Retracted: Computer Medical Image Segmentation Based on Neural Network by Xiaopeng Wang, Lei Gu, Zhongyi Wang

“…We then applied the method to a computer-aided system to classify tumor lesions in mammograms. Finally, we propose an FPGA-based multilevel optimization architecture for energy-efficient cellular neural networks. …”
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Platelet-Rich Gel Supernatants Stimulate the Release of Anti-Inflammatory Proteins on Culture Media of Normal Equine Synovial Membrane Explants by Diana L. Ríos, Catalina López, Jorge U. Carmona

“…The aims were as follows: (1) to evaluate the effects at 48 and 96 h of two concentrations (25 and 50%) of leukocyte and platelet-rich gel (L-PRG) and pure PRG (P-PRG) supernatants on the production/degradation in normal equine synovial membrane explants (SME) of platelet derived growth factor isoform BB, transforming growth factor beta-1, tumor necrosis factor alpha, interleukin (IL-) 4 (IL-4), IL-1 receptor antagonist (IL-1ra), and hyaluronan (HA) synthesis and (2) to correlate these molecules with their respective PRG supernatant treatments. …”
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Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Defects in the generation and metabolism of ceramide in cancer cells contribute to tumor cell survival and resistance to chemotherapy. …”
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Evaluating the Influence of Hashimoto’s Thyroiditis on Clinico-Pathological Characteristics and Prognostic Outcomes of Middle Eastern Differentiated Thyroid Carcinoma by Sandeep Kumar Parvathareddy, Abdul K. Siraj, Nabil Siraj, Saeeda O. Ahmed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya

“…Univariate analysis revealed a positive correlation between presence of HT and clinico-pathological factors such as female gender, younger age, and early stage tumor. In contrast, HT demonstrated a negative association with several aggressive clinical features, including extrathyroidal extension, distant metastasis, recurrent/persistent disease and high-risk categorization by the American Thyroid Association (ATA) guidelines. …”
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Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer by Ke Zhu, Wen Deng, Hui Deng, Xiaoqiang Liu, Gongxian Wang, Bin Fu

“…GSEA analysis indicated that PPAR signature was implicated in multiple oncogenic signaling pathways and correlated with tumor immune cell infiltration. Patients in the high-risk groups showed greater sensitivity to chemotherapy than those in the low-risk groups. …”
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Reaction of the Liver upon Long-Term Treatment of Fluoxetine and Atorvastatin Compared with Alcohol in a Mouse Model by Zhiliang Chen, Tony C. H. Chow, Shicong Wang, Gigi C. T. Leung, Sharon L. Y. Wu, David T. Yew

“…Comparisons of animals treated with the three drugs were carried out: serum aspartate transaminase (AST), alanine transaminase (ALT), and albumin were measured; liver tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta-1) levels were evaluated; proliferative cells were detected via immunohistochemistry (IHC) targeting on proliferating cell nuclear antigen (PCNA) and minichromosome maintenance complex component 2 (MCM2); for apoptosis, IHC targeting on activated caspase-3 and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) were employed; and histopathology was also documented in all groups. …”
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Navigating the frontier: Comprehensive insights into CRISPR technology advancements, delivery strategies, and ethical considerations in cancer research by Manisha S. Jain, K.S. Srikruthi, Prakash Goudanavar, N Raghavendra Naveen

“…The discussion extends to the burgeoning field of tumor research modeling using CRISPR, shedding light on its potential applications and challenges. …”
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Computational and Biological Comparisons of Plant Steroids as Modulators of Inflammation through Interacting with Glucocorticoid Receptor by Mohamed A. Morsy, Snehal S. Patel, Azza A. K. El-Sheikh, Jignasa K. Savjani, Anroop B. Nair, Jigar N. Shah, Katharigatta N. Venugopala

“…All tested compounds interacted with GR, but only boswellic acid and withaferin A showed docking results comparable to fluticasone, as well as similar in vivo anti-inflammatory effects, by significantly decreasing serum levels of interleukin-6 and tumor necrosis factor-α in cotton pellet-induced granuloma in rats. …”
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Long-Term Survival of More than 5 Years with Maintenance Therapy Using Single-Agent Pemetrexed in a Patient with Diffuse Malignant Peritoneal Mesothelioma by Yasuo Otsuka, Yoriaki Komeda, Masayuki Takeda, Takayuki Takahama, Masashi Kono, Mamoru Takenaka, Satoru Hagiwara, Naoshi Nishida, Hiroshi Kashida, Masatoshi Kudo

“…Histopathological examination of a biopsy specimen revealed peritoneal invasion of atypical epithelioid cells with trabecular and glandular patterns. The tumor cells were positive for AE1/AE2, calretinin, WT-1, D2-40, HEG1, EMA, BAP1, and MTAP and negative for carcinoembryonic antigen, MOC-31, Ber-Ep4, ER, PgR, TTF-1, claudin 4, and desmin. …”
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The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology by Bart Krist, Urszula Florczyk, Katarzyna Pietraszek-Gremplewicz, Alicja Józkowicz, Jozef Dulak

