Preclinical model for evaluating human TCRs against chimeric syngeneic tumors by Olivier Michielin, Philippe Guillaume, Melita Irving, Patrick Reichenbach, Vincent Zoete, Elise Gray-Gaillard, Evangelos Stefanidis, Aikaterini Semilietof, Julien Pujol, Alessia D'Esposito

“…A variety of approaches are being taken to augment tumor control by ACT including TCR affinity-optimization and T-cell coengineering strategies to address the suppressive tumor microenvironment (TME). …”
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Transition Yet Energy Consuming for Tumor Growth Regulated by the Colored Microenvironment by Leiyan Chen, Yan Wang, Qingqing Li, Haohua Wang

“…Transition or metastasis is a main characteristic of tumor developmental processes. However, the mechanism behind the transition and what costs involved are obscure when the tumor is exposed to a colored microscopic environment. …”
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Gastric Glomus Tumor: A Rare Cause of Upper Gastrointestinal Bleeding by Yoshinori Handa, Mikihiro Kano, Mayumi Kaneko, Naoki Hirabayashi

“…Histological and immunohistological analysis revealed the tumor to be a gastric glomus tumor. Gastric submucosal tumors remain challenging to diagnose preoperatively as they show a variety of radiologic and clinicopathologic features and are associated with the risk of bleeding upon biopsy, as is indicated in the guidelines for gastric submucosal tumors. …”
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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells by Amanda C. Stacer, Hanxiao Wang, Joseph Fenner, Joseph S. Dosch, Anna Salomonnson, Kathryn E. Luker, Gary D. Luker, Alnawaz Rehemtulla, Brian D. Ross

“…Tumor-initiating cells, also designated as cancer stem cells, are proposed to constitute a subpopulation of malignant cells central to tumorigenesis, metastasis, and treatment resistance. …”
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Tumor Mutation Signature Reveals the Risk Factors of Lung Adenocarcinoma with or Mutation by Jialiang Wang MM, Chang Guo BMed, Jiexiao Wang MM, Xiaopeng Zhang BS, Jian Qi PhD, Xiang Huang MM, Zongtao Hu MM, Hongzhi Wang MM, Bo Hong PhD

“…Introduction EGFR and KRAS mutations are frequently detected in lung adenocarcinoma (LUAD). Tumor mutational signature (TMS) determination is an approach to identify somatic mutational patterns associated with pathogenic factors. …”
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Person-centered support for patients with a pituitary tumor following surgery by Sofie Jakobsson, Oskar Ragnarsson, Tobias Hallén, David Krabbe, Ann-Charlotte Olofsson, Daniel S Olsson, Penelope Trimpou, Thomas Skoglund, Gudmundur Johannsson

Subjects: “…pituitary tumor…”
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Insights of Outcome after Resection of Small Nonfunctioning Neuroendocrine Pancreatic Tumors by Estela Regina Ramos Figueira, Julia Fray Ribeiro, Thiago Costa Ribeiro, Ricardo Jureidini, Guilherme Naccache Namur, Thiago Nogueira Costa, Telesforo Bacchella, Ivan Cecconello

“…The incidence of small nonfunctioning neuroendocrine pancreatic tumors (NF-PNETs) has been increasing systematically in the last few decades. …”
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Editorial: LncRNAs in tumor microenvironment: its role in immunoregulation and inflammation by Dipanjan Ghosh

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Primary orbital yolk sac tumor in an infant: A rare entity by Varsha Mishra, Sandeep Jain, Payal Malhotra, Garima Durga, Gauri Kapoor

Subjects: “…germ cell tumor…”
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Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game by Paqui G. Través, Alfonso Luque, Sonsoles Hortelano

“…The interaction between tumor progression and innate immune system has been well established in the last years. …”
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Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy by Shixue Chen, Lingling Li, Fan Zhang, Yu Wang, Yi Hu, Lei Zhao

“…This review considers various IgG-like BsAb generation approaches, summarizes the clinical applications of promising new BsAbs, and describes the mechanism of BsAbs in tumor therapy.…”
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Chimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and Prospects by Yelei Guo, Yao Wang, Weidong Han

“…Many studies have struggled to improve the clinical responses to and benefits of CART-cell treatment of solid tumors. In this review, the status quo of CART cells and their clinical applications for solid tumors will be summarized first. …”
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Preoperative mapping techniques for brain tumor surgery: a systematic review by Augusto Leone, Augusto Leone, Francesco Carbone, Francesco Carbone, Uwe Spetzger, Peter Vajkoczy, Giovanni Raffa, Flavio Angileri, Antonino Germanó, Melina Engelhardt, Thomas Picht, Thomas Picht, Antonio Colamaria, Tizian Rosenstock, Tizian Rosenstock

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Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma by Se Won Kim, Seung-Eun Lee, Young Lyun Oh, Seokhwi Kim, Sun Hee Park, Jae Hyeon Kim

“…Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. …”
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Leiomyoma of the palatine tonsil - report of a rare and unusual tumor at this site by Andleeb Abrari, Aarti Tyagi, Urmi Mukherjee

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Biphasic Malignant Pleural Mesothelioma Masquerading as a Primary Skeletal Tumor by James Benjamin Gleason, Basheer Tashtoush, Maria Julia Diacovo

“…Biphasic malignant pleural mesothelioma is a rare malignant tumor, usually presenting as a pleural-based mass in a patient with history of chronic asbestos exposure. …”
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Inflammatory myofibroblastic tumor of the right renal pelvis: A case report by Xiaorui Zhu, Xueli Dong, Hongzhou Sheng, Renbin Deng, Xianzhong Duan

Subjects: “…Inflammatory myofibroblastic tumor…”
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Primary Extramedullary Plasmacytoma of the Heart: A Rare Manifestation of Plasmacellular Tumor by Romagnoli Andrea, Coco Irene, Fusco Armando, Dominique De Vivo, Giovanni Simonetti

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Coexistence of Primary GEJ Adenocarcinoma and Pedunculated Gastric Gastrointestinal Stromal Tumor by Aroub Alkaaki, Basma Abdulhadi, Murad Aljiffry, Mohammed Nassif, Haneen Al-Maghrabi, Ashraf A. Maghrabi

“…Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive system, although they account for only 0.1–3% of all gastrointestinal (GI) malignancies. …”
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Case Report of Rare Parathyroid Tumor with Atypical Presentation and Early Diagnosis by Érika Mayumi Ikeda Cavamura, Fabiane Karen Miyake, Jéssica Yachio Wiezel, Laura Schwartz Maranho, Luis Felipe Inglês Takada, Renata Cassitas Mendonça, Tamila Sohn Fagundes

“…To raise the suspicion of parathyroid carcinoma, it is essential to perform the correlation of the clinical picture, biochemical values, and imaging exams, but to obtain the definitive diagnosis, intraoperative recognition of the tumor and the result of the histopathological examination of the resected tumor are necessary.…”
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