A comparative analysis of toxicity and treatment outcomes of adaptive radiotherapy and intensity-modulated radiotherapy in cervical cancer by Xiaohan Liu, Wei Tian, Anli Dai, Hui Li, Mei Zhu, Mengsi Zeng, Ronghua Feng, Zhenyu Zhang, Xiaosong Jiang, Yu Wen, Tao Wu, Zemin Xiao

“…Fifty-six patients underwent offline ART, defined as the reduction of the gross tumor volume (GTV) by at least 30% after 30 Gy of radiotherapy, followed by a modified treatment plan for the second-stage. …”
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[18F]-(2S,4R)4-Fluoroglutamine PET Imaging of Glutamine Metabolism in Murine Models of Hepatocellular Carcinoma (HCC) by Youngho Seo, Miranda C. Craig, Stephanie T. Murphy, Jinjin Feng, Xin Chen, Mariia Yuneva

“…Influx rate constants were significantly higher for MYC tumors (K1=0.374±0.133) than for MET tumors (K1=0.141±0.058) under fasting conditions (P=0.0002). …”
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Unveiling the potential of spirulina algal extract as promising antibacterial and antibiofilm agent against carbapenem-resistant Klebsiella pneumoniae: in vitro and in vivo study by Mohamed I. Selim, Tarek El-banna, Fatma Sonbol, Walaa A. Negm, Engy Elekhnawy

“…Using immunohistochemical investigations, the percentage of the immunoreactive cells significantly decreased after using monoclonal antibodies of the tumor necrosis factor-alpha and interleukin six. …”
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A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies by Reza Panahizadeh, Padideh Panahi, Vahid Asghariazar, Shima Makaremi, Ghasem Noorkhajavi, Elham Safarzadeh

“…Challenges include resistance mechanisms, immunosuppressive tumor environments, and inconsistent results from combination therapies. …”
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Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs by Abbas A Hamzah, Zainab I Ibrahim

“…The blood samples were collected from all animal groups at day zero before pneumoniae induction and 3, 6, and 14 days post infection  for total and differential white blood cell count ‎(WBCs) and tumor necrosis factor-alpha (TNF-α) assessments. …”
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Risk Factors Associated with Breast Cancer in Women in a Health Area by Naifi Hierrezuelo Rojas, Mileidy Cordoví Hierrezuelo, Naiovis Neira Hierrezuelo

“…<strong>Foundation:</strong> breast cancer is the most common malignant tumor among women around the world. In Cuba, it continues to be the neoplasia most diagnosed in women, which is why it is important to determine the associated risk factors. …”
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Regular Voluntary Exercise Potentiates Interleukin-1β and Interleukin-18 Secretion by Increasing Caspase-1 Expression in Murine Macrophages by Ken Shirato, Kazuhiko Imaizumi, Takuya Sakurai, Junetsu Ogasawara, Hideki Ohno, Takako Kizaki

“…Peritoneal macrophages from VE mice secreted considerably higher amounts of interleukin- (IL-) 1β and IL-18 than did cells from sedentary control (SC) mice in the presence and absence of LPS, although tumor necrosis factor-α and IL-10 secretion were comparable between both groups. …”
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The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis by Mingfa Liu, Zhennan Xu, Zepeng Du, Bingli Wu, Tao Jin, Ke Xu, Liyan Xu, Enmin Li, Haixiong Xu

“…Glioma is the most common malignant tumor in the central nervous system. This study aims to explore the potential mechanism and identify gene signatures of glioma. …”
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DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations by Jason Sheng Li, Karen Riggins, Li Yang, Chaorong Chen, Patricia Castro, Wedad Alfarkh, Neda Zarrin-Khameh, Michael E. Scheurer, Chad J. Creighton, Benjamin Musher, Wei Li, Lanlan Shen

“…Results We show the epigenetic landscape of these EOCRC patients differs from that of late-onset colorectal cancer patients, and methylation canyons in EOCRC tumor tissue preferentially overlapped genes in cancer-related pathways. …”
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Evaluation of EGFR-TKIs and ICIs treatment stratification in non-small cell lung cancer using an encrypted multidimensional radiomics approach by Xingping Zhang, Xingting Qiu, Yue Zhang, Qingwen Lai, Yanchun Zhang, Guijuan Zhang

