Recent updates of centromere proteins in hepatocellular carcinoma: a review by Zhongyuan Yang, Wenjiao Chen, Yunhui Liu, Yuxin Niu

“…Furthermore, chromosomal instability is a common characteristic of the majority of tumors. Chromosomal instability can lead to uncontrolled and sustained division and proliferation of malignant tumors. …”
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Self-Assembly Iron Oxide Nanoclusters for Photothermal-Mediated Synergistic Chemo/Chemodynamic Therapy by Xiang Li, Zhen Wang, Mian Ma, Zhouqing Chen, Xiang-long Tang, Zhong Wang

“…Experimental in vitro and in vivo evaluations showed that our photothermal-mediated chemo/CDT therapy could efficiently inhibit tumor growth and is therefore promising for cancer therapy.…”
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Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer by CHU Yudan, SUN Haidong, CUI Ran, ZHENG Hong

“…DRG-RS model was significantly correlated with tumor-related signaling pathways, clinical characteristics and drug sensitivity of gastric cancer patients. …”
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Current capabilities of endoscopic diagnosis of non-muscle invasive bladder cancer by I. N. Zaborskii, K. N. Safiullin, O. B. Karyakin, S. A. Ivanov, V. S. Chaikov, I. O. Dementev, A. V. Sidorin, G. N. Grishin, A. N. Yurchenko

“…In 75% of patients, this disease is diagnosed at an early stage (the tumor spreads to the muscle layer — non-muscle-invasive forms of RMP), which allows organ-preserving treatment. …”
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Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase by Lies De Groef, Manuel Salinas-Navarro, Griet Van Imschoot, Claude Libert, Roosmarijn E. Vandenbroucke, Lieve Moons

“…Hence, we propose a novel in vivo function for MMP-2, as an activating sheddase of tumor necrosis factor (TNF). Given the pivotal role of TNF as a proinflammatory cytokine and neurodegeneration-exacerbating mediator, these findings generate important novel insights into the pathological processes contributing to glaucomatous neurodegeneration and into the interplay of neuroinflammation and neurodegeneration in the CNS.…”
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Discussion on the mechanism of HER2 resistance in esophagogastric junction and gastric cancer in the era of immunotherapy by Yan Zhang, Wenxuan Fan, Fei Su, Xiaoling Zhang, Yunyi Du, Weiling Li, Yangjun Gao, Wenqing Hu, Jun Zhao

“…This review examines the mechanisms of drug resistance in HER2-positive G/GEJ cancer, the primary mechanisms of resistance explored include alterations in the HER2 receptor itself, such as mutations and changes in expression levels, as well as downstream signaling pathways, and interactions with the tumor microenvironment (TME). Furthermore, the review discusses the Novel therapeutic approaches, including the use of antibody-drug conjugates (ADCs) and combination therapies are assessed for their potential to enhance outcomes. …”
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Liver Microbiome in Healthy Rats: The Hidden Inhabitants of Hepatocytes by Xiao Wei Sun, Hua Zhang, Xiao Zhang, Peng Fei Xin, Xue Gao, Hong Rui Li, Cai Yun Zhou, Wen Min Gao, Xuan Xuan Kou, Jian Gang Zhang

“…The tumor and tissue microbiota of human beings have recently been investigated. …”
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Integrating single cell analysis and machine learning methods reveals stem cell-related gene S100A10 as an important target for prediction of liver cancer diagnosis and immunothera... by Shenjun Huang, Tingting Tu

“…Cancer stem cells are known to play a role in tumor development, metastasis, and resistance to treatment. …”
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Helicobacter pylori y cáncer gástrico by Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Belquis Palomino Besada, Miguel González-Carbajal Pascual, Danay Días Morejón

“…Desarrollo: El adenocarcinoma es el tumor gástrico más frecuente y el Helicobacter pylori es el agente etiológico principal. …”
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Plasma Levels of High-Mobility Group Box 1 during Peptide Vaccination in Patients with Recurrent Ovarian Cancer by Kayoko Waki, Kouichiro Kawano, Naotake Tsuda, Kimio Ushijima, Kyogo Itoh, Akira Yamada

“…High-mobility group box 1 (HMGB1) is a nuclear protein that is known to be secreted into extracellular fluids from injured cells, activated macrophages, and tumor cells. The clinical correlation of circulating HMGB1 levels with various diseases including cancer has been reported. …”
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The Role of IL-6 and TNF-Alpha Biomarkers in Predicting Disability Outcomes in Acute Ischemic Stroke Patients by Ciprian-Ionuț Băcilă, Maria-Gabriela Vlădoiu, Mădălina Văleanu, Doru-Florian-Cornel Moga, Pia-Manuela Pumnea

