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3481
Hepatoid adenocarcinoma of the stomach with ideal response to neoadjuvant chemo-immunotherapy: a case report
Published 2025-01-01“…Computed tomography scans revealed substantial tumor regression. Subsequent radical surgical intervention confirmed significant tumor shrinkage, with no evidence of lymph node metastasis upon pathological examination. …”
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3482
Clinicopathological and prognostic factor analyses of primary fallopian tube carcinoma and high-grade serous ovarian cancer: a single-institution retrospective study
Published 2025-01-01“…OS was significantly related to FIGO stage, residual tumor size, and laterality. However, only residual tumor size was an independent prognostic variable for OS. …”
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3483
Alveolar Rhabdomyosarcoma of Nasopharynx and Paranasal Sinuses in Children Diagnosis and Treatment—Review of the Literature and Case Report
Published 2025-01-01“…Neuronavigation-guided functional endoscopic sinus surgery (FESS) is an effective option for achieving complete tumor excision, depending on tumor size and extent. …”
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3484
Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment
Published 2025-01-01“…In vivo anti-tumor results showed that HA/GCV@ZIF-8 accumulated in tumor cells and effectively inhibited tumor growth. …”
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3485
Metastatic pancreatic cancer now in remission: a case report and literature review
Published 2025-01-01“…Despite a stage IV diagnosis, the primary tumor was resected in order to mitigate the risk for mutation and progression. …”
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3486
Expression and prognosis of cellular senescence genes in head and neck squamous cell carcinoma
Published 2025-01-01“…Abstract Background Cellular senescence refers to cells entering a relatively stable state of cell cycle arrest, which is a barrier that tumor cells must cross to achieve immortalization and plays an extremely important role in preventing the occurrence and development of tumors. …”
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3487
Multi-omic and machine learning analysis of mitochondrial RNA modification genes in lung adenocarcinoma for prognostic and therapeutic implications
Published 2025-03-01“…Our findings uniquely link MRMS to increased tumor mutational burden, genetic instability, and an immunosuppressive tumor microenvironment characterized by reduced immune cell infiltration and elevated tumor purity. …”
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3488
Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence
Published 2024-12-01“…Breast cancer is a common malignant tumor of women. Ki67 is an important biomarker of cell proliferation. …”
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3489
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model
Published 2024-05-01“…Background Accumulating evidence demonstrates that an increased tumor-associated macrophage abundance is often associated with poor prognosis in colorectal cancer (CRC). …”
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3490
Preliminary in vitro evaluation of the anti-proliferative activity of guanylhydrazone derivatives
Published 2016-03-01“…Compounds 7, 11, 16 and 17 showed strong cytotoxic activity with IC50 values lower than 10 μmol L−1 against four tumor cell lines. Among them, 7 was less toxic to non-tumor cells. …”
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3491
The therapeutic potential of vitamins A, C, and D in pancreatic cancer
Published 2025-01-01“…This could contribute to the long-awaited progress in the treatment of this highly lethal tumor entity.…”
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3492
Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back
Published 2014-01-01“…Our hypothesis is that systemic delivery of VSVΔM51 can demonstrate tumor-specific killing of resistant EWS cells, as well as a significant decrease of tumor burden in EWS bearing mice. …”
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3493
Potentials of transanal endoscopic surgery at early rectal cancer
Published 2014-10-01“…Mean tumor size was 2,6±0,8 cm (1,0–4,0 cm). The average distance from the lower pole of tumor to outer edge of anal canal and to dentate line was 7,1±1,7 cm (4,0–9,0 cm) and 4,8±1,9 cm (1,5–7,0 cm) respectively. …”
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3494
Recurrent adenoid cystic carcinoma of the left upper palate accompanied by massive maxillary hemorrhage: a case report and literature review
Published 2025-01-01“…With the addition of radiotherapy and immune-targeted drug treatment, tumor progression was effectively controlled, leading to an improved quality of life for the patient, who successfully survived for 129 months with the tumor by July 2024. …”
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3495
Multidimensional Analysis of PANoptosis-Related Molecule CASP8: Prognostic Significance, Immune Microenvironment Effect, and Therapeutic Implications in Hepatocellular Carcinoma
Published 2023-01-01“…We conducted a comprehensive analysis using public data from the Cancer Genome Atlas, Human Protein Atlas, Tumor Immune Single Cell Hub, and STRING databases. …”
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3496
A Challenging Case of Metastatic Intra-Abdominal Synovial Sarcoma with Unusual Immunophenotype and Its Differential Diagnosis
Published 2012-01-01“…Intra-abdominal synovial sarcoma, either primary or metastatic, with unusual desmin positivity raises the diagnostic challenge, since a wide range of differential diagnoses could show a similar immunophenotype (leiomyosarcoma, desmoid tumor, myofibroblastic tumor, and rarely GIST etc.). …”
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3497
Position for Site-Specific Attachment of a DOTA Chelator to Synthetic Affibody Molecules Has a Different Influence on the Targeting Properties of Ga-Compared to In-Labeled Conjugat...
Published 2014-12-01“…The best 68 Ga-labeled variant was 68 Ga-[DOTA-A1]-Z HER2:S1 which provided a tumor uptake of 13 ± 1 %ID/g and a tumor to blood ratio of 39 ± 12 at 2 hours after injection. 111 In-[DOTA-A 1 ]-Z HER2:S1 and 111 In-[DOTA-K 58 ]-Z HER2:S1 were equally good at this time point, providing a tumor uptake of 15 to 16 %ID/g and a tumor to blood ratio in the range of 60 to 80. …”
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3498
Identification of novel therapeutic targets for head and neck squamous cell carcinoma through bioinformatics analysis
Published 2024-12-01“…Our results showed that WDR54, a member of the WD40 repeat domain family, was overexpressed in HNSCC tumor samples. Analysis of three gene expression omnibus datasets showed that WDR54 was overexpressed in tumor samples. …”
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3499
The Effect and Related Mechanism of Action of Astragalus Compatible with Curcumin against Colon Cancer Metastasis in Mice
Published 2022-01-01“…Colon cancer (CC) is the third most common tumor worldwide. Colon carcinogenesis is strongly linked to inflammation. …”
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3500
PEGylated Cisplatin Nanoparticles for Treating Colorectal Cancer in a pH-Responsive Manner
Published 2022-01-01“…Colorectal cancer (CRC) is a common malignant tumor, and its incidence ranks third and mortality rate ranks second in the world. …”
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