“…On the other hand, modulating the expression of proangiogenic factors such as vascular endothelial growth factor, angiopoietin-1, or interleukin-8, influencing inflammatory reaction, and affecting tumor suppressors, such as SuFu and Fus-1, miR-378a is considered as a part of an angiogenic network in tumors. …”
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Euodiae Fructus: a review of botany, application, processing, phytochemistry, quality control, pharmacology, and toxicology by Yule Hao, Jiawen Qi, Xinggui Huang, Chenhao Liu, Yi Liu

“…So far, more than 300 metabolites have been extracted and identified from EF, exhibiting various pharmacological effects, such as cardiovascular protection, gastrointestinal protection, neuroprotection, anti-inflammation, analgesia, anti-tumor, glucose and lipid metabolism regulation, etc. …”
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p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis. by Özgün Le Roux, Jeffery I Everitt, Christopher M Counter

“…Both the percentage of mice with lung tumors and total number of adenomas per animal were unchanged. …”
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Acute Myelogenous Leukemia with the t(7;7)(p15;p22) Translocation, a Novel Simple Variant of t(7;11)(p15;p15) Translocation: First Description by Motoharu Shibusawa

“…Flow cytometry CD45 gating revealed that the blasts expressed CD34, CD13, CD33, and CD117. G-banding of tumor cells revealed the t(7;7)(p15;p22) translocation [20/20]. …”
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The IL-10/STAT3 Axis Nasopharyngeal Carcinoma Cancer stem cell and radio resistance by Li-jun Wang, Ying Zhao, Yan-sheng Wang, Lei Xing, Yun-jing Duan, Huan-huan Zang

“…Abstract One of the primary reasons for the failure of therapy in nasopharyngeal cancer (NPC) is radio resistance-related localized one, which may lead to tumor residuals or recurrences. Several studies have linked interleukin-10 (IL-10) to crucial functions in cancer development and response to therapy. …”
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Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation by Betsy J. Evans, Dorian O. Haskard, Gregory Sempowksi, R. Clive Landis

“…Multiplex cytokine analysis demonstrated that monocyte chemoattractant protein (MCP-1/CCL2), interleukin- (IL-) 6, IL-8/CXCL8, macrophage inflammatory protein (MIP1α/CCL3), MIP-1β/CCL4, tumor necrosis factor- (TNF-) α, and eotaxin (CCL11) were all significantly upregulated at 16 h compared with 40 h. …”
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Computer Simulation on Analgesic Functional Chemome Characteristics of <italic>Radix Saposhnikoviae</italic> by Chunsong ZHENG, Xiaojie XU, Hongzhi YE, Jinxia YE, Guangwen WU, Xianxiang LIU

“…Objective:To investigate analgesic functional chemome characteristics of <italic>Radix Saposhnikoviae</italic> (RS), and provide information on molecular basis for clinical application of RS in Bi syndrome therapy.Methods:The chemical components of RS were retrieved from <italic>the Handbook of the Constituents in Chinese Herb Original Plants</italic> and other literatures, and the molecular dataset of RS was constructed for computer simulation. Tumor necrosis factor alpha (TNF-α), p38, inducible nitric oxide synthase (iNOS) and phosphodiesterase 4A (PDE-4A) were considered as analgesic targets. …”
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Late Onset Graft Plasmacytoma-Like PTLD Presenting as Acute Hyperglycemia in a Kidney-Pancreas Transplant Recipient by P. Ventura-Aguiar, M. T. Cibeira, A. Martinez, M. Cuatrecasas, M. Aymerich, J. Ferrer, J. Blade, F. Diekmann, M. J. Ricart

“…PET-scan FDG uptake was limited to pancreas allograft. Tumor origin could not be established (using DNA microsatellite analysis). …”
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Isolated Infra-Orbital Nerve Schwannoma by Debjyoti Mallick, Saumitra Kumar, Rojan Ravi, Ankita Atin Mukherjee

“… Introduction- A schwannoma is a benign tumor that develops from Schwann cells. It’s known to occur more frequently in women than men, and about one third occur in the head & neck area. …”
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Comparative Analysis of US Guidelines for the Management of Cutaneous Squamous Cell and Basal Cell Carcinoma by Amit Mittal, Bharat B. Mittal

“…A comprehensive comparison was performed in the following clinical interest areas: staging and risk stratification, management of primary tumor and regional nodes with curative intent, and palliative treatment. …”
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Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation by Vikas Nath, Mithra Baliga, Jack Lewin, Frederico Souza, Israh Akhtar

“…The patient later underwent radical nephrectomy; histologic sections of the resected tumor revealed an encapsulated lesion morphologically similar to the biopsy specimen. …”
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