Optimized for routine: highly sensitive fluorescent Telomeric Repeat Amplification Protocol (f-TRAP) by Silke Fähnrich, Anne Wedemann, Laura Steenpass, Wilhelm Gerhard Dirks

“…The strict suppression of telomerase activity (TA) in terminally differentiated human cells causes a shortening of the chromosome ends after each cell division. This tumor suppression surveillance mechanism is associated with a limited number of cell divisions known as Hayflick limit. …”
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Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18 by Satish Kumar, Lingaraja Jena, Maheswata Sahoo, Mrunmayi Kakde, Sangeeta Daf, Ashok K. Varma

“…In the present study, we explored these natural compounds against E6 oncoprotein of high risk HPV18, which is known to inactivate tumor suppressor p53 protein. E6, a high throughput protein model of HPV18, was predicted to anticipate the interaction mechanism of E6 oncoprotein with these natural inhibitors using structure-based drug designing approach. …”
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Tube Thoracostomy: Complications and Its Management by Emeka B. Kesieme, Andrew Dongo, Ndubueze Ezemba, Eshiobo Irekpita, Nze Jebbin, Chinenye Kesieme

“…Technical causes include tube malposition, blocked drain, chest drain dislodgement, reexpansion pulmonary edema, subcutaneous emphysema, nerve injuries, cardiac and vascular injuries, oesophageal injuries, residual/postextubation pneumothorax, fistulae, tumor recurrence at insertion site, herniation through the site of thoracostomy, chylothorax, and cardiac dysrhythmias. …”
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Concentrations of Selected Adipokines, Interleukin-6, and Vitamin D in Patients with Papillary Thyroid Carcinoma in Respect to Thyroid Cancer Stages by Jakub Warakomski, Ewa Romuk, Barbara Jarząb, Jolanta Krajewska, Lucyna Siemińska

“…No significant relationships between serum concentrations of leptin, adiponectin, chemerin, IL-6, vitamin D, and tumor size in PTC were found. Although insulin resistance represented by the HOMA index was associated with anthropometric variables and with serum leptin, adiponectin, chemerin, and IL-6 concentrations, in our study, no statistically significant relations with PTC staging were identified.…”
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Prevalence of oral side effects associated with chemo and radiotherapy in head and neck cancer treatment: A cross-sectional study in Egypt by Dalia Mohamed abo el Fadel, Yasmine Kamal, Ashraf Hamed Hassouna, Amal Ali

“…Conclusion: Head and neck cancer patients suffer from severe oral side effects influenced by the treatment modality and stage of the tumor affecting their quality of life.…”
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Anticancer effects of PEP06 (TB01) in combination with Trifluridine/Tipiracil (TAS-102) in a xenograft model of human colorectal cancer by Ruohong Lin, Jiaxing Cheng, Jinlong Zhao, Liang Zhou, Jian Li, Xinchun Yang

“…Results The combination therapy not only demonstrated significantly inhibited tumor growth in a dose-dependent manner, but also seems to reduce the common toxicity associated with such treatments, as shown by the maintenance of body weights in the treated mice. …”
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Bridging Molecular Docking to Molecular Dynamics to Enlighten Recognition Processes of Tailored D-A/D-A-D Types' AIEgens with HSA/BSA by Harun Nalçakan, Gülbin Kurtay

“…Fluorescence imaging-assisted photodynamic therapy (PDT) allows accurate tumor visualization and potentially prevents long-term side effects of cancer. …”
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Unraveling the PVTGlu-mPFCGlu circuit: A new frontier in chronic pain management for bone cancer pain by Liqun Duan, Qianliang Wang, Jianpeng Chen, Zelin Fan, Wenzhi Zhang, Jun Yan

“…Bone cancer pain (BCP) is a type of ongoing or breakthrough pain caused by a primary bone tumor or bone metastasis. BCP impairs patients’ quality of life. …”
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Prediction model establishment of prognosis factors for acute myeloid leukemia based on the SEER database by Gangping Li, Di Zhang, Yuewen Fu

“…The nomogram was developed using key variables including age, race, first primary tumor, and chemotherapy. The concordance indices (C-indices) were 0.704 for OS and for 0.686 for CSS. …”
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Influence of Medication on Flare Up and Infection After Elective Orthopedic Surgery in Rheumatoid Arthritis Patient – A Narrative Review by Yaldi Rosadi, Yustin Marinta, Muthiah Nur Afifah

“…On the use of bDMARD, 37.0% of patients had higher surgical site infection (SSI). Specifically, Tumor Necrosis Factor-alpha (TNF-α) inhibitors significantly (OR: 9.5, 95% CI: 1.0-88.8) increase the incidence of postoperative infections in standard-dose and high-dose, but not significantly in the rate of flares. …”
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Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer by Sung Hoo Kim, Byung Kyu Ahn, Seung Sam Paik, Kang Hong Lee