“…Introduction: Inflammatory biomarkers, including Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-alpha), play a significant role in influencing stroke outcomes, particularly in the progression of post-stroke disability. …”
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Analysis of periodontal status in Polish patients with rheumatoid arthritis treated with biological therapies by Joanna Samborska-Mazur, Dorota Sikorska, Marzena Liliana Wyganowska

“…Material and methods The cross-sectional study included 50 patients with RA treated with biologi­cal therapies: tumor necrosis factor inhibitors, interleukin-6 blockers. …”
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Anti-angiogenic effects of cationic zinc (II) phthalocyanine derivatives through photodynamic therapy by Seyma Isik, Mukaddes Ozcesmeci, Ayfer Kalkan Burat, Esin Hamuryudan, Ozge Can, Muge Serhatli

“…The ability of ZnPc1 to simultaneously target tumor cells and disrupt angiogenesis establishes it as a potent candidate for integrated cancer therapies that combine both antitumor and antiangiogenic strategies, offering a more effective approach to combat cancer progression.…”
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Seabuckthorn juice alleviates allergic symptoms in shrimp-induced food allergy mice by Hong Ren, Xiaofan Zhu, Shiyu Zhai, Xiaoping Feng, Zhuomin Yan, Jiao Sun, Ye Liu, Zhenpeng Gao, Fangyu Long

“…Seabuckthorn juice also reduced serum concentrations of tumor necrosis factor-α (TNF-α) as well as immunoglobulin E (IgE) and stimulated the secretion of interleukin-10 (IL-10) in mice with shrimp allergy. …”
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Scalable preparation of furanosteroidal viridin, β-viridin and viridiol from Trichoderma virens by Wen Zhang, Kazu Sunami, Shuo Liu, Desita Triana, Zetryana Puteri Tachrim, Rikuto Kikuchi, Tohru Taniguchi, Kenji Monde, Tsunayoshi Takehara, Da-Yang Zhou, Takeyuki Suzuki, Yasuyuki Hashidoko, Makoto Hashimoto, Yuta Murai

“…Abstract Viridin and viridiol, along with wortmannin, metabolized by filamentous fungus Trichoderma virens, are identical furanosteroids with high-potent inhibitory activity towards phosphatidylinositol 3-kinase (PI3K) that associates the growth of tumor cells. Therefore, structure–activity relationship study (SAR) of these furanosteroids contributes to the development of novel drugs. …”
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QUALITY OF LIFE COMPARATION IN METASTATIC BONE DISEASE PATIENT BEFORE AND AFTER SURGERY IN DR. SOETOMO GENERAL HOSPITAL by Ferdiansyah Mahyudin, Mouli Edward, Muhammad Hardian Basuki, Rizky Agung Satria

“…Background: Metastatic bone disease is bone pathologic process caused by spread of primary tumor. The incidence of metastatic bone disease varies between 20-75% corresponds to the primary site of the malignancy. …”
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Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells by Nidhi Varshney, Siddharth Singh, Meenakshi Kandpal, Vaishali Saini, Erle S. Roberston, Hem Chandra Jha

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Alternating magnetic field guiding system for MNP hyperthermia treatment of deep-seated cancers by Robert V. Stigliano, Ilona Danelyan, Giga Gabriadze, Levan Shoshiashvili, Ian Baker, P. Jack Hoopes, Roman Jobava, Fridon Shubitidze

“…This innovative approach offers a promising alternative to conventional field delivery methods by directing AMF through the body, concentrating it in the tumor region, reducing eddy currents in surrounding healthy tissue, and avoiding exposure of nearby metallic implants.…”
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Renal failure due to rectal neoplastic polyp: McKittrick–Wheelock syndrome—a case report by Ivan Valentinov Dimitrov, Theophil Angelov Sedloev, Ivan Petrov Vasilev, Slavyana Slavcheva Usheva, Yavor Asenov Nikolov, Nikolay Metodiev Penkov, Plamen Ivanov Penchev, Maria-Elena Boyadzhieva, Georgi Chavdarov Jelev

“…Abstract Background McKittrick–Wheelock syndrome is an uncommon and severe disorder caused by large hypersecretory tumors located in the distal colorectal area. Excessive secretion from adenomas is an unusual clinical manifestation that leads to severe electrolyte and fluid depletion, subsequently resulting in kidney injury. …”
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PD-L1 Expression and CD8+ T Cell Infiltration Predict a Favorable Prognosis in Advanced Gastric Cancer by Yangyang Wang, Chunchao Zhu, Wei Song, Jun Li, Gang Zhao, Hui Cao

“…Positive tumor PD-L1 expression was detected in 171 AGCs (33.60%) out of 509 AGCs. …”
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