Human Urinary Kallidinogenase Reduces Lipopolysaccharide-Induced Neuroinflammation and Oxidative Stress in BV-2 Cells by Zhongyan Zhao, Zhiyu Xu, Tao Liu, Shixiong Huang, Huai Huang, Xiaoyun Huang

“…Cell viability of BV-2 cells was tested by the CCK-8 assay. Expressions of tumor necrosis factor-α (TNFα), prostaglandin E2 (PGE2), interleukin-6 (IL-6), and interleukin-1β (IL-1β) were examined with the ELISA method and western blot. …”
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A Rare Case of Perforated Descending Colon Cancer Complicated with a Fistula and Abscess of Left Iliopsoas and Ipsilateral Obturator Muscle by Alban Cacurri, Gaspare Cannata, Stefano Trastulli, Jacopo Desiderio, Antongiulio Mangia, Olga Adamenko, Eleonora Pressi, Giorgio Giovannelli, Giuseppe Noya, Amilcare Parisi

“…It proceeded with an exploratory laparotomy that showed a tumor of the descending colon adhered and perforated in the retroperitoneum with abscess of the iliopsoas muscle on the left-hand side, with presence of a fistula and liver metastases. …”
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SEDACIÓN Y ANALGESIA CON BOLOS DE XILAZINA Y MORFINA EN INFUSIÓN CONTINUA EN UNA YEGUA CRIOLLA COLOMBIANA SOMETIDA A OVARIOECTOMÍA EN ESTACIÓN by D. A. Zuluaga, D. Duque, J. D. Ruiz, I. Ruiz, T. Escobar, M. C. Ochoa

“…En el presente caso clínico se evaluó un protocolo de bolos de xilazina 0,6 mg/kg I.V. y morfina en infusión I.V. continua a 30 µg/kg/hora, con aplicación de anestesia local para la extraccción de un tumor de células de la granulosa en una yegua. Durante el procedimiento quirúrgico se observó una buena analgesia, sedación moderada y ataxia leve, sin alteraciones cardiovasculares o respiratorias, lo que favoreció el procedimiento quirúrgico; solamente se observó un corto periodo de amotilidad intestinal el cual fue superado espontáneamente. …”
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Circ_0089761 accelerates colorectal cancer metastasis and immune escape via miR‐27b‐3p/PD‐L1 axis by Qizhong Gao, Xiaowei Cheng, Xiang Gao

“…Furthermore, the high expression of circ_0089761 was correlated with TNM stage and tumor size. Silencing circ_0089761 inhibited CRC cell proliferation, migration, and invasion, and increased apoptosis. …”
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Repurposing Drugs in Controlling Recurrent Platinum-Resistant Clear-Cell Ovarian Cancer by Woraporn Sinsuwan, Phawit Norchai

“…Two months after therapy, a computerized tomography (CT) scan revealed a conflict between a decline in tumor marker levels (CA 125, CA 19-9) and an increase in the number of lymph nodes. …”
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Ischemia Elicits a Coordinated Expression of Pro-Survival Proteins in Mouse Myocardium by Deborah Lyn, Shaojia Bao, Nicole A. Bennett, Xiaowei Liu, Nerimiah L. Emmett

“…In contrast, a deficiency of xIAP expression was found in cardiac infarcts starting after 1 week, concomitant with significant evidence of apoptotic cell death and an up-regulation of pro-apoptotic signals including Bax, tumor necrosis factor-a, and caspase-8 activation. …”
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Use of a Ray-Based Reconstruction Algorithm to Accurately Quantify Preclinical MicroSPECT Images by Bert Vandeghinste, Roel Van Holen, Christian Vanhove, Filip De Vos, Stefaan Vandenberghe, Steven Staelens

“…The in vivo quantification error was determined for two radiotracers: [ 99m Tc]DMSA in naive mice ( n = 10 kidneys) and [ 111 In]octreotide in mice ( n = 6) inoculated with a xenograft neuroendocrine tumor (NCI-H727). The measured energy resolution is 5.3% for 140.51 keV ( 99m Tc), 4.8% for 171.30 keV, and 3.3% for 245.39 keV ( 111 In). …”
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Hypoxia Promotes Glioma Stem Cell Proliferation by Enhancing the 14-3-3β Expression via the PI3K Pathway by Weidong Cao, Qiang Zhou, Hongwei Wang, Wei Rao, Gang Cheng, Peng Wang, Shengli Guo, Bin Ren, Jianning Zhang

“…Furthermore, hypoxia promoted GSC cell proliferation and activated the expression of proliferating cell nuclear antigen, which was inhibited following 14-3-3β knockdown. In addition, tumor growth in mice was enhanced by CoCl2 application but reversed following 14-3-3β knockdown, which also enhanced GSC cell apoptosis. …”
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Role of exhaled hydrogen sulfide in the diagnosis of colorectal cancer by Jian Chen, Yujen Tseng, Peizhun Du, Pengcheng Liu, Huilu Zhang, Guangjian Huang, Cheng’en Hu

