Self-administration of augmentation therapy for alpha 1-antitrypsin deficiency by A. Vianello, S. Lococo, L. Corda, M. Torrazza, G. Zuccarini, P. Baderna, F. Cinetto, E. Bargagli, P. Confalonieri, S. Sanduzzi Zamparelli, L. Bertagna De Marchi, B. Molena, F. Lionello, M. Caminati, G. Guarnieri

Get full text

Perbandingan Profil Penderita Tuberkulosis Paru antara Perokok dan Non Perokok di Poliklinik Paru RSUP. Dr. M. Djamil Padang by Cantika Dinia Zulda, Rizanda Machmud, Irvan Medison

“…Salah satu faktor risiko yang dapat menurunkan daya tahan tubuh terhadap bakteri Mycobacterium tuberculosis adalah faktor merokok. Menurut Public Health Agency of Canada terdapat hubungan yang erat antara merokok dengan TB. …”
Get full text

Survey on the Status and Training Demands of Capabilities for Diagnosing and Treating Common Diseases of Primary Care General Practitioners in Hunan Province by LI Lingqi, GAO Yinyan, ZHANG Yuqin, SUN Dingkui, WU Xinyin, ZHANG Weiru

“…The results show that 75.1% (253/337) of participants consider themselves competent in the diagnosis and treatment of common diseases; 16.6% (56/337) of participants reported a lack of competence in certain diseases, with the top six including depression[89.3% (50/56) ], stress incontinence[69.6% (39/56) ], dementia[66.1% (37/56) ], stroke[53.6% (30/56) ], co-morbidities[51.8% (29/56) ]and tuberculosis[46.4% (26/56) ]. These findings consistent between community and township respondents. …”
Get full text

Challenges in diagnosis and treatment of cushing disease in a 12-year-old boy. Case report by Agim Gjikopulli, Sonila Tomori, Marjeta Tanka, Donjeta Bali

“…An ectopic ACTH-dependent Cushing syndrome was suspected together with neuroendocrine neoplasia (carcinoid tumor) as a thoracic CT showed a nodular lesion with regular-lobulated sharp contours in the lower lobe of the right lobe resulted in pulmonary tuberculosis granuloma. Even imaging failed to identify the ACTHsecreting microadenoma; the decisive examination was an intervention to collect samples from the inferior petrosal sinus during the CRH test, which found a left-side ACTH-secreting focus. …”
Get full text

Pelvic Actinomycosis by Alejandra García-García, Ninfa Ramírez-Durán, Horacio Sandoval-Trujillo, María del Socorro Romero-Figueroa

“…Its symptomatology imitates some malignant pelvic tumours, tuberculosis, or nocardiosis, causing abscesses and fistulas. …”
Get full text

Towards a unified regional surveillance system: the Gulf CDC’s first initiatives by Sami Al Mudarra, Lamis Alghamdi, Ahmed AlHatlan, Andrew Amato Gauci, Aleksandra Polkowska Kramek, Alaa Alqurashi, Nouf Alzuhayri, Sadeem AlShiban, Bushra Alghamdi, Pasi Penttinen

“…The final agreed list of diseases and conditions for the pilot are the CDs: acute respiratory infection (ARI), endemic dengue, brucellosis, measles and pulmonary tuberculosis together with the NCDs: cancer (registry) and road traffic injuries. …”
Get full text

A case series of melioidosis: An underdiagnosed entity in Kerala by Ebrahimkutty Shanimole Puthenpurayil, Pulikottil Shoba Kurian, Alexander Vipin Sam

“…Clinical manifestations are protean varying from asymptomatic infection, multiple skin abscesses, chronic pneumonia mimicking tuberculosis, and fulminant septic shock with abscesses in multiple internal organs. …”
Get full text

Mycobacteria in Terrestrial Small Mammals on Cattle Farms in Tanzania by Lies Durnez, Abdul Katakweba, Harrison Sadiki, Charles R. Katholi, Rudovick R. Kazwala, Robert R. Machang'u, Françoise Portaels, Herwig Leirs

“…The control of bovine tuberculosis and atypical mycobacterioses in cattle in developing countries is important but difficult because of the existence of wildlife reservoirs. …”
Get full text

Clinical Presentation and Magnetic Resonance Findings in Sellar Tuberculomas by Dulce Bonifacio-Delgadillo, Yolanda Aburto-Murrieta, Citlaltepetl Salinas-Lara, Julio Sotelo, Ivonne Montes-Mojarro, Arturo Garcia-Marquez

“…The tuberculous infection of the pituitary gland and sellar region is characterized by the presence of an acute or chronic inflammatory reaction and may occur in the absence of systemic tuberculosis. The diagnosis is difficult prior to the surgery. …”
Get full text

Biological function of d-tryptophan: a bibliometric analysis and review by Fei Wang, Runyu Du, Yunxiao Shang

“…Furthermore, d-tryptophan plays a role in the therapy of atherosclerosis, osteoporosis, tuberculosis, and cancer.ConclusionThe results of bibliometric analysis highlight that future research should focus on the biological functions of d-tryptophan as a food preservative and its use in immunomodulation and drug development, providing strong guidance for future research.…”
Get full text

