Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis by Bin Wang, Xing-zhu Wen, Wei Zhang, Ming Qiu

“…Results In own series, Delphian lymph node metastasis was detected in 19 (9.9%) of 192 papillary thyroid carcinoma patients and was significantly associated with tumor size≥1 cm (P = 0.003), multifocality (P = 0.006) and extrathyroid extension (P < 0.001) in the multivariate analysis. …”
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Detachable Lip and Cheek Plumper for Rehabilitation of Facial Disfigurement by Nada Fathalla Abdelbagi, Ibrahim Ahmed Ismail, Fadia Awadalkreem, Mohammed Nasser Alhajj

“…A 19-year-old male attended the Prosthodontic Clinics at Faculty of Dentistry, the University of Khartoum, eight months after the surgical removal of a tumor. The chief complaint was difficulty eating or drinking. …”
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One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis by Yu Han, Fei Xiao, Qianli Ma, Zhenrong Zhang, Zaiyong Wang, Chaoyang Liang, Deruo Liu

“…One-stage procedure possess potential advantages in reducing hospital stay and cost, as well as preventing tumor progression.…”
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Prolapsed fallopian tube to the vagina after hysterectomy a year ago: A case report by Yu-Hsuan Lin, Huang-Ping Shen, Chih-Jen Tseng, Liang-Ying Wu, Li-Hsin Hsia

“…Case Report: A 45-year-old woman, with a history of hysterectomy for adenomyosis, presented with symptoms mimicking a vaginal tumor, including persistent discharge, abdominal pain, postcoital bleeding, and weight loss. …”
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Proton pump inhibitors enhance chemosensitivity, promote apoptosis, and suppress migration of breast cancer cells by Ihraiz Worood G., Ahram Mamoun, Bardaweel Sanaa K.

“…The acidic microenvironment surrounding tumor cells is a common feature inducing cancer cell invasiveness and chemoresistance. …”
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Development of Cutaneous Leishmaniasis after Leishmania Skin Test by Paulo R. Machado, Augusto M. Carvalho, Gustavo U. Machado, Marina L. Dantas, Sérgio Arruda

“…Mononuclear cells harvested from the patient were stimulated with Leishmania antigen and showed high levels of production of both tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ): 2,943 pg/mL and 2,313 pg/mL, respectively. …”
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SLC35A2 is a novel prognostic biomarker and promotes cell proliferation and metastasis via Wnt/β-catenin/EMT signaling pathway in breast cancer by Rushu Yan, Tianwen Chen

“…SLC35A2 was shown to be dysregulated in a number of tumor types according to multiple investigations. …”
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A CASE REPORT: EARLOBE RECONSTRUCTION ON CONGENITAL AURICULAR LOBE DEFECT USING Z-PLASTY by Nida' Fahima Amatullah, Iswinarno Doso Saputro

“…Earlobe defect  can be formed either from birth as congenital defect or secondary manifestation of other causes such as tumor and external factor such as earring usage or trauma. …”
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Hydration with Mannitol and Dextrose May Promote Cisplatin-Induced Nephrotoxicity: Test of Five Protocols of Hydration during Cisplatin Therapy in Rat Models by Mohammad-Sedigh Khosravi, Alireza Samimiat, Bahar Mazaheri, Farzaneh Ashrafi, Ardeshir Talebi, Mehdi Nematbakhsh

“…Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. …”
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The Expression Regulation and Cancer-Promoting Roles of RACGAP1 by Jiacheng Lin, Yuhao Zhu, Zhaoping Lin, Jindong Yu, Xiaobing Lin, Weiyuan Lai, Beibei Tong, Liyan Xu, Enmin Li, Lin Long

“…GAP has traditionally been known as a tumor suppressor. However, studies increasingly suggest that overexpressed RACGAP1 activates Rac and RhoA in multiple cancers to mediate downstream oncogene overexpression by assisting in the nuclear translocation of signaling molecules and to promote cytokinesis by regulating the cytoskeleton or serving as a component of the central spindle. …”
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Connexin 43 Communication Channels in Follicular Dendritic Cell Development and in Follicular Lymphomas by Hajnalka Rajnai, Ivett Teleki, Gergo Kiszner, Nora Meggyesházi, Peter Balla, Tamas Vancsik, Gyorgyi Muzes, Judit Csomor, Andras Matolcsy, Tibor Krenacs

“…Our results suggest that Cx43 channels are critical in FDC and “ex vivo” germinal center development and in the persistence of FDC in follicular lymphomas but do not affect tumor progression.…”
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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

