Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block by Ruyue Xue, Yuexian Li, Mei Zhan, Lin Yang, Defeng Sun

“…BackgroundThis study evaluates the impact of ultrasound-guided stellate ganglion block (SGB) on early postoperative cognitive dysfunction (POCD) in elderly patients who underwent laparoscopic gastrointestinal (GI) surgery, as well as its potential effect on oxidative stress and inflammatory responses.MethodsIn this randomized controlled trial, 104 elderly patients scheduled for elective laparoscopic GI surgery were randomized to receive ultrasound-guided SGB before general anesthesia (SGB group) or general anesthesia alone (control group). …”
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ChatGPT-4 Performance on German Continuing Medical Education—Friend or Foe (Trick or Treat)? Protocol for a Randomized Controlled Trial by Christian Burisch, Abhav Bellary, Frank Breuckmann, Jan Ehlers, Serge C Thal, Timur Sellmann, Daniel Gödde

“…ResultsAs of October 2024, the acquisition of data and students to participate in the trial is ongoing. Upon analysis of our acquired data, we predict our findings to be ready for publication as soon as early 2025. …”
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The effect of Camellia sinensis ointment on perineal pain and episiotomy wound healing in primiparous women: A triple-blind randomized clinical trial. by Masoumeh Sayahi, Azam Jahangirimehr, Zahra Hatami Manesh, Faraz Mojab, Maryam Nikbina

“…URL of registry: https://en.irct.ir/trial/41326.…”
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Three-Dimensional Electrical Impedance Imaging During Spontaneous Breathing Trials in Patients With Acute Hypoxic Respiratory Failure: A Pilot Study by Nilton Barbosa da Rosa, Jr, MS, Tzu-Jen Kao, MD, PhD, John Brinton, PhD, Patrick J. Offner, Ellen L. Burnham, MD, Jennifer L. Mueller, PhD

“…The purpose of this work is to evaluate the feasibility of lung imaging using 3D electrical impedance tomography (EIT) during spontaneous breathing trials (SBTs) in patients with acute hypoxic respiratory failure. …”
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Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

“…Study results will be disseminated via research conference presentations and peer-reviewed publications.Trial registration number NCT02941809.…”
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Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial by Tuomo Alanko, Akseli Hemminki, Víctor Cervera-Carrascón, Riikka Havunen, Kristian Taipale, Dafne C A Quixabeira, Jorma Sormunen, Katriina Peltola, Suvi Sorsa, Santeri A Pakola, Elise Jirovec, Lyna Haybout, Claudia Kistler, Tatiana V Kudling, Victor Arias, James H A Clubb, Mirte van der Heijden, Teijo Pellinen, Joao M Santos

“…TUNIMO (NCT04695327) was a phase I clinical trial using TILT-123 in patients with advanced solid tumors aiming to assess the safety, efficacy, and immunological effects of TILT-123. …”
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Lipidomic and Instrumental Evaluation of a Melatonin-Based In & Out Strategy Versus Topical Treatment in Skin Aging: A Randomized Prospective Trial by Francesca Colombo, Stefano Alfano, Massimo Milani

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N-Butyl-2-Cyanoacrylate Adhesive Versus Absorbable Tacks in Laparoscopic Groin Hernia Repair: A Multicenter Randomized Clinical Trial by Clayton C. Petro, MD, Benjamin K. Poulose, MD, Michael J. Rosen, MD, Alfredo M. Carbonell, II, DO, Adel G. El-Ghazzawy, MD, Jeremy A. Warren, MD, Emanuele Lo Menzo, MD, Ajita S. Prabhu, MD, David M. Krpata, MD, Samuel Szomstein, MD, Vimal Narula, MD, Crystal F. Totten, MD, Kelly R. Haisley, MD, Andrew C. Bernard, MD, Henrik O. Berdel, MD, Jessica K. Reynolds, MD, Zachary D. Warriner, MD, John S. Roth, MD

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Bimanual Microincision Cataract Surgery versus Coaxial Microincision Cataract Surgery: A Meta-Analysis of Randomized Controlled Trials and Cohort Studies by Chenxi Fu, Naipin Chu, Xiaoning Yu, Ke Yao

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A web-based pilot randomized controlled trial to test the efficacy of education and contact-based interventions in reducing public suicide stigma by Nathalie Oexle, Matthias Lühr, Daniele Valacchi, Nicolas Rüsch

“…Methods We conducted a web-based randomized controlled trial among N = 2,043 participants recruited from an established online research panel. …”
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Psychological counselling interventions to improve perceived quality of life and counter anxiety and depression in pulmonary-arterial-hypertension patients: A clinical trial by Emilia TARANTINO, Pietro CRESCENZO, Maria CAMPOBASSO, Francesca D’ALESSANDRO, Paola ARGIENTO, Emanuele ROMEO, Stefano GHIO, Patrizio VITULO, Francesco PARISI, Massimiliano MULÈ, Carlo ALBERA, Carmine Dario VIZZA, Michele D’ALTO

