarkably, some well-known pathogenic proinflammatory mediators in RA, such as interleukin-1β (IL-1β) and tumor necrosis factor (TNF), may play a pivotal role in the development of CVD. …”
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Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota by Kai Kang, Yue Sun, Dan Pan, Bing Chang, Li-Xuan Sang

“…Moreover, enzyme-linked immunosorbent assay (ELISA) analysis of LPL cells revealed that the level of interleukin- (IL-) 6, IL-12p70, IL-1β, tumor necrosis factor- (TNF-) α, interferon- (IFN-) γ, IL-21, and IL-17A was increased, while IL-10 was reduced, in the chronic colitis group compared to the control group, but the levels of all these factors were restored after NAM treatment. …”
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Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes by Cherilyn Uhm, Jianlei Gu, Weina Ju, Stephanie Pizzella, Hande Oktay, Joyce Yao-Chun Peng, Sararose Guariglia, Yong Liu, Hongyu Zhao, Yong Wang, Ramkumar Menon, Nanbert Zhong

“…In pPROM, heightened inflammation, oxidative stress, and vascular dysregulation with key pathways including tumor necrosis factor signaling, matrix metalloproteinase activation, and integrin-mediated cell adhesion, highlighted an invasive EVT profile potentially driven by hypoxic conditions and immune cell recruitment. …”
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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…Poly ADP-Ribose Polymerase inhibitors (PARPi) are novel anti-cancer agents that induce DNA damages and cause cell death in tumor cells with impaired DNA repair, known as the synthetic lethality concept. …”
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Effect of Stocking Density on Stress-Related Gene Expression of Pacific White Shrimp (Litopenaeus vannamei) Infected with Infectious Myonecrosis Virus (IMNV) by Moch. Nurhudah, Nur Komariah Baladrat, Sinung Rahardjo, Heny Budi Utari, Putu Angga Wiradana

“…The upregulated genes were lectin and translationally controlled tumor protein (TCTP), while the downregulated gene was Toll Receptor. …”
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Observation on Therapeutic Effect of Neuromuscular Electrical Stimulation and Rehabilitation Training on Dysphagia Patients Caused by Different Brain Injuries and Effect on Their H... by Yan LI

“…There were 17 dysphagia patients due to brain tumor oppression of nerve were recruited in group A, 14 dysphagia patients due to cerebral thrombosis were recruited in group B, 14 dysphagia patients due to parkinsonian syndrome were recruited in group C, and 10 dysphagia patients due to cerebral palsy were recruited in group D. …”
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Levo-Tetrahydropalmatine Attenuates Bone Cancer Pain by Inhibiting Microglial Cells Activation by Mao-yin Zhang, Yue-peng Liu, Lian-yi Zhang, Dong-mei Yue, Dun-yi Qi, Gong-jian Liu, Su Liu

“…The present study is to investigate the analgesic roles of L-THP in rats with bone cancer pain caused by tumor cell implantation (TCI). Methods. Thermal hyperalgesia and mechanical allodynia were measured at different time points before and after operation. …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer by Jie Peng, Jiaao Sun, Youfeng Yu, Qihang Yuan, Yong Zhang

“…Abstract As one of the most destructive and invasive cancers, pancreatic cancer exhibits complex tumor heterogeneity, which has been a major challenge for clinicians in terms of patient treatment and prognosis. …”
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Long-Term Survival in a Patient with Multiple Brain Metastases from Small-Cell Lung Cancer Treated with Gamma Knife Radiosurgery on Four Occasions: A Case Report by Ameer L. Elaimy, Sudheer R. Thumma, Andrew F. Lamm, Alexander R. Mackay, Wayne T. Lamoreaux, Robert K. Fairbanks, John J. Demakas, Barton S. Cooke, Christopher M. Lee

“…Furthermore, multiple repeat GKRS procedures provided this patient with high levels of local tumor control, which in combination with a stable primary cancer led to an extended period of survival and a highly functional life. …”
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MicroRNAs in the DNA Damage/Repair Network and Cancer by Alessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Davide Vecchiotti, Daria Capece, Francesca Zazzeroni, Edoardo Alesse

“…Cancer is a multistep process characterized by various and different genetic lesions which cause the transformation of normal cells into tumor cells. To preserve the genomic integrity, eukaryotic cells need a complex DNA damage/repair response network of signaling pathways, involving many proteins, able to induce cell cycle arrest, apoptosis, or DNA repair. …”
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