Suggested Topics within your search.
Suggested Topics within your search.
- Cancer 1
- Immune System 1
- Immunity 1
- Orthopedic surgery 1
- Orthopedics 1
- Pediatrics 1
- Tumors 1
-
7521
Bilateral Testicular Infarction from IgA Vasculitis of the Spermatic Cords
Published 2017-01-01“…Microscopically, both testicles revealed large abscess formation destroying almost the entire testicular parenchyma without tumor cells. Spermatic cord margins were further scrutinized microscopically to show bilateral vasculitis in many small size vessels, confirmed by positive endothelial staining for IgA. …”
Get full text
Article -
7522
The Multifaceted Roles of MicroRNA-181 in Stem Cell Differentiation and Cancer Stem Cell Plasticity
Published 2025-01-01“…Cancer stem cells are a critical tumor cell population that drives tumorigenesis, cancer progression, drug resistance, and metastasis. …”
Get full text
Article -
7523
Giant Cell Fibroma in a Two-Year-Old Child
Published 2016-01-01“…The giant cell fibroma is a benign nonneoplastic fibrous tumor of the oral mucosa. It occurs in the first three decades of life in the mandibular gingiva, predominantly, showing predilection for females. …”
Get full text
Article -
7524
Protective effects of myrtenol against paraquat-induced toxicity in rats
Published 2025-01-01“…Results PQ decreases the levels or activities of superoxide dismutase (SOD), catalase (CAT), and Thiol, while increasing the levels or activities of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and malondialdehyde (MDA). …”
Get full text
Article -
7525
Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia
Published 2009-01-01“…They were evaluated clinically for the occurrence of complications and by the laboratory parameters (blood levels of glutathione peroxidase (Glu.PX) antioxidant enzyme, malondialdehyde (MDA), tumor necrosis factor-𝛼 (TNF-𝛼), liver enzymes, and bone marrow picture). …”
Get full text
Article -
7526
RNA N4‐acetylcytidine modification and its role in health and diseases
Published 2025-01-01“…Furthermore, this review delves into the central roles and molecular mechanisms of ac4C modification in regulating malignant proliferation, cell cycle arrest, EMT, drug resistance, cell death, cancer metabolism, and tumor immunotherapy. It also emphasizes the potential of NAT10 as a prognostic biomarker and its therapeutic potential as a target for disease treatment. …”
Get full text
Article -
7527
Resveratrol-driven macrophage polarization: unveiling mechanisms and therapeutic potential
Published 2025-01-01“…For example, resveratrol can activate the senescence-associated secretory phenotype (SASP) pathway and inhibit the signal transducer and activator of transcription (STAT3) and sphingosine-1-phosphate (S1P)-YAP signaling axes, promoting M1 polarization or suppressing M2 polarization, thereby inhibiting tumor growth. Conversely, it can promote M2 polarization or suppress M1 polarization by inhibiting the NF-κB signaling pathway or activating the PI3K/Akt and AMP-activated protein kinase (AMPK) pathways, thus alleviating inflammatory responses. …”
Get full text
Article -
7528
Cáncer de mama masculino: estudio de 36 años. Comportamiento en la provincia de Cienfuegos
Published 2016-12-01“…Las variables estudiadas fueron: edad, mama afectada, localización anatómica, tipo histológico, modalidad de biopsia empleada, etapa clínica del tumor en el caso de los carcinomas, técnica quirúrgica aplicada y evolución de los pacientes. …”
Get full text
Article -
7529
Impact of the Siewert Classification on the Outcome of Patients Treated by Preoperative Chemoradiotherapy for a Nonmetastatic Adenocarcinoma of the Oesophagogastric Junction
Published 2015-01-01“…For OGJA treated with preoperative CRT and surgery, ORR and CRMR were lower for patients with Siewert I tumors in comparison with Siewert II/III tumors.…”
Get full text
Article -
7530
Human Calmodulin-Like Protein CALML3: A Novel Marker for Normal Oral Squamous Mucosa That Is Downregulated in Malignant Transformation