Candida tropicalis spondylitis in a non-tropical immunocompetent patient: a case report and review of the literature by Hong Yang, Xin Wang, Weijian Zhu, Bei Zhou

“…After 3 weeks of empirical anti-tuberculosis therapy, the patient’s symptoms did not improve, prompting posterior lesion debridement and autologous iliac bone grafting with pedicle screw fixation. …”
Get full text

Differentially Expressed Genes Study Shown Potential for BCG Stimulation in Reducing the Severity of COVID-19 by Irandi Putra Pratomo, Aryo Tedjo, Dimas R Noor, Wisnu Ananta Kusuma

“…The incidence of COVID-19 infection and death is known to be lower in tuberculosis (TB) endemic countries than in nonendemic countries. …”
Get full text

Incidental Finding of Nocardia: A Case Series from a Tertiary Care Centre in Uttarakhand by Aroop Mohanty, Suneeta Meena, Subodh Pandey Kumar, Puneet Kumar Gupta, Neelam Kaistha, Pratima Gupta, Mithilesh Kumar Jha, Sasi Rekha

“…The most common conditions causing immunosuppression were type II DM, COPD, and pulmonary tuberculosis.…”
Get full text

Endometriosis-Associated Massive Ascites in an Asian Woman: A Case Report of a Rare Clinical Entity by Nuntasiri Eamudomkarn, Naratassapol Likitdee, Pilaiwan Kleebkaow, Chumnan Kietpeerakool

“…Abdominal paracentesis was performed to yield fluid samples for evaluation, which revealed no malignant cells, and polymerase chain reaction (PCR) was negative for tuberculosis. The patient underwent exploratory laparotomy which revealed a large amount of serosanguinous ascites, thickened matted bowel loops, and necrotic debris covering the entire surface of the peritoneum and visceral organs. …”
Get full text

The Value of Routine Polymerase Chain Reaction Analysis of Intraocular Fluid Specimens in the Diagnosis of Infectious Posterior Uveitis by Marius A. Scheepers, Karin A. Lecuona, Graeme Rogers, Catey Bunce, Craig Corcoran, Michel Michaelides

“…PCR analysis was performed for cytomegalovirus, varicella zoster virus, herpes simplex virus types 1 and 2, Toxoplasma gondii, and Mycobacterium tuberculosis. Results. PCR analysis confirmed the initial clinical diagnosis in 55 patients (35%) and altered the initial clinical diagnosis in 36 patients (23%). …”
Get full text

Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy by Bipin Kishore Prasad, Yamuna Ranganathan, Gunjan Dwivedi, Devika Gupta

“…Conclusion: While ruling out tuberculosis, Epstein Barr-Virus infection, acute bacterial lymphadenitis or malignant disease, Cat Scratch Disease should be included in the differential diagnosis of lymphadenopathies in head-neck region so that possibility of antibiotic abuse, an unnecessary biopsy, long term antitubercular drug therapy or even surgical treatment may be avoided. …”
Get full text

Mycobacterium bovis: A Model Pathogen at the Interface of Livestock, Wildlife, and Humans by Mitchell V. Palmer, Tyler C. Thacker, W. Ray Waters, Christian Gortázar, Leigh A. L. Corner

“…Today, reservoirs of Mycobacterium bovis, the causative agent of tuberculosis in animals, and sometimes humans, exist in a range of countries and wild animal populations. …”
Get full text

Salicylanilide Diethyl Phosphates as Potential Inhibitors of Some Mycobacterial Enzymes by Martin Krátký, Eva Novotná, Shalini Saxena, Perumal Yogeeswari, Dharmarajan Sriram, Markéta Švarcová, Jarmila Vinšová

“…The enzymes are related to the nongrowing state of Mycobacterium tuberculosis. Salicylanilide diethyl phosphates represent new candidates with significant inhibitory activity especially against L-alanine dehydrogenase. …”
Get full text

Expression and Secretion of CXCL-8 and CXCL-10 From <emph>Mycobacterium Bovis</emph> BCG-Infected Human Epithelial Cells: Role of IL-4

“…Interleukin(IL)-4 is one of the cytokines that are the hallmark of the Th-2 response, and plays an important role in human tuberculosis. In the current study, we investigated the effect of IL-4 on chemokine production by human epithelial cells infected with <emph>Mycobacterium bovis</emph> bacillus calmette-guérin (BCG). …”
Get full text

Childhood-onset enthesitis-related arthritis leading to nephrotic syndrome due to secondary amyloidosis complicated by acute pulmonary embolism - The domino effect by Vishal Mangal, Bhaskar Datt, Arun Hegde, A W Kashif, Ankit Kumar, Jaspreet Kaur, Nidhi Goel, Anil Shankar Menon

“…In the past, chronic infections, mainly, tuberculosis were the most common cause of AA amyloidosis in India; however, chronic inflammatory arthropathies have become the most common cause of AA amyloidosis in India over the past three to four decades. …”
Get full text