Rab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression by Jing Wang, Xueying Yan, Wenfei Wang, Shu Wang, Hongxiang Jiang, Xinhua Zhu, Zhehui Li, Defu Cai, Yonggang Xia

“…Cytotoxicity, apoptosis, migration, and invasion experiments were used to evaluate the anti-tumor ability of the NDDS in vitro. The penetration and inhibition of tumor proliferation were further analyzed via a 3D tumor sphere model. …”
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MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

“…A deeper understanding of the interaction of cancer cells with other cells in the tumor microenvironment is crucial to devise effective therapeutic strategies. …”
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Radiolabeled Anti-Adenosine Triphosphate Synthase Monoclonal Antibody as a Theragnostic Agent Targeting Angiogenesis by Bok-Nam Park PhD, Su Jin Lee MD, PhD, Jung Hyun Roh MS, Kyung-Han Lee MD, PhD, Young-Sil An MD, PhD, Joon-Kee Yoon MD, PhD

“…In vivo biodistribution was evaluated 24 and 48 hours after intravenous injection of 125 I-ATPS mAb into MKN-45 tumor-bearing mice (n = 3). For radioimmunotherapy, 18.5 MBq 131 I-ATPS mAb (n = 7), isotype immunoglobulin G (IgG) (n = 6), and vehicle (n = 6) were injected into MKN-45 tumor-bearing mice for 4 weeks, and tumor volume and percentage of tumor growth inhibition (TGI) were compared each week. …”
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US-guided high-intensity focused ultrasound in pancreatic cancer treatment: a consensus initiative between Chinese and European HIFU centers by Kun Zhou, Holger Strunk, Dobromir Dimitrov, Joan Vidal-Jove, Maria A. Gonzalez-Carmona, Markus Essler, Chengbin Jin, Zhechuan Mei, Hui Zhu, Milka Marinova

“…Based on the ability of USgHIFU therapy to mitigate pain and reduce primary tumor volume, it should be considered as a complementary therapy for symptomatic patients with inoperable pancreatic cancer and as a potential means of tumor debulking. …”
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Immunogenic Targets for Specific Immunotherapy in Multiple Myeloma by Lu Zhang, Marlies Götz, Susanne Hofmann, Jochen Greiner

“…These antigens are expressed in a tumor-specific or tumor-restricted pattern, are able to elicit immune response, and thus could serve as targets for immunotherapy. …”
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Leiomyosarcoma in a dos by Zabid Yener, İsmail Alkan, Hayati Yüksel, Nazmi Atasoy

“…Tumor was grayish-white colored, solitary, subcutan, and had a lobular structure. …”
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Intraosseous Hemangioma of the Inferior Turbinate by Kazuya Takeda, Yukinori Takenaka, Michiko Hashimoto

“…The nasal cavity harbors an enormous variety of neoplasms, including epithelial and mesenchymal tumors. Hemangioma is an infrequent mesenchymal tumor of the nasal cavity, mostly arising in the mucosa and rarely in the bones. …”
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Novel combination strategy of high intensity focused ultrasound (HIFU) and checkpoint blockade boosted by bioinspired and oxygen-supplied nanoprobe for multimodal imaging-guided ca... by Ying Zhou, Chen Cheng, Qi Wang, Min Zheng, Pan Li, Yang Zhou, Yuting Cao, Li Wan, Xun Guo, Xiaohong Lin, Rui Tang, Hongye He, Nianhong Wu, Qiaoqi Chen, Yaqin Hu, Xialin Xiong, Faqi Li

“…Moreover, HIFU ablation alone may inevitably lead to the presence of residual tumors, which may cause tumor recurrence and metastasis. …”
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Plasmacytoid Urothelial Carcinoma of the Urinary Bladder Metastatic to the Duodenum: A Case Report—Diagnostic Relevance of GATA3 Immunohistochemistry by Hermann Brustmann

“…The patient died eleven months after the primary diagnosis of his PUC of tumor cachexia losing about 50% of his original body weight, furthermore, with ascites and intraperitoneal tumor spread.…”
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The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer by Ranjeeta Thapa, George D. Wilson

