Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial by David Evans, Francesco Negro, Michail Arvanitidis, Eduardo Martinez-Valdes, Ragul Selvamoorthy, Patricio Pincheira

“…The results of this study will be disseminated in peer-reviewed journals and at international conferences.Trial registration number ISRCTN15821610.…”
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Application of probiotics, prebiotics and synbiotics in patients with breast cancer: a systematic review and meta-analysis protocol for randomised controlled trials by Wenjie Liu, Wenyao Cui, Xinrong Chen, Dan Duan, Maojun Chen

“…This protocol aims to explore the effectiveness and safety of probiotics, prebiotics and synbiotics in patients with breast cancer.Methods and analysis We will search the following electronic databases for relevant randomised controlled trials: PubMed, EMBASE, Cochrane Library and Web of Science. …”
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Efficacy and safety of repetitive transcranial magnetic stimulation in the treatment of male smokers with tobacco use disorder: a randomized controlled trial by Salma W. Mousa, Adel A. Badawy, Gehan F. Attia, Wesam A. Ghareeb

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Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study by Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

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Baricitinib for the Management of SARS-CoV-2-Infected Patients: A Systematic Review and Meta-Analysis of Randomised Controlled Trials by Sivananthan Manoharan, Lee Ying Ying

“…Four randomised controlled trials (RCTs) were included. Based on the meta-analysis, baricitinib statistically significantly reduced mortality with the risk ratio (RR) of RR = 0.74 [95% CI: 0.58 to 0.94; p=0.01] and moderately high heterogeneity, where I2 = 62% and p=0.05. …”
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Protocol for process evaluation of SMART Mental Health cluster randomised control trial: an intervention for management of common mental disorders in India by Anushka Patel, David Peiris, Pallab K Maulik, Graham Thornicroft, Shekhar Saxena, Sudha Kallakuri, Amanpreet Kaur, Siddhardha Devarapalli, Mercian Daniel, Beverley M Essue, Shashi Kant, D Praveen, Usha Raman, Rajesh Sagar, Ankita Mukherjee

“…Findings of the study will be disseminated through peer-reviewed publications, stakeholder meetings, digital and social media platforms.Trial registration number CTRI/2018/08/015355.…”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…The results will be published according to the Consolidated Standards of Reporting Trials guidelines in a peer-reviewed journal.Trial registration number NCT03112928; Pre-results.…”
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Time to intubation with McGrath™ videolaryngoscope versus direct laryngoscope in powered air-purifying respirator: a randomised controlled trial by Qing Yuan Goh, Sui An Lie, Zihui Tan, Pei Yi Brenda Tan, Shin Yi Ng, Hairil Rizal Abdullah

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Anaesthetic efficacy of intraligamentary injection compared to incisive nerve block using 3% mepivacaine hydrochloride: a randomized clinical trial by Suzan Salem, Islam Saad, Ramy Elmoazen, Ghada Amin Khalifa

“…The results suggest that ILI can be used as a sole anaesthetic technique during extraction of lower anterior and premolar teeth. Trial registration This trial was retrospectively registered on 27/01/2023 with the identifier ISRCTN83272316 in Isrctn.com.…”
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Letter to the Editor Regarding “Analgesic Effectiveness of Truncal Plane Blocks in Patients Undergoing the Nuss Procedure: A Randomized Controlled Trial” by Guanyu Yang, Qinjun Chu

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Multicenter Randomized Controlled Trial Comparing the Contribution of Proxabrushes with Regular Toothbrushes and Only Regular Toothbrushes to the Oral Health of Thai Elderly by Orachad Gururatana, Warangkana Vejvithee, Narisa Ekpatcha

“…Multicenter randomized controlled trial, parallel grouped, open label, blocked randomization was used at each province to allocate treatment. …”
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Lung and blood early biomarkers for host-directed tuberculosis therapies: Secondary outcome measures from a randomized controlled trial. by Robert S Wallis, Sibuse Ginindza, Trevor Beattie, Nishanee Arjun, Morongwe Likoti, Modulakgotla Sebe, Vinodh A Edward, Mohammed Rassool, Khatija Ahmed, Katherine Fielding, Bintou A Ahidjo, Mboyo D T Vangu, Gavin Churchyard

