CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

Subjects: “…Early phase trials…”
Get full text

Fermented Ophiocordyceps sinensis mycelium products for preventing contrast-associated acute kidney injury: a systematic review of randomized controlled trials by Fenglan Pu, Tianli Li, Chen Shen, Yingqiao Wang, Chunmei Tang, Xiaowen Zhang, Lijiao Yan, Qihe Xu, Jianping Liu

Subjects: Get full text

TAD-SIE: sample size estimation for clinical randomized controlled trials using a Trend-Adaptive Design with a Synthetic-Intervention-Based Estimator by Sayeri Lala, Niraj K. Jha

Subjects: “…Clinical randomized controlled trials…”
Get full text

The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled tria... by Zehua Zhang, Shiyun Tang, Shiyu Liu, Yulin Leng, Xiaoxu Fu, Hongyan Xie, Hong Gao, Hong Gao, Chunguang Xie, Chunguang Xie

Subjects: “…randomized controlled trials…”
Get full text

Grammar-constrained decoding for structured information extraction with fine-tuned generative models applied to clinical trial abstracts by David M. Schmidt, Philipp Cimiano

Subjects: Get full text

Impact of subgingival periodontal treatment on systemic markers of inflammation in patients with metabolic syndrome: a systematic review of randomized clinical trials by Marie Chavez, Asshly Ramirez, Akram Hernández-Vásquez, Daniel Comandé, Diego Azañedo

Subjects: Get full text

Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Experience from the RADA... by Lina Jarutyte, Jan Petr, Nicholas Turner, Patrick G. Kehoe, Henk-Jan Mutsaerts, David L. Thomas

Subjects: “…Multi-centre randomised controlled trials…”
Get full text

Evaluating the overall renal outcomes of sodium-glucose cotransporter-2 (SGLT2) inhibitors in patients with chronic kidney disease (CKD) by Min-Jia Cao, Ting-Ting Liang, Li Xu, Fang-Hong Shi

Subjects: “…Randomized controlled trials…”
Get full text

Comparative the efficacy and safety of Gosuranemab, Semorinemab, Tilavonemab, and Zagotenemab in patients with Alzheimer’s disease: a systematic review and network meta-analysis of... by Wenting Cai, Wenting Cai, Hui Zhang, Hui Zhang, Yan Wu, Yan Wu, Yao Yao, Jinping Zhang

Subjects: “…randomized controlled trials…”
Get full text

Predicting accrual success for better clinical trial resource allocation by Sisi Ma, Yinzhao Wang, John Wagner, Steve Johnson, Serguei Pakhomov, Constantin Aliferis

Subjects: “…Clinical trial…”
Get full text

Effects of dipeptidyl peptidase 4 inhibitors on the risk of acute respiratory failure in patients with type 2 diabetes mellitus: a meta-analysis of cardiovascular outcomes trials by Yan Wang, Caiyuan Yu, Xiaoyan Zheng, Yaya Wang, Wei Zhang

Subjects: “…cardiovascular outcomes trials…”
Get full text

Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives by Fatima Aldali, Chunchu Deng, Mingbo Nie, Hong Chen

Subjects: “…clinical trials…”
Get full text

Challenges and ongoing initiatives towards better integrated EU scientific advice by Iordanis Gravanis, Michael Berntgen, Spiros Vamvakas, Pierre Demolis, Paolo Foggi

Subjects: Get full text

From Clinical Trial Evidence to Clinical Guidelines: Perspectives on REWIND from Clinicians in the Gulf and Levant Region by Talal Ashour, Sami Azar, Akram Echtay, Muhammad Farooqi, Tarek Fiad, Mohamed Hassanein, Ahmed Hassoun, Abdul Jabbar, Amin Jayyousi, Kari Ranta, Hani Sabbour, Fatih Tangi, Ibrahim Turfanda

Subjects: “…cardiovascular outcomes trials…”
Get full text

The combination of kidney function variables with cell cycle arrest biomarkers identifies distinct subphenotypes of sepsis-associated acute kidney injury: a post-hoc analysis (the... by Dimitri Titeca-Beauport, Momar Diouf, Delphine Daubin, Ly Van Vong, Guillaume Belliard, Cédric Bruel, Yoann Zerbib, Christophe Vinsonneau, Kada Klouche, Julien Maizel

Subjects: “…The AKI-CHECK study was registered at ClinicalTrials.gov (NCT02812784)…”
Get full text

ury Trial Outside Criminal Justice: Global Experience by M. I. Modebadze

Subjects: “…jury trial…”
Get full text

Building a diverse national research advisory board by Gayle Valensky, Jeff B. Pawelek, Lauren Serpico, David Rodriguez, Maribel Pieters, Yulissa Perez, Julia Moore Vogel

Subjects: “…diversity and inclusion in clinical trials…”
Get full text

Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

Subjects: Get full text

La naissance de la justice en débat : représentations contemporaines du procès d’Oreste by Claire Lechevalier

Subjects: “…trial…”
Get full text

« Petty treason » dans son contexte : genre et verdicts dans les procès pour meurtre entre conjoints aux assises du tribunal d’Old Bailey à Londres, Angleterre, 1674-1790 by Andrea McKenzie

Subjects: “…trial…”
Get full text