LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model by Ken S. Rosenthal, Sarah Stone, Gary Koski, Daniel H. Zimmerman

“…When administered as a prophylactic vaccination before tumor challenge, J-HER protected against tumor development for at least 48 days. …”
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Integrated microfluidics-based construction of anti-BTN2A2 gel droplet cell preparations for non-invasive tumor-infiltrating lymphocyte therapy by Yishen Tian, Jingxuan Li, Na Yang, Yang Zhao, Jiancao Zuo, Hang Xiong, Yiwen Pan, Li Xiao, Min Su, Feng Han, Zhixu He, Rong Hu

“…Tumor infiltrating lymphocyte therapy (TIL therapy) is one of the effective treatments for solid tumors. …”
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Correlation of serum tumor necrosis factor-α, interleukin-4 and soluble interleukin-2 receptor levels with radiologic and clinical manifestations in active pulmonary tuberculosis by Levent Kart, Hakan Buyukoglan, Ishak O. Tekin, Remzi Altin, Zuhal Senturk, Inci Gulmez, Ramazan Demir, Mustafa Ozesmi

“…We took serum samples from a group of patients with a variety of clinical and radiological stages of pulmonary tuberculosis in order to characterize tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4) and soluble interleukin-2 receptor (sIL-2R) response. …”
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Tumor derived cell‐free nucleic acid upregulates programmed death‐ligand 1 expression in neutrophil via intracellular Toll‐like receptor signaling by Suguru Saito, Duo‐Yao Cao, Tomohiro Shibata, Yan Liu, Aoi Otagiri‐Hoshi, Xiaojiang Cui, Kenneth E. Bernstein

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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection by Amanda R. Loehr, Dennis M. Timmerman, Michelle Liu, Ad J. M. Gillis, Melia Matthews, Jordana C. Bloom, Peter K. Nicholls, David C. Page, Andrew D. Miller, Leendert H. J. Looijenga, Robert S. Weiss

Subjects: “…Testicular germ cell tumor…”
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In Vivo Imaging of Hypoxia-Inducible Factor Regulation in a Subcutaneous and Orthotopic GL261 Glioma Tumor Model Using a Reporter Gene Assay by Sandra Bürgi, Aline Seuwen, Ruth Keist, Johannes vom Berg, Joanes Grandjean, Markus Rudin

“…In vivo experiments were carried out using bioluminescence imaging. Tumors were subsequently analyzed using immunofluorescence staining for hypoxia, endothelial cells, tumor perfusion, and glucose transporter expression. …”
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Importance of NAB2-STAT6 Fusion in the Diagnosis of Pancreatic Solitary Fibrous Tumor with Hamartoma-Like Features: A Case Report and Review of the Literature by Kei Tanaka, Takashi Kishimoto, Masayuki Ohtsuka, Yukio Nakatani, Masaru Miyazaki

“…We report a case of pancreatic hamartoma-like solitary fibrous tumor which was differentiated from pancreatic hamartoma with the detection of NAB2-STAT6 fusion, a specific mutation for solitary fibrous tumors. …”
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In vivo electrical properties of the healthy liver and the hepatic tumor in a mouse model between 1 Hz and 1 MHz during a thermal treatment by Yitong Guo, Weice Wang, Weichen Li, Junyao Li, Mingxu Zhu, Ruteng Song, Wenjing Zhu, Lei Wang, Zhenyu Ji, Xuetao Shi

“…The results demonstrated a linear correlation between k-values and temperatures (R2 > 0.9 for livers and R2 > 0.8 for tumors). Significant differences were observed between livers and tumors at 1, 10 and 50 kHz (p < 0.05). …”
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Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways by Liu Rui, Yu Runze, Cui Yuxin, Fan Mengying, Wang Bo, Zhang Yanmin

“…The aim of this study was to investigate the inhibitory effect of TAD1822-7, a synthesized taspine derivative, on cancer through its effects on tumor cell growth and angiogenesis via suppression of EphrinB2. …”
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Molecular Detection of EMT Markers in Circulating Tumor Cells from Metastatic Non-Small Cell Lung Cancer Patients: Potential Role in Clinical Practice by Annalisa Milano, Francesca Mazzetta, Sabatino Valente, Danilo Ranieri, Laura Leone, Andrea Botticelli, Concetta Elisa Onesti, Salvatore Lauro, Salvatore Raffa, Maria Rosaria Torrisi, Paolo Marchetti

