A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells... by Federica De Castro, Erika Stefàno, Erik De Luca, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…NMR-based metabolomics is a very effective tool to assess the tumor response to drugs by providing insights for their mode of action. …”
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Spinous Process Osteochondroma as a Rare Cause of Lumbar Pain by Bárbara Rosa, Pedro Campos, André Barros, Samir Karmali, Esperança Ussene, Carlos Durão, João Alves da Silva, Nuno Coutinho

“…Marginal resection of the tumor was performed through a posterior approach. …”
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LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression by Hua Guo, Jing Li, Furong Fan, Ping Zhou

“…Then, we assessed the detailed effect of LINC00707 on the development of cervical cancer using CCK-8 assay, Transwell assays, and tumor xenograft experiments. Gain-of-function and loss-of-function assays revealed the function of LINC00707 in cervical cancer progression. …”
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Effect of Oral and Vaginal Hormonal Contraceptives on Inflammatory Blood Biomarkers by Afshin A. Divani, Xianghua Luo, Yvonne H. Datta, James D. Flaherty, Angela Panoskaltsis-Mortari

“…We assessed the effect of hormonal contraceptive use on inflammatory cytokines including CRP, monocyte chemotactic protein-1, soluble tumor necrosis factor (sTNF), interleukin-6 (IL-6), and soluble CD40 ligand. …”
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Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis by Tao Jiang, Jinhong Xu, Yang Lu, Xiaojin Chen, Yongxia Li

“…The inflammatory factor tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), and interleukin 6 (IL-6) in a dose-dependent manner were decreased. …”
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Effects of Laminaria Japonica Polysaccharides on the Survival of Non-Small-Cell Lung Cancer A549 Cells by Mengxing Yao, XiaoJun Qian, Houying Qin

“…In vivo: a xenograft model was established to detect the tumor volume and mass and the expression of the above pathway proteins. …”
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The role of reaction temperature in synthesizing clove-derived copper oxide nanoparticles for brain cancer treatment by Mehrnoosh Fakhredin, Fatemeh Shariatmadar Tehrani, Maryam Aliannezhadi

“…Notably, CuO NPs obtained at a reaction temperature of 50°C exhibited better primary properties, facilitating their potential application in cancer treatment. Brain tumors constitute a disproportionately significant contributor to the overall cancer mortality burden, particularly in cases where surgical intervention is not a viable treatment option. …”
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GILT stabilizes cofilin to promote the metastasis of prostate cancer by Dunsheng Han, Zhiming Wu, Cong Zhang, Ziwei Wei, Fan Chao, Xuefeng Xie, Jinke Liu, Yufeng Song, Xiaoming Song, Dingchang Shao, Shiyu Wang, Guoxiong Xu, Gang Chen

“…While the involvement of GILT in the development of various tumors has been demonstrated, the mechanisms underlying its regulation in prostate cancer (PCa) are not fully understood. …”
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Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report by Hannah Haile, Pavan S. Upadhyayula, Esma Karlovich, Michael B. Sisti, Brian J. A. Gill, Laura E. Donovan

“…The evolving nature of these tumors requires persistent clinical monitoring and treatment adjustments based on tissue diagnostics.…”
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Dislocability of Localization Devices for Nonpalpable Breast Lesions: Experimental Results by David Kaul, Eva Fallenberg, Felix Diekmann, Volker Budach, Martin Maurer

“…For accurate resection of nonpalpable malignant breast lesions with a tumor-free resection rim, an exact and stable wire localization is essential. …”
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CXCL1-Triggered Interaction of LFA1 and ICAM1 Control Glucose-Induced Leukocyte Recruitment during Inflammation In Vivo by Kirsten Buschmann, Lutz Koch, Natascha Braach, Hanna Mueller, David Frommhold, Johannes Poeschl, Peter Ruef

