Effect of Ashi Point Pricking and Cupping Combined with Quadriceps Femoris Function Exercise on the Clinical Curative Effect of Knee Osteoarthritis by Zhiqiang HUANG, Yu LIU, Zhaoyuan SU, Jiafu SU, Qiang WU

“…The changes of the Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)score, range of motion of joints, levels of inflammatory factors and clinical efficacy were compared between the two groups before and after treatment.Results:The clinical effect of the comprehensive group was better than the drug group(<italic>P</italic>&lt;0.05).WOMAC score(pain, daily activities, joint stiffness, comprehensive score)of the two groups after treatment was significantly lower than that before treatment(<italic>P</italic>&lt;0.05).After treatment, WOMAC score of the comprehensive group was significantly lower than that of the drug group(<italic>P</italic>&lt;0.05);joint range of motion of the two groups was larger than that before treatment(<italic>P</italic>&lt;0.05), and joint range of motion of the comprehensive group was larger than that of the drug group(<italic>P</italic>&lt;0.05);tumor necrosis factor alpha(TNF-α)and interleukin 1(IL-1)levels of the two groups were lower than those before treatment(<italic>P</italic>&lt;0.05), TNF-α and IL-1 of the comprehensive group were significantly lower than those of the drug group(<italic>P</italic>&lt;0.05).Conclusion:The method of Ashi point pricking and cupping combined with quadriceps femoris functional exercise can relieve joint pain, increase joint range of motion, reduce the inflammatory index of joint, and then improve the function of knee joint of KOA.…”
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Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography by Doh Young Lee, Tack-Kyun Kwon, Myung-Whun Sung, Kwang Hyun Kim, J. Hun Hah

“…The frequency of ETE was greater in the patients with greater degrees of tumor contact and disruption of capsule, as revealed by both US and CT scans (positive predictive value of 72.2% and 81.8%, resp.). …”
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Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation by M. Hidayat Budi Kusumo, Adi Prayitno, Soetrisno ., Abdurahman Laqif

“…Croton oil-induced hemorrhoid mouse models were established to assess tissue edema, inflammation, tumor necrosis factor (TNF-α) expression, transforming growth factor-β (TGF-β) expression, collagen ratio, and MMP-9 activity. …”
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Identification and validation of a metabolic-related gene risk model predicting the prognosis of lung, colon, and breast cancers by Jiyauddin Khan, Chanchal Bareja, Kountay Dwivedi, Ankit Mathur, Naveen Kumar, Daman Saluja

“…Abstract Metabolic reprogramming, vital for cancer cells to adapt to the altered microenvironment, remains a topic requiring further investigation for different tumor types. Our study aims to elucidate shared metabolic reprogramming across breast (BRC), colorectal (CRC), and lung (LUC) cancers. …”
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Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy by Jianbo He, Hong Wang, Ying Liu, Wen Li, Dorothy Kim, Hu Huang

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Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…Modern pharmacological studies have demonstrated that AR and ARS possess immune-enhancing, anti-tumor, anti-inflammatory, and anti-angiogenic properties. …”
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Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…Compared to WPC and WPI, WPH improved peak torque associated with strength training without reducing the creatine kinase (CK) and tumor necrosis factor alpha (TNF-α) levels in this type of physical activity, and the decreases in CK and lactate dehydrogenase (LDH) associated with aerobic exercise were significant. …”
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Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes by Shiqin Peng, Ping Wei, Qun Lu, Rui Liu, Yue Ding, Jiuliang Zhang

“…For inflammatory factors, feeding of 50% fraction could also reduce the levels of interleukin 6 (IL-6), tumor necrosis factor α (TNF-α), monocyte chemotactic protein 1 (MCP-1), and cyclooxygenase-2 (COX-2) in liver homogenate. …”
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Pancreatic Tail Schwannoma in a 44-Year-Old Male: A Case Report and Literature Review by Ahmed Abu-Zaid, Ayman Azzam, Hussam Abou Al-Shaar, Abdullah M. Alshammari, Tarek Amin, Shamayel Mohammed

“…At a postoperative 6-month followup, patient was completely asymptomatic and CT scan imaging showed no evidence of tumor recurrence. Moreover, a literature review on pancreatic schwannomas is presented.…”
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ZNF169 promotes thyroid cancer progression via upregulating FBXW10 by Wen Luo, Qiyu Xiao, Ying Fu

“…Recovery assays in vitro and in vivo demonstrated that FBXW10 knockdown reversed the effects of ZNF169 overexpression on THCA cell proliferation and tumor growth. Conclusions In summary, ZNF169 promotes THCA progression via upregulation of FBXW10, which may provide a novel theoretical basis for the development of clinical therapies for THCA.…”
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Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Viru... by Noboru Uchide, Kunio Ohyama, Toshio Bessho, Makoto Takeichi, Hiroo Toyoda