“…CD44 is a cell surface HA-binding glycoprotein that is overexpressed to some extent by almost all tumors of epithelial origin and plays an important role in tumor initiation and metastasis. …”
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Dedifferentiated Leiomyosarcoma of the Uterus with Heterologous Elements: A Potential Diagnostic Pitfall by Kojo R. Rawish, Oluwole Fadare

“…Dedifferentiation is a phenomenon that is well characterized in a variety of tumors and is defined by the occurrence of a high-grade or undifferentiated tumor, typically unrecognizable regarding its line of differentiation, from a low-grade/borderline neoplasm. …”
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Ovarian Basaloid Carcinoma with Shadow Cell Differentiation by Michal Zamecnik, Daniel Jando, Peter Kascak

“…Histologically, the tumor showed a pattern of high-grade basaloid carcinoma with numerous shadow cells. …”
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Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines by Petr G. Lokhov, Elena E. Balashova

“…Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium. …”
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Humoral Autoimmune Responses to Insulin-Like Growth Factor II mRNA-Binding Proteins IMP1 and p62/IMP2 in Ovarian Cancer by Xinxin Liu, Hua Ye, Liuxia Li, Wenjie Li, Yi Zhang, Jian-Ying Zhang

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Editorial: Ovarian cancer targeted medication: PARP inhibitors, anti-angiogenic drugs, immunotherapy, and more, volume II by Zhi-Bin Wang, Zhi-Bin Wang, Zhi-Bin Wang, De-Hua Liao, Guang Lei, Zhao-Qian Liu, Zhao-Qian Liu, Nayiyuan Wu, Nayiyuan Wu, Jing Wang, Jing Wang

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Elevated Preoperative Serum CA19-9 Levels in Patients with Hepatocellular Carcinoma Is Associated with Poor Prognosis after Resection by Yu-Ling Chen, Chien-Hung Chen, Rey-Heng Hu, Ming-Chih Ho, Yung-Ming Jeng

“…High serum CA19-9 levels did not correlate with patient age, sex, viral status, α-fetoprotein level, tumor size, tumor grade, tumor stage, multiplicity, and vascular invasion. …”
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Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations by Yingjun Xie, Yien Xiang, Jiyao Sheng, Dan Zhang, Xiaoxiao Yao, Yongsheng Yang, Xuewen Zhang

“…Traditional treatment methods for patients with hepatocellular carcinoma have shown poor efficacy in killing residual cancer cells for a long time. In recent years, tumor immunotherapy has emerged as a promising method owing to its safety and efficacy with respect to delaying the progression of advanced tumors and protecting postoperative patients against tumor relapse and metastasis. …”
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The anti-melanoma roles and mechanisms of tricholoma isoflavone derivative CA028 by Cheng Liang, Jianfu Jiang, Jinkai Li, Xiao Lin, Wenjun Huang, Keng Po Lai, Jian Chen

“…Cumulating evidence demonstrates that isoflavones exhibits significant anti-tumor properties and is beneficial for the prevention and treatment of melanoma. …”
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Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo by Song He, Ying-ze Wei, Gui-lan Wang, Yu-yin Xu, Jia-ming Zhou, Yi-xin Zhang, Li Chen

“…The mRNA levels of caspase-3, caspase-8, and caspase-9 of tumor tissues were reduced in different treatment groups compared with untreated group, particularly in combination group. …”
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A Giant Duodenal Leiomyoma Showing Increased Uptake on 18F-Fluorodeoxyglucose Positron Emission Tomography by Keisuke Nonoyama, Hidehiko Kitagami, Akira Yasuda, Shiro Fujihata, Minoru Yamamoto, Yasunobu Shimizu, Moritsugu Tanaka

“…Heterogeneous uptake was observed within the tumor on FDG-PET/CT. Based on these findings, the patient underwent surgery for suspected primary malignant lymphoma of the duodenum or gastrointestinal stromal tumor. …”
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