“…We demonstrated that a single injection of glucose rapidly increased blood glucose levels in a dose-dependent manner. Notably, during tumor necrosis factor (TNF) α-induced inflammation leukocyte recruitment was not further enhanced by glucose administration, whereas glucose injection profoundly augmented leukocyte adhesion and transmigration into inflamed tissue in the trauma model, indicating that proinflammatory properties of glucose are stimulus dependent. …”
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A prognostic index model for predicting long-term recurrence of uterine leiomyoma after myomectomy. by Xiu Ming, Junying Zhou, Jinhai Gou, Na Li, Dan Nie, Luqi Xue, Zhengyu Li

“…<h4>Introduction</h4>Uterine leiomyoma (UL) is a common benign pelvic tumor in women that has a high recurrence rate. Our aim is to propose a prognostic index (PI) model for predicting the long-term recurrence risk of uterine leiomyoma (UL).…”
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Genetic advancements in breast cancer treatment: a review by Marzieh Shokoohi, Sadaf Sedaghatshoar, Homaira Arian, Milad Mokarami, Fatemeh Habibi, Fatemeh Bamarinejad

“…CRISPR/Cas9 enables precise gene editing to correct mutations in oncogenes like HER2 and MYC, directly addressing tumor growth and immune evasion. Simultaneously, OVT leverages genetically engineered viruses to selectively destroy cancer cells and stimulate robust antitumor immune responses. …”
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Metastatic Follicular Thyroid Carcinoma Secreting Thyroid Hormone and Radioiodine Avid without Stimulation: A Case Report and Literature Review by Syed A. Abid, Brendan C. Stack, Donald L. Bodenner

“…This case is exceptional because of its rarity and also due to the dissociation between tumor differentiation and aggressiveness. The metastatic lesions continued to secrete thyroid hormone and remained radioiodine avid with rapid progression after I-131 therapy.…”
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Apigenin is an anoikis sensitizer with strong anti-metastatic properties in experimental breast cancer by Ruijie Xu, Zhijie Yao, Hao Zhang, Haitao Li, Wei Chen

“…Phenotypically, apigenin sensitized breast cancer cells to anoikis, lowered the number of circulating tumor cells, and protected against breast cancer metastasis to lung in mice. …”
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Splenic Involvement in Hereditary Hemorrhagic Telangiectasia by Susumu Takamatsu, Kota Sato, Shunsuke Kato, Hiroto Nagano, Shunro Ohtsukasa, Yasuyuki Kawachi

“…Pathological examination of the resected specimen revealed that the hypervascular lesion of the spleen was not a tumor but was composed of abnormal vessels associated with hereditary hemorrhagic telangiectasia. …”
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Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects by Yufei Wang, Guangliang Li, Hanying Wang, Quan Qi, Xian Wang, Haiqi Lu

“…Overexpression of Nectin-4 has been observed in various tumors, including breast cancer, and is associated with tumor progression. …”
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Hypoglycemic effects of naturally processed Polygonum multiflorum extract in KK CgAy/J mice and its mechanism of action by Wenping Tang, Jianfeng Zhan, Shiming Li, Yue Liu, Chi-Tang Ho

“…The recent research effort of PM has been focused on antioxidant, anti-ageing and anti-tumor properties. In the present study, we utilized the traditional processing of harvested raw PM, and identified several stilbene components and then evaluated the potential anti-diabetic effects of the processed PM extract (PME). …”
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Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression by Georgia Tsaouli, Elisabetta Ferretti, Diana Bellavia, Alessandra Vacca, Maria Pia Felli

“…Also, the identification of the crosstalks in leukemia-stroma interaction within the tumor microenvironment may unveil new targetable mechanisms in disease relapse. …”
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Diagnostic and Predictive Recurrence Value of Plasma Fibrinogen in Patients With Adrenocortical Carcinoma by Chengquan Ma, Bin Yang, Quanzong Mao

“…Plasma fibrinogen levels and postoperative tumor recurrence information of the patients were also recorded. …”
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