“…Elevated COX-2 expression in itself is not a prognostic factor, but COX-2 expression in tumor tissue may be an independent predictive marker of late recurrence for patients with stage I to III CRC.…”
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Evaluation of the Effects of Different Bacteroides vulgatus Strains against DSS-Induced Colitis by Sijia Li, Chen Wang, Chengcheng Zhang, Yanhong Luo, Qianqian Cheng, Leilei Yu, Zhen Sun

“…In contrast, B. vulgatus 51K1 significantly worsened the DSS-induced alterations in the tumor necrosis factor-alpha (TNF-α) concentration and colonic histopathology. …”
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THE FREQUENCY OF TESTICULAR LESION IN ATERTIARY CARE CENTER by Prih Bashir, Noshaba Rahat, Humera Shahzad, Asma Jalbani, Farhana Zulfiqar, Bhawani Shankar

“…Among neoplastic lesions, seminoma (7; 4.8%) was the most frequent, followed by mixed germ cell tumor (5; 3.4%). Conclusion: Overall, our results show that the prevalence of testicular non-neoplastic lesions is higher than that of testicular neoplasms. …”
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The Diagnostic and Prognostic Value of Kinesin-4A Protein, β-Tubulin Protein, and Exosomes as Non-Invasive Biomarkers in Iraqi Women with Breast Cancer by Samar Hasan Shammar, Hiba Resheed Behayaa, Ahmed F. F. Al-Baaj, Mohammed M. Ewadh, Sura Abd Zaid, Muna M. Ewadh, Mufeed Jalil Ewadh

“…Various circulating biomarkers and tumor markers were investigated including liver function test. …”
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Low grade mucoepidermoid carcinoma arising from glandular odontogenic cyst: A case report with a brief literature review by Spoorti Kulkarni, Adarsh Kudva, G. Srikanth, Vyshak Mohan, Mugdha Francis, Sunitha Carnelio

“…Low-grade mucoepidermoid carcinoma (MEC) is a salivary gland tumor arising rarely within the jaw bones. It poses a diagnostic challenge due to its considerable overlap of the histopathological features with Glandular odontogenic cyst (GOC). …”
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Involvement of PPARs in Cell Proliferation and Apoptosis in Human Colon Cancer Specimens and in Normal and Cancer Cell Lines by G. Martinasso, M. Oraldi, A. Trombetta, M. Maggiora, O. Bertetto, R. A. Canuto, G. Muzio

“…“In vitro” PPARγ and PPARα were evaluated in human tumor and normal cell lines, treated with natural or synthetic ligands. …”
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UMBILICAL RECONSTRUCTION WITH DOUBLE OPPOSING SEMILUNAR FLAP, AN APPEALING RESULTS: A CASE SERIES by Arif Rahmat Muharram, Agus Santoso Budi, Lobredia Zarasade, Beta Subakti Nata’atmadja

“…Along with its technical detail, we will present three cases comprises of the defect after omphalocele scar removal, umbilical endometriosis excision and postcentral abdominal tumor excision. Reports will be presented with preoperative and postoperative result. …”
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A Gamut of Astounding Diagnosis as Paraganglioma of Urinary Bladder: A Retrospective Study from North India by Nazia Manzoor Walvir, Aiffa Aiman, Inara Abeer, Mohammad Iqbal Lone, Shadab Maqsood

“…Background and Aim: Urinary bladder paraganglioma (UBPGL) is a rare neuroendocrine neoplasm, accounting for <0.05% of all bladder tumors and 0.7% of all paragangliomas. This study aimed to describe the histopathology of UBPGL, emphasizing the histologic attributes that may help pathologists recognize this rare bladder tumor and aid in differentiation from urothelial malignancies and other tumors that may resemble paragangliomas. …”
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Ameloblastic Fibro-Odontoma: A Diagnostic Challenge by Elen de Souza Tolentino, Bruna Stuchi Centurion, Marta Cunha Lima, Patrícia Freitas-Faria, Alberto Consolaro, Eduardo Sant'ana

“…The diagnosis was ameloblastic fibro-odontoma, which is a rare mixed odontogenic tumor, derived from epithelial and ectomesenchymal elements that form the dental tissues.…”
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Therapeutic Targeting of MOAP-1 in Cancer: A Systematic Review of Current Approaches and Future Directions by Xinwei Koong, Keyun Look, Amar Daud Iskandar Abdullah, Kuan Onn Tan, Vasudevan Mani, Hooi-Leng Ser, Khang Wen Goh, Ali Saleh Alkhoshaiban, Long Chiau Ming

“…The intricate control of MOAP-1 in cancer highlights the need for more research to understand its function and regulation across cancer types completely. MOAP-1's tumor suppressor activity suggests it could be a therapeutic target, as evidenced by current research findings, which is likely to spur further research into MOAP-1-targeted cancer treatments. …”
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