“…Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related mortality; nevertheless, there are few data regarding detection of circulating tumor cells (CTCs) in NSCLC, compared to other kinds of cancers in which their prognostic roles have already been defined. …”
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The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumors: Preliminary Study by Kyriaki Kalokairinou, Achilles Ploumidis, Theodoros Kalogeropoulos, Lampros Vlachos, Kyriakos Stringaris, Ageliki Tavernaraki, Anastasios Thanos, Xenofon Papacharalampous, Vasilios Koutoulidis, Julien Letendre, Olivier Traxer, Athanasios Gouliamos

“…Although conventional cystoscopy is considered to be the gold standard for diagnosis and follow-up of bladder tumors, it remains an invasive and costly procedure. …”
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Oncolytic reprogramming of tumor microenvironment shapes CD4 T-cell memory via the IL6ra-Bcl6 axis for targeted control of glioblastoma by Jeffrey M. Grimes, Sadashib Ghosh, Shamza Manzoor, Li X. Li, Monica M. Moran, Jennifer C. Clements, Sherrie D. Alexander, James M. Markert, Jianmei W. Leavenworth

“…However, the temporal impact on tumor cells and the tumor microenvironment, and the nature of anti-tumor immunity post-therapy remain largely unclear. …”
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Comment on Prognostic Relevance of Primary Tumor Sidedness in Early-Stage Colorectal Cancer: An Integrated Analysis of Four Randomized Controlled Trials (JCOG2003A) by Saloni R. Shah, MBBS, Mansi P. Kevadiya, MBBS, Kenish S. Salewala, MBBS, Yun Yang, MD, PhD, FACS

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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…Initial attempts to develop EpCAM-specific T-cell engagers were unsuccessful due to severe cytokine release effects, as well as serious on-target, off-tumor drug-related toxicities. We developed novel, conditionally active biological (CAB) bispecific antibodies that bind to both EpCAM and CD3 in an acidic tumor microenvironment. …”
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Proximity Labeling-Based Identification of MGAT3 Substrates and Revelation of the Tumor-Suppressive Role of Bisecting GlcNAc in Breast Cancer via GLA Degradation by Bowen Wang, Xin He, Yue Zhou, Zengqi Tan, Xiang Li, Feng Guan, Lei Lei

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Airway Management for Massive Anterior Mediastinal Tumor Resection in an Infant: A Strategy Involving Spontaneous Breathing-Preserving Endotracheal Intubation under Intravenous Anesthesia by Hiromi Matsuda, Ei Ito, Akiko Katsuike, Hirotsugu Okamoto

“…This may be a good airway management strategy for infants with mediastinal tumors or who may be expected to have ventilation difficulties.…”
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Anti-Interleukin-1 Beta/Tumor Necrosis Factor-Alpha IgY Antibodies Reduce Pathological Allergic Responses in Guinea Pigs with Allergic Rhinitis by Hu Wei-xu, Zhou Wen-yun, Zhu Xi-ling, Wen Zhu, Wu Li-hua, Wu Xiao-mu, Wei Hui-ping, Wang Wen-ding, He Dan, Xiang Qin, Hu Guo-zhu

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Giant and irregular pituitary neuroendocrine tumors surgery: comparison of simultaneous combined endoscopic endonasal and transcranial and purely endoscopic endonasal surgery at a single center by Jun Fu, Wenwei Luo, Chunlin Zhang, Zhicheng Wang, Wenjian Fan, Yuanxiang Lin, Dezhi Kang, Jianping Song, Changzhen Jiang, Xiaorong Yan

Subjects: “…Pituitary neuroendocrine tumors…”
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Presence of liver metastasis correlated with high tumor abundance and indicated adverse prognostic feature in EGFR mutation non-small-cell lung cancer patients by Piyada Sitthideatphaiboon, Pronwasun Simseekeaw, Chinachote Teerapakpinyo, Nicha Zungsontiporn, Wariya Chintanapakdee, Itthi Itthisawatpan, Shanop Shuangshoti, Virote Sriuranpong, Thanisa Tongbai, Chanida Vinayanuwattikun

“…The pretreatment ctEGFR detection using the Idylla™ ctEGFR mutation assay served as a surrogate marker for tumor abundance and tumor burden. Presence of liver metastasis was found to be a clinical predictor associated with high tumor abundance and worsening treatment outcomes.…”
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COMPARISON MEASUREMENT AND CALCULATION OF BRAIN TUMOR IN MRI MODALITIES UTILISING SPIN-ECHO PULSE SEQUENCE T1-WEIGHTED CONTRAST AND DIGITAL IMAGE PROCESSING APPLICATIONS by Maizza Nadia Putri, Kusworo Adi, M.Irwan Katili, Sidin Hariyanto, Dwi Rochmayanti

“…Background: Evaluation of brain tumor MRI image results performed by radiologists employing the linear measurement method has several weaknesses and is sensitive to subjectivity. …”
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