Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer by Christian Arstad, Kristin Taskén, Paulo Refinetti, Ulrika Axcrona, Karl-Erik Giercksky, Per Olaf Ekstrøm

“…Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with challenges regarding the initiation and advancement of the disease. …”
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Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway by Y. El Yousfi, F. J. Fernández-Farrán, F. J. Oliver, A. López-Rivas, R. Yerbes

“…Abstract In tumors, cancer cells are frequently exposed to adverse environmental conditions that result in endoplasmic reticulum (ER) stress. …”
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Treatment Effect of a Vascular-Disrupting Agent Dynamically Monitored by DWI: An Animal Experimental Study by Danping Huang, Ruimeng Yang, Yong Zou, Hongmei Lin, Xiangdong Xu, Xinhua Wei, Hanzheng Chang, Liqiong Wu, Wenshuang Ding, Wenjie Tang, Xinqing Jiang

“…B-value with 700 (s/mm2) was chosen during DWI examinations. Tumor volume and apparent diffusion coefficient (ADC) values of the entire tumor and solid component of the tumor at every time point were measured. …”
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Chondrosarcoma Arising from the Posterior Iliac Crest Extending into the Spinal Canal by Kota Wada, Akio Sakamoto, Rei Kato, Takashi Noguchi, Takayoshi Shimizu, Bungo Otsuki, Koichi Murata, Shunsuke Fujibayashi, Shuichi Matsuda

“…Chondrosarcoma is a malignant tumor characterized by the production of a cartilage matrix. …”
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Comparative the impact intraoperative phrenic nerve sacrifice on prognosis patients with thymoma by Hongyun Ruan, Xuehui Shang, Dongjie Yan, Bin Liu, Fangchao Liu, Zhi Yang

“…Abstract Objectives Complete removal of the tumor and surrounding tissue is the most important prognostic factor such as survival after surgery. …”
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A novel lncRNA AC112721.1 promotes the progression of triple-negative breast cancer by directly binding to THBS1 and regulating miR-491-5p/C2CD2L axis by Ping Ma, Shiyao Kang, Huimin Li, Ming Li, Yuan Zhao, Hongjun Yuan, Jianyu Pang, Wenru Tang, Miaomiao Sheng

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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, the number of MITF+ monocytic (MO)-MDSCs was examined in human tumor tissues or tumor-free lymph nodes by immunohistochemistry (IHC).Results The expression of MITF was strongly increased in MO-MDSCs from tumors of breast cancer-bearing mice compared with polymorphonuclear MDSCs. …”
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The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis by Gujun Cong, Jingjing Shao, Feng Xiao, Haixia Zhu, Peipei Kang

“…Abstract Background Endothelial cells are integral components of the tumor microenvironment and play a multifaceted role in tumor immunotherapy. …”
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Metabolic reprogramming in cancer: Mechanisms and therapeutics by Shiqi Nong, Xiaoyue Han, Yu Xiang, Yuran Qian, Yuhao Wei, Tingyue Zhang, Keyue Tian, Kai Shen, Jing Yang, Xuelei Ma

“…Metabolic reprogramming is a process mediated by various factors, including oncogenes, tumor suppressor genes, changes in growth factors, and tumor–host cell interactions, which help to meet the needs of cancer cell anabolism and promote tumor development. …”
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A proton therapy model using discrete difference equations with an example of treating hepatocellular carcinoma by Erin N. Bodine, K. Lars Monia

“…Specifically, the model simulates the growth and diffusion of the cancer and healthy cells in and surrounding a tumor over one spatial dimension (tissue depth) and the treatment of the tumor with discrete bursts of proton radiation. …”
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Characteristics and Prognostic Nomogram for Primary Lung Lepidic Adenocarcinoma by Hui Tang, Caixia Qiao, Yingyi Wang, Chunmei Bai

