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7861
ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP
Published 2025-01-01“…In this study, we observed an elevated expression of ALDOA in human CRC tissues and a positive correlation of elevated ALDOA expression with tumor size, invasion depth, LNM, and TNM stage. Kaplan–Meier analysis revealed that elevated ALDOA levels correlated with a poor prognosis in CRC patients with stage I-III, whereas the prognosis tends to be favorable in patients with advanced CRC. …”
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7862
Podocyte-related biomarkers' role in evaluating renal toxic effects of silver nanoparticles with the possible ameliorative role of resveratrol in adult male albino rats
Published 2025-06-01“…Upregulation of interleukin 1 beta, tumor necrosis factor-alpha, and monocyte chemoattractant protein-1 gene expressions with downregulation of nephrin and podocin gene expressions in renal tissues were also observed. …”
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7863
Expression of Angiogenesis Regulatory Proteins and Epithelial-Mesenchymal Transition Factors in Platelets of the Breast Cancer Patients
Published 2014-01-01“…Platelets play a role in tumor angiogenesis and growth and are the main transporters of several angiogenesis regulators. …”
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7864
Angiogenic Response to Major Lung Resection for Non-Small Cell Lung Cancer with Video-Assisted Thoracic Surgical and Open Access
Published 2012-01-01“…Angiogenic factors following oncological surgery is important in tumor recurrence. Vascular endothelial growth factor (VEGF), angiopoietin 1 (Ang-1), Ang-2, soluble VEGF-receptor 1 (sVEGFR1) and sVEGFR2 may influence angiogenesis. …”
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7865
Rotationplasty for Unplanned Fixation of Pathological Fracture Distal Femoral Osteosarcoma
Published 2020-01-01“…Adjuvant chemotherapy was given after a free margin with good tumor necrosis which was achieved as shown in the pathological study. …”
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7866
Machine Learning-Based Radiomics Analysis for Identifying KRAS Mutations in Non-Small-Cell Lung Cancer from CT Images: Challenges, Insights and Implications
Published 2025-01-01“…Larger multicentric datasets with balanced tumor stages, including multi-scanner datasets, seem to be necessary for building robust predictive models.…”
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7867
<i>Hylomecon japonica</i>: A Review About Botanical Aspects, Traditional Applications, Chemical Composition, and Pharmacological Properties
Published 2025-01-01“…Notably, alkaloids and saponins have shown significant anti-tumor and antibacterial effects. Additionally, extracts of <i>Hylomecon japonica</i> have demonstrated promising activity in anti-inflammatory, anti-obesity, and varicose vein treatment applications. …”
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7868
Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice
Published 2025-01-01“…Furthermore, PKP reduced the expression of F4/80 in liver and adipose tissue by 55.0% and 67.2%, respectively, and the serum levels of pro-inflammatory cytokines in including interleukin 1β by 22.9%, interleukin 6 by 44.6%, and tumor necrosis factor α by 7.8%, but increased the serum level of anti-inflammatory cytokine interleukin 10 by 27.1%. …”
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7869
Effects of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy on Breast Cosmetic Appearance and Systemic Stress of Patients with Breast Cancer
Published 2025-01-01“…After treatment, the levels of plasma procalcitonin (PCT) and tumor necrosis factor-α (TNF-α) in the two groups decreased. …”
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7870
A case of subcutaneous metastatic malignant melanoma of the left medial ankle: a case report and review of literature
Published 2024-12-01“…Several hypotheses have been proposed for how melanoma of unknown primary develops, two of which were considered in our patient case: (1) spontaneous regression of the primary tumor following metastasis or (2) the traumatic implantation of ectopic melanocytic cells in other tissues, such as the subcutaneous tissue. …”
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7871
Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization
Published 2025-02-01“…Atractylenolide I (ATR-I) is an active component of the Atractylodes macrocephala rhizome and possesses various pharmacological activities, including anti-tumor, anti-inflammatory, and anti-oxidant properties. …”
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7872
Interleukin-22 Plays a Protective Role by Regulating the JAK2-STAT3 Pathway to Improve Inflammation, Oxidative Stress, and Neuronal Apoptosis following Cerebral Ischemia-Reperfusio...
Published 2021-01-01“…IL-22 treatment remarkably reduced the expression of inflammatory cytokines, including IL-1β, monocyte chemotactic protein- (MCP-) 1, and tumor necrosis factor- (TNF-) α, both in serum and the ischemic cerebral cortex. …”
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7873
Silymarin: a promising modulator of apoptosis and survival signaling in cancer
Published 2025-01-01“…By upregulating pro-apoptotic and downregulating anti-apoptotic proteins, silymarin controls a series of events that result in tumor suppression and cell death in a variety of cancer types. …”
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7874
Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma
Published 2022-01-01“…Furthermore, this noninvasive assay could distinguish low-grade and high-grade tumors (P=0.0153). Conclusions. TERC is enriched in urinary exosomes from BLCA patients. …”
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7875
Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Published 2023-04-01“…Several of NMs can also be used for photothermal therapy to destroy cancer cells or enhance immune response to cancer by delivering immune‐stimulating molecules to immune cells or modulating the tumor microenvironment. NMs are being modified to overcome issues, such as toxicity, lack of selectivity, increase drug capacity, and bioavailability, for a wide spectrum of cancer therapies. …”
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7876
Integrating AI into Cancer Immunotherapy—A Narrative Review of Current Applications and Future Directions
Published 2025-01-01“…However, the complexity of immune responses and tumor heterogeneity challenges its effectiveness. …”
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7877
Anti-inflammatory effect of Plantago asiatica crude extract in rat gout arthritis model
Published 2025-12-01“…In comparison to in control rats, MSU induced joint space narrowing, ankle joint swelling, and increased levels of pro-inflammatory interleukin (IL)-1β, IL-17a, tumor necrosis factor (TNF)-α, and interferon (IFN)-γ, and reductions in anti-inflammatory IL-10 in the blood. …”
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7878
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis
Published 2022-01-01“…Moreover, OI effectively inhibited the expression of proinflammatory cytokines including interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), and IL-1β induced by Con A. …”
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7879
Proceso de Atención de Enfermería en un paciente con meningioma: Un estudio de caso clínico exploratorio
Published 2025-01-01“… Introducción. Los meningiomas son tumores extraaxiales que son originados a partir de las células de la aracnoides y son los tumores primarios más frecuentes del sistema nervioso central (SNC), adicionalmente existe un 70% mayor de probabilidad de que alguno de los hijos de una persona con tumor primario pueda presentarlo en algún momento de su vida, como es el caso de la persona reportada. …”
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7880
Targeting MAO-B with Small-Molecule Inhibitors: A Decade of Advances in Anticancer Research (2012–2024)
Published 2024-12-01“…Various monoamine oxidase B inhibitors have shown promise in inhibiting tumor growth and inducing apoptosis across different cancer types. …”
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