The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Cristian Scheau, Ioana Anca Badarau, Raluca Costache, Constantin Caruntu, Gratiela Livia Mihai, Andreea Cristiana Didilescu, Carolina Constantin, Monica Neagu

“…The epithelial-mesenchymal transition (EMT) is a transformation process mandatory for the local and distant progression of many malignant tumors, including hepatocellular carcinoma (HCC). …”
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Neutrophils: From Inflammatory Bowel Disease to Colitis-Associated Colorectal Cancer by Chen T, Liu J, Hang R, Chen Q, Wang D

“…This colorectal malignant tumor that arises from chronic IBD is referred to as colitis-associated colorectal cancer (CAC). …”
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A rare case of recurrent adenoid cystic carcinoma of the breast with weak hormone receptor positivity by Jonathan W. Ray, MD, Mena Louis, DO, Nathaniel Grabill, MD, Jaime Morel Ruiz, MD, Priscilla Strom, MD

“…The rarity of ACC complicates establishing standard protocols, necessitating personalized treatment plans based on tumor and patient factors. Recurrent breast ACC presents management challenges due to rarity and unpredictable behavior. …”
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CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression by Agapitos Patakas, Bochong Li, Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Hannah M Findlay, Timothy B London

“…Background Despite significant progress in the development of T cell-engaging therapies for various B-cell malignancies, a high medical need remains for the refractory disease setting, often characterized by suboptimal target levels.Methods To address this issue, we have developed a 65-kDa multispecific antibody construct, CLN-978, with affinities tuned to optimize the killing of low-CD19 expressing tumor cells. CLN-978 bound to CD19 on B cells with picomolar affinity, and to CD3ε on T cells with nanomolar affinity. …”
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Categorizing and Determining of BI-RAD Breast Cancer Score by Using Deep Learning Techniques by Azhar Kassem Flayeh, Ali Douik

“…Diagnosticians determine breast cancer stage by examining tumor size, shape, and spread. Artificial intelligence users employ these factors as fixed values to classify the illness using region of interest (RIO), Gray Level Co-Occurrence Matrix (GLCAM), clustering, or mass constraints like diameter and volume. …”
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Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies by Gui-Chen Ye, Hao Peng, Jia-Cheng Xiang, Ling-Tao Miao, Cheng-Zhi Liu, Shao-Gang Wang, Qi-Dong Xia

“…Results In the study, we found the consistency of the special intratumor microbiome of both non-metastatic tumors and metastatic tumors. And we dig the gut microbiome in patients with different treatments. …”
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The role of stereotactic radiotherapy in the treatment of the local recurrence of colorectal cancer: A case report by Radosavljević Kristina, Ivanov Olivera, Bojović Marko, Ličina Jelena, Protić Mlađan, Prvulović-Bunović Nataša

“…Magnetic resonance imaging (MRI) examination diagnosed a tumor lesion of the rectosigmoid junction with a perilesional abscess collection and several fistulous channels communicating with the perianal skin. …”
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The pharmacology, toxicology, and detoxification of Aconitum kusnezoffii Reichb., traditional and modern views by Kenneth Happy, Sungyu Yang, Chang Ho Kang, Youngmin Kang

“…These compounds exhibit various pharmacological activities including anti-inflammatory, analgesics, anti-cancer, anti-tumor, anti-arhythmic and pain-relieving properties. …”
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Impact of stain variation and color normalization for prognostic predictions in pathology by Siyu Lin, Haowen Zhou, Mark Watson, Ramaswamy Govindan, Richard J. Cote, Changhuei Yang

“…This study used sample data from a previously reported DNN that was able to identify patients with early-stage non-small cell lung cancer (NSCLC) whose tumors did and did not metastasize, with high accuracy, based on training and then testing of digital images from H&E stained primary tumor tissue sections processed at the same time. …”
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Clinical benefits of central pancreatectomy for a patient with pancreatic schwannoma and diabetes by Long Cheng Zhao, Zi Ye Li, Fan Wu, Yue Hu, Bai Lin Wang

