Investigating proteogenomic divergence in patient-derived xenograft models of ovarian cancer by Jesenia M. Perez, Jolene M. Duda, Joohyun Ryu, Mihir Shetty, Subina Mehta, Pratik D. Jagtap, Andrew C. Nelson, Boris Winterhoff, Timothy J. Griffin, Timothy K. Starr, Stefani N. Thomas

“…Abstract Within ovarian cancer research, patient-derived xenograft (PDX) models recapitulate histologic features and genomic aberrations found in original tumors. However, conflicting data from published studies have demonstrated significant transcriptional differences between PDXs and original tumors, challenging the fidelity of these models. …”
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Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i> by Qinghao Meng, Anna Hu, Weiyu Xiao, Robert P. Borris, Hyun-Min Kim

“…LC-MS analysis revealed 31 potential anti-tumor compounds, supporting the extract’s cytotoxic properties. …”
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NIR-II-excited off-on-off fluorescent nanoprobes for sensitive molecular imaging in vivo by Yufu Tang, Yuanyuan Li, Chunxu He, Zhen Wang, Wei Huang, Quli Fan, Bin Liu

“…Due to its low background, a blind study employing our probes could identify female mice with orthotopic liver tumors with 100% accuracy from mixed subjects of healthy and tumor mice, and implemented sensitive locating of early orthotopic liver tumors with sizes as small as 4 mm. …”
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Association of Serum Adiponectin with Intima Media Thickness of Dorsalis Pedis Artery and Macroangiopathy in Type 2 Diabetes by Tao Chen, Mei Tu, Lihua Huang, Youping Zheng

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Case report: A rare case of delayed drug-induced hyponatremia in recurrent upper tract urothelial carcinoma following GC and Tislelizumab treatment by Zhi-Jie Wang, Zhi-Jie Wang, Ying-Fang Nie, Shi-Bing Liang, Shi-Bing Liang, Shi-Bing Liang, Jing Zhou, Shu-Lan Hao, Li-Kun Liu

“…Now, she is on 21-day Tislelizumab maintenance with a stable tumor status. Low-dose continuous Cisplatin may suit patients with borderline or mildly abnormal renal function (GFR: 40-60mL/min) better than single full-dose use. …”
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Electroacupuncture Therapy Effectively Protects the Rat Brain after Intracerebral Hemorrhage by Li Huang, Xuehui Fan, Yao Chen, Heng Lin, Xiaoqian Jiang, Chaoxian Yang

“…The serum myelin basic protein (MBP), neuron-specific enolase (NSE), calcium-binding protein B (S100B), and tumor necrosis factor-α (TNF-α) concentrations were examined with ELISA. …”
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Deep Learning and Radiomics in Triple-Negative Breast Cancer: Predicting Long-Term Prognosis and Clinical Outcomes by Cheng C, Wang Y, Zhao J, Wu D, Li H, Zhao H

“…Chen Cheng,1,&ast; Yan Wang,2,3,&ast; Jine Zhao,4,&ast; Di Wu,1 Honge Li,5 Hongyan Zhao1 1Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, Lianyungang, 222004, People’s Republic of China; 2Department of Ultrasound, Lianyungang Municipal Oriental Hospital, Lianyungang, 222046, People’s Republic of China; 3Department of Ultrasound, Xuzhou Medical University Affiliated Hospital, Lianyungang, Jiangsu, 222061, People’s Republic of China; 4Department of Ultrasound, Donghai County People’s Hospital, Lianyungang, Jiangsu, 222300, People’s Republic of China; 5Department of Ultrasound, the First People’s Hospital of Lianyungang, Lianyungang, Jiangsu, 222061, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hongyan Zhao, Department of Ultrasound, Lianyungang Traditional Chinese Medicine Hospital, No. 160, Chaoyang Middle Road, Haizhou District, Lianyungang, 222004, People’s Republic of China, Tel +86 0518-85574003, Email zhaohongyanzhy01@126.comAbstract: Triple-negative breast cancer (TNBC) is a unique breast cancer subtype characterized by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression in tumor cells. TNBC represents about 15% to 20% of all breast cancers and is aggressive and highly malignant. …”
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Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization by Guokun Liu, Xuan Du, Li Xiao, Qing Zeng, QianLing Liu

“…Accumulating evidence has elucidated the biological function of lncRNAs in various tumors. FGD5 antisense RNA 1 (FGD5-AS1) is identified as a significant tumor regulator in malignancies. …”
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C-MCG: Synthesis, Uptake Selectivity, and Primate PET of a Probe for Glutamate Carboxypeptidase II (NAALADase) by Martin G. Pomper, John L. Musachio, Jiazhong Zhang, Ursula Scheffel, Yun Zhou, John Hilton, Atul Maini, Robert F. Dannals, Dean F. Wong, Alan P. Kozikowski

“…Imaging of glutamate carboxypeptidase II (GCP II), also known as N -acetylated α-linked l -amino dipeptidase (NAALADase), may enable study of glutamatergic transmission, prostate cancer, and tumor neovasculature in vivo. Our goal was to develop a probe for GCP II for use with positron emission tomography (PET). …”
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Factors Requiring Adjustment in the Interpretation of Serum Carcinoembryonic Antigen: A Cross-Sectional Study of 18,131 Healthy Nonsmokers by Hae Yeon Kang, Eun Kyung Choe, Kyu Joo Park, Young Lee