Published 2013-01-01“…The purpose of this study was to determine if the epithelial-specific human calmodulin-like protein (CALML3) could be used as marker for the various phases of oral tumor progression. Immunohistochemical analysis using an affinity-purified CALML3 antibody was performed on biopsy-confirmed oral tissue samples representing these phases. …”
Get full text
Article -
7531
Pulmonary enteric adenocarcinoma with progression disease after second - line therapy: a case report
Published 2025-01-01“…Pulmonary enteric adenocarcinoma (PEAC, also known as Enteric-type adenocarcinoma of the lung, lung - ETAC) is a rare subtype of non-small cell lung cancer (NSCLC) that has the same morphological and immunohistochemical characteristics as colorectal adenocarcinoma and requires gastroenteroscopy to rule out lesions of enteric origin. As a rare solid tumor in lung cancer, PEAC has unique clinical outcome, imaging, pathological and molecular characteristics, and poor prognosis. …”
Get full text
Article -
7532
Inhibition of BRD4 attenuated IFNγ-induced apoptosis in colorectal cancer organoids
Published 2025-01-01“…Methods We knocked out Brd4 in tumor organoids carrying mutations in Apc and Kras to generate Brd4KO organoids, and performed RNA-seq. …”
Get full text
Article -
7533
Neuroblastoma-derived hypoxic extracellular vesicles promote metastatic dissemination in a zebrafish model.
Published 2024-01-01“…Here we investigate the effects of EVs derived from neuroblastoma (NB), a pediatric solid tumor, on metastatic niche formation using the zebrafish as an in vivo model. …”
Get full text
Article -
7534
Hospital Surgical Volume, Utilization, Costs and Outcomes of Retroperitoneal Lymph Node Dissection for Testis Cancer
Published 2012-01-01“…Limitations include inability to adjust for tumor characteristics and absence of outpatient outcomes. …”
Get full text
Article -
7535
Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview
Published 2013-01-01“…The significant decrease in MPRL levels and tumor volume in response to dopamine agonist therapy is suggestive for the tumoral origin of this isoform. …”
Get full text
Article -
7536
Severe IgG4-Related Disease in a Young Child: A Diagnosis Challenge
Published 2015-01-01“…Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognized syndrome that can appear with multiple organ involvement, typically with tumor-like swelling, lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, and elevated serum IgG4 concentrations. …”
Get full text
Article -
7537
Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection
Published 2014-01-01“…HCV thyroid infection could act by upregulating CXCL10 gene expression and secretion in thyrocytes recruiting Th1 lymphocytes that secrete interferon-γ and tumor necrosis factor-α. These cytokines might induce a further CXCL10 secretion by thyrocytes, thus perpetuating the immune cascade, which may lead to the appearance of autoimmune thyroid disorders in genetically predisposed subjects. …”
Get full text
Article -
7538
Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway
Published 2015-01-01“…Hydroethanolic extract of M. oleifera flower significantly suppressed the secretion and expression of NO, prostaglandin E2 (PGE2), interleukin- (IL-) 6, IL-1β, tumor necrosis factor-alpha (TNF-α), nuclear factor-kappa B (NF-κB), inducible NO synthase (iNOS), and cyclooxygenase-2 (COX-2). …”
Get full text
Article -
7539
Phenolic Composition, Antioxidant Activity, and In Vitro Availability of Four Different Berries
Published 2016-01-01“…Polyphenols from berries have proved healthy effects after “in vitro” and “in vivo” studies, such as preventing tumor growing and neurodegenerative and cardiovascular diseases. …”
Get full text
Article -
7540
The Benefits and Risks of Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma: Prospective Cohort Study
Published 2015-01-01“…The two groups of patients were similar in age, sex ratio, follow-up duration, and tumor size (P=0.227, 0.359, 0.214, and 0.878, resp.). …”
Get full text
Article