“…Abstract Schwannomas are tumors that originate from the glial cells of the nervous system and can occur on myelinated nerve fibers throughout the body, especially in the craniofacial region. …”
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A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action by Shira Cohen, Faina Barer, Sara Bar-Yehuda, Adriaan P. IJzerman, Kenneth A. Jacobson, Pnina Fishman

“…The advantage of allosteric modulators is their capability to target specifically areas where adenosine levels are increased such as inflammatory and tumor sites, whereas normal body cells and tissues are refractory to the allosteric modulators due to low adenosine levels. …”
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Effects of proprioceptive training in the recovery of patients submitted to meniscus surgery: systematic review and meta-analysis by Song Jin, Xiaoxiao Liu, Di Zhang, Ju Wang, Tianyu Zhao, Jiang Ma, Huaimin Lu

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Profil Klinikopatologi Karsinoma Sel Skuamosa Kepala dan Leher di Padang by Zulda Musyarifah, Yenita Yenita

“…Tujuan: Mengetahui profil klinikopatologi KSS kepala dan leher berdasarkan kelompok usia, jenis kelamin, lokasi tumor, stadium, derajat diferensiasi dan Invasi Perineural (IPN). …”
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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence. by Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

“…The formation of a trimeric complex between the HPV E6 oncoprotein, the cellular ubiquitin ligase E6AP and the p53 tumor suppressor protein leads to proteolytic p53 degradation and plays a central role for HPV-induced cell transformation. …”
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Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features by Yao Liu, Bohan Yang, Qi Qi, Shijie Liu, Yiheng Du, Linlin Ye, Qiong Zhou

“…GSVA revealed significant correlations between these genera and tumor metabolic pathways as well as various signaling pathways including PI3K, Hippo, and p53.ConclusionmNGS showed a higher pathogen detection rate than culture-based CMTs in lung cancer patients with LRTIs, and also characterizing LRT microbiome composition and revealing potential microbial functions linked to lung carcinogenesis.…”
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Delivering Volumetric Hyperthermia to Head and Neck Cancer Patient-Specific Models Using an Ultrasound Spherical Random Phased Array Transducer by Muhammad Zubair, Imad Uddin, Robert Dickinson, Chris J. Diederich

“…This approach shows potential for treating a range of tumors, notably deep-seated and challenging oropharyngeal cancers.…”
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Familial Lymphoproliferative Malignancies and Tandem Duplication of NF1 Gene by Gustavo Fernandes, Mirela Souto, Frederico Costa, Edite Oliveira, Bernardo Garicochea

“…Neurofibromatosis type 1 is a genetic disorder caused by loss-of-function mutations in a tumor suppressor gene (NF1) which codifies the protein neurofibromin. …”
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Trim13‐induced ubiquitination of RPS27A inhibits the progression of lung cancer by depending on the inactivation of NF‐κB signaling pathway by Lailing Li, Hui Zhou, Yayun Cui, Ke Xu

“…The study demonstrated TRIM13 was identified as a novel tumor suppressor gene of LC and its overexpression suppressed LC progression in vitro and in vivo. …”
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Preparation, Synthesis and Characterization of La(1-x)Sr(x)MnO3 Alloy by Ramlan Ramlan, Fatma Husaini, Jan Setiawan, Ferry Budhi Susetyo, Hamdan Akbar Notonegoro, Silviana Simbolon, Dwi Nanto, Yunasfi Yunasfi

“… Magnetic particles have been used for hyperthermia by inserting ferromagnetic material into tumor tissue. La(1-x)Sr(x)MnO3 is one of the best candidates for hyperthermia due to higher magnetic at ambient temperature and their Curie temperature easily adjusted. …”
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Survival after Abdominoperineal and Sphincter-Preserving Resection in Nonmetastatic Rectal Cancer: A Population-Based Time-Trend and Propensity Score-Matched SEER Analysis by Rene Warschkow, Sabrina M. Ebinger, Walter Brunner, Bruno M. Schmied, Lukas Marti

“…It is unclear whether this adverse outcome is due to the surgical procedure itself or is a consequence of tumor-related characteristics. Study Design. Patients were identified from the Surveillance, Epidemiology, and End Results database. …”
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