HPV Infection in Esophageal Squamous Cell Carcinoma and Its Relationship to the Prognosis of Patients in Northern China by Fangli Cao, Hui Han, Fang Zhang, Baozhong Wang, Wei Ma, Yanwen Wang, Guiming Sun, Miao Shi, Yubo Ren, Yufeng Cheng

“…Twenty-five (86.2%) of the 29 HPV-positive tumors were stained positive for p16. HPV infected patients had better 5-year rates of OS (65.9% versus 43.4% among patients with HPV-negative tumors; P = 0.002 by the log-rank test) and had a 63% reduction in the risk of death (adjusted HR = 0.37, 95% CI = 0.16 to 0.82, and P = 0.01). …”
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Deviations in Circulating TNFα Levels and TNFα Production by Mononuclear Cells in Healthy Human Populations by T. Mózes, I. Baráth, K. Gornicsar, A. Grosz, Ta. Mózes, Cs. Göndöcs, P. Széphalmi, K. Gaál, E. Madarász

“…Objectives. Tumor necrosis factor alpha (TNFα) plays a pivotal role in the inflammatory host response. …”
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Undifferentiated Embryonal Sarcoma of the Liver Involving All Major Hepatic Veins Treated by Left Extended Trisectionectomy by Reinaldo Fernandes, Klaus Steinbrück, Jan-Peter Périssé, Rodrigo Luz, Renato Cano, Fernanda Cruz-Nunes, Diego Garcia, Rodrigo Diaz, Fernanda Cavalcanti Carneiro, Andrea Velloso, Carlos Frederico Campos, Marcelo Enne

“…CT scan and MRI revealed a heterogeneous and bulky expansive hepatic lesion, sparing only segment 6, with an estimated volume of 530 cm3, corresponding to a 1.2 FLR/BW ratio. The tumor involved the three major hepatic veins, but an inferior right hepatic vein was present, draining the spared segment 6. …”
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Induction of translation-suppressive G3BP1+ stress granules and interferon-signaling cGAS condensates by transfected plasmid DNA by Vladimir Majerciak, Zhi-Ming Zheng

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Changes in IL-16 Expression in the Ovary during Aging and Its Potential Consequences to Ovarian Pathology by Jessica Ramirez, Pincas Bitterman, Sanjib Basu, Animesh Barua

“…Ovarian tissues from premenopausal women (30-50 years old), women at early menopause (55-59 years old), and late menopause (60-85 years old) were used. In addition, tumor tissues from patients with ovarian high-grade serous carcinoma at early stage (n=5) were also used as reference tissue for comparing the expression of several selected markers in aging ovaries. …”
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Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice by Yanqing ZANG, Yingying CHUANG, Changyuan WANG, Yang CAO

“…The intake of WQP also reduced interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by 21% and 22%, respectively. …”
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Clinical Outcome of Eradication Therapy for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma according to H. pylori Infection Status by Ju Seok Kim, Sun Hyung Kang, Hee Seok Moon, Jae Kyu Sung, Hyun Yong Jeong

“…Fifty-four patients were enrolled: 12 H. pylori-negative and 42 H. pylori-positive patients. The tumor was located more frequently in both the proximal and distal parts of the stomach (P=0.001), and the percentage of multiple lesions was significantly greater in the H. pylori-negative group (P=0.046). …”
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Macrofocal multiple myeloma in the era of novel agents in China by Xuelin Dou, Ruixia Liu, Yang Liu, Nan Peng, Lei Wen, Daoxing Deng, Leqing Cao, Qian Li, Liru Wang, Fengrong Wang, Xiaodong Mo, Jin Lu

“…Prognostic staging and cytogenetic guidance for MFMM are often insufficient due to the low tumor burden in the bone marrow. Large cohort studies on this subgroup during the era of novel agents are limited. …”
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Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan by Ünal Metin Tokat, Ashkan Adibi, Ashkan Adibi, Esranur Aydın, Şevval Nur Bilgiç, Eylül Özgü, Onur Tutar, Mutlu Demiray

“…Here, we achieved a near-complete response in HR+ HER2-amplified and overexpressing metastatic BC twice through molecular tumor board (MTB) discussions: initially, with trastuzumab deruxtecan (T-DXd) when HER2 IHC was positive, and, then, with neratinib plus fulvestrant plus paclitaxel when IHC was negative. …”
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Neoadjuvant pembrolizumab-carboplatin-paclitaxel in locally advanced squamous cell carcinoma of the oral cavity: A case report and literature review by Abdulrahman Hesham, Fawaz AlOtaibi, D. David Kim, Yousef Alshamrani, Joao Hyppolito, Katie Jubala