“…The exhaled H2S in patients with CRC was correlated with gender, lesion location and tumour progression, including depth of invasion, lymphatic metastasis and TNM (Tumor, Lymph Nodes, Metastasis) staging.Conclusion Exhaled H2S analysis is a convenient and non-invasive detection method for diagnosing CRC, suggesting a potential role in population screening for CRC.…”
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Small Cell Neuroendocrine Carcinoma of the Urinary Tract Successfully Managed with Neoadjuvant Chemotherapy by Mustapha Ahsaini, Omar Riyach, Mohammed Fadl Tazi, Mohammed Jamal El Fassi, My Hassan Farih, Hind Elfatmi, Afaf Amarti

“…Following a diagnosis of small cell neuroendocrine carcinomas of the ureter and the bladder, thoracoabdominal-pelvic CT was done, and the staging of the tumor was done in the bladder (T2N0M0) and (T1N0M0) in the ureter. …”
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Prevalence of low bone mineral density in ankylosing spondylitis, correlation with disease activity, and serum sclerostin levels by Anupam Wakhlu, Akhil Pawan Goel, Puneet Kumar

“…OP expressed as reduced bone mineral density (BMD) is a common complication in AS. Tumor necrosis factor-α (TNF-α) causes induction of Dickkopf-1 and sclerostin, which downregulates bone formation by inhibiting wingless proteins and bone morphogenic proteins. …”
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Ethanol Extract of Ampelopsis brevipedunculata Rhizomes Suppresses IgE-Mediated Mast Cell Activation and Anaphylaxis by Ji-Yeong Park, Min-Jong Kim, Young-Ae Choi, Seung Woong Lee, Soyoung Lee, Yong Hyun Jang, Sang-Hyun Kim

“…In addition, ABE downregulated the tumor necrosis factor-α and interleukin-4 by suppressing the activation of nuclear factor-κB. …”
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Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent on Culture Conditions by Sabine Schröder, Stephan Kriesen, Daniel Paape, Guido Hildebrandt, Katrin Manda

“…In contrast to high-dose irradiation given to tumor patients, little is known about radiobiological mechanisms underlying this clinical successful LD-RT application. …”
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Retroperitoneal Extraovarian Fibrothecoma Mimicking a Malignant Epithelial Ovarian Carcinoma by Patrick Roberts, Sharon Nofech-Mozes, Natalie Coburn, Paul Hamilton, Lilian T. Gien

“…Fibrothecomas are benign sex cord-stromal tumors which rarely originate outside of the ovary. …”
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Radiomics of magnetic resonance imaging for assessment of pathological complete response to neoadjuvant therapy and long-term survival in breast cancer by N. V. Petrova, G. G. Karmazanovsky, E. V. Kondratyev, A. Yu. Popov, M. V. Rostovtsev, N. Yu. Germanovich, D. V. Kalinin

“…The use of neoadjuvant drug therapy increases the likelihood of achieving a complete pathomorphological response (pCR), leads to an increase in resectability and ablation; helps to determine the sensitivity of tumor cells to chemopreventive agents, thereby improving the patient’s prognosis. …”
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E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells by Bo Tan, Jingwei Zhang, Wen Wang, Haibo Ma, Yuanyuan Yang

“…Sphere formation assay, colony formation assay, and flow cytometry were performed to examine self-renewal ability, survival, and apoptosis of NSCLC stem cells. An animal model of tumor xenograft was developed in nude mice to observe the tumorigenic ability and radiation resistance of NSCLC stem cells. …”
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Primary Cardiac Angiosarcoma: A Fatal Disease by L. Antonuzzo, V. Rotella, F. Mazzoni, L. Doni, D. Bianchini, F. Garbini, V. Maio, F. Di Costanzo

“…A 42-year-old man with a cardiac tamponade underwent an urgent pericardiotomy that showed tumoral tissue, covering the surface of the right atrium. …”
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Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression by Marta Rico-Pereira, Fernando Muñoz-Hernández

“…Urgent surgery was performed: a pterional craniotomy with partial tumor removal and optic nerve decompression with extradural anterior clinoidectomy. …”
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Innate immune cells in vascular lesions: mechanism and significance of diversified immune regulation by Jinjing Wu, Yulu Qian, Kuang Yang, Shuhua Zhang, Erming Zeng, Daya Luo

“…This review provides a theoretical basis for addressing aberrant angiogenesis in disease processes or finding new antiangiogenic immune targets in inflammation and tumor.…”
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MANDİBULADA GÖRÜLEN SANTRAL DEV HÜCRELİ GRANÜLOMUN SİSTEMİK KALSİTONİN UYGULAMASI İLE TEDAVİSİ: BİR OLGU SUNUMU by Bozkurt Kubilay Işık, Özgür Hilal Erinanç, Doğan Dolanmaz, Nagehan Burcu Bayrak

“…Bu olgu raporunda 11 yaşında erkek hastanın, mandibular molar bölgesinde teşhis edilen SDHG’ ye tedavi yaklaşımından bahsedilecektir.Gereç ve Yöntemler:Hasta klinik ve radyolojik değerlendirildikten sonra, hiperparatiroidizmin (brown tumor) elimine edilmesi için kan testi de yaptırılmış ve kan değerleri normal bulunmuştur. …”
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