“…Although increased immune checkpoint expression is generally linked to poor prognosis, tumors with high SOX2 expression exhibited higher responsiveness to immune checkpoint inhibitors, suggesting that targeting SOX2 may improve immune checkpoint therapy efficacy.The study highlights SOX2 as a key factor in cancer prognosis and immune infiltration across multiple tumor types. …”
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Intraoperative transcutaneous electrical acupoint stimulation combined with anesthesia to prevent postoperative cognitive dysfunction: A systematic review and meta-analysis. by Lin Gan, Kecheng Qian, Jinding Yang, Qian Cai, Qinyu Ye, Mengyuan Dai, Zhaoxing Jia, Tianxiang Jiang, Congcong Ma, Xianming Lin

“…Additionally, intraoperative TEAS demonstrated efficacy in reducing the contents of perioperative serum S100β protein (S100β), neuron-specific enolase (NSE), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in patients, and the improvement of these indexes may be the potential mechanism of TEAS in preventing POCD.…”
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Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma by Farshid Fathi, Behnam Sanei, Mazdak Ganjalikhani Hakemi, Reza F. Saidi, Abbas Rezaei

“…Several animal studies have shown the roles of cytokines in regulating liver regeneration following liver resection (LR), which is a type of surgery designed to remove cancerous tumors from the liver. This study investigated how the expressions and serum levels of some pro- and anti-inflammatory cytokines in patients with hepatocellular carcinoma (HCC) were changed during LR. …”
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Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy by Xiaoli Dai, Xiaoqiu Dai, Zheng Gong, Chen Yang, Keqin Zeng, Fang-Yuan Gong, Qiao Zhong, Xiao-Ming Gao

“…Here, we describe how RA-specific autoantibody deposits can train human monocytes to exert the hyperactive inflammatory response, particularly via the exacerbated release of tumor necrosis factor α (TNFα). Comparative transcriptomic analysis by plate-bound human IgG (cIgG) or β-glucan indicated that metabolic shift towards glycolysis is a crucial mechanism for trained immunity. …”
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Long-term results of surgical treatment of a locally advanced rectal cancer using extrafascial principle of dissection by P. V. Tsarkov, I. A. Tulina, D. N. Fedorov, A. Yu. Kravchenko, O. Yu. Samofalova

“…The true tumor progression to resected structures and organs was revealed in 22% of the cases. …”
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Integrated analysis of single-cell and bulk-RNA sequencing for the cellular senescence in prognosis of lung adenocarcinoma by Fengqiang Yu, Liangyu Zhang, Xun Zhang, Jianshen Zeng, Fancai Lai

“…Different TRGS patient groups showed varying degrees of immune cell infiltration, frequency of gene missense mutation, sensitivity to different drugs, and tumor mutation burden (TMB). Collectively, we developed a brand new signature composed of telomere-senescence related genes that can accurately predicts patients’ prognosis in LUAD, which provides new insights for future research into the role of cellular senescence in LUAD.…”
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PPARG Could Work as a Valid Therapeutic Strategy for the Treatment of Lung Squamous Cell Carcinoma by Shunbin Shi, Guiping Yu, Bin Huang, Yedong Mi, Yan Kang, Julia Pia Simon

“…Our results suggested that the activation of PPARG expression may inhibit the development and progression of LSCC through the regulation of LSCC upstream regulators and downstream marker genes, which were involved in tumor cell proliferation and protein polyubiquitination/ubiquitination.…”
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Elevated Circulating IL-1β and TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With an Adverse Outcome by Nicolaos Vitoratos, Constantinos Papadias, Emmanuel Economou, Evangelos Makrakis, Constantinos Panoulis, George Creatsas

“…Serum levels of Th1-type cytokines interleukin-1β (IL-1β), tumor necrosis factor alpha (TNF-alpha), and Th2-type cytokine interleukin 6 (IL-6) were measured, by ELISA, in 22 women with TACP and adverse outcome at admission (group A) and compared with the corresponding levels of 31 gestational age-matched women with TACP and successful outcome at admission (group B1) and discharge (group B2) and 22 gestational age-matched women with first-trimester uncomplicated pregnancy (group C) who served as controls. …”
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Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma by Licheng Li, Ting Chen, Jishi Wang, Mengxing Li, Qinshan Li

“…Immune infiltration of tumor cells resulted in the formation of a strong immunosuppressive microenvironment in high-risk patients. …”
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