“…Additionally, our findings suggest that the efficacy of EGFR-TKIs and ICIs therapy may not depend on detecting a singular tumor feature or cell type. Conclusion The proposed method effectively balances the level of evidence with privacy protection, enhancing the study’s validity and security. …”
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EUS-FNA Diagnosis with Core Biopsy of Pancreatic Metastases from Primary Breast Cancer by Samuel Galante Romanini, Juan Pablo Román Serrano, Juliana Silveira Lima de Castro, Isabela Trindade Torres, Alex Ingold, André Lucchiari Borini, Luiz Augusto Sanches Zulske, Maria Bruna Feitosa Matias, Jéssica Said de Marchi, José Andrés Sanchez Pulla, José Celso Ardengh

“…The pancreas as a site of metastasis of other primary tumors is a rare event. Pancreatic metastases may occur years after the start of treatment of a neoplasm of another organ or may be the initial manifestation of an unidentified primary tumor. …”
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The effect of interferon alpha administration on cytokine levels in sheep by Devran Coşkun, Merve İder, Mustafa Sedat Arslan, Rahmi Canbar, Enver Yazar

“…2a administration on serum tumor necrosis factor (TNF)-?, interleukin (IL)-6 and IL-10 levels in healthy sheep. …”
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The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
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The trends of lung cancer burden in BRICS from 1990 to 2021 and its projection to 2035 by Yifan Wang, Jingwen Zhu, Shaoqiang Wang, Jihong Zhou

“…BackgroundLung cancer has become the malignant tumor with the highest morbidity and mortality in the world. …”
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Associations of Salivary BPIFA1 Protein in Chronic Periodontitis Patients with Type 2 Diabetes Mellitus by Yue Guo, Lin-Na Guo, Jun-Fei Zhu, Chen-Yi Tang, Yun-Zhi Feng, Hou-De Zhou

“…We also detected full-mouth clinical periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), bleeding index (BI), and plaque index (PLI). Salivary BPIFA1, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) concentrations were also detected. …”
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Papillary Carcinoma of Breast: Clinicopathological Characteristics, Management, and Survival by Bushra Rehman, Anam Mumtaz, Barka Sajjad, Namra Urooj, Sameen Mohtasham Khan, M. Toqeer Zahid, Huma Mannan, M. Zulqarnain Chaudhary, Amina Khan, M. Asad Parvaiz

“…The mean age at presentation was 61 years; the mean tumor size was 33 mm. The frequency of each histological type was as follows: IPC (n=22/38%), EPC (n=22/38%), SPC (n=12/20.6%), and papillary DCIS (n=2/3.4%). …”
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Immunomodulatory effects of fucoidan extracted from Sargassum fusiforme in RAW 264.7 macrophages by Serim Park, Yunjin Choi, Seonmi Ji, Seonghui Kim, Seon Yeong Ji, Yung Hyun Choi, You-Jin Jeon, Bomi Ryu, Jun-Geon Je, Suengmok Cho

“…Additionally, SFF upregulated the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), while promoting the secretion of cytokines such as tumor necrosis factor-α, interleukin (IL)-6, and IL-1β in a dose-dependent manner. …”
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Toxic effects of polystyrene nanoplastics on MDA-MB-231 breast cancer and HFF-2 normal fibroblast cells: viability, cell death, cell cycle and antioxidant enzyme activity by Hanie Sadeghinia, Parichehr Hanachi, Reihaneh Ramezani, Samaneh karbalaei

“…Additionally, the study explores the anti-tumor effects and apoptosis induction by PS-NH2. …”
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Scoulerine promotes cytotoxicity and attenuates stemness in ovarian cancer by targeting PI3K/AKT/mTOR axis by Wang Fang, Zhang Yang, Pang Rui, Shi Shaohong, Wang Ran

“…In vivo studies revealed a substantial decrease in tumor mass and volume after scoulerine treatment. …”
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Selenium–Chondroitin Sulfate Nanoparticles Inhibit Angiogenesis by Regulating the VEGFR2-Mediated PI3K/Akt Pathway by Xia Zheng, Xiaofei Liu, Zhuo Wang, Rui Li, Qiaoli Zhao, Bingbing Song, Kit-Leong Cheong, Jianping Chen, Saiyi Zhong

“…In our previous study, CS was used as a template for the synthesis of seleno-chondroitin sulfate (SeCS) through the redox reaction of ascorbic acid (Vc) and sodium selenite (Na₂SeO₃) and we found that SeCS could inhibit tumor cell proliferation and invasion. However, its effect on angiogenesis and its underlying mechanism are unknown. …”
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