“…Proinflammatory cytokines, such as interleukin (IL)-6, tumor necrosis factor (TNF)-α, and interferon (IFN)-β, were identified as a member of the MDI factor. …”
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Analisis Jumlah Leukosit pada Penderita Kanker Payudara yang Menjalani Kemoterapi Di RS Bhayangkara Kota Kediri by Mely Purnadianti, Arshy Prodyanatasari, Yoanita Indra Kumala Dewi, Ningsih Dewi Sumaningrum, Yulvia Arifatunnisa

“… Kanker payudara yaitu kondisi adanya tumor ganas yang menyerang jaringan payudara seperti kelenjar susu (kelenjar pembuat air susu), saluran kelenjar (saluran air susu), dan jaringan penunjang payudara. …”
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Prognostic Value of Melanoma Inhibitory Activity Protein in Localized Cutaneous Malignant Melanoma by Angela Sandru, Eugenia Panaitescu, Silviu Voinea, Madalina Bolovan, Adina Stanciu, Sabin Cinca, Alexandru Blidaru

“…In order to appreciate a patient’s individual prognosis, an attempt is made to find new tumor markers that parallel the disease progression. …”
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Dramatic response of advanced pulmonary sarcomatoid carcinoma to tislelizumab combined with anlotinib: a case report by Ranran Li, Xiliang Di, Yuan Li, Hao Li, Chonghua Liu

“…The patient initially received nine cycles of treatment with tislelizumab and anlotinib, resulting in a significant shrinkage of the lung tumor. Subsequently, anlotinib was discontinued due to bleeding in the brain metastasis, and the patient received two additional cycles of tislelizumab. …”
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Mechanisms of inflammatory microenvironment formation in cardiometabolic diseases: molecular and cellular perspectives by Menghua Liu, Rumeng Chen, Zhiwei Zheng, Shuling Xu, Chunyan Hou, Yining Ding, Mengling Zhang, Meihua Bao, Binsheng He, Sen Li

“…In atherosclerosis, oxidized low-density lipoprotein (ox-LDL) and pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α) activate immune cells contributing to foam cell formation and arterial wall thickening. …”
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Structural, Optical, Antibacterial, and Anticancer Properties of Cerium Oxide Nanoparticles Prepared by Green Synthesis Using Morinda citrifolia Leaves Extract by Abozer Y. Elderdery, Badr Alzahrani, Abdulrahim A. Alabdulsalam, Siddiqa M. A. Hamza, Ahmed M. E. Elkhalifa, Abdulaziz H. Alhamidi, Fehaid Alanazi, A. Mohamedain, Suresh Kumar Subbiah, Pooi Ling Mok

“…The anticancer properties of the green synthesized CeO2 NPs against human acute lymphoblastic leukemia (ALL) MOLT-4 cells were further explored by the meticulous study of their ability to diminish cancer cell viability (cytotoxicity), accelerate apoptosis, escalate intracellular reactive oxygen species (ROS) accumulation, decline the mitochondria membrane potential (MMP) level, modify the cell adhesion, and shoot up the activation of proapoptotic markers, caspase−3, −8, and −9, in the tumor cells. Altogether, the outcomes demonstrated that our green synthesized CeO2 NPs are an excellent candidate for alternative cancer therapy.…”
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Recurrent Painful Ophthalmoplegic Neuropathy and Oculomotor Nerve Schwannoma: A Pediatric Case Report with Long-Term MRI Follow-Up and Literature Review by Maria Giuseppina Petruzzelli, Mariella Margari, Flora Furente, Maria Carmela Costanza, Anna Rosi Legrottaglie, Franca Dicuonzo, Lucia Margari

“…Actually, oculomotor nerve tumors may be masquerade as RPON so that MRI follow-ups are required to detect the possibility of tumor etiology. …”
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The mitigating effect of a topical preparation of amlodipine on imiquimod-induced psoriasis-like lesion in mice Authors by Zainab A. Mahdi, Fouad K. Gatea, Omeed M. Hassan, Zeena A. Hussein

“…The levels of interleukin-17 (IL-17), tumor necrosis factor-alpha (TNF-a), and vascular endothelial growth factor (VEGF) were significantly ameliorated by topical amlodipine Ointment in comparison with the untreated imiquimod-induced psoriatic mice group. …”
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Genetics of Endometrial Cancers by Tsuyoshi Okuda, Akihiko Sekizawa, Yuditiya Purwosunu, Masaaki Nagatsuka, Miki Morioka, Masaki Hayashi, Takashi Okai

“…The most frequently altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors is PTEN. Microsatellite instability is another important genetic event in this type of tumor. …”
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Rotavirus VP6 Adjuvant Effect on Norovirus GII.4 Virus-Like Particle Uptake and Presentation by Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo by Kirsi Tamminen, Suvi Heinimäki, Timo Vesikari, Vesna Blazevic

“…Furthermore, VP6 copulsing increased GII.4 VLP uptake by 37% and activated BMDCs to secrete 2-5-fold increased levels of interleukin 6 and tumor necrosis factor α compared to VLP pulsing alone. …”
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