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7481
Comprehensive analysis of ceRNA Networks in UCEC: Prognostic and therapeutic implications.
Published 2025-01-01“…Furthermore, immune infiltration studies highlighted significant correlations between CDKN2B-AS1, IGF2BP3, and multiple immune cell types, suggesting that this axis regulates the tumor immune microenvironment. These findings suggest that the CDKN2B-AS1-hsa-miR-497-5p-IGF2BP3 axis is a key regulatory element in UCEC and a potential therapeutic target.…”
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7482
Multi-Walled Carbon Nanotubes Accelerate Leukaemia Development in a Mouse Model
Published 2024-09-01“…Inflammation is associated with an increased risk of developing various cancers in both animals and humans, primarily solid tumors but also myeloproliferative neoplasms (MPNs), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML). …”
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7483
Comparative analysis of salivary cytokine profiles in newly diagnosed pediatric patients with cancer and healthy children
Published 2025-01-01“…At diagnosis, patients with leukemia and solid tumors showed elevated levels of interferon-γ, interleukin (IL)-1α, IL-1β, IL-4, IL-5, IL-8, IL-10, and tumor necrosis factor. …”
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7484
Impact on CD4+ CD25High-CD127low regulatory T (Treg) cells of neoadjuvant therapy for rectal cancer patients
Published 2023-07-01“…Objective: To evaluate proportional changes in peripheral blood immune cells in rectal cancer patients after neoadjuvant therapy and assess the relationship between tumor regression and regulatory T (Treg) cells. Materials and Methods: Rectal cancer patients who had received neoadjuvant therapy prior to surgery at Shanxi Cancer Hospital between January and September 2018 were enrolled in the study. …”
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7485
Deep learning-based prediction of HER2 status and trastuzumab treatment efficacy of gastric adenocarcinoma based on morphological features
Published 2025-01-01“…In clinical practice, HER2 positivity is identified through immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH), whereas deep learning (DL) can predict HER2 status based on tumor histopathological features. However, it remains uncertain whether these deep learning-derived features can predict the efficacy of anti-HER2 therapy. …”
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7486
Comparative Analysis of Edge Detection Operators Using a Threshold Estimation Approach on Medical Noisy Images with Different Complexities
Published 2024-12-01“…This study focuses on medical images from three distinct datasets: retinal images, brain tumor segmentation, and lung segmentation from CT scans. …”
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7487
Pulmonary cavernous hemangioma: a case report
Published 2025-01-01“…In summary, the thoracic surgeon could not rule out the possibility of lung malignant tumors and chose to proceed with surgical excision to secure a conclusive diagnosis. …”
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7488
The ERK1/2 Inhibitor U0126 Attenuates Diabetes-Induced Upregulation of MMP-9 and Biomarkers of Inflammation in the Retina
Published 2013-01-01“…The expression of inducible nitric oxide synthase (iNOS), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) was examined by Western blot analysis. …”
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7489
Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial
Published 2025-01-01“…This double-blind, placebo-controlled, randomized clinical trial aimed to evaluate the effects of a tocotrienol-rich fraction (TRF) supplementation (300 mg/day) on oxidative stress and inflammatory markers, including transcription factors in nondialysis (ND) and hemodialysis (HD) CKD patients for three months. Interleukin-6, tumor necrosis factor-α (IL-6 and TNF-α), C-reactive protein (CRP), lipid peroxidation, biochemical parameters, and transcription factors such as NRF2 and NF-κB mRNA expression were evaluated. …”
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7490
Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study
Published 2016-01-01“…We observed an increase in the transcription factor, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NF-κB1), in parallel with ICAM-1, in human retinal endothelial cells treated with tumor necrosis factor-alpha (TNF-α), and identified putative binding sites for NF-κB1 within the ICAM-1 regulatory region. …”
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7491
Early detection of canine hemangiosarcoma via cfDNA fragmentation and copy number alterations in liquid biopsies using machine learning
Published 2025-01-01“…Hemangiosarcoma is a highly malignant tumor commonly affecting canines, originating from endothelial cells that line blood vessels, underscoring the importance of early detection. …”
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7492
Psychological Stress Delays Periodontitis Healing in Rats: The Involvement of Basic Fibroblast Growth Factor
Published 2012-01-01“…The periodontitis healing condition was assessed, and the expression of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and bFGF were tested by immunohistochemistry. …”
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7493
A review of biodegradable biliary stents made of magnesium metals: Current progress and future trends
Published 2025-01-01“…Biliary system, which is responsible for transporting bile from the liver into the intestine, is commonly damaged by inflammation or tumors eventually causing liver failure or death. …”
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7494
Immunological characterization and prognostic of colon cancer evaluated by angiogenesis-related features: a computational analysis and in vitro experiments
Published 2025-01-01“…We evaluated the differences in tumor immune microenvironment based on prognostic signature. …”
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7495
Malignant Glioma in the Cerebellum Presenting as Multiple Small Lesions
Published 2019-01-01“…Malignant glioma, the most common malignant primary brain tumor in adults, usually occurs in supratentorial space as a single mass lesion, and cerebellar location and multiple appearance are uncommon. …”
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7496
circ_0001588 Induces the Malignant Progression of Hepatocellular Carcinoma by Modulating miR-874/CDK4 Signaling
Published 2021-01-01“…In vivo studies using a nude mouse model showed that circ_0001588 downregulation reduced tumor size. Moreover, miR-874 was predicted as a target of circ_0001588. …”
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7497
Differentiation of Lynch syndrome from other forms of non-polyposis colorectal cancer among Russian patients
Published 2014-08-01“…Search of microsatellite instability (MSI), characteristic for Lynch's syndrome, was carried out in tumor samples of 73 patients by fragment analysis method. …”
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7498
MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β-catenin signaling pathway
Published 2025-01-01“…Conclusions Mucin 5B, oligomeric mucus/gel-forming regulates the immune escape of nasopharyngeal carcinoma cells and participates in tumor progression by mediating the Wnt/β-catenin signaling pathway.…”
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7499
Inflammatory Profile of Awake Function-Controlled Craniotomy and Craniotomy under General Anesthesia
Published 2009-01-01“…It is also likely that function-controlled craniotomy does not cause a greater emotional challenge than tumor resection under general anesthesia.…”
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7500
Tufted Angioma in Children: Report of Two Cases and a Review of the Literature
Published 2014-01-01“…Tufted angioma (TA) is a benign vascular tumor with endothelial origin. It is extremely rare in oral mucosa; only seven cases have been reported in the literature so far. …”
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