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Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial by Mohammad Jafar Eghbal, Ali Haeri, Arash Shahravan, Ali Kazemi, Fariborz Moazami, Mohammad Ali Mozayeni, Eshaghali Saberi, Mohammad Samiei, Mehdi Vatanpour, Alireza Akbarzade Baghban, Mahta Fazlyab, Ardavan Parhizkar, Mahboobe Ahmadi, Nazila Akbarian Rad, Shima Bijari, Delaram Bineshmarvasti, Paria Davoudi, Roya Dehghan, Mandana Dehghani, Habibollah Ebrahimi, Nafiseh Emami, Nafiseh Farajian, Rahim Fereidooni, Gelareh Ghobadi, Mostafa Ghodrati, Atefeh Gohari, Azadeh Hashemi, Mohammadreza Hosseini, Elham Karami, Nasir Kheirabadi, Sepideh Kozegari, Hadi Labaf Ghasemi, Alireza Majidi, Parastu Malekzadeh, Vahid Mehrabi, Mehrnush Mohammadi, Leila Moradi Eslami, Atefeh Noghani, Negin Omatali, Negar Pourhatami, Behnam Rahbani Nobar, Saeid Rahmani, Parviz Shafaq, Sara Soofiabadi, Somaye Teimoori, Farzaneh Vatandoost, Saeed Asgary

“…This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. …”
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Impact of cooling diabetic patients’ fingertips compared to vibrating stimulation on pain from the glucometer needle: A cross-over trial study by Vahid Vejdanihemmat, Hiva Azami, Leili Tapak, Shiva Borzouei, khodayar Oshvandi

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A Randomized Clinical Trial of a Functional Electrical Stimulation Mimic to Gait Promotes Motor Recovery and Brain Remodeling in Acute Stroke by Xiuyuan Zheng, Danfeng Chen, Tiebin Yan, Dongmei Jin, Zhiqiang Zhuang, Zhimei Tan, Wei Wu

“…In conclusion, when four-channel FES induces cycling movement of the lower extremities based on a gait pattern, it may be more effective in promoting motor recovery and induce more plastic changes and brain remodeling than two-channel stimulation. This trial is registered with clinical trial registration unique identifier ChiCTR-TRC-11001615.…”
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Evaluation of Randomised Controlled Trials Published in Indian Specialty Dental Journals for Statistical Testing of Baseline Differences: A Meta-Epidemiological Study by Mahesh R. Khairnar, PG Naveen Kumar, Ananta Kusumakar, Zainab Akram, Harloveen Sabharwal, Sachin Jadhav

Subjects: “…randomised controlled trials…”
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Analgesic Effect of Passive Range-of-Motion Exercise on the Healthy Side for Pain after Total Knee Arthroplasty: A Prospective Randomized Trial by Shuichi Eto, Motoki Sonohata, Yasuo Takei, Masaya Ueno, Norio Fukumori, Masaaki Mawatari

“…In this prospective randomized controlled trial, participants were randomly assigned to two groups: a bilateral group that received bilateral exercise on the operated and healthy sides and a unilateral group that received exercise therapy only on the affected side. …”
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Effects of Customized Progressive Addition Lenses vs. Single Vision Lenses on Myopia Progression in Children with Esophoria: A Randomized Clinical Trial by Xiaowei Zhu, Dongmei Wang, Naiyang Li, Feng Zhao

“…Ninety-three Chinese children, aged 7–14 years with spherical equivalent refraction (SER) ranging from −0.50 to −4.00 D and near esophoria ≥2Δ, were randomly assigned into a CPALs (n = 46) and an SVLs group (n = 47) for a 2-year, double-masked, randomized trial. The primary outcome measure was the progression of myopia, as determined by cycloplegic autorefraction. …”
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Needle Tip Position and Bevel Direction Have No Effect in the Fluoroscopic Epidural Spreading Pattern in Caudal Epidural Injections: A Randomized Trial by Won Kyoung Kwon, Ah Na Kim, Pil Moo Lee, Cheol Hwan Park, Jae Hun Kim

“…We conducted a prospective randomized trial to determine if the needle position and bevel direction have any effect on the epidural spreading pattern in CESI. …”
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A health-education intervention to improve outcomes for children with emotional and behavioural difficulties: protocol for a pilot cluster randomised controlled trial by Rachel Schembri, Harriet Hiscock, Frank Oberklaid, William Garvey

“…Schools and caregivers will be provided with a report of the study outcomes and implications at the completion of the study.Trial registration number ACTRN12621000652875.…”
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Leaflet: Operative Steps for Interventional Studies in Neuroscience by Maria Meringolo, Sergio Delle Monache, Giuseppina Martella, Antonella Peppe

Subjects: “…clinical trials…”
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