“…<h4>Methods</h4>Biomarkers of inflammation and microbicidal activity were evaluated as a part of a recent phase-2 randomized controlled trial of four HDTs in 200 patients with pulmonary tuberculosis and baseline predictors of poor outcome, including CC-11050 (PDE4i), everolimus (mTORi), auranofin (oral gold salt), and ergocalciferol (vitamin D). …”
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Technology to improve reliable access to oxygen in Western Uganda: study protocol for a phased implementation trial in neonatal and paediatric wards by Graham Moore, Hamish Graham, Rami Subhi, Sheillah Bagayana, Joseph Mugerwa, David Peake, Eleanor Nakintu, Daniel Murokora, Roger Rassool, Marc Sklar, Bryn Sobott

“…Broader dissemination will include publication in peer-reviewed journals and academic conference presentations.Trial registration number ACTRN12621000241831.…”
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Prophylactic Therapy of Silymarin (Milk Thistle) on Antituberculosis Drug-Induced Liver Injury: A Meta-Analysis of Randomized Controlled Trials by Lina Tao, Xiaoyu Qu, Yue Zhang, Yanqing Song, Si-xi Zhang

“…We searched MEDLINE, PubMed, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) up to 30th November 2018. Randomized controlled trials (RCTs) that compared silymarin and placebo to prevent anti-TB DILI were included. …”
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The case for development of a core outcome set (COS) and supplemental reporting guidelines for influenza vaccine challenge trial research in swine by Sheila Keay, Famke Alberts, Annette M. O’Connor, Robert Friendship, Terri O’Sullivan, Zvonimir Poljak

“…Previously, we systematically reviewed more than 20 years of influenza vaccine challenge trial research in pigs to answer the question, “does vaccinating sows protect offspring?” …”
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Effect of the cervical and thoracic “Daoyin” training on posture and pulmonary function in patients with upper crossed syndrome: a randomized controlled trial by Yue Guo, Ming Li, Chaowei Xie, Xiaoyan Liu, Yushan Chen, Jun Yang, Yuxue Wu, Shaoqing Chen, Shizhong Wang, Jianping Lin

“…Conclusion Cervical and thoracic “Daoyin” training can improve the abnormal posture of head forward and round shoulders, reducing pain and anxiety, improving cervical spine function, and improving lung function to a certain extent. Trial registration ChiCTR2300072669 (20/06/2023), Prospective registration, www.chictr.org.cn .…”
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Comparison of the recovery profile of sufentanil and remifentanil in total intravenous anesthesia: a systematic review and meta-analysis of randomized controlled trials by Igor Seror Cuiabano, Rafael Pagliaro Naves, Rodrigo Bouchabki de A. Diehl

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Virtual reality-based cognitive–behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction: a randomised clinical trial by Jiajun Weng, Junbo Ge, Jiajia Liu, Juying Qian, Xiao Huang, Yuanyuan Li, Juan Peng, Yan'e Lu, Dong Huang, Pingyuan Yang, Shikun Xu, Lihua Guan, Qibing Wang, Zexin Zhao, Yabin Wei

“…Cybersickness was the main reported adverse event (n=5).Conclusions Our results indicate that VR-CBT can significantly reduce post-AMI anxiety at the acute stage of the illness; the improvement was maintained at the 3-month follow-up.Trial registration number The trial was registered at www.chictr.org.cn with the identifier: ChiCTR2200066435.…”
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The Effectiveness and Safety of Mesenchymal Stem Cells in the Treatment of Osteoarthritis: A Systematic Review and Meta-analysis of 28 Randomized Controlled Trials by Zhiyong Long, Mingsheng Zhang, Tianqing Zhang, Liuting Zeng, Kailin Yang, Tiejun Yang, Ganpeng Yu, Jun Li, Yang Wu, Hua Chen

“…Chinese databases (such as CNKI and SinoMed) and English databases (such as PubMed and Embase) were searched to collect randomized controlled trials (RCTs) of MSCs in the treatment of OA. The retrieval time is from inception to October 10, 2021. …”
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A meta-analysis of randomized controlled trials: evaluating the efficacy of isokinetic muscle strengthening training in improving knee osteoarthritis outcomes by Wanqin Guo, Jingyang Gao, Dawazhuoma, Xiuling Mi, Ciwang, Bianba

“…The quality of evidence the studies reported was poor, mainly due to original trials with high inter-study heterogeneity and imprecise results. …”
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