“…This treatment resulted in a major pathological response, leading to a significant reduction in tumor size and allowing for surgical treatment. In addition, the patient remains free of locoregional disease nine months after the surgery. …”
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Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice by E. A. Litvinova, K. M. Achasova, M. A. Borisova, S. V. Zhenilo, E. B. Prokhortchouk, E. N. Kozhevnikova

“…However, in the experimental model of IBD, Kaiso protein did not play a signifcant role in the regulation of pro-inflammatory cytokines of tumor necrosis factor and interleukins 1 and 17.…”
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Effect of the size of nucleic acid delivery systems on their fate in cancer treatment by Mengyun Ye, Junni Gong, Wang Chen, Xiaoxuan Liu, Dandan Zhu

“…Nanoparticle (NP) size is an important parameter defining the blood circulation, distribution, tumor accumulation, and cellular uptake of NADS. …”
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Nuclear Position and Shape Deformation of Chromosome 8 Territories in Pancreatic Ductal Adenocarcinoma by Sylvia Timme, Eberhard Schmitt, Stefan Stein, Jutta Schwarz-Finsterle, Jenny Wagner, Axel Walch, Martin Werner, Michael Hausmann, Thorsten Wiech

“…Cell type specific radial positioning of chromosome territories (CTs) and their sub-domains in the interphase seem to have functional relevance in non-neoplastic human nuclei, while much less is known about nuclear architecture in carcinoma cells and its development during tumor progression. We analyzed the 3D-architecture of the chromosome 8 territory (CT8) in carcinoma and corresponding non-neoplastic ductal pancreatic epithelium. …”
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Prognostic Significance of DNA Cytometry in Carcinoma of the Uterine Cervix FIGO Stage IB and II by Hans Jürgen Grote, Nicolaus Friedrichs, Natalia Pomjanski, Helen Friderike Guhde, Olaf Reich, Alfred Böcking

“…Results: In multivariate statistical analysis DNA stemline ploidy using 2.2c as a cut‐off value and FIGO stage showed to be statistically significant available presurgery predictors of survival, whereas the postsurgical parameters lymphonodal status, tumor size and parametrial involvement were significantly correlated with survival. …”
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Research trends of neoadjuvant therapy for breast cancer: A bibliometric analysis by Laiping Xie, Yuhang Wang, Andi Wan, Lin Huang, Qing Wang, Wanyan Tang, Xiaowei Qi, Xiaofei Hu

“…This strategy is intended to reduce tumor size, thereby enabling less invasive surgical procedures and enhancing patient outcomes. …”
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Retrospective investigation of non-traumatic small intestine perforations: Our single center 7-year clinical experiences by Sebnem Cimen, Burak Ucaner, Ahmet Kamburoglu, Cilga Ecem Lamba

“…The most common causes of perforation were found as non-specific causes (35.6%), tumor (27.1%) and herniation (16.9%), respectively. …”
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Severe anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis with prolonged hyperammonemia: a case report by Chunxia Yan, Lingling Bai, Jingwei Du, Zonglei Chong, Guangjun Xu, Xiaoqian Yang

“…Conclusions Even if the short-term prognosis is good, regular tumor-related screening is essential for patients with severe anti-AMPAR-E to detect potential tumors early and improve long-term outcomes. …”
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Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway by Jianming Tang, Yu Cao, Hong Zhang, Rui Wang

“…Xenograft models were established to measure the extent of NSCLC tumor growth in vivo. Results Our study clarified the activation of the DcR3/protein kinase B (AKT)/glycogen synthase kinase 3β (GSK-3β) pathway in radioresistant NSCLC cells. …”
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Pleomorphic xanthoastrocytoma, case series and review of literature by Farrag Mohammad, Ahmed Abd Essattar Abd Elhakeem, Ahmad Algheriany, Ahmed Elshanawany

“…Abstract Background Pleomorphic xanthoastrocytoma is a rare circumscribed astrocytic glial neoplasm that represents less than 1% of astrocytic tumors. This is a retrospective descriptive hospital-based study of this rare tumor that includes five patients. …”
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C/EBPβ Regulates HIF-1α-Driven Invasion of Non-Small-Cell Lung Cancer Cells by Seung Hee Seo, Ji Hae Lee, Eun Kyung Choi, Seung Bae Rho, Kyungsil Yoon

“…Hypoxia, a feature of solid tumors, plays a role in cancer progression by inducing resistance to therapy and accelerating metastasis. …”
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