Showing 2,721 - 2,740 results of 10,572 for search '"Tumor"', query time: 0.11s Refine Results
  1. 2721
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  3. 2723

    Targeting the NOTCH2/ADAM10/TCF7L2 Axis‐Mediated Transcriptional Regulation of Wnt Pathway Suppresses Tumor Growth and Enhances Chemosensitivity in Colorectal Cancer by Zhen Xiang, Yiwei Wang, Xiao Ma, Shuzheng Song, Yuanqiao He, Jiamin Zhou, Longhai Feng, Su Yang, Yibin Wu, Bingran Yu, Guangkai Xia, Weiqi Xu, Yiming Zhao, Lu Wang

    Published 2025-01-01
    “…Through high‐throughput screening of 24 inhibitors on 12 CRC and three colorectal organoids in this organoid living biobank, adavivint is found to exhibit anti‐tumor activity and low toxicity in colorectal organoids, independent of the canonical Wnt/β‐catenin signaling. …”
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  4. 2724

    Case report: a rare case of hereditary colorectal cancer and brain tumor with café au lait spots in a child: constitutional mismatch repair deficiency (CMMRD) syndrome by Zubair Khurshid, Mishraz Shaikh, Tarek Talaat Harb Elkadi

    Published 2025-02-01
    “…Hereditary cancers due to mismatch repair deficiency cause colorectal, brain, hematological malignancies, and other tumors in early childhood. Case presentation We present an 11-year-old boy who presented with colorectal cancer and brain tumor due to constitutional mismatch repair deficiency syndrome with a family history of sibling deaths due to brain tumors. …”
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  5. 2725
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  8. 2728

    Blood-based prognostic scores and early dynamics under immunotherapy to select patients with metastatic solid tumors for continuing immune check-point inhibition: a prospective longitudinal study by Javier García-Corbacho, Alberto Indacochea, Iván Victoria, Débora Moreno, Laura Angelats, Azucena E. González Navarro, Laura Mezquita, Fara Brasó-Maristany, Patricia Galván, Begoña Mellado, Nuria Viñolas, Tamara Sauri, Miquel Nogué, Barbara Adamo, Joan Maurel, Estela Pineda, Lydia Gaba, Oscar Reig, Neus Basté, Esther Sanfeliu, Manel Juan, Aleix Prat, Francesco Schettini

    Published 2025-02-01
    “…Abstract Introduction Immune check-point inhibitors (ICI) were a major breakthrough in cancer care, but optimal patient selection remains elusive in most tumors. Methods Overall 173 adult patients with metastatic solid tumors candidates to ICI in clinical trials at our Institution were prospectively recruited. …”
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  9. 2729
  10. 2730

    Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor‐Associated Macrophage by Xiaojiao Sun, Junling Zhang, Bingqi Dong, Qingqing Xiong, Xin Wang, Yanlun Gu, Zhiqi Wang, Huiyu Liu, Jixin Zhang, Xu He, Hongjin Liu, Yi Zhong, Chuxiao Yi, Xiaowei Chi, Zhenming Liu, Xiaocong Pang, Yimin Cui

    Published 2025-01-01
    “…To explore novel drivers of CRC liver metastasis, the transcriptomes of primary paracancerous, colorectal tumors and metastases from human patients are profiled. …”
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  16. 2736

    Diagnostic Accuracy of Next Generation Sequencing Panel using Circulating Tumor DNA in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis by Mariana M. Sebastião, Rodrigo S. Ho, João Paulo V. de Carvalho, Micha Nussbaum

    Published 2020-09-01
    “…**Background/Objectives:** Until now, no meta-analysis has been published to evaluate the diagnostic performance of next-generation sequencing (NGS) panel using circulating tumor (ctDNA) in patients with advanced non-small cell lung cancer (aNSCLC). …”
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  17. 2737

    Association between Interleukin-10-1082 G/A and Tumor Necrosis Factor-α 308 G/A Gene Polymorphisms and Respiratory Distress Syndrome in Iranian Preterm Infants by Abolfazl Khoshdel, Soleiman Kheiri, Peyman Omidvari, Fahimeh Moradi, Majid Hamidi, Hossein Teimori

    Published 2017-01-01
    “…The present study was done to investigate the frequency of interleukin- (IL-) 10 and tumor necrosis factor- (TNF-) α gene polymorphisms and their association with the risk of RDS in preterm infants. …”
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  18. 2738

    Pharmacological Vitamin C-induced high H2O2 generation mediates apoptotic cell death by caspase 3/7 activation in breast cancer tumor spheroids by Ali Mussa, Mahasin Hamid, Khalid Hajissa, Ahmad Hafiz Murtadha, Mohammad A. I. Al-Hatamleh, Noor Fatmawati Mokhtar, Vuk Uskoković, Magdalena Plebanski, Rohimah Mohamud, Rosline Hassan

    Published 2025-01-01
    “…Herein, we investigate the activity and mechanism of action of pharmacological Vit-C on two BC tumor spheroids. Methods We developed two distinct types of BC tumor spheroids from MDA-MB-231 and MCF-7 cells. …”
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  19. 2739
  20. 2740

    Transplante autólogo de células tronco hematopoiéticas em pacientes com tumor de células germinativas refratário: a experiência inicial do Hospital Universitário Walter Cantídio by Daniel Facundo da Silva, Fernando Barroso Duarte, Karine Sampaio Nunes Barroso, João Paulo de Vasconcelos Leitão, Beatriz Stela Gomes de Souza Pitombeira Araujo, Natália Costa Bezerra Freire

    Published 2024-10-01
    “…Introdução: O uso do transplante autólogo de células tronco hematopoiéticas (aTCTH) como tratamento para tumores de órgãos sólidos, ainda que restrito a um grupo pequeno de neoplasias, avançou nos últimos anos, principalmente nos tumores de células germinativas refratários/recidivados (TCG-RR). …”
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