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3461
SegChaNet: A Novel Model for Lung Cancer Segmentation in CT Scans
Published 2022-01-01“…Accurate lung tumor identification is crucial for radiation treatment planning. …”
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3462
PPAR𝛾, PTEN, and the Fight against Cancer
Published 2008-01-01“…Activation of PPAR𝛾 through agonists increases functional PTEN protein levels that subsequently induces apoptosis and inhibits cellular growth, which suggests that PPAR𝛾 may be a tumor suppressor. Indeed, several in vivo studies have demonstrated that genetic alterations of PPAR𝛾 can promote tumor progression. …”
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3463
The Role of Targeted Therapy in Metastatic Renal Cell Carcinoma
Published 2007-01-01“…Renal cell carcinoma (RCC) is a highly vascular tumor in which a growing understanding of disease biology has been translated into clinically active systemic therapies. …”
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3464
Paraurethral Leiomyoma in a Postmenopausal Woman: First European Case
Published 2015-01-01“…Transvaginal ultrasound and MRI confirmed the tumor and excision of the paraurethral tumor was carried out. …”
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3465
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
Published 2010-01-01“…It seems that toll-like receptors (TLRs) as well as the nuclear factor (NF)-κB, and JNK pathways are critical regulators for the production of the cytokines associated with tumor promotion. The cross-talk between an inflammatory cell and a neoplastic cell, which is instigated by the activation of NF-κB and JNKs, is critical for tumor organization. …”
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3466
Rhabdomyosarcoma Orbita
Published 2019-09-01“…Rhabdomyosarcoma (RMS) merupakan tumor ganas pada jaringan lunak yang sering mengenai anak-anak. …”
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3467
Blasting neuroblastoma using optimal control of chemotherapy
Published 2009-05-01“…Numericalsimulations are given to demonstrate the behavior of the tumor and the immune systemcomponents represented in the model.…”
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3468
New insights into the mechanisms of the immune microenvironment and immunotherapy in osteosarcoma
Published 2025-01-01“…Osteosarcoma, a malignant bone tumor primarily affecting adolescents, is highly invasive with a poor prognosis. …”
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3469
Myofibroblastoma of the Breast: Literature Review and Case Report
Published 2016-01-01“…Myofibroblastoma of the breast is a rare benign spindle cell tumor. The main aim of this study is to review the literature of this rare tumor. …”
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3470
Immunotherapy: An Optimal Control Theory Approach
Published 2005-07-01“…We investigate mathematical models for the dynamics between tumor cells, immune-effector cells, and cytokine interleukin-2 (IL-2). …”
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3471
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3472
Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer
Published 2023-01-01“…Background The current challenge for immunotherapies is to generate effective antitumor immunity. Since tumor immune escape mechanisms do not impact pre-existing and consolidated immune responses, we tested the hypothesis of redirecting a pregenerated immunity to cancer: to recall a non-tumor antigen response against the tumor, silk fibroin nanoparticles (SFNs) have been selected as ‘Trojan-horse’ carriers, promoting the antigen uptake by the tumor cells.Methods SFNs have been loaded with either ovalbumin (OVA) or CpG oligonucleotide (CpG) as antigen or adjuvant, respectively. …”
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3473
Anti-PD-1 amplifies costimulation in melanoma-infiltrating Th1-like Foxp3+ regulatory T cells to alleviate local immunosuppression
Published 2025-01-01“…Background Immune checkpoint inhibitors targeting programmed cell death protein-1 (PD-1) are the first line of treatment for many solid tumors including melanoma. PD-1 blockade enhances the effector functions of melanoma-infiltrating CD8+ T cells, leading to durable tumor remissions. …”
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3474
Endobronchial Infection and Bacterial Lymphadenitis by Gemella morbillorum Leading to Airway Perforation and a Bronchopleural Fistula
Published 2024-01-01“…Conclusion: In cases of severe mediastinal adenopathy in a young patient, bacterial lymphadenitis should be considered in the differential diagnosis with lymphoma, germ cell tumor, granulomatosis with polyangiitis, sarcoidosis, histoplasmosis, and inflammatory myofibroblastic tumor.…”
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3475
Rare Cell Population Analysis in Early-Stage Breast Cancer Patients
Published 2025-01-01“…Sampling was conducted both before and after tumor resection. Methods: Linearity of the Rarmax platform was established using a spike-in approach. …”
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3476
Implantable Ultrasound‐Powered MXene/PVA Hydrogel‐Based Generator for Treatment of Glioblastoma
Published 2025-02-01“…In vitro and in vivo experiments confirmed the device's therapeutic effect, demonstrating a ≈92% inhibition rate in the growth of clinical tumor cells and a 73% reduction in tumor area in tumor‐bearing mice. …”
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3477
A Histologically Complete Response to Immunotherapy Using Pembrolizumab in a Patient with Giant Cell Carcinoma of the Lung: An Additional Report and Literature Review
Published 2019-01-01“…We previously reported a case of giant cell carcinoma in the lung, in which the use of antiprogrammed death 1 (PD-1) immunotherapy resulted in substantial tumor reduction. In the present study, we describe an additional clinical course. …”
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3478
Giant Parotid Pleomorphic Adenoma Involving Parapharyngeal Space
Published 2013-09-01“…<p>Abstrak<br />Latar belakang: Pleomorfik adenoma parotis merupakan tumor jinak kelenjar liur yang paling sering ditemukan, namun pleomorfik adenoma parotis yang sangat besar sehingga melibatkan ruang parafaring (RPF) sangat jarang. …”
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3479
Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells
Published 2013-01-01“…Evidence sustains a role for the acute-phase protein serum amyloid A (SAA) in carcinogenesis and metastasis, and the protein has been suggested as a marker for tumor progression. Nevertheless, the demonstration of a direct activity of SAA on tumor cells is still incipient. …”
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3480
TMEM101 expression and its impact on immune cell infiltration and prognosis in hepatocellular carcinoma
Published 2024-12-01“…The findings from CIBERSORT analysis suggest that TMEM101’s pro-tumor effect may be due to decreasing the number of anti-tumor immune cells (M1 macrophages and resting memory CD4+ T cells) and promoting M0 macrophage infiltration in the tumor microenvironment (TME). …”
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