“…Serum carcinoembryonic antigen (CEA) is a well-known tumor marker for colorectal adenocarcinoma. However, CEA levels can be influenced by various nonmalignant conditions. …”
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PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model by Weimin Zhu, Rui Bao, Xiaohua Fan, Tianzhu Tao, Jiali Zhu, Jiafeng Wang, Jinbao Li, Lulong Bo, Xiaoming Deng

“…Anti-PD-L1 antibody administration decreased ALT and AST release in CLP mice, decreased the levels of tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 mRNA in liver after sepsis challenge. …”
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Identificación del riesgo de trombosis en pacientes con padecimientos oncológicos ambulatorios en quimioterapia by Maylín Jiménez Abraham, Julio Dámaso Fernández Águila, Ana Lourdes Vasallo Díaz, Dayana Calzada Urquiola

“…Las variables analizadas fueron: edad, sexo, sitio del tumor primario, conteo de plaquetas previo a la quimioterapia, niveles de hemoglobina sérica, uso de eritropoyetina, conteo leucocitario previo a la quimioterapia e índice de masa corporal. …”
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Nursing of a lung cancer patient with cough treated by Traditional Chinese Medicine ointment combined with acupoint sticking therapy (中药膏摩联合穴位贴敷疗法治疗1例肺癌相关性咳嗽患者的护理体会)... by WANG Xingyuan (王兴元), LIU Shuhong (刘书红), ZHANG Zhonghua (张中华)

“…Based on the concept of warming and obstruction-removing as tonifying therapy and green nursing of tumor, the patient was treated with the combination therapy of Traditional Chinese Medicine ointment on bladder meridian (Feishu acupoint, Gaohuang acupoint) and acupoint sticking on Ren Channel (Tiantu acupoint) and bladder meridian (Feishu acupoint). …”
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Clinicopathologic Characteristics and Long-Term Outcome of Gastric Cancer Patients with Family History: Seven-Year Follow-Up Study for Korean Health Check-Up Subjects by Jooyoung Lee, Su Jin Chung, Ji Min Choi, Yoo Min Han, Joo Sung Kim

“…There were no significant differences in tumor characteristics according to FHx of GC. However, preexisting adenoma was more frequent in patients with FHx than in those without FHx (14.5% vs. 6.3%, p=0.035). …”
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Intra-Articular Injection of Human Synovial Membrane-Derived Mesenchymal Stem Cells in Murine Collagen-Induced Arthritis: Assessment of Immunomodulatory Capacity In Vivo by Minglu Yan, Xin Liu, Qiujie Dang, He Huang, Fan Yang, Yang Li

“…Intra-articular SM-MSC injection ameliorated the clinical and histological severity of arthritis. Decrease in tumor necrosis factor-α, interferon-γ, and interleukin- (IL-) 17A and increase in IL-10 production were observed after SM-MSC treatment. …”
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Protocol to study the impact of breast cancer on colonization resistance of mouse microbiota using network node manipulation by Ana Laura Cano-Argüelles, Alejandra Wu-Chuang, Lourdes Mateos-Hernandez, Lianet Abuin-Denis, Apolline Maitre, Janet Avellanet, Arlem García, Dasha Fuentes, Alejandro Cabezas-Cruz

“…Here, we describe the procedures for tumor cell production and inoculation and 16S rRNA data processing. …”
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Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects by Takashi Kobayashi, Takaomi Kessoku, Michihiro Iwaki, Asako Nogami, Masato Yoneda, Satoru Saito, Yoshie Yamana, Yosuke Nishitani, Hiroshige Kuwahara, Atsushi Nakajima

“…Messenger RNA levels for the pro-inflammatory cytokines, interleukin-1 beta, and tumor necrosis factor-alpha showed no significant changes in the small intestine; however, their expressions significantly decreased in the colon. …”
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CD163, a novel receptor for TNF, was revealed in situ by proximity ligation assay by Alexandre Cousin, Myriam Oger, Aymar de Jenlis, Audrey Lejart, Laure Barbier, Diane Riccobono, Xavier Holy, Anne-Laure Favier, Krisztina Nikovics

“…In an inflamed porcine lung model, we demonstrated the efficacy of PLA in detecting interactions between tumor necrosis factor (TNF) and its receptors TNFR1 and TNFR2. …”
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Prognostic Value of Metastatic No.8p LNs in Patients with Gastric Cancer by Dong-Jiao Guo, Kun Yang, Wei-Han Zhang, Xiao-Long Chen, Xin-Zu Chen, Bo Zhang, Zong-Guang Zhou, Jian-Kun Hu

“…Compared with other 260 cases, these patients suffered morphologically larger tumor (P=0.003), node stage (P=0.000), and metastatic stage (P=0.000). …”
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Transcriptome profiling revealed multiple circadian rhythm-related genes associated with common gynecological cancers by Lan Peng, Meiping Jiang, Kangming Li, Shuhui Yu, Chunfang Zhao, Lan Zhang, Lan Li

“…Moreover, function and tumor micro-environment (TME) analyses in different risk groups were performed for further study of the potential mechanism of CC. …”
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