“…LPA was inclined to be smaller in tumor size and lower in tumor grade and staging, which may indicate a favorable prognosis. …”
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Imaging of Non— or Very Subtle Contrast-Enhancing Malignant Gliomas with [C]-Methionine Positron Emission Tomography by Norbert Galldiks, Lutz W. Kracht, Veronika Dunkl, Roland T. Ullrich, Stefan Vollmar, Andreas H. Jacobs, Gereon R. Fink, Michael Schroeter

“…In patients with World Health Organization (WHO) grade III glioma with a lack of or minimal (< 1 cm 3 ) magnetic resonance imaging (MRI) contrast enhancement, the volume of the metabolically active part of the tumor was assessed by [ 11 C]-methionine positron emission tomography (MET-PET). …”
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Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method by Madhuri Sankaranarayanapillai, William P. Tong, Qing Yuan, James A. Bankson, Hagit Dafni, William G. Bornmann, Suren Soghomonyan, Ashutosh Pal, Marc S. Ramirez, Douglas Webb, Kumaralal Kaluarachchi, Juri G. Gelovani, Sabrina M. Ronen

“…We extended our investigations to a tumor xenograft model. Following intraperitoneal injection of BLT, its accumulation within the tumor was monitored by in vivo 19 F MRS. …”
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Structural basis for tRNA mimicry by mascRNA and menRNA by Yuanlin He, Jie Deng, Xiaowei Lin, Zhizhong Lu, Liangliang Wang, Liang Xu, Yin Zhang, Jia Wang, Lin Huang

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Micro-PET Imaging of αβ-Integrin Expression with F-Labeled Dimeric RGD Peptide by Xiaoyuan Chen, Michel Tohme, Ryan Park, Yingping Hou, James R. Bading, Peter S. Conti

“…The α v integrins, which act as cell adhesion molecules, are closely involved with tumor invasion and angiogenesis. In particular, α v β 3 integrin, which is specifically expressed on proliferating endothelial cells and tumor cells, is a logical target for development of a radiotracer method to assess angiogenesis and anti-angiogenic therapy. …”
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Organoids and spheroids: advanced in vitro models for liver cancer research by Mirella Pastore, Alessia Giachi, Elena Spínola-Lasso, Fabio Marra, Chiara Raggi

“…They can be generated from pluripotent and adult stem cells, as well as from liver tumor specimens, providing personalized models for studying tumor behavior and drug responses. …”
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Intracranial Gliofibroma: A Case Report and Review of the Literature by Patricia Gargano, Graciela Zuccaro, Fabiana Lubieniecki

“…Gliofibroma is a rare tumor with biphasic morphology, commonly occurring in the first two decades of life. …”
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Analisis Ketahanan Hidup Lima Tahun Kanker Tiroid yang Dikelola di RSUP Dr. M. Djamil Padang by Oktahermoniza Oktahermoniza, Wirsma Arif Harahap, Tofriza Tofriza, Rosfita Rasyid

“…Pembahasan: Umur, ukuran tumor, dan jenis histopatologi memiliki hubungan bermakna dengan survival. …”
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Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer by Chunyan Liu, Yingying Zheng, Junyi Tang, Dawei Wang, Zhenshen Ma, Shutong Li, Xiaotian Chang

“…PADI4 has extensive expression in many tumors. This study applied PADI4 as a tumor marker to stimulate DC- (dendritic cell-) CIK (cytokine-induced killer), an immunotherapy approach. …”
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Associations of serum and tissue TIMP1 with host response and survival in colorectal cancer by Akseli Kehusmaa, Anne Tuomisto, Päivi Sirniö, Henna Karjalainen, Meeri Kastinen, Vilja V. Tapiainen, Ville K. Äijälä, Taina Tervahartiala, Timo Sorsa, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Markus J. Mäkinen, Juha P. Väyrynen

“…T cell densities in tumor tissue positively correlated with tumor stromal TIMP1 expression and negatively with tumor epithelial